Computational Reverse-Engineering of a spider-venom derived peptide active against plasmodium falciparum SUB1

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Bastianelli, Giacomo ^a,b   Bouillon, Anthony ^b,c   Nguyen, Christophe ^d   Crublet, Elodie ^e   Pêtres, Stéphane ^e   Gorgette, Olivier ^b,c   Le Nguyen, Dung ^d   Barale, Jean Christophe ^b,c   Nilges, Michael ^a,b  

^a Unité de Bioinformatique Structurale   (France)

^b CNRS   (France)

^c Unité d'Immunologie Moleculaires des Parasites   (France)

^d SYSDIAG   (France)

^e INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GLUTAMINE; PEPTIDE; PROTEIN SUB1; PSALMOPEOTOXIN I; SERINE PROTEINASE; SPIDER VENOM; UNCLASSIFIED DRUG; PROTOZOAL PROTEIN; SOLVENT; SUBTILISIN;

ANTIMALARIAL ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; PLASMODIUM FALCIPARUM; PROTEIN ENGINEERING; AMINO ACID SEQUENCE; BIOCATALYSIS; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; MEROZOITE; METABOLISM; METHODOLOGY; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PROTEIN BINDING; REVERSE GENETICS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ARANEAE; PLASMODIUM FALCIPARUM; PSALMOPOEUS CAMBRIDGEI;

AMINO ACID SEQUENCE; BIOCATALYSIS; MEROZOITES; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN ENGINEERING; PROTOZOAN PROTEINS; REVERSE GENETICS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SOLVENTS; SPIDER VENOMS; SUBTILISIN;

EID: 79960820617     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021812     Document Type: Article

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