L1 hybridization enrichment: A method for directly accessing de novo L1 insertions in the human germline

Human Mutation

Volumn 32, Issue 8, 2011, Pages 978-988

  Freeman, Peter ^a   Macfarlane, Catriona ^a   Collier, Pamela ^a   Jeffreys, Alec J ^a   Badge, Richard M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Genome; Germline; Human; Hybridization enrichment; L1; LINE 1; Mutation rate; Retrotransposon

Indexed keywords

DNA; OLIGONUCLEOTIDE;

ARTICLE; BIOTINYLATION; CONTROLLED STUDY; DNA SCREENING; GENE AMPLIFICATION; GENE FREQUENCY; GENE INSERTION SEQUENCE; GENE LOCUS; GENE MUTATION; HAPLOIDY; HUMAN; HYBRIDIZATION; HYBRIDIZATION ENRICHMENT; LONG INTERSPERSED REPEAT; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NORMAL HUMAN; PRIORITY JOURNAL; RETROPOSON; SPERMATOGENESIS;

DNA; GENETIC LOCI; GENOME, HUMAN; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MUTAGENESIS, INSERTIONAL; NUCLEIC ACID HYBRIDIZATION; POLYMERASE CHAIN REACTION; SPERMATOZOA;

EID: 79960848374     PISSN: 10597794     EISSN: 10981004     Source Type: Journal    
DOI: 10.1002/humu.21533     Document Type: Article

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