Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract

Circulation Research

Volumn 96, Issue 3, 2005, Pages 292-299

  Phillips, Helen M ^a   Murdoch, Jennifer N ^b   Chaudhry, Bill ^a   Copp, Andrew J ^c   Henderson, Deborah J ^a,d  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d INSTITUTE OF HUMAN GENETICS   (United Kingdom)

Author keywords

Cardiac muscle; Congenital heart defects; Development; Genes; Mouse mutant

Indexed keywords

ACTIN; PROTEIN; PROTEIN ROCK1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CELL MIGRATION; CELL MOTION; CELL POLARITY; CONTROLLED STUDY; CYTOSKELETON; FETUS; GENE; GENE ACTIVITY; HEART; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; INHIBITION KINETICS; MEDIATOR; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROXIMAL OUTFLOW TRACT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STRESS FIBER; TISSUE; VANGL2 GENE; WILD TYPE;

ANIMALS; CARDIOMYOPATHIES; CELL MOVEMENT; CELL POLARITY; EMBRYONIC INDUCTION; HEART; HEART DEFECTS, CONGENITAL; HEART SEPTAL DEFECTS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED STRAINS; MUTATION; MYOCARDIUM; NERVE TISSUE PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; VENTRICULAR REMODELING; WNT PROTEINS;

EID: 14044263538     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000154912.08695.88     Document Type: Article

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