Protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells

Canadian Journal of Physiology and Pharmacology

Volumn 89, Issue 6, 2011, Pages 445-453

  Chen, Tao ^a   Guo, Zai pei ^a   Jiao, Xiao yan ^a   Zhang, Yu hong ^a   Li, Jing yi ^a   Liu, Hong jie ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Cell viability; Human umbilical vein endothelial cells; Hydrogen peroxide; Oxidative stress; Peoniflorin; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ASCORBIC ACID; CASPASE 3; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PAEONIFLORIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL THERAPY; CELL VIABILITY; CHONDROPROTECTION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; NORMAL HUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; BENZOIC ACIDS; BRIDGED COMPOUNDS; CASPASE 3; CELL SURVIVAL; ENDOTHELIAL CELLS; GLUCOSIDES; HUMANS; HYDROGEN PEROXIDE; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; MITOGEN-ACTIVATED PROTEIN KINASE 3; OXIDATIVE STRESS; PAEONIA; PLANT EXTRACTS; PLANT ROOTS; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; UMBILICAL VEINS;

EID: 79960772762     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/y11-034     Document Type: Article

References (37)

1. Al Laham, F., Kälsch, AI., Heinrich, L., Birck, R., Kallenberg, C.G., Heeringa, P., and Yard, B. 2010. Inhibition of neutrophil-mediated roduction of reactive oxygen species (ROS) by endothelial cells is not impaired in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis patients. Clin. Exp. Immunol. 161(2): 268-275.
2. Babbar, N., and Casero, R.A., Jr. 2006. Tumor necrosis factor-a increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation- induced carcinogenesis. Cancer Res. 66(23): 11125-11130. doi:10.1158/0008-5472.CAN-06-3174.
3. Chambers, J.C., Haskard, D.O., and Kooner, J.S. 2001. Vascular endothelial function and oxidative stress mechanisms in patients with Behçet's syndrome. J. Am. Coll. Cardiol. 37(2): 517-520. doi:10.1016/S0735-1097(00)01137-2.
4. Chen, D.M., Xiao, L., Cai, X., Zeng, R., and Zhu, X.Z. 2006. Involvement of multitargets in paeoniflorin-induced preconditioning. J. Pharmacol. Exp. Ther. 319(1): 165-180. doi:10.1124/jpet. 106.104380.
5. Chen, T., Guo, Z.P., Jiao, X.Y., Jia, R.Z., Zhang, Y.H., Li, J.Y., et al. 2010. Peoniflorin suppresses tumor necrosis factor-a induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-kB and ERK pathway. Arch. Dermatol. Res. 303(5): 351-360 doi:10.1007/s00403-010-1116-6.
6. Chen, T., Guo, Z.P., Zhang, Y.H., Gao, Y., Liu, H.J., and Li, J.Y. 2011. Elevated serum heme oxygenase-1 and insulin-like growth factor-1 levels in patients with Henoch-Schonlein purpura. Rheumatol. Int. 31(3): 321-326. doi:10.1007/s00296-009-1254- 3.
7. Cini, M., Fariello, R.G., Bianchetti, A., and Moretti, A. 1994. Studies on lipid peroxidation in the rat brain. Neurochem. Res. 19(3): 283-288. doi:10.1007/BF00971576.
8. Corda, S., Laplace, C., Vicaut, E., and Duranteau, J. 2001. Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-a is mediated by ceramide. Am. J. Respir. Cell Mol. Biol. 24(6): 762-768.
9. Jaffe, E.A., Nachman, R.L., Becker, C.G., and Minick, C.R. 1973. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52(11): 2745-2756. doi:10.1172/JCI107470.
