7TM-Cadherins: Developmental roles and future challenges

Advances in Experimental Medicine and Biology

Volumn 706, Issue , 2010, Pages 14-36

  Formstone, Caroline J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CADHERIN; CADHERIN EPIDERMAL GROWRH FACTOR LAMININ G LIKE SEVEN PASS RECEPTOR; CADHERIN EPIDERMAL GROWRH FACTOR LAMININ G LIKE SEVEN PASS RECEPTOR 1; CADHERIN EPIDERMAL GROWRH FACTOR LAMININ G LIKE SEVEN PASS RECEPTOR 2; CADHERIN EPIDERMAL GROWRH FACTOR LAMININ G LIKE SEVEN PASS RECEPTOR 3; DISHEVELLED 1; DISHEVELLED 2; DISHEVELLED 3; DISHEVELLED PROTEIN; EPIDERMAL GROWTH FACTOR; FLAMINGO 1 PROTEIN; FLAMINGO 1A PROTEIN; FLAMINGO 1B PROTEIN; FLAMINGO 2 PROTEIN; FLAMINGO 3 PROTEIN; FRIZZLED PROTEIN; FRIZZLED PROTEIN 3; FRIZZLED PROTEIN 6; G PROTEIN COUPLED RECEPTOR; LAMININ; NOTCH RECEPTOR; SCRIBBLED PROTEIN; UNCLASSIFIED DRUG; WNT11 PROTEIN; WNT5A PROTEIN;

ARTICLE; C FLAMINGO1 GENE; C FLAMINGO3 GENE; CELL MIGRATION; CELL MOTION; CELL POLARITY; CELSR1 GENE; CELSR2 GENE; CELSR3 GENE; CENTRAL NERVOUS SYSTEM; DENDRITE; DROSOPHILA; EMBRYO DEVELOPMENT; EPIDERMIS; EYE DEVELOPMENT; GASTRULATION; GENE; HAIR CELL; HAIR FOLLICLE; INNER EAR; MORPHOGENESIS; MOTONEURON; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NEURULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR CELL; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; SYNAPTOGENESIS;

ANIMALS; BIOLOGICAL EVOLUTION; CADHERINS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MORPHOGENESIS; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN ISOFORMS;

VERTEBRATA;

EID: 79960777841     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-7913-1_2     Document Type: Article

References (122)

1. Hulpiau P, van Roy F. Molecular evolution of the cadherin superfamily. Int J Biochem Cell Biol 2009; 41:349-369.
2. Yagi T, Takeichi M. Cadherin superfamily genes: Functions, genomic organization and neurologic diversity. Genes Dev 2000; 14:1169-1180. (Pubitemid 30327498)
3. Davis CG. The many faces of epidermal growth factor repeats. New Biol 1990; 2:410-419. (Pubitemid 20235652)
4. Timpl R, Tisi D, Talts JF et al. Structure and function of laminin LG modules Matrix Biol 2000; 19:309-317. (Pubitemid 30665654)
5. Oda H, Tsukita S. Nonchordate classic cadherins have a structurally and functionally unique domain that is absent from chordate classic cadherins. Dev Biol 1999; 216:406-422.
6. Hotta K, Takahashi H, Ueno N et al. A genome-wide survey of the genes for planar polarity signalling or convergent-extension-related genes in Ciona intestinalis and phylogenetic comparisons of evolutionary conserved signalling components. Gene 2003; 317:165-185. (Pubitemid 37356932)
7. Hadjantonakis A-K, Formstone CJ, Little PFR. mCelsr1 is an evolutionarily conserved seven-pass transmembrane receptor and is expressed during mouse embryonic development. Mech Dev 1998; 78:91-95. (Pubitemid 28566215)
8. Hill E, Broadbent ID, Chothia C et al. Cadherin Superfamily Proteins in Caenorhabditis elegans and Drosophila melanogaster. J Mol Biol 2001; 305:1011-1024. (Pubitemid 33027739)
9. Pettitt J. The cadherin superfamily (December 29,2005). In: Moerman DG, Kramer JM, eds. The C. elegans Research Community, WormBook. Online review.
