Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats

Phytomedicine

Volumn 17, Issue 3-4, 2010, Pages 254-260

  Su, Jing ^a   Zhang, Pei ^a   Zhang, Jing Jing ^a   Qi, Xiang Ming ^a   Wu, Yong Gui ^a   Shen, Ji Jia ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Mitogen activated protein kinase; NF B; Nitrotyrosine; Oxidative stress; Paeonia lactiflora; Total glucosides of paeony

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ALBUMIN; CATALASE; GLUTATHIONE PEROXIDASE; HERBACEOUS AGENT; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROTROPHIN 3; PAEONIA LACTIFLORA EXTRACT; SUPEROXIDE DISMUTASE; TOTAL GLUCOSIDES OF PAEONY; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG EFFECT; ENZYME ACTIVITY; GLOMERULUS; IN VIVO STUDY; INTERSTITIAL NEPHRITIS; KIDNEY FUNCTION; KIDNEY INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; THERAPY EFFECT; TREATMENT DURATION; URINARY EXCRETION; WESTERN BLOTTING;

ALBUMINURIA; ANIMALS; ANTIOXIDANTS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; GLUCOSIDES; KIDNEY; MALE; MALONDIALDEHYDE; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PAEONIA; PHYTOTHERAPY; RATS; RATS, WISTAR;

PAEONIA LACTIFLORA; PAEONIACEAE; RATTUS;

EID: 75249104928     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.07.005     Document Type: Article

References (24)

1. Anwar M.M., and Meki A.R. Oxidative stress in streptozotocin-induced diabetic rats: effects of garlic oil and melatonin. Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 135 (2003) 539-547
2. Bhatia S., Shukla R., Venkata Madhu S., Kaur Gambhir J., and Madhava Prabhu K. Antioxidant status, lipid peroxidation and nitric oxide end products in patients of type 2 diabetes mellitus with nephropathy. Clin. Biochem. 36 (2003) 557-562
3. Bursell S.E., Clermont A.C., Aiello L.P., and Aiello L.M. High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes. Diabetes Care 22 (1999) 1245-1251
4. Craven P.A., DeRubertis F.R., Kagan V.E., and Melhem M. Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes. J. Am. Soc. Nephrol. 8 (1997) 1405-1414
5. Derubertis F.R., Graven P.A., and Melhem M.F. Attenuation of renal injury in db/db mice overexpression superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction. Diabetes 50 (2004) 2114-2125
6. Guigliano D., Paolisso G., and Ceriello A. Oxidative stress and diabetic vascular complications. Diabetes 19 (1996) 257-267
7. Ha H., and Kim K.H. Role of oxidative stress in the development of diabetic nephropathy. Kidney Int. suppl. 51 (1995) 18-21
8. Ha H., and Lee H.B. Oxidative stress in diabetic nephropathy: basic and clinical information. Curr. Diabetes Rep. 1 (2001) 282-287
9. Liao H., Banbury L.K., and Leach D.N. Elucidation of danzhixiaoyao wan and its constituent herbs on antioxidant activity and inhibition of nitric oxide production. Evid. Based Complement. Alternat. Med. 4 (2007) 425-430
10. Lehmann R., and Schleicher E.D. Molecular mechanism of diabetic nephropathy. Clin. Chim. Acta 297 (2000) 135-144
11. Li C.R., Zhou Z., Zhu D., Sun Y.N., Dai J.M., and Wang S.Q. Protective effect of paeoniflorin on irradiation-induced cell damage involved in modulation of reactive oxygen species and the mitogen-activated protein kinases. Int. J. Biochem. Cell Biol. 39 (2007) 426-438
12. Liu B.F., Miyata S., Hirota Y., Higo S., Miyazaki H., Fukunaga M., Hamada Y., Ueyama S., and Muramoto O. Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney Int. 63 (2003) 947-957
13. Liu J., Jin D.Z., Xiao L., and Zhu X.Z. Paeoniflorin attenuates chroniccerebral hypoperfusion-induced learning dysfunction and brain damage in rats. Brain Res. 1089 (2006) 162-170
14. Nakagawa T., Goto H., Hikiami H., Yokozawa T., Shibahara N., and Shimada Y. Protective effects of keishbukuryogan on the kidney of spontaneously diabetic WBN/Kob rats. J. Ethnopharmacol. 110 (2007) 311-317
15. Okubo T., Nagai F., Seto T., Satoh K., Ushiyama K., and Kano I. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of moutan cortex and paeoniae radix. Biol. Pharm. Bull. 23 (2000) 199-203
16. Onozato M.L., Tojo A., Goto A., Fujita T., and Wilcox C.S. Oxidative stress and nitric oxide synthase in rat diabetic nephropathy:effect of ACEI and ARB. Kidney Int. 61 (2002) 186-194
17. Sun R., Yi Y.P., Zhang Z.P., Sun H., and Liu G.Q. Effects of paeoniflorin on pathological changes in global brain ischemia model rats. J. Chin. Med. 32 (2007) 2518-2522
18. Ulrich-Merzenich G., Zeitler H., Vetter H., and Kraft K. Synergy research: vitamins and secondary plant components in the maintenance of the redox-homeostasis and in cell signaling. Phytomedicine 16 (2009) 2-16
19. Wang B., Chen M.Z., and Xu S.Y. Regulatory mechanism of total glucosides of paeony on tumor necrosis factor production by peritoneal macrophages in rats. Chin. Pharmacol. Bull. 13 (1997) 255-257 (in Chinese)
20. Wang H., Wei W., Wang N.P., Wu C.Y., and Yan S.X. Effects of total glucosides of peony on immunological hepatic fibrosis in rats. World J. Gastroenterol. 11 (2005) 2124-2129
21. Welt K., Weiss J., Martin R., Hermsdorf T., Drews S., and Fitzl G. Ginkgo biloba extract protects rat kidney from diabetic and hypoxic damage. Phytomedicine 14 (2007) 196-203
22. Xu H.M., Wei W., and Jia X.Y. Effects and mechanisms of total glucosides of paeony on adjuvant arthritis in rats. J. Ethnopharmacol. 109 (2007) 442-448
23. Xu S.Y., Chen M.Z., and Wei W. Immunopharmacology and clinic. In: Zhou J.H., and Liu G.Z. (Eds). Progress in Pharmacology and Clinics of Chinese Materia Medical Research. 1st edition (1992), Science and Technology of China Press, Beijing 49-59 (in Chinese)
24. Zheng Y.Q., and Wei W. Total glucosides of paeony suppresses adjuvant arthritis in rats and intervenes cytokine-signaling between different types of synoviocyte. Immun. Int. 5 (2005) 1560-1573