C17 prevents inflammatory arthritis and associated joint destruction in mice

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Chao, Connie ^a   Joyce Shaikh, Barbara ^a   Grein, Jeff ^a   Moshrefi, Mehrdad ^a   Raoufi, Fahimeh ^a   Laface, Drake M ^a   McClanahan, Terril K ^a   Bourne, Patricia A ^a   Pierce, Robert H ^a   Gorman, Daniel M ^a   Pflanz, Stefan ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C17; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; C17 PROTEIN, HUMAN; PLASMA PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; CARTILAGE CELL; CONTROLLED STUDY; DRUG EFFECT; EDEMA; EMBRYO; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYDRODYNAMICS BASED TRANSFECTION; IMMUNOREGULATION; IN VIVO STUDY; JOINT DEGENERATION; MALE; MOUSE; NONHUMAN; PROTECTION; PROTEIN EXPRESSION; AMINO ACID SEQUENCE; ANIMAL; BLOOD; BONE DISEASE; CARTILAGE; CELL STRAIN HEK293; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; IMMUNOLOGY; INFLAMMATION; JOINT; METABOLISM; MOLECULAR GENETICS; PATHOLOGY;

MUS;

AMINO ACID SEQUENCE; ANIMALS; ARTHRITIS; BIOLOGICAL MARKERS; BLOOD PROTEINS; BONE DISEASES; CARTILAGE; CHONDROCYTES; CYTOKINES; GENE EXPRESSION REGULATION; HEK293 CELLS; HOMEOSTASIS; HUMANS; INFLAMMATION; JOINTS; MALE; MICE; MOLECULAR SEQUENCE DATA; RANK LIGAND;

EID: 79960716703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022256     Document Type: Article

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