Inhibitory phosphorylation of separase is essential for genome stability and viability of murine embryonic germ cells

PLoS Biology

Volumn 6, Issue 1, 2008, Pages 0052-0062

  Huang, Xingxu ^a   Andreu Vieyra, Claudia V ^a   York, J Philippe ^a   Hatcher, Rashieda ^a   Lu, Tao ^b   Matzuk, Martin M ^a   Zhang, Pumin ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; COHESIN; CYSTEINE PROTEINASE; SECURIN; SEPARASE; SERINE; CELL CYCLE PROTEIN; PROTEINASE;

AMINO ACID SUBSTITUTION; ANAPHASE; ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CHROMOSOME SEGREGATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENOMIC INSTABILITY; GERM CELL; MITOSIS INHIBITION; MOUSE; MOUSE STRAIN; MUTATION; NONHUMAN; PRIMORDIUM; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SISTER CHROMATID; ANIMAL; ANIMAL EMBRYO; CELL SURVIVAL; CHROMATID; CYTOLOGY; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; METABOLISM; MITOSIS; PHOSPHORYLATION; POINT MUTATION;

MURINAE; MUS;

ANIMALS; CELL CYCLE PROTEINS; CELL SURVIVAL; CHROMATIDS; EMBRYO, MAMMALIAN; ENDOPEPTIDASES; GENOMIC INSTABILITY; GERM CELLS; MICE; MITOSIS; PHOSPHORYLATION; POINT MUTATION; SEPARASE;

EID: 38949146407     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0060015     Document Type: Article

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