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Volumn 6, Issue 7, 2011, Pages

Secreted human amyloid precursor protein binds semaphorin 3a and prevents Semaphorin-Induced growth cone collapse

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ISOPROTEIN; LIGAND; SEMAPHORIN 3A; APP PROTEIN, HUMAN; PEPTIDE FRAGMENT;

EID: 79960925905     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022857     Document Type: Article
Times cited : (12)

References (56)
  • 1
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ, (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8: 101-12.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 2
    • 34248547813 scopus 로고    scopus 로고
    • Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases
    • Ferreira ST, Vieira MN, De Felice FG, (2007) Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases. IUBMB Life 59: 332-45.
    • (2007) IUBMB Life , vol.59 , pp. 332-345
    • Ferreira, S.T.1    Vieira, M.N.2    De Felice, F.G.3
  • 3
    • 0026767361 scopus 로고
    • Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage
    • Hung AY, Koo EH, Haass C, Selkoe DJ, (1992) Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage. Proc Natl Acad Sci USA 89: 9439-9443.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9439-9443
    • Hung, A.Y.1    Koo, E.H.2    Haass, C.3    Selkoe, D.J.4
  • 4
    • 0028329090 scopus 로고
    • The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis
    • Moya KL, Benowitz LI, Schneider GE, Allinquant B, (1994) The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis. Dev Biol 161: 597-603.
    • (1994) Dev Biol , vol.161 , pp. 597-603
    • Moya, K.L.1    Benowitz, L.I.2    Schneider, G.E.3    Allinquant, B.4
  • 5
    • 34248172449 scopus 로고    scopus 로고
    • Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts
    • Gralle M, Ferreira ST, (2007) Structure and functions of the human amyloid precursor protein: the whole is more than the sum of its parts. Prog Neurobiol 82: 11-32.
    • (2007) Prog Neurobiol , vol.82 , pp. 11-32
    • Gralle, M.1    Ferreira, S.T.2
  • 6
    • 0031453752 scopus 로고    scopus 로고
    • The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity
    • Perez RG, Zheng H, Van der Ploeg LH, Koo EH, (1997) The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity. J Neurosci 17: 9407-9414.
    • (1997) J Neurosci , vol.17 , pp. 9407-9414
    • Perez, R.G.1    Zheng, H.2    van der Ploeg, L.H.3    Koo, E.H.4
  • 7
    • 37549040612 scopus 로고    scopus 로고
    • A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference
    • Young-Pearse TL, Bai J, Chang R, Zheng JB, LoTurco JJ, et al. (2007) A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J Neurosci 27: 14459-14469.
    • (2007) J Neurosci , vol.27 , pp. 14459-14469
    • Young-Pearse, T.L.1    Bai, J.2    Chang, R.3    Zheng, J.B.4    LoTurco, J.J.5
  • 8
    • 0026663993 scopus 로고
    • The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
    • Milward EA, Papadopoulos R, Fuller SJ, Moir RD, Small D, et al. (1992) The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron 9: 129-137.
    • (1992) Neuron , vol.9 , pp. 129-137
    • Milward, E.A.1    Papadopoulos, R.2    Fuller, S.J.3    Moir, R.D.4    Small, D.5
  • 9
    • 0028136865 scopus 로고
    • Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension
    • Jin LW, Ninomiya H, Roch JM, Schubert D, Masliah E, et al. (1994) Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J Neurosci 14: 5461-5470.
    • (1994) J Neurosci , vol.14 , pp. 5461-5470
    • Jin, L.W.1    Ninomiya, H.2    Roch, J.M.3    Schubert, D.4    Masliah, E.5
  • 10
    • 0028213567 scopus 로고
    • A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
    • Small DH, Nurcombe V, Reed G, Clarris H, Moir R, et al. (1994) A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J Neurosci 14: 2117-2127.
    • (1994) J Neurosci , vol.14 , pp. 2117-2127
    • Small, D.H.1    Nurcombe, V.2    Reed, G.3    Clarris, H.4    Moir, R.5
  • 11
    • 0026623085 scopus 로고
    • Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells
    • LeBlanc AC, Kovacs DM, Chen HY, Villaré F, Tykocinski M, et al. (1992) Role of amyloid precursor protein (APP): study with antisense transfection of human neuroblastoma cells. J Neurosci Res 31: 635-645.
    • (1992) J Neurosci Res , vol.31 , pp. 635-645
    • LeBlanc, A.C.1    Kovacs, D.M.2    Chen, H.Y.3    Villaré, F.4    Tykocinski, M.5
  • 12
    • 0028963635 scopus 로고
    • Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro
    • Allinquant B, Hantraye P, Mailleux P, Moya K, Bouillot C, et al. (1995) Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro. J Cell Biol 128: 919-927.
    • (1995) J Cell Biol , vol.128 , pp. 919-927
    • Allinquant, B.1    Hantraye, P.2    Mailleux, P.3    Moya, K.4    Bouillot, C.5
  • 13
    • 34247349579 scopus 로고    scopus 로고
    • A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching
    • Ikin AF, Sabo SL, Lanier LM, Buxbaum JD, (2007) A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching. Mol Cell Neurosci 35: 57-631.
    • (2007) Mol Cell Neurosci , vol.35 , pp. 57-631
    • Ikin, A.F.1    Sabo, S.L.2    Lanier, L.M.3    Buxbaum, J.D.4
  • 14
    • 70349557615 scopus 로고    scopus 로고
    • Emerging mechanisms in morphogen-mediated axon guidance
    • Sánchez-Camacho C, Bovolenta P, (2009) Emerging mechanisms in morphogen-mediated axon guidance. Bioessays 31: 1013-1025.
    • (2009) Bioessays , vol.31 , pp. 1013-1025
    • Sánchez-Camacho, C.1    Bovolenta, P.2
  • 15
    • 25844431756 scopus 로고    scopus 로고
    • Touch and go: guidance cues signal to the growth cone cytoskeleton
    • Kalil K, Dent EW, (2005) Touch and go: guidance cues signal to the growth cone cytoskeleton. Curr Opin Neurobiol 15: 521-526.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 521-526
    • Kalil, K.1    Dent, E.W.2
  • 16
    • 0346120154 scopus 로고    scopus 로고
    • Regulation of growth cone actin filaments by guidance cues
    • Gallo G, Letourneau PC, (2004) Regulation of growth cone actin filaments by guidance cues. J Neurobiol 58: 92-102.
    • (2004) J Neurobiol , vol.58 , pp. 92-102
    • Gallo, G.1    Letourneau, P.C.2
  • 17
    • 0037032812 scopus 로고    scopus 로고
    • Molecular mechanisms of axon guidance
    • Dickson BJ, (2002) Molecular mechanisms of axon guidance. Science 298: 1959-1964.
    • (2002) Science , vol.298 , pp. 1959-1964
    • Dickson, B.J.1
  • 18
    • 68649124073 scopus 로고    scopus 로고
    • Semaphorin function in neural plasticity and disease
    • Pasterkamp RJ, Giger RJ, (2009) Semaphorin function in neural plasticity and disease. Curr Opin Neurobiol 19: 263-274.
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 263-274
    • Pasterkamp, R.J.1    Giger, R.J.2
  • 19
    • 0035800436 scopus 로고    scopus 로고
    • Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions
    • Marin O, Yaron A, Bagri A, Tessier-Lavigne M, Rubenstein JLR, (2001) Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions. Science 293: 872-875.
    • (2001) Science , vol.293 , pp. 872-875
    • Marin, O.1    Yaron, A.2    Bagri, A.3    Tessier-Lavigne, M.4    Rubenstein, J.L.R.5
  • 20
    • 0037065995 scopus 로고    scopus 로고
    • Knowing how to navigate: mechanisms of semaphorin signaling in the nervous system
    • Re. 1 (Review)
    • He Z, Wang KC, Koprivica V, Ming G, Song HJ, (2002) Knowing how to navigate: mechanisms of semaphorin signaling in the nervous system. Sci STKE 119: Re. 1 (Review).
    • (2002) Sci STKE , vol.119
    • He, Z.1    Wang, K.C.2    Koprivica, V.3    Ming, G.4    Song, H.J.5
  • 21
    • 58149379031 scopus 로고    scopus 로고
    • The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development
    • Ben-Zvi A, Manor O, Schachner M, Yaron A, Tessier-Lavigne M, et al. (2008) The Semaphorin receptor PlexinA3 mediates neuronal apoptosis during dorsal root ganglia development. J Neurosci 28: 12427-32.
    • (2008) J Neurosci , vol.28 , pp. 12427-12432
    • Ben-Zvi, A.1    Manor, O.2    Schachner, M.3    Yaron, A.4    Tessier-Lavigne, M.5
  • 22
    • 0038686623 scopus 로고    scopus 로고
    • Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development
    • Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, et al. (2003) Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell 5: 45-57.