10. Hadjantonakis A-K, Sheward WJ, Harmar AJ et al. Celsrl, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter. Genomics 1997; 45:97-104. (Pubitemid 27449388)
11. Usui T, Shima Y, Shimada Y et al. Flamingo, a seven-pass transmembrane cadherin, regulates Planar Cell Polarity under the control of Frizzled. Cell 1999; 98:585-595. (Pubitemid 29418950)
12. Chae J, Kim MJ, Goo JH et al. The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development 1999; 126:5421-5429. (Pubitemid 30015934)
13. Nakayama N, Nakajima D, Nagase T et al. Identification of high-molecular- weight proteins with multiple EGF-like motifs by motif-trap screening. Genomics 1998; 51:27-34. (Pubitemid 28373370)
14. Formstone CJ, Little PFR. The flamingo-related Celsr family (Celsrl-3) genes exhibit distinct patterns of expression during embryonic development. Mech Dev 2001; 109:91-94. (Pubitemid 33035919)
15. Shima Y, Copeland NG, Gilbert DJ et al. Differential expression of the seven-pass transmembrane cadherin genes Celsr1 -3 and distribution of the Celsr2 protein during mouse development. Dev Dyn 2002; 223:321-332. (Pubitemid 34203078)
16. TissirF, De-Backer O, Goffinet AM et al. Developmental expression profiles of Celsr (flamingo) genes in the mouse. Mech Dev 2002; 112:157-160. (Pubitemid 34163229)
17. Formstone CJ, Mason I. Expression of the Celsr/flamingo homologue, c-fmil, in the early avian embryo indicates a conserved role in neural tube closure and additional roles in asymmetry and somitogenesis. Dev Dyn 2005; 232:408-413. (Pubitemid 40129795)
18. Davies A, Formstone C, Mason I et al. Planar polarity of hair cells in the chick inner ear is correlated with polarized distribution of c-flamingo-1 protein. Dev Dyn 2005; 233:998-1005. (Pubitemid 40853475)
19. Formstone CJ, Mason I. Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Dev Biol 2005; 282:320-335. (Pubitemid 40799324)
20. Wada H, Tanaka H, Nakayama S et al. Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain. Development 2006; 133:4749-4759. (Pubitemid 46063087)
21. Morgan R, El-Kadi AM, Theokli C. Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis. Int J Dev Biol 2003; 47:245-252. (Pubitemid 36604845)
22. Crompton LA, Du Roure C, Rodriguez TA. Early embryonic expression patterns of the mouse flamingo and prickle homologues. Dev Dyn 2007; 236:3137-3143. (Pubitemid 350175010)
23. Beall SA, Boekelheide K, Johnson KA. Hybrid GPCR/Cadherin (Celsr) Proteins in Rat Testis Are Expressed With Cell Type Specificity and Exhibit Differential Sertoli Cell-Germ Cell Adhesion Activity. J Androl 2005; 26:529-538. (Pubitemid 40847866)
24. Gao F-B, Kohwi M, Brenman JE et al. Control of Dendritic field formation in Drosophila: The roles of Flamingo and competition between homologous neurons. Neuron 2000; 28:91-101.
25. Lee RC, Clandinin TR, Lee CH et al. The protocadherin Flamingo is required for axon target selection in the Drosophila visual system. Nat Neuroscience 2003; 6:57-563.
26. Senti K-A, Usui T, Boucke K et al. Flamingo Regulates R8 Axon-Axon and Axon-target Interactions in the Drosophila visual system. Curr Biol 2003; 13:828-832. (Pubitemid 36573250)
27. Lawrence PA, Shelton PMJ. The determination of polarity in the developing insect retina. J Embryol Exp Morphol 1975; 33:471-486.
