Carbon nanotubes as carriers for delivery of bioactive and therapeutic agents: An overview

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 3, Issue 3, 2011, Pages 45-52

  Mali, Nikhil ^a   Jadhav, Seema ^a   Karpe, Manisha ^a   Kadam, Vilasrao ^a  

^a BHARATI VIDYAPEETH S COLLEGE OF PHARMACY   (India)

Author keywords

Carbon nanotubes; Catalytic chemical vapour deposition; Electric arc discharge; f CNT; Laser ablation; Pristine CNTs

Indexed keywords

CARBON NANOTUBE; CISPLATIN; DEXAMETHASONE; DRUG CARRIER; FOOT AND MOUTH DISEASE VACCINE; GRAPHITE; KETOCONAZOLE; MACROGOL; METHOTREXATE; MULTIPLE WALLED CARBON NANOTUBE; NUCLEIC ACID; OLIGODEOXYNUCLEOTIDE; PACLITAXEL; RECOMBINANT ERYTHROPOIETIN; SINGLE WALLED NANOTUBE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ATOMIC FORCE MICROSCOPY; BIOCOMPATIBILITY; CHEMICAL STRUCTURE; CHROMATOGRAPHY; CYTOTOXICITY; DISPERSION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG PURIFICATION; DRUG RELEASE; DRUG UPTAKE; ENDOCYTOSIS; HUMAN; IN VIVO STUDY; MICROFILTRATION; NERVE REGENERATION; NONHUMAN; RAMAN SPECTROMETRY; REVIEW; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

EID: 79960799372     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Review

References (52)

