Identification of critical CpG sites for repression of L1 transcription by DNA methylation

Gene

Volumn 189, Issue 2, 1997, Pages 227-234

  Hata, Kikumi ^a,b   Sakaki, Yoshiyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Promoter; Retrotransposon; Site specific methylation; YY1

Indexed keywords

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE REPRESSION; HUMAN; HUMAN CELL; LONG INTERSPERSED REPEAT; MUTAGENESIS; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; RETROPOSON; TRANSCRIPTION REGULATION;

FELIS CATUS;

EID: 0030940594     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00856-6     Document Type: Article

References (38)

1. Antequera, F., Boyes, J. and Bird, A. (1990) High levels of de novo methylation and altered chromatin structure at CpG island in cell lines. Cell 62, 503-514.
2. Becker, K.G., Swergold, G.D., Ozato, K. and Thayer, R.E. (1993) Binding of the ubiquitous nuclear transcription factor YY1 to cis regulatory sequence in the human LINE-1 transposable element. Hum. Mol. Genet. 2, 1697-1702.
3. Bednarik, D.P., Duckett, C., Kim, S.U., Perez, V.L., Griffis, K., Guenthner, P.C. and Folks, T.M. (1991) DNA CpG methylation inhibits binding of NF-kB proteins to the HIV-1 long terminal repeat cognate DNA motifs. New Biol. 3, 969-976.
4. Bird, A.P. (1986) CpG-rich islands and the function of DNA methylation. Nature 321, 209-213.
5. Bratthauer, G.L. and Fanning, T.G. (1992) Active LINE-1 retro-transposons in human testicular cancer. Oncogene 7, 507-510.
6. Bratthauer, G.L. and Fanning, T.G. (1993) LINE-1 retrotransposon expression in pediatric germ cell tumors. Cancer 71, 2383-2386.
7. Bratthauer, G.L., Cardiff, R.D. and Fanning, T.G. (1994) Expression of LINE-1 retrotransposons in human breast cancer. Cancer 73, 2333-2336.
8. Bryans, M., Kass, S., Seivwright, C. and Adams, R.L.P. (1992) Vector methylation inhibits transcription from the SV40 early promoter. FEBS Lett. 309, 97-102.
9. Ceder, H. (1988) DNA methylation and gene activity. Cell 53, 3-4.
10. Comb, M. and Goodman, H.M. (1990) CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucleic Acids Res. 18, 3975-3982.
11. Di Nocera, P.P. and Sakaki, Y. (1990) LINEs: a superfamily of retro-transposable ubiquitous DNA elements. Trends Genet. 6, 29-30.
12. Falzon, M. and Kuff, E.L. (1991) Binding of transcrption factor EBP-80 mediates the methylation response of an intracisternal A-particle long terminal repeat promoter. Mol. Cell. Biol. 11, 117-125.
13. Fanning, T.G. and Singer, M.F. (1987) LINE-1: a mammalian transposable element. Biochim. Biophys. Acta 910, 203-212.
14. Hattori, M., Kuhara, S., Takenaka, O. and Sakaki, Y. (1986) L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related protein. Nature 321, 625-628.
15. Hutchison III, C.A., Loeb, D.D., Shehee, W.R. and Edgell, M.H. (1989) In: Berg, D.E. and Howe, M.M. (Eds.), Mobile DNA. American Society for Microbiology, Washington, DC, pp. 593-617.
16. Iguchi-Ariga, S.M.M. and Schaffner, W. (1989) CoG methlation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. Genes Dev. 3, 612-619.
17. Jost, J.P. and Hofsteenge, J. (1992) The repressor MDBP-2 is a member of the histone H1 family that binds preferentially in vitro and in vivo to methylated nonspecific DNA sequences. Proc. Natl. Acad. Sci. USA 89, 9499-9503.
18. Kass, S.U., Goddard, J.P. and Adams, R.L.P. (1993) Inactive chromatin spreads from a focus of methylation. Mol. Cell. Biol. 13, 7372-7379.