28. Adler PN. Planar signalling and morphogenesis in Drosophila. Dev Cell 2002; 2:525-535.
29. Strutt H, Strutt D. Long-range coordination of planar polarity in Drosophila. Bioessays 2005; 27:1218-1227. (Pubitemid 43076164)
30. Strutt D. The planar polarity pathway. Curr Biol 2008; 18:R898-902.
31. Lawrence PA, Struhl G, Casal J. Planar Cell Polarity: One or two pathways? Nat Reviews Genet 2007; 8:555-562.
32. Ma D, Amonlirdviman K, Raffard RL et al. Cell Packing influences planar cell polarity signalling. PNAS 2008; 105:18800-18806.
33. Simons M, Mlodzik M. Planar Cell Polarity signalling: From fly development to human disease. Ann Rev Genet 2008; 42:25.1-25.24.
34. Wang Y, Guo N, Nathans J. The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci 2006; 26:2147-2156 (Pubitemid 44699023)
35. Guo N, Hawkins C, Nathans J. Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci USA 2006; 101:9277-9281.
36. Wallingford JB, Harland RM. Neural tube closure requires Dishevelled-dependent convergent extension of the midline. Development 2002; 129:5815-5825. (Pubitemid 36054623)
37. Hamblet NS, Lijam N, Ruiz-Lozano P et al. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development 2002; 129:5827-5838. (Pubitemid 36054624)
38. Wang J, Mark S, Zhang X et al. Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet 2005; 37:980-985. (Pubitemid 43086156)
39. Wang J, Hamblet NS, Mark S et al. Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development 2006; 133:1767-1778. (Pubitemid 43810983)
40. Etheridge SL, Ray S, Li S et al. Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea and neural tube development. PLoS Genet 2008; 4:el000259.
41. Park TJ, Mitchell BJ, Abitua PB et al. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat Genet 2008; 40:871-879. (Pubitemid 351913644)
42. Cirone P, Lin S, Griesbach HL et al. A role for planar cell polarity signaling in angiogenesis. Angiogenesis 2008; 11:347-360.
43. Darken RS, Scola AM, Rakeman AS et al. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J 2002; 21:976-985. (Pubitemid 34206170)
44. Jessen JR, Topczewski J, Bingham S et al. Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements. Nat Cell Biol 2002; 4:610-615.
45. Voiculescu O, Bertocchini F, Wolpert L et al. The amniote primitive streak is defined by epithelial cell interaction before gastrulation. Nature 2007; 449:1049-1052. (Pubitemid 350014595)
46. Murdoch JN, Doudney K, Paternotte C et al. Severe neural tube defects in the loop-tail mouse result from mutation of Lppl, a novel gene involved in floor plate specification. Hum Mol Gen 2001; 10:2593-2601. (Pubitemid 33095009)
47. Montcouquiol M, Rachel RA, Lanford PJ et al. Identification of Vangl2 and Scrbl as planar polarity genes in mammals. Nature 2003; 423:173-177. (Pubitemid 36569540)
48. López-Schier H, Hudspeth AJ. A two-step mechanism underlies the planar polarization of regenerating sensory hair cells. Proc Natl Acad Sci USA 2006; 103:18615-18620. (Pubitemid 44913459)
49. Devenport D, Fuchs E. Planar polarisation in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol 2008; 10:1257-1289.
50. Phillips HM, Murdoch JN, Chaudhry B et al. Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract. Circ Res 2005; 96:292-299. (Pubitemid 40279903)
51. Bingham SM, Higashijima S, Okamoto H et al. The zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Dev Biol 2002; 242:149-160. (Pubitemid 34163977)
52. Ross AJ, May-Simera H, Eichers ER et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet 2005; 37:1135-1140. (Pubitemid 41486669)
53. Lake BB, Sokol SY. Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain. J Cell Biol 2009; 185:59-66.
54. Veeman MT, Slusarski DC, Kaykas A et al. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr Biol 2003; 13:680-685. (Pubitemid 36453318)
55. Takeuchi M, Nakabayashi J, Sakaguchi T et al. The prickle-related gene in vertebrates is essential for gastrulation cell movements. Curr Biol 2003; 13:674-679. (Pubitemid 36453317)
56. Carreira-Barbosa F, Concha M, Takeuchi M et al. Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development 2003; 130:4037-4046. (Pubitemid 37063422)
57. Wallingford JB, Vogeli KM, Harland RM. Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway. Int J Dev Biol 2001; 45:225-227.