10. Janero, D.R. 1990. Malondialdehyde and thiobarbituric-acid reactivity as diagnostic indices of lipid peroxidation, and peroxidative tissue injury. Free Radic. Biol. Med. 9(6): 515-540. doi:10.1016/ 0891-5849(90)90131-2.
11. Jiang, W.L., Chen, X.G., Zhu, H.B., Gao, Y.B., Tian, J.W., and Fu, F. H. 2009. Paeoniflorin inhibits systemic inflammation and improves survival in experimental sepsis. Basic Clin. Pharmacol. Toxicol. 105(1): 64-71. doi:10.1111/j.1742-7843.2009.00415.x.
12. 2-mediated permeability: role of MAPK and occludin. Am. J. Physiol. Cell Physiol. 279(1): C21-C30.
13. Lee, Y.J., Kang, I.J., Bünger, R., and Kang, Y.H. 2004. Enhanced survival effect of pyruvate correlates MAPK and NF-kB activation in hydrogen peroxide-treated human endothelial cells. J. Appl. Physiol. 96(2): 793-801, discussion: 792. doi:10.1152/ japplphysiol.00797.2003.
14. Li, S.Y., Gomelsky, M., Duan, J., Zhang, Z., Gomelsky, L., Zhang, X., et al. 2004. Overexpression of aldehyde dehydrogenase-2 (ALDH2) transgene prevents acetaldehyde-induced cell injury in human umbilical vein endothelial cells: role of ERK and p38 mitogen-activated protein kinase. J. Biol. Chem. 279(12): 11244-11252. doi:10.1074/jbc.M308011200
15. Li, C.R., Zhou, Z., Zhu, D., Sun, Y.N., Dai, J.M., and Wang, S.Q. 2007. Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases. Int. J. Biochem. Cell Biol. 39(2): 426-438. doi:10.1016/j.biocel.2006.09.011.
16. Li, W.M., Liu, H.T., Li, X.Y., Wu, J.Y., Xu, G., Teng, Y.Z., et al. 2010. The effect of tetramethylpyrazine on hydrogen peroxideinduced oxidative damage in human umbilical vein endothelial cells. Basic Clin. Pharmacol. Toxicol. 106(1): 45-52.
17. Liu, C.L., Xie, L.X., Li, M., Durairajan, S.S., Goto, S., and Huang, J. D. 2007. Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling. PLoS ONE, 2(12): e1321. doi:10.1371/journal.pone.0001321.
18. Manning, R.D., Jr, Meng, S., and Tian, N. 2003. Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. Acta Physiol. Scand. 179(3): 243-250. doi:10.1046/j.0001-6772.2003. 01204.x.
19. Mao, Q.Q., Zhong, X.M., Feng, C.R., Pan, A.J., Li, Z.Y., and Huang, Z. 2010. Protective effects of paeoniflorin against glutamateinduced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism. Cell. Mol. Neurobiol. 30(7): 1059-1066. doi:10.1007/s10571-010-9537-5.
20. Mao, Q.Q., Xian, Y.F., Ip, S.P., Tsai, S.H., and Che, C.T. 2011. Protective effects of peony glycosides against corticosteroneinduced cell death in PC12 cells through antioxidant action. J. Ethnopharmacol. 133(3): 1121-1125. doi:10.1016/j.jep.2010.11. 043.
21. Michiels, C., Raes, M., Toussaint, O., and Remacle, J. 1994. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn- SOD for cell survival against oxidative stress. Free Radic. Biol. Med. 17(3): 235-248. doi:10.1016/0891-5849(94)90079-5.
22. Okutan, H., Ozcelik, N., Yilmaz, H.R., and Uz, E. 2005. Effects of caffeic acid phenethyl ester on lipid peroxidation and antioxidant enzymes in diabetic rat heart. Clin. Biochem. 38(2): 191-196. doi:10.1016/j.clinbiochem.2004.10.003.
23. Pawlak, K., Naumnik, B., Brzósko, S., Pawlak, D., and Myśliwiec, M. 2004. Oxidative stress - a link between endothelial injury, coagulation activation, and atherosclerosis in haemodialysis patients. Am. J. Nephrol. 24(1): 154-161. doi:10.1159/ 000076244.