19. Kazazian, H.H.J., Wong, C., Youssoufian, H., Scott, A.F., Phillips, D.G. and Antonarakis, S.E. (1988) Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man. Nature 332, 87-90.
20. Klempnauer, K.H. (1993) Methylation-sensitive DNA binding by v-myb and c-myb proteins. Oncogene 8, 111-115.
21. Kochanek, S., Renz, D. and Doerler, W. (1993) DNA methylation in the Alu sequences of diploid and haploid primary human cells. EMBO J. 12, 1141-1151.
22. Kurose, K., Hata, K., Hattori, M. and Sakaki, Y. (1995) RNA polymerase III dependence of the human L1 promoter and possible participation of the RNA polymerase II factor II YY1 in the RNA polymerase III transcription system. Nucleic Acids Res. 23, 3704-3709.
23. Leibold, D.M., Swergold, G.D., Singer, M.F., Thayer, R.E., Dombroski, B.A. and Fanning, T.G. (1990) Translation of LINE-1 DNA elements in vitro and in human cells. Proc. Natl. Acad. Sci. USA 80, 6990-6994.
24. 2+. Nucleic Acids Res. 24, 5354-5359.
25. Meehan, R.R., Lewis, J.D., Mckay, S., Kleiner, E.L. and Bird, A.P. (1989) Identification of a mammalian protein that binds specifically to DNA containing methylation CpGs. Cell 58, 499-507.
26. Meehan, R.R., Lewis, J.D. and Bird, A.P. (1992) Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylation DNA. Nucleic Acids Res. 20, 5085-5092.
27. Miki, Y., Nishisho, I., Horii, A., Miyoshi, Y., Utsunomiya, J., Kinzler, K.W., Vogelstein, G. and Nakamura, Y. (1992) Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res. 52, 643-645.
28. Minakami, R., Kurose, K., Etoh, K., Furuhata, Y., Hattori, M. and Sakaki, Y. (1992) Identification of an internal cis-element essential for the human L1 transcription and a nuclear factor (s) binding to the element. Nucleic Acids Res. 20, 3139-3145.
29. Morse, B., Rotherg, P.G., South, V.J., Spandorfer, J.M. and Astrin, S.M. (1988) Insertional mutagenesis of the myc locus by a LINE-1 sequence in a human breast carcinoma. Nature 333, 87-90.
30. Muiznieks, I. and Doerfler, W. (1994) The impact of 5′-CG-3′methylation on the activity of different eukaryotic promoters: a comparative study. FEBS Lett. 344, 251-254.
31. Narita, N., Nishio, H., Kitoh, Y., Ishikawa, Y., Ishikawa, Y., Minami, R., Nakamura, H. and Matsuo, M. (1993) Insertion of a 5′ truncated L1 element into the 3′ end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy. J. Clin. Invest. 91, 1862-1867.
32. Ohtani-Fujita, N., Fujita, T., Aoike, A., Osifchin, N.E. and Sakai, T. (1993) CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 8, 1063-1067.
33. Prendergast, G.C. and Ziff, B. (1991) Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science 251, 186-189.
34. Razin, A. and Riggs, A.D. (1980) DNA methylation and gene function. Science 210, 604-610.
35. Suetake, I., Tajima, S. and Asano, A. (1993) Identification of two novel mouse nuclear proteins that bind selectively to a methylation c-Myc recognizing sequence. Nucleic Acids Res. 21, 2125-2130.
36. Swergold, G.D. (1990) Identification, characterization, and cell specificity of a human LINE-1 promoter. Mol. Cell. Biol. 10, 6718-6729.
37. Thayer, R.E., Singer, M.F. and Fanning, T.G. (1993) Undermethylation of specific LINE-1 sequences in human cells producing a LINE-1-encoded protein. Gene 133, 273-277.
38. Watt, F. and Molloy, P.L. (1988) Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter. Genes Dev. 2, 1136-1143.