A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture

Virology

Volumn 374, Issue 2, 2008, Pages 506-514

  Senkevich, Tatiana G ^a   Wyatt, Linda S ^a   Weisberg, Andrea S ^a   Koonin, Eugene V ^b   Moss, Bernard ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Cysteine histidine dyad; Papain fold; Vaccinia virus G6R gene; Virus pathogenesis

Indexed keywords

CYSTEINE; PAPAIN; PROTEIN G6; PROTEIN P60; VIRUS PROTEIN;

ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE SEQUENCE; GENETIC CONSERVATION; NONHUMAN; NULL ALLELE; POXVIRUS INFECTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR GENE; VACCINIA VIRUS; VIRUS CELL INTERACTION; VIRUS ENVELOPE; VIRUS GENE; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHICK EMBRYO; CONSERVED SEQUENCE; CYSTEINE; FIBROBLASTS; HISTIDINE; HUMANS; KERATINOCYTES; MOLECULAR SEQUENCE DATA; PAPAIN; PEPTIDE HYDROLASES; PROTEIN FOLDING; VACCINIA VIRUS; VIRAL PROTEINS; VIRION; VIRULENCE; VIRUS REPLICATION;

HEXAPODA; MUS; POXVIRIDAE; VACCINIA VIRUS; VERTEBRATA;

EID: 42649122968     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.01.009     Document Type: Article

References (22)

1. Aldaz-Carroll L., Whitbeck J.C., Ponce de Leon M., Lou H., Pannell L.K., Lebowitz J., Fogg C., White C., Moss B., Cohen G.H., and Eisenberg R.J. Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene. Virology 341 (2005) 59-71
2. Anantharaman V., and Aravind L. Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol. 4 (2003) R11
3. Carroll M., and Moss B. Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line. Virology 238 (1997) 198-211
4. Chakrabarti S., Sisler J.R., and Moss B. Compact, synthetic, vaccinia virus early/late promoter for protein expression. BioTechniques 21 (1997) 1904-1907
5. Da Fonseca F., and Moss B. Poxvirus DNA topoisomerase knockout mutant exhibits decreased infectivity associated with reduced early transcription. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 11291-11296
6. Earl P.L., Moss B., Wyatt L.S., and Carroll M.W. Generation of recombinant vaccinia viruses. In: Ausubel F.M., Brent R., Kingston R.E., Moore D.D., Seidman J.G., Smith J.A., and Struhl K. (Eds). Current Protocols in Molecular Biology vol. 2 (1998), Greene Publishing Associates & Wiley Interscience, New York 16.17.1-16.17.19
7. Garcia A.D., Aravind L., Koonin E.V., and Moss B. Bacterial-type DNA Holliday junction resolvases in eukaryotic viruses. