X-ray structure reveals a new class and provides insight into evolution of alkaline phosphatases

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Bihani, Subhash C ^a   Das, Amit ^a   Nilgiriwala, Kayzad S ^a   Prashar, Vishal ^a   Pirocchi, Michel ^b   Apte, Shree Kumar ^a   Ferrer, Jean Luc ^b   Hosur, Madhusoodan V ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; SERINE;

ARTICLE; BACTERIAL STRAIN; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; HYDROGEN BOND; HYDROLYSIS; MICHAELIS CONSTANT; MOLECULAR EVOLUTION; NONHUMAN; SPHINGOMONAS; AMINO ACID SEQUENCE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; KINETICS; MOLECULAR GENETICS; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); SPHINGOMONAS;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; HYDROGEN BONDING; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SPHINGOMONAS; SUBSTRATE SPECIFICITY;

EID: 79960871721     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022767     Document Type: Article

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