24. Qian, Y.F., Wang, H., Yao, W.B., and Gao, X.D. 2008. Aqueous extract of the Chinese medicine, Danggui-Shaoyao-San, inhibits apoptosis in hydrogen peroxide-induced PC12 cells by preventing cytochrome c release and inactivating of caspase cascade. Cell Biol. Int. 32(2): 304-311.
25. 2-induced injury in primary human umbilical vein endothelial cells. J. Ethnopharmacol. 128(2): 438-445. doi:10.1016/j.jep.2010.01.031.
26. Su, J., Zhang, P., Zhang, J.J., Qi, X.M., Wu, Y.G., and Shen, J.J. 2010. Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats. Phytomedicine, 17(3-4): 254-260. doi:10.1016/j.phymed.2009.07.005.
27. Tam, L.S., Li, E.K., Leung, V.Y., Griffith, J.F., Benzie, I.F., Lim, P. L., et al. 2005. Effects of vitamins C and E on oxidative stress markers and endothelial function in patients with systemic lupus erythematosus: a double blind, placebo controlled pilot study. J. Rheumatol. 32(2): 275-282.
28. Wang, J., Shen, Y.H., Utama, B., Wang, J., LeMaire, S.A., Coselli, J. S., et al. 2006. HCMV infection attenuates hydrogen peroxide induced endothelial apoptosis - involvement of ERK pathway. EBS Lett. 580(11): 2779-2787. doi:10.1016/j.febslet.2006.04. 041
29. Wang, Q., Luo, W., Zhang, W., Dai, Z., Chen, Y., and Chen, J. 2007. Iron supplementation protects against lead-induced apoptosis through MAPK pathway in weanling rat cortex. Neurotoxicology, 28(4): 850-859. doi:10.1016/j.neuro.2007.04.004.
30. Wu, Y., Ren, K., Liang, C., Yuan, L., Qi, X., Dong, J., et al. 2009. Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes. J. Pharmacol. Sci. 109(1): 78-87. doi:10.1254/jphs.08112FP.
31. Xu, H., Gao, X., Song, J., Wang, F., Xu, Z., Lu, D., et al. 2010. Peoniflorin prevents the adhesion between inflammatory endothelial cells and leukocytes through inhibiting the activation of MAPKs and NF-kB. Drug Dev. Res. 71(5): 275-284. doi:10.1002/ ddr.20372.
32. Yang, Z., Mo, X., Gong, Q., Pan, Q., Yang, X., Cai, W., et al. 2008. Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose. Apoptosis, 13(11): 1331-1343. doi:10. 1007/s10495-008-0257-y.
33. Zhang, Q., Ye, D.Q., Chen, G.P., and Zheng, Y. 2010. Oxidative protein damage and antioxidant status in systemic lupus erythematosus. Clin. Exp. Dermatol. 35(3): 287-294. doi:10. 1111/j.1365-2230.2009.03437.x.
34. Zhong, S.Z., Ge, Q.H., Li, Q., Qu, R., and Ma, S.P. 2009. Peoniflorin ttentuates Ab((1-42))-mediated neurotoxicity by regulating alcium homeostasis and ameliorating oxidative stress in hippocampus f rats. J. Neurol. Sci. 280(1-2): 71-78. doi:10.1016/j.jns. 009.01.027.
35. Zhuang, S., Yan, Y., Daubert, R.A., Han, J., and Schnellmann, R.G. 2007. ERK promotes hydrogen peroxide-induced apoptosis hrough caspase-3 activation and inhibition of Akt in renal pithelial cells. Am. J. Physiol. Renal Physiol. 292(1): F440-F447. doi:10.1152/ajprenal.00170.2006.
36. Zmijewski, J.W., Moellering, D.R., Le Goffe, C., Landar, A., amachandran, A., and Darley-Usmar, V.M. 2005. Oxidized DL induces mitochondrially associated reactive oxygen/nitrogen pecies formation in endothelial cells. Am. J. Physiol. Heart Circ. hysiol. 289(2): H852-H861. doi:10.1152/ajpheart.00015.200
37. Zweier, J.L., and Talukder, M.A. 2006. The role of oxidants and free radicals in reperfusion injury. Cardiovasc. Res. 70(2): 181-190. doi:10.1016/j.cardiores.2006.02.025.