    • (2003) Dev Cell , vol.5 , pp. 45-57
    • Gu, C.1    Rodriguez, E.R.2    Reimert, D.V.3    Shu, T.4    Fritzsch, B.5
  • 23
    • 1042278101 scopus 로고    scopus 로고
    • Regulation of dendritic length and branching by semaphorin 3A
    • Fenstermaker V, Chen Y, Ghosh A, Yuste R, (2004) Regulation of dendritic length and branching by semaphorin 3A. J Neurobiol 58: 403-412.
    • (2004) J Neurobiol , vol.58 , pp. 403-412
    • Fenstermaker, V.1    Chen, Y.2    Ghosh, A.3    Yuste, R.4
  • 24
    • 0036942108 scopus 로고    scopus 로고
    • Neuropilins as Semaphorin receptors: in vivo functions in neuronal cell migration and axon guidance
    • Bagri A, Tessier-Lavigne M, (2002) Neuropilins as Semaphorin receptors: in vivo functions in neuronal cell migration and axon guidance. Adv Exp Med Biol 515: 13-31.
    • (2002) Adv Exp Med Biol , vol.515 , pp. 13-31
    • Bagri, A.1    Tessier-Lavigne, M.2
  • 25
    • 0033564109 scopus 로고    scopus 로고
    • Growth cone neuropilin-1 mediates collapsin-1/Sema III facilitation of antero- and retrograde axoplasmic transport
    • Goshima Y, Hori H, Sasaki Y, Yang T, Kagoshima-Maezono M, et al. (1999) Growth cone neuropilin-1 mediates collapsin-1/Sema III facilitation of antero- and retrograde axoplasmic transport. J Neurobiol 39: 579-89.
    • (1999) J Neurobiol , vol.39 , pp. 579-589
    • Goshima, Y.1    Hori, H.2    Sasaki, Y.3    Yang, T.4    Kagoshima-Maezono, M.5
  • 26
    • 17044413281 scopus 로고    scopus 로고
    • Secreted semaphorins modulate synaptic transmission in the adult hippocampus
    • Sahay A, Kim CH, Sepkuty JP, Cho E, Huganir RL, et al. (2005) Secreted semaphorins modulate synaptic transmission in the adult hippocampus. J Neurosci 25: 3613-3620.
    • (2005) J Neurosci , vol.25 , pp. 3613-3620
    • Sahay, A.1    Kim, C.H.2    Sepkuty, J.P.3    Cho, E.4    Huganir, R.L.5
  • 27
    • 33646693622 scopus 로고    scopus 로고
    • Semaphorin3A regulates synaptic function of differentiated hippocampal neurons
    • Bouzioukh F, Daoudal G, Falk J, Debanne D, Rougon G, et al. (2006) Semaphorin3A regulates synaptic function of differentiated hippocampal neurons. Eur J Neurosci 23: 2247-2254.
    • (2006) Eur J Neurosci , vol.23 , pp. 2247-2254
    • Bouzioukh, F.1    Daoudal, G.2    Falk, J.3    Debanne, D.4    Rougon, G.5
  • 28
    • 0036932412 scopus 로고    scopus 로고
    • Solution studies and structural model of the extracellular domain of the human amyloid precursor protein
    • Gralle M, Botelho MM, Oliveira CL, Torriani I, Ferreira ST, (2002) Solution studies and structural model of the extracellular domain of the human amyloid precursor protein. Biophys J 83: 3513-3524.
    • (2002) Biophys J , vol.83 , pp. 3513-3524
    • Gralle, M.1    Botelho, M.M.2    Oliveira, C.L.3    Torriani, I.4    Ferreira, S.T.5
  • 29
    • 0030722135 scopus 로고    scopus 로고
    • The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing
    • Adams RH, Lohrum M, Klostermann A, Betz H, Püschel AW, (1997) The chemorepulsive activity of secreted semaphorins is regulated by furin-dependent proteolytic processing. EMBO J 16: 6077-6086.
    • (1997) EMBO J , vol.16 , pp. 6077-6086
    • Adams, R.H.1    Lohrum, M.2    Klostermann, A.3    Betz, H.4    Püschel, A.W.5
  • 30
    • 24744442787 scopus 로고    scopus 로고
    • Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta
    • Magdesian MH, Nery AA, Martins AH, Juliano MA, Juliano L, et al. (2005) Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta. J Biol Chem 280: 31085-31090.
