Inositol hexakisphosphate kinases induce cell death in Huntington disease

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26680-26686

  Nagata, Eiichiro ^a   Saiardi, Adolfo ^b   Tsukamoto, Hideo ^a   Okada, Yoshinori ^a   Itoh, Yoshiko ^a   Satoh, Tadayuki ^a   Itoh, Johbu ^a   Margolis, Russell L ^c   Takizawa, Shunya ^a   Sawa, Akira ^c   Takagi, Shigeharu ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT PHOSPHORYLATION; APOPTOTIC CELL DEATH; AUTOPHAGOSOMES; DIPHOSPHOINOSITOL PENTAKISPHOSPHATE; DOWN-REGULATION; HUNTINGTON DISEASE; IN-CONTROL; INOSITOL HEXAKISPHOSPHATE; INOSITOL PYROPHOSPHATE; MAMMALIAN CELLS; OVER-EXPRESSION;

ALCOHOLS; CELL DEATH; DISEASE CONTROL; ENZYMES; MAMMALS; PHOSPHORYLATION;

SUGARS;

INOSITOL HEXAKISPHOSPHATE KINASE 2; PHOSPHOTRANSFERASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL NUCLEUS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; LYMPHOBLAST; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL NUCLEUS; CYTOPLASM; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; HUNTINGTON DISEASE; LYMPHOCYTES; PHOSPHORYLATION; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PHYTIC ACID; PROTO-ONCOGENE PROTEINS C-AKT;

MAMMALIA;

EID: 79960692647     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.220749     Document Type: Article

References (33)

1. Mikoshiba, K., Furuichi, T., and Miyawaki, A. (1994) Semin. Cell Biol. 5, 273-281
2. Mikoshiba, K. (2007) J. Neurochem. 102, 1426-1446
3. Losito, O., Szijgyarto, Z., Resnick, A. C., and Saiardi, A. (2009) PLoS ONE 4, e5580
4. Bennett, M., Onnebo, S. M., Azevedo, C., and Saiardi, A. (2006) Cell. Mol. Life Sci. 63, 552-564
5. Nagata, E., Luo, H. R., Saiardi, A., Bae, B. I., Suzuki, N., and Snyder, S. H. (2005) J. Biol. Chem. 280, 1634-1640
6. Glennon, M. C., and Shears, S. B. (1993) Biochem. J. 293, 583-590
7. Saiardi, A., Sciambi, C., McCaffery, J. M., Wendland, B., and Snyder, S. H. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 14206-14211
8. Saiardi, A., Resnick, A. C., Snowman, A. M., Wendland, B., and Snyder, S. H. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 1911-1914
9. Rhodes, D., Fairall, L., Simonsson, T., Court, R., and Chapman, L. (2002) EMBO Rep. 3, 1139-1145
10. Bhandari, R., Juluri, K. R., Resnick, A. C., and Snyder, S. H. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 2349-2353
11. Illies, C., Gromada, J., Fiume, R., Leibiger, B., Yu, J., Juhl, K., Yang, S. N., Barma, D. K., Falck, J. R., Saiardi, A., Barker, C. J., and Berggren, P. O. (2007) Science 318, 1299-1302
12. Morrison, B. H., Bauer, J. A., Hu, J., Grane, R. W., Ozdemir, A. M., Chawla- Sarkar, M., Gong, B., Almasan, A., Kalvakolanu, D. V., and Lindner, D. J. (2002) Oncogene 21, 1882-1889
13. Voglmaier, S. M., Bembenek, M. E., Kaplin, A. I., Dormán, G., Olszewski, J. D., Prestwich, G. D., and Snyder, S. H. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 4305-4310
14. Nagata, E., Saiardi, A., Tsukamoto, H., Satoh, T., Itoh, Y., Itoh, J., Shibata, M., Takizawa, S., and Takagi, S. (2010) Int. J. Biochem. Cell Biol. 42, 2065-2071
15. Sawa, A., Wiegand, G. W., Cooper, J., Margolis, R. L., Sharp, A. H., Lawler, J. F., Jr., Greenamyre, J. T., Snyder, S. H., and Ross, C. A. (1999) Nat. Med. 5, 1194-1198
16. Penno, M. B., Pedrotti-Krueger, M., and Ray, T. (1993) J. Tissue Cult. Methods 15, 43-48
17. Itoh, Y., Tanaka, S., Takekoshi, S., Itoh, J., and Osamura, R. Y. (1996) Pathol. Int. 46, 726-737
18. Azevedo, C., and Saiardi, A. (2006) Nat. Protoc. 1, 2416-2422
19. Saiardi, A., Nagata, E., Luo, H. R., Snowman, A. M., and Snyder, S. H. (2001) J. Biol. Chem. 276, 39179-39185
20. Sarkar, S., and Rubinsztein, D. C. (2008) FEBS J. 275, 4263-4270
21. Heng, M. Y., Duong, D. K., Albin, R. L., Tallaksen-Greene, S. J., Hunter, J. M., Lesort, M. J., Osmand, A., Paulson, H. L., and Detloff, P. J. (2010) Hum. Mol. Genet. 19, 3702-3720
22. Nagata, E., Sawa, A., Ross, C. A., and Snyder, S. H. (2004) Neuroreport 15, 1325-1328
23. Grewal, S. S. (2009) Int. J. Biochem. Cell Biol. 41, 1006-1010
24. Schmelzle, T., and Hall, M. N. (2000) Cell 103, 253-262
25. Humbert, S., Bryson, E. A., Cordelières, F. P., Connors, N. C., Datta, S. R., Finkbeiner, S., Greenberg, M. E., and Saudou, F. (2002) Dev. Cell 2, 831-837
26. Colin, E., Régulier, E., Perrin, V., Dürr, A., Brice, A., Aebischer, P., Déglon, N., Humbert, S., and Saudou, F. (2005) Eur. J. Neurosci. 21, 1478-1488
27. Luo, H. R., Huang, Y. E., Chen, J. C., Saiardi, A., Iijima, M., Ye, K., Huang, Y., Nagata, E., Devreotes, P., and Snyder, S. H. (2003) Cell 114, 559-572
28. Chakraborty, A., Koldobskiy, M. A., Bello, N. T., Maxwell, M., Potter, J. J., Juluri, K. R., Maag, D., Kim, S., Huang, A. S., Dailey, M. J., Saleh, M., Snowman, A. M., Moran, T. H., Mezey, E., and Snyder, S. H. (2010) Cell 143, 897-910
29. Ma, T., Hoeffer, C. A., Capetillo-Zarate, E., Yu, F., Wong, H., Lin, M. T., Tampellini, D., Klann, E., Blitzer, R. D., and Gouras, G. K. (2010) PLoS ONE 5, e12845
30. Caccamo, A., Majumder, S., Richardson, A., Strong, R., and Oddo, S. (2010) J. Biol. Chem. 285, 13107-13120
31. Spilman, P., Podlutskaya, N., Hart, M. J., Debnath, J., Gorostiza, O., Bredesen, D., Richardson, A., Strong, R., and Galvan, V. (2010) PLoS ONE 5, e9979
32. Kroemer, G., and Levine, B. (2008) Nat. Rev. Mol. Cell Biol. 9, 1004-1010
33. Martinez-Vicente, M., Talloczy, Z., Wong, E., Tang, G., Koga, H., Kaushik, S., de Vries, R., Arias, E., Harris, S., Sulzer, D., and Cuervo, A. M. (2010) Nat. Neurosci. 13, 567-576