1. Radushkevich L V, Luk'yanovich V M: Structure of the carbon produced in the thermal decomposition of carbon monoxide on an iron catalyst. Zurn. Fisic. Chim., 1952, 26, 88-95.
2. Ericson LM, Fan H, Peng H, Davis VA, Zhou W, Sulpizio J, Wang Y, Booker R, Vavro J Guthy C et al.: Macroscopic, neat, singlewalled carbon nanotube fibers. Science 2004, 305:1447-1450.
3. Milne WI, Teo KBK, Amaratunga GAJ, Legagneux P, Gangloff L, Schnell JP, Semet V, Thien Binh V, Groening O: Carbon nanotubes as field emission sources. J Mater Chem. 2004, 14:933-943.
4. Martin CR, Kohli P: The emerging field of nanotube biotechnology. Nat Rev Drug Discov 2003, 2:29-37.
5. Lin Y, Taylor S, Li H, Fernando KA, Qu L, Wang W, Gu L, Zhou B, Sun YP: Advances toward bioapplications of carbon nanotubes. J Mater Chem 2004, 14:527-541.
6. Bianco A, Kostarelos K, Partidos CD, Prato M: Biomedical applications of functionalised carbon nanotubes. Chem Commun 2005:571-577.
7. Liu Z, Sun XM, Nakayama-Ratchford N, Dai HJ. Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery. ACS Nano 2007;1(1):50-6.
8. Pantarotto D, Singh R, McCarthy D, Erhardt M, Briand JP, Prato M, et al. Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew Chem Int Ed 2004; 43(39):5242-6.
9. Dresselhaus MS, Dresselhaus G, Charlier JC, Hernandez E. Electronic, thermal and mechanical properties of carbon nanotubes. Philos Transact A Math Phys Eng Sci 2004;362: 2065-98.
10. Joselevich E. Electronic structure and chemical reactivity of carbon nanotubes: a chemist's view. Chemphyschem 2004;5:619-24.
11. S.K. Smart, A.I. Cassady, G.Q. Lu, D.J. Martin: The biocompatibility of carbon nanotubes. Carbon 44 (2006) 1034-1047.
12. Trotter H, Phillips R, Ni B, Hu Y, Sinnott SB, Mikulski PT, et al. Effect of filling on the compressibility of carbon nanotubes: predictions from molecular dynamics simulations. JNanosci Nanotechnol 2005;5:536-41.
13. Ham HT, Choi YS, Chung IJ. An explanation of dispersion states of single-walled carbon nanotubes in solvents and aqueous surfactant solutions using solubility parameters. J Colloid Interface Sci 2005;286:216-23.
14. Moore V, Strano M, Haroz E, Hauge R, Smalley R. Individually suspended single-walled carbon nanotubes in various surfactants. Nano Lett 2003;3:1379-82.
15. Vaisman L,Wagner HD, Marom G. The role of surfactants in dispersion of carbon nanotubes. Adv Colloid Interface Sci 2006;128-130:37-46.
16. Ausman K, Piner R, Lourie O, Ruoff R. Organic solvent dispersion of single-walled Carbon nanotubes: towards solutions of pristine nanotubes. J Phys Chem B 2000;104:8911-5.
17. Peng H, Alemany LB, Margrave JL, Khabashesku VN. Sidewall carboxylic acid functionalization of single-walled carbon nanotubes. J Am Chem Soc 2003;125:15174-82.
18. Zheng M, Jagota A, Semke ED, Diner BA, McLean RS, Lustig SR, et al. DNA-assisted dispersion and separation of carbon nanotubes. Nat Mater 2003;2:338-42.
19. Awasthi K, Srivastava A, Srivastava ON. Synthesis of carbon nanotubes. J Nanosci Nanotechnol 2005;5:1616-36.
20. Thess A, Lee R, Nikolaev P, Dai H, Petit P, Robert J, et al. Crystalline ropes of metallic carbon nanotubes. Science 1996;273:483-7.
21. Kleinsorge B, Golovko VB, Hofmann S, Geng J, Jefferson D, Robertson J, et al. Growth of aligned carbon nanofibres over large areas using colloidal catalysts at low temperatures. Chem Commun (Camb) 2004; 10:1416-7.
22. Jorio A, Saito R, Hafner JH, Lieber CM, Hunter M, McClure T, et al. Structural (n,m)determination of isolated single-wall carbon nanotubes by resonant Raman scattering. Phys Rev Lett 2001; 86:1118-21.
23. Zhao B, Hu H, Niyogi S, Itkis ME, Hamon MA, Bhowmik P, et al. Chromatographic purification and properties of soluble singlewalled carbon nanotubes. J Am Chem Soc 2001; 123:11673-7.
24. Martinez MT, Callejas MA, Benito AM, Maser WK, Cochet M, Andres JM, et al. Microwave single walled carbon nanotubes purification. Chem Commun (Camb) 2002; 9:1000-1.
25. Choi HC, Bae SY, Jang WS, Park J, Song HJ, Shin HJ, et al. Release of N(2) from the carbon nanotubes via high-temperature annealing. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 2005; 109:1683-8.
26. Saini RK, Chiang IW, Peng H, Smalley RE, Billups WE, Hauge RH, et al. Covalent sidewall functionalization of single wall carbon nanotubes. J Am Chem Soc 2003; 125:3617-21.
