Structural analysis of papain-like NlpC/p60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Xu, Qingping ^a,b   Rawlings, Neil D ^c   Chiu, Hsiu Ju ^a,b   Jaroszewski, Lukasz ^a,d,e   Klock, Heath E ^a,f   Knuth, Mark W ^a,f   Miller, Mitchell D ^a,b   Elsliger, Marc Andre ^a,g   Deacon, Ashley M ^a,b   Godzik, Adam ^a,d,e   Lesley, Scott A ^a,f,g   Wilson, Ian A ^a,g  

^a Joint Center for Structural Genomics   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BURNHAM INSTITUTE   (United States)

^f GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^g SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; FATTY ACID; LYSINE; PAPAIN; PROTEIN P60; TYROSINE; BACTERIAL PROTEIN; LIGAND; LIPOPROTEIN; NLPD PROTEIN, BACTERIA; P60 PROTEIN, BACTERIA;

AMINO ACID SEQUENCE; ARTICLE; BACILLUS CEREUS; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME LOCALIZATION; HYDROPHOBICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; STRUCTURAL HOMOLOGY; STRUCTURE ANALYSIS; BIOCATALYSIS; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HUMAN; LIPID METABOLISM; METABOLISM; MOLECULAR GENETICS;

BACILLUS CEREUS; EUKARYOTA;

AMINO ACID SEQUENCE; BACILLUS CEREUS; BACTERIAL PROTEINS; BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; FATTY ACIDS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; LIPID METABOLISM; LIPOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PAPAIN;

EID: 79960670480     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022013     Document Type: Article

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