    • (2005) J Biol Chem , vol.280 , pp. 31085-31090
    • Magdesian, M.H.1    Nery, A.A.2    Martins, A.H.3    Juliano, M.A.4    Juliano, L.5
  • 31
    • 44049089139 scopus 로고    scopus 로고
    • Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling
    • Magdesian MH, Carvalho MM, Mendes FA, Saraiva LM, Juliano MA, et al. (2008) Amyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling. J Biol Chem 283: 9359-9368.
    • (2008) J Biol Chem , vol.283 , pp. 9359-9368
    • Magdesian, M.H.1    Carvalho, M.M.2    Mendes, F.A.3    Saraiva, L.M.4    Juliano, M.A.5
  • 34
    • 41949097306 scopus 로고    scopus 로고
    • Müller glia factors induce survival and neuritogenesis of peripheral and central neurons
    • De Melo Reis R.A., Cabral da Silva M.C., de Mello F.G., Taylor J.S.H., et al. (2008) Müller glia factors induce survival and neuritogenesis of peripheral and central neurons. Brain Res 1205: 1-11.
    • (2008) Brain Res , vol.1205 , pp. 1-11
    • de Melo Reis, R.A.1    Cabral da Silva, M.C.2    de Mello, F.G.3    Taylor, J.S.H.4
  • 35
    • 0031458813 scopus 로고    scopus 로고
    • Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
    • Ericson J, Rashbass P, Schedl A, Brenner-Morton S, et al. (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90: 169-180.
    • (1997) Cell , vol.90 , pp. 169-180
    • Ericson, J.1    Rashbass, P.2    Schedl, A.3    Brenner-Morton, S.4
  • 37
    • 34848812223 scopus 로고    scopus 로고
    • lme4: Linear mixed-effects models using S4 classes
    • R package version 0.999375-31
    • Bates D, Maechler M, (2009) lme4: Linear mixed-effects models using S4 classes. R package version 0.999375-31.http://CRANR-projectorg/package=lme4.
    • (2009)
    • Bates, D.1    Maechler, M.2
  • 38
    • 73649141481 scopus 로고    scopus 로고
    • R Development Core Team, Vienna, R Foundation for Statistical Computing
    • R Development Core Team (2009) R: A language environment for statistical computing Vienna R Foundation for Statistical Computing.
    • (2009) R: A Language Environment for Statistical Computing
  • 39
    • 0030886550 scopus 로고    scopus 로고
    • A 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family members
    • Koppel AM, Feiner L, Kobayashi H, Raper JA, (1997) A 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family members. Neuron 19: 531-537.
    • (1997) Neuron , vol.19 , pp. 531-537
    • Koppel, A.M.1    Feiner, L.2    Kobayashi, H.3    Raper, J.A.4
  • 41
    • 77949660874 scopus 로고    scopus 로고
    • Does the term 'trophic' actually mean anti-amyloidogenic? The case of NGF
    • Calissano P, Matrone C, Amadoro G, (2010) Does the term 'trophic' actually mean anti-amyloidogenic? The case of NGF. Dev Neurobiol 70: 372-383.
    • (2010) Dev Neurobiol , vol.70 , pp. 372-383
    • Calissano, P.1    Matrone, C.2    Amadoro, G.3
  • 42
    • 0028271689 scopus 로고
    • The survival of rat cerebral cortical neurons in the presence of trophic APP peptides
    • Yamamoto K, Miyoshi T, Yae T, Karashima K, Araki H, et al. (1994) The survival of rat cerebral cortical neurons in the presence of trophic APP peptides. J Neurobiol 25: 585-594.
    • (1994) J Neurobiol , vol.25 , pp. 585-594
    • Yamamoto, K.1    Miyoshi, T.2    Yae, T.3    Karashima, K.4    Araki, H.5
  • 44
    • 46149126877 scopus 로고    scopus 로고
    • Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
    • Young-Pearse TL, Chen AC, Chang R, Marquez C, Selkoe DJ, (2008) Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Dev 23: 3-15.
    • (2008) Neural Dev , vol.23 , pp. 3-15
    • Young-Pearse, T.L.1    Chen, A.C.2    Chang, R.3    Marquez, C.4    Selkoe, D.J.5
  • 45
    • 67649366042 scopus 로고    scopus 로고
    • Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers
    • Gralle M, Botelho MG, Wouters FS, (2009) Neuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers. J Biol Chem 284: 15016-25.
    • (2009) J Biol Chem , vol.284 , pp. 15016-15025
    • Gralle, M.1    Botelho, M.G.2    Wouters, F.S.3
  • 46
    • 41549099965 scopus 로고    scopus 로고
    • Semaphorin signaling: progress made and promises ahead
    • Zhou Y, Gunput RA, Pasterkamp RJ, (2008) Semaphorin signaling: progress made and promises ahead. Trends Biochem Sci 33: 161-70.
    • (2008) Trends Biochem Sci , vol.33 , pp. 161-170
    • Zhou, Y.1    Gunput, R.A.2    Pasterkamp, R.J.3
  • 47
    • 28044451085 scopus 로고    scopus 로고
    • FARP2 triggers signals for Sema3A-mediated axonal repulsion
    • Toyofuku T, Yoshida J, Sugimoto T, Zhang H, Kumanogoh, et al. (2005) FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci 8: 1712-9.
    • (2005) Nat Neurosci , vol.8 , pp. 1712-1719
    • Toyofuku, T.1    Yoshida, J.2    Sugimoto, T.3    Zhang, H.4    Kumanogoh5
  • 48
    • 42549127846 scopus 로고    scopus 로고
    • Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system
    • Osterfield M, Egelund R, Young LM, Flanagan JG, (2008) Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. Development 135: 1189-99.
    • (2008) Development , vol.135 , pp. 1189-1199
    • Osterfield, M.1    Egelund, R.2    Young, L.M.3    Flanagan, J.G.4
  • 49
    • 33745750458 scopus 로고    scopus 로고
    • Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites
    • De Wit J, Toonen RF, Verhaagen J, Verhage M, (2006) Vesicular trafficking of semaphorin 3A is activity-dependent and differs between axons and dendrites. Traffic 7: 1060-77.
    • (2006) Traffic , vol.7 , pp. 1060-1077
    • De Wit, J.1    Toonen, R.F.2    Verhaagen, J.3    Verhage, M.4
  • 50
    • 0025056563 scopus 로고
    • Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
    • Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, et al. (1990) Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc Natl Acad Sci USA 87: 1561-1565.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1561-1565
    • Koo, E.H.1    Sisodia, S.S.2    Archer, D.R.3    Martin, L.J.4    Weidemann, A.5
  • 51
    • 33847194657 scopus 로고    scopus 로고
    • Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
    • Rusu P, Jansen A, Soba P, Kirsch J, Löwer A, et al. (2007) Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. Eur J Neurosci 25: 1079-1086.
    • (2007) Eur J Neurosci , vol.25 , pp. 1079-1086
    • Rusu, P.1    Jansen, A.2    Soba, P.3    Kirsch, J.4    Löwer, A.5
  • 52
    • 72449130946 scopus 로고    scopus 로고
    • Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity
    • Yang L, Wang Z, Wang B, Justice NJ, Zheng H, (2009) Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity. J Neurosci 29: 15660-15668.
    • (2009) J Neurosci , vol.29 , pp. 15660-15668
    • Yang, L.1    Wang, Z.2    Wang, B.3    Justice, N.J.4    Zheng, H.5
  • 53
    • 67049167155 scopus 로고    scopus 로고
    • Interaction of reelin with amyloid precursor protein promotes neurite outgrowth
    • Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, (2009) Interaction of reelin with amyloid precursor protein promotes neurite outgrowth. J Neurosci 29: 7459-7473.
    • (2009) J Neurosci , vol.29 , pp. 7459-7473
    • Hoe, H.S.1    Lee, K.J.2    Carney, R.S.3    Lee, J.4    Markova, A.5
  • 54
    • 69749115919 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
    • Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, et al. (2009) Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci 29: 10788-10801.
    • (2009) J Neurosci , vol.29 , pp. 10788-10801
    • Wang, Z.1    Wang, B.2    Yang, L.3    Guo, Q.4    Aithmitti, N.5
  • 55
    • 67649776586 scopus 로고    scopus 로고
    • The effects of amyloid precursor protein on postsynaptic composition and activity
    • Hoe HS, Fu Z, Makarova A, Lee JY, Lu C, (2009) The effects of amyloid precursor protein on postsynaptic composition and activity. J Biol Chem 284: 8495-8506.
    • (2009) J Biol Chem , vol.284 , pp. 8495-8506
    • Hoe, H.S.1    Fu, Z.2    Makarova, A.3    Lee, J.Y.4    Lu, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.