27. Itkis ME, Perea DE, Jung R, Niyogi S, Haddon RC. Comparison of analytical techniques for purity evaluation of single-walled carbon nanotubes. J Am Chem Soc 2005; 127:3439-48.
28. Odom TW, Huang JL, Lieber CM. Single-walled carbon nanotubes: from fundamental studies to new device concepts. Ann N YAcad Sci 2002; 960:203-15.
29. C.A. Dyke, J.M. Tour, Overcoming the insolubility of carbon nanotubes through high degrees of sidewall functionalization, Chem.-A Eur. J. 2004; 10:812-817.
30. M.B. Kannan Balasubramanian, Chemically functionalized carbon nanotubes, Small 2005; 1:180-192.
31. N.W. Shi Kam, T.C. Jessop, P.A. Wender, H. Dai, Nanotube molecular transporters: internalization of carbon nanotube protein conjugates into mammalian cells, J. Am. Chem. Soc. 2004; 126:6850-6851.
32. E. Smythe, Clathrin-coated vesicle formation: a paradigmfor coated-vesicle formation, Biochem. Soc. Trans. 2003; 31:736-739.
33. D. Cai, J.M. Mataraza, Z.-H. Qin, Z. Huang, J. Huang, T.C. Chiles, D. Carnahan, K. Kempa, Z. Ren, Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing, Nat Meth 2005; 2:449-454.
34. Kam N.W.S.; Liu Z.; Dai H. Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway. Angew. Chem. Int. Ed., 2006; 45:577-81.
35. CAI Shao-Yu, KONG Ji-Lie. Advance in research on carbon canotubes as diagnostic and therapeutic agents for tumour. Chinese Journal of Analytical Chemistry, 2009, 37(8): 1240-1246.
36. Liu Z, Chen K, Davis C, Sherlock S, Cao Q, Chen X, Dai H, Drug delivery with carbon nanotubes for in vivo cancer treatment, Cancer Res. 2008; 68:6652-6660.
37. Liu Z, Cai L. He, Nakayama N, Chen K, Sun X, Chen X, Dai H: In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice, Nat. Nano 2007; 2:47-52.
38. Tripisciano C, Kraemer K, Taylor A, Borowiak-Palen E: Singlewall carbon nanotubes based anticancer drug delivery system. Chemical Physics Letters 2009; 478:200-205.
39. Pantarotto D, Partidos CD, Graff R, Hoebeke J, Briand JP, Prato M, Bianco A: Synthesis, Structural characterization and immunological properties of carbon nanotubes functionalized with peptides. J Am Chem Soc 2003, 125:6160-6164.
40. Salvador-Morales C, Flahaut E, Sim E, Sloan J, Green MLH, Sim RB: Complement activation and protein adsorption by carbon nanotubes. Mol Immunol 2006; 43:193-201.
41. Kam, N.W.S.; Dai, H. Carbon nanotubes as intracellular protein transporters: generality and biological functionality. J. Am. Chem. Soc., 2005; 127:6021-6.
42. Kam, N.W.S.; Liu, Z.; Dai, H. Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. J. Am. Chem. Soc., 2005; 127:12492-3.
43. CAI Shao-Yu, KONG Ji-Lie. Advance in Research on Carbon Nanotubes as Diagnostic and Therapeutic Agents for Tumor. Chin J Anal Chem, 2009; 37(8):1240-1246.
44. McKnight TE, Melechko AV, Hensley DK, Mann DGJ, Griffin GD, Simpson ML, Tracking gene expression after DNA delivery using spatially indexed nanofiber arrays, Nano Lett. 2004; 4:1213-1219.
45. Foldvari M, Bagonluri M. Carbon nanotubes as functional excipients for nanomedicines: II. Drug delivery and biocompatibility issues. Nanomedicine: Nanotechnology, Biology, and Medicine 2008; 4;183-200.
46. Price RL, Waid MC, Haberstroh KM, Webster TJ. Selective bone cell adhesion on formulations containing carbon nanofibers, Biomaterials 2003; 24:1877-1887.
47. Mattson M, Haddon R, Rao A. Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth, J. Mol. Neurosci. 2000; 14:175-182.
48. Jan E, Kotov EA. Successful differentiation of mouse neural stem cells on layer by layer assembled single-walled carbon nanotube composite, Nano Lett. 2007; 7:1123-1128.
49. Shvedova AA et al. Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells, J. Toxicol. Environ. Health, Part A 2003; 66: 1909-1926.
50. Sato Y et al. Influence of length on cytotoxicity of multi-walled carbon nanotubes against human acute monocytic leukemia cell THP-1 in vitro and subcutaneous tissue of rats in vivo, Mol. BioSyst. 2005; 1:176-183.
51. Lam CW, James JT, McCluskey R, Hunter RL. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intractracheal instillation, Toxicol. Sci. 2004; 77:126-134.
52. Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GAM, Webb TR. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats, Toxicol. Sci. 2004; 77:117-125.