58. Kilian B, Mansukoski H, Barbosa FC et al. The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mech Dev 2003; 120:467-476. (Pubitemid 36379262)
59. Qian D, Jones C, Rzadzinska A et al. Wnt5a functions in planar cell polarity regulation in mice. Dev Biol 2007; 306:121-133. (Pubitemid 46823929)
60. Cervantes S, Yamaguchi TP, Hebrok M. Wnt5a is essential for intestinal elongation in mice. Dev Biol 2009; 326:285-294.
61. Vivancos V, Chen P, Spassky N et al. Wnt activity guides facial branchiomotor neuron migration and involves the PCP pathway and JNK and ROCK kinases. Neural Dev 2009; Epub ahead of print.
62. Tada M, Smith JC. Xwnt1 1 is a target of Xenopus brachyury: Regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. Development 2000; 127:2227-2238. (Pubitemid 30386686)
63. Ulrich F, Concha ML, Heid PJ et al. Slb/Wnt1 1 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development 2003; 130:5375-5384. (Pubitemid 37484006)
64. Hardy KM, Garriock RJ, Yatskievych TA et al. Noncanonical Wnt signaling through Wnt5a/b and a novel Wnt1 1 gene, Wnt1 1b, regulates cell migration during avian gastrulation. Dev Biol 2008; 320:391-401.
65. De Calisto J, Araya C, Marchant L et al. Essential role of noncanonical Wnt signalling in neural crest migration. Development 2005; 132:2587-2597. (Pubitemid 40883257)
66. Gros J, Serralbo O, Marcelle C. WNT11 acts as a directional cue to organize the elongation of early muscle fibres. Nature 2009; 457:589-593.
67. Murdoch JN, Henderson DJ, Doudney K et al. Disruption of Scribble (Scrb1) causes severe neural tube defects in the circletail mouse. Hum Mol Genet 2003; 12:87-98. (Pubitemid 36124445)
68. Phillips HM, Rhee HJ, Murdoch JN et al. Disruption of planar cell polarity signalling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization. Circ Res 2007; 101:137-145. (Pubitemid 47196581)
69. Wada H, Iwasaki M, Sato T et al. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development 2005; 132:2273-2285. (Pubitemid 40872798)
70. Lu X, Borchers AD, Jolicoeur C et al. PTK-7/CCK-4 is anovel regulator of planar cell polarity in vertebrates. Nature 2004; 430:93-98. (Pubitemid 38915231)
71. Shnitsar I, Borchers A. PTK7 recruits dsh to regulate neural crest migration. Development 2008; 135:4015-4024.
72. Montcouquiol M, Sans N, Huss D et al. Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J Neurosci 2006; 26:5265-5275. (Pubitemid 44315309)
73. Thorpe CJ, Schlesinger A, Bowerman B. Wnt signalling in C.elegans: Regulating repressors and polarising the cytoskeleton. Trends Cell Biol 2000; 10:10-17. (Pubitemid 30017861)
74. Yamamoto S, Nishimura O, Misaki K et al. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signalling by stabilising the Wnt-receptor complex. Dev Cell 2008; 15:23-26.
75. Lawrence PA, Casal J, Struhl G Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen. Development 2002; 129:2749-2760. (Pubitemid 34874257)
76. Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 2000; 403:676-680. (Pubitemid 30104011)
77. Gubb D, Garcia-Bellido A. A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. J Embryol Exp Morphol 1982; 68:37-57. (Pubitemid 12142746)
78. Adler PN, Krasnow RE, Liu J. Tissue polarity points from cells that have higher Frizzled levels towards cells that have lower Frizzled levels. Curr Biol 1997; 7:940-949. (Pubitemid 28017071)
79. Widelitz R. Wnt signaling through canonical and noncanonical pathways: Recent progress. Growth Factors 2005; 23:111-116. (Pubitemid 43203058)
80. Grigoryan T, Wend P, Klaus A et al. Deciphering the function of canonical Wnt signals in development and disease: Conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 2008; 22:2308-2341.
81. Gordon MD, Nusse R. Wnt signaling: Multiple pathways, multiple receptors and multiple transcription factors. J Biol Chem 2006; 281:22429-22433.
82. Tree DR, Shulman JM, Rousset R et al. Prickle mediates feedback amplification to generate asymmetric planar cell polarity signalling. Cell 2002; 109:371-381. (Pubitemid 34606879)
83. Amonlirdviman K, Khare NA, Tree DR et al. Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science 2005; 307:423-426. (Pubitemid 40139987)
84. Lawrence PA, Casal J, Struhl G. Cell interactions and planar polarity in the abdominal epidermis of Drosophila. Development 2004; 131:4651-4664. (Pubitemid 39433453)
85. Das G, Reynolds-Kenneally J, Mlodzik M. The Atypical Cadherin Flamingo links Frizzled and Notch Signalling in Planar Polarity establishment in the Drosophila eye. Dev Cell 2002; 2:655-666. (Pubitemid 34538145)
86. Lu B, Usui T, Uemura T et al. Flamingo controls planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila. Curr Biol 1999; 9:1247-1250. (Pubitemid 29527150)
87. Vinson CR, Adler PN. Directional noncell autonomy and the transmission of polarity information by the frizzled gene of Drosophila. Nature 1987; 329:549-551. (Pubitemid 17131095)
88. Adler PN, Taylor J, Charlton J. The domineering non-autonomy of frizzled and van Gogh clones in the Drosophila wing is a consequence of a disruption in local signalling. Mech Dev 2000; 96:197-207.
89. Shimada Y, Usui T, Yanagawa S et al. Asymmetric colocalisation of Flamingo, a seven-pass transmembrane cadherin and Dishevelled in planar cell polarisation. Curr Biol 2001; 11:859-863. (Pubitemid 32532811)
90. Strutt D. Asymmetric localisation of Frizzled and the establishment of cell polarity in the Drosophila wing. Mol Cell 2001; 7:367-375. (Pubitemid 32206504)
91. Chen WS, Antic D, Matis M et al. Asymmetric homotypic interactions of the atypical cadherin Flamingo mediate intercellular polarity signalling. Cell 2008; 133:1093-1105. (Pubitemid 351787749)
92. Strutt H, Strutt D. Differential stability of Flamingo protein complexes underlies the establishment of planar polarity in Drosophila. Curr Biol 2008; 18:1555-1564.
93. Wu J, Mlodzik M. The Frizzled extracellular domain is a ligand for Van Gogh/Stbm during non-autonomous planar cell polarity signalling. Dev Cell 2008; 15:462-469.
94. Lawrence PA, Struhl G, Casal J. Planar Cell polarity: A bridge too far? Curr. Biol 2008; 18:R959-960.
95. Mlodzik M. Planar polarity in the Drosophila eye: A multifaceted view of signaling specificity and cross-talk. EMBO J 1999; 18:6873-6879. (Pubitemid 30000440)
96. Curtin JA, Quint E, Tsipouri V et al. Mutation in Celsr1 disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse. Curr Biol 2003; 13:1129-1133. (Pubitemid 36815261)
97. Tissir F, Bar I, Jossin Y et al. Protocadherin Celsr3 is crucial in axonal tract development. Nat Neuro 2005; 8:451-457. (Pubitemid 41007562)
98. Zhou L, Bar I, Tissir F et al. Early Forebrain Wiring: Genetic dissection using conditional mutant mice. Science 2008; 320:946-950.
99. Ying G, Wu S, Hou R et al. Protocadherin Celsr3 is required for interneuron migration in the mouse forebrain. Mol Cell Biol 2009; Epub ahead of print.
100. Warga RM, Kimmel CB. Cell movements during epiboly and gastrulation in zebrafish. Development 1990; 108:569-580.
101. Solnica-Krezel L. Conserved patterns of cell movements during vertebrate gastrulation. Curr Biol 2005; 15:R213-228. (Pubitemid 40413386)
102. Carreira-Barbosa F, Kajita M, Morel V et al. Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development 2009; 136:383-392.
103. Ybot-Gonzalez P, Savery D, Gerrelli D et al. Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure. Development 2007; 134:789-799. (Pubitemid 46437920)
104. Ciruna B, Jenny A, Lee D et al. Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 2006; 439:220-224. (Pubitemid 43083145)
105. Deans MR, Antic D, Suyama K et al. Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epitheliain the inner ear. JNeurosci 2007; 27:3139-3147. (Pubitemid 46474123)
106. Ravni A, Yibo Q, Goffinet A et al. Planar Cell Polarity Cadherin Celsrl regulates skin hair patterning in the mouse. J Invest Derm 2009; Epub ahead of print.
107. Shima Y, Kengaku M, Hirano T et al. Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin. Dev Cell 2004; 7:205-216. (Pubitemid 39145025)
108. Shima Y, Kawaguchi S-y, Kosaka K et al. Opposing roles in neurite growth control by two seven-pass transmembrane cadherins. Nat Neuroscience 2007; 10:963-969. (Pubitemid 47185201)
109. Tissir F, Goffinet AM. Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neuro 2006; 23:5976-5607.
110. Chandrasekhar A. Turning heads: Development of vertebrate branchiomotor neurons. Dev Dyn 2004; 229:143-161. (Pubitemid 38036831)
111. Chen P-L, Clandinin TR. The cadherin Flamingo mediates level-dependent interactions that guide photoreceptor target choice in Drosophila. Neuron 2008; 58:26-33. (Pubitemid 351467025)
112. Steinel MC, Whitington PM. The atypical cadherin Flamingo is required for sensory axon advance beyond intermediate target cells. Dev Biol 2009:327:447-457.
113. Zhou L, Qu Y, Tissir F et al. Role of the Atypical Cadherin Celsr3 during Development of the Internal Capsule. Cereb Cortex 2009; Epub ahead of print.
114. Sweeney NT, Li W, Gao F-B. Genetic manipulation of single neurons in vivo reveals specific roles of Flamingo in neuronal morphogenesis. Dev Biol 2002; 247:76-88. (Pubitemid 34681166)
115. Kimura H, Usui T, Tsubouchi A et al. Potential dual molecular interaction of the Drosophila 7-pass transmembrane cadherin Flamingo in dendritic morphogenesis. J Cell Sci 2006; 119:1118-1129.
116. Volynski KE, Silva JP, Lelianova VG et al. Latrophilin fragments behave as independent proteins that associate and signal on binding LTX (N4C). EMBO J 2004; 23:4423-4433. (Pubitemid 39601967)
117. Silva JP, Lelianova V, Hopkins C et al. Functional cross-interaction of the fragments produced by the cleavage of distinct adhesion G-protein-coupled receptors. J Biol Chem 2009; 284:6495-6506.
118. Witzel S, Zimy anin V, Carreira-Barbosa F et al. Wnt 11 controls cell contact persistence by local accumulation of Frizzled7 at the plasma membrane. J Cell Biol 2006; 175:791-802. (Pubitemid 44878511)
119. Wasserscheid I, Thomas U, Knust E. Isoform-specific interaction of Flamingo/Starry Night with excess Bazooka affects Planar Cell Polarity in the Drosophila wing. Dev Dyn 2007; 236:1064-1071. (Pubitemid 46641347)
120. Ye B, Jan YN. The cadherin superfamily and dendrite development. Trends Cell Biol 2005; 15:65-67.
121. Reuter JE, Nardine TM, Penton A et al. A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis. Development 2003; 130:1203-1213. (Pubitemid 36395701)
122. Sakai T, Oshima A, Nozaki Y et al. Changes in density of calcium-binding-protein-immunoreactive GABAergic neurons in prefrontal cortex in schizophrenia and bipolar disorder.Neuropathology 2008; 28:143-150. (Pubitemid 351441698)