Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Mukherjee, Malini ^a   Ge, Gouqing ^a   Zhang, Nenggang ^a   Huang, Eryong ^a   Nakamura, Lanelle V ^a   Minor, Marissa ^a   Fofanov, Viacheslav ^b   Rao, Pullivarthi H ^a   Herron, Alan ^a   Pati, Debananda ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Eureka Genomics Corp   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; SEPARASE; CELL CYCLE PROTEIN; PROTEINASE;

ANEUPLOIDY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B CELL LYMPHOMA; CARCINOGENESIS; CHROMOSOME SEGREGATION; DISEASE ACTIVITY; DNA DAMAGE; ENZYME INACTIVATION; ESPL1 GENE; FEMALE; GENE; GENETIC STABILITY; GERM LINE; HETEROZYGOSITY; LEUKEMIA; LIFESPAN; METAPHASE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; SPLEEN CELL; T CELL LYMPHOMA; ANIMAL; BONE MARROW; CELL PROLIFERATION; DISEASE COURSE; ENZYMOLOGY; GENETICS; HUMAN; LONGEVITY; METABOLISM; METASTASIS; PATHOLOGY; THYMOMA;

ANIMALIA; MUS; MUS MUSCULUS;

ANEUPLOIDY; ANIMALS; BONE MARROW; CELL CYCLE PROTEINS; CELL PROLIFERATION; DISEASE PROGRESSION; DNA DAMAGE; ENDOPEPTIDASES; FEMALE; HUMANS; LEUKEMIA; LONGEVITY; LYMPHOMA, B-CELL; LYMPHOMA, T-CELL; MICE; NEOPLASM METASTASIS; PHENOTYPE; THYMUS NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79960759629     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022167     Document Type: Article

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