Structure and function of laminin LG modules

Matrix Biology

Volumn 19, Issue 4, 2000, Pages 309-317

  Timpl, Rupert ^a   Tisi, Dominic ^b   Talts, Jan F ^a   Andac, Zeynep ^a   Sasaki, Takako ^a   Hohenester, Erhard ^b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Extracellular and receptor proteins; Laminin G domain; Tandem array

Indexed keywords

AGRIN; CARBOHYDRATE; CELL RECEPTOR; DYSTROGLYCAN; EPITOPE; HEPARIN; INTEGRIN; LAMININ; NEUREXIN; SULFATIDE;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; CALCIUM BINDING; CRYSTAL STRUCTURE; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; RECEPTOR BINDING; REVIEW; SITE DIRECTED MUTAGENESIS;

EID: 0034254083     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(00)00072-X     Document Type: Short Survey

References (42)

1. Andac Z., Sasaki T., Mann K., Brancaccio A., Deutzmann R., Timpl R. Analysis of heparin, α-dystroglycan and sulfatide binding to the G domain of laminin α1 chain by site-directed mutagenesis. J. Mol. Biol. 287:1999;253-264.
2. Aumailley M., Gimond C., Rousselle P. Integrin-mediated cellular interactions with laminins. Ekblom P., Timpl R. The Laminins. 1996;127-158 Harwood Academic Publisher, Reading.
3. Ayad S., Boot-Handford R.P., Humphries M.J., Kadler K.E., Shuttleworth C.A. The Extracellular Matrix Facts Book. 2nd:1999;Academic Press, San Diego.
4. Beck K., Hunter I., Engel J. Structure and function of laminin: anatomy of a multidomain glycoprotein. FASEB J. 4:1990;148-160.
5. Beckmann G., Hanke J., Bork P., Reich J.G. Merging extracellular domains: fold prediction for laminin G-like and aminoterminal thrombospondin-like modules based on homology to pentraxins. J. Mol. Biol. 275:1998;725-730.
6. Bork P., Downing A.K., Kieffer B., Campbell I.D. Structure and distribution of modules in extracellular proteins. Q. Rev. Biophys. 29:1996;119-167.
7. Bruch M., Landwehr R., Engel J. Dissection of laminin by cathepsin G into its long-arm and short-arm structures and localization of regions involved in calcium dependent stabilization and self association. Eur. J. Biochem. 185:1989;271-279.
8. Burgeson R.E. Ekblom P., Timpl R. The laminins: Laminins in Epidermal Structures. 1996;65-96 Harwood Academic Publisher, Reading.
9. Deutzmann R., Aumailley M., Wiedemann H., Pysny W., Timpl R., Edgar D. Cell adhesion, spreading and neurite stimulation by laminin fragment E8 depends on maintenance of secondary and tertiary structure in its rod and globular domain. Eur. J. Biochem. 191:1990;513-522.
10. Engel J., Bozik D. Modules in ECM and adhesion molecules. Kreis T., Vale R. Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins. 1999;344-351 Oxford University Press.
11. Esnouf R.M. An extensively modified version of MOLSCRIPT which includes greatly enhanced colouring facilities. J. Mol. Graph. 15:1997;132-134.
12. Friedrich M.V.K., Göhring W., Mörgelin M., Brancaccio A., David G., Timpl R. Structural basis of glycosaminoglycan modification and of heterotypic interactions of perlecan domain V. J. Mol. Biol. 294:1999;259-270.
13. Gesemann M., Cavalli V., Denzer A.J., Brancaccio A., Schumacher B., Rüegg M.A. Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor. Neuron. 16:1996;755-767.
14. Grishkovskaya I., Avvakumov G.V., Sklenar G., Dales D., Hammond G.L., Muller Y.A. Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain. EMBO J. 19:2000;504-512.
15. Hall H., Vorherr T., Schachner M. Characterization of a 21 amino acid peptide sequence of the laminin G2 domain that is involved in HNK-1 carbohydrate binding and cell adhesion. Glycobiol. 5:1995;435-441.
16. Hall H., Deutzmann R., Timpl R., Vaughan L., Schmitz B., Schachner M. HNK-1 carbohydrate-mediated cell adhesion to laminin-1 is different from heparin-mediated and sulfatide-mediated cell adhesion. Eur. J. Biochem. 246:1997;233-242.
17. Henry M.D., Campbell K.P. Dystroglycan inside and out. Curr. Opin. Cell Biol. 11:1999;602-607.
18. Hohenester E., Tisi D., Talts J.F., Timpl R. The crystal structure of a laminin G-like module reveals the molecular basis of α-dystroglycan binding to laminins, perlecan and agrin. Mol. Cell. 4:1999;783-792.
19. Joseph D.R., Baker M.E. Sex hormone-binding globulin, androgen-binding protein, and vitamin K-dependent protein S are homologous to laminin A, merosin and Drosophila crumbs protein. FASEB J. 6:1992;2477-2481.
20. Kalb E., Engel J. Binding and calcium-induced aggregation of laminin onto lipid bilayers. J. Biol. Chem. 266:1991;19047-19052.
21. Kraulis P.J. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:1991;946-950.
22. Merritt E.A., Murphy M.E.P. Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr. D50:1994;869-873.
23. Nicholls A., Sharp K.A., Honig B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins. 11:1991;281-296.
24. Nomizu M., Kim W.H., Yamamura K. et al. Identification of cell binding sites in the laminin α1 chain carboxy-terminal globular domain by systematic screening of synthetic peptides. J. Biol. Chem. 270:1995;20583-20590.
25. Ott U., Odermatt E., Engel J., Furthmayr H., Timpl R. Protease resistance and conformation of laminin. Eur. J. Biochem. 123:1982;63-72.
26. Pan T.C., Kluge M., Zhang R.Z., Mayer U., Timpl R., Chu M.L. Sequence of extracellular mouse protein BM-90/fibulin and its calcium-dependent binding to other basement membrane ligands. Eur. J. Biochem. 215:1993;733-740.
27. Patthy L. A family of laminin-related proteins controlling ectodermal differentiation in Drosophila. FEBS Lett. 298:1992;182-184.
28. Rambukkana A., Salzer J.L., Yurchenco P.D., Tuomanen E.I. Neural targeting of mycobacterium leprae mediated by the G domain of laminin-α2 chain. Cell. 88:1997;811-821.
29. Rambukkana A., Yamada H., Zanazzi G. et al. Role of α-dystroglycan as a Schwann cell receptor for mycobacterium leprae. Science. 282:1998;2076-2079.
30. Rudenko G., Nguyen T., Chelliah Y., Südhof T.C., Deisenhofer J. The structure of the ligand-binding domain of neurexin Iβ: regulation of LNS domain function by alternative splicing. Cell. 99:1999;93-101.
31. Sasaki T., Costell M., Mann K., Timpl R. Inhibition of glycosaminoglycan modification of perlecan domain I by site-directed mutagenesis changes protease sensitivity and laminin-1 binding activity. FEBS Lett. 435:1998;169-172.
32. Sasaki M., Kleinman H.K., Huber H., Deutzmann R., Yamada Y. Laminin, a multidomain protein: the A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains. J. Biol. Chem. 263:1988;16536-16544.
33. Sasaki T., Timpl R. Laminins. Kreis T., Vale R. Guidebook to the Extracellular Matrix, Anchor and Adhesion Proteins. 1999;434-443 Oxford University Press.
34. Shimizu H., Hosokawa H., Ninomiya H., Miner J.H., Masaki T. Adhesion of cultured bovine aortic endothelial cells to laminin-1 mediated by dystroglycan. J. Biol. Chem. 274:1999;11995-12000.
35. Shimoji Y., Ng V., Matsumara K., Fischetti V.A., Rambukkana A. A 21-kDa surface protein of Mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion. Proc. Natl. Acad. Sci. USA. 96:1999;9857-9862.
36. Sung U., O'Rear J.J., Yurchenco P.D. Cell and heparin binding in the distal long arm of laminin: identification of active and cryptic sites with recombinant and hybrid glycoprotein. J. Cell Biol. 123:1993;1255-1268.
37. Talts J.F., Mann K., Yamada Y., Timpl R. Structural analysis and proteolytic processing of recombinant G domain of mouse laminin α2 chain. FEBS Lett. 426:1998;71-76.
38. Talts J.F., Timpl R. Mutation of a basic sequence in the laminin α2LG3 module leads to lack of proteolytic processing and has different effects on β1 integrin-mediated cell adhesion and α-dystroglycan binding. FEBS Lett. 458:1999;319-323.
39. Talts J.F., Andac Z., Göhring W., Brancaccio A., Timpl R. Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α-dystroglycan and several extracellular matrix proteins. EMBO J. 18:1999;863-870.
40. Taraboletti G., Rao C.N., Krutzsch H.C., Liotta L.A., Roberts D.D. Sulfatide-binding domain of the laminin A chain. J. Biol. Chem. 265:1990;12253-12258.
41. Tisi D., Talts J.F., Timpl R., Hohenester E. Structure of the C-terminal laminin G-like domain pair of the laminin (2 chain harbouring binding sites for (-dystroglycan and heparin. EMBO J. 19:2000;1432-1440.
42. Yurchenco P.D., Sung U., Ward M.D., Yamada Y., O'Rear J.J. Recombinant laminin G domain mediates myoblast adhesion and heparin binding. J. Biol. Chem. 268:1993;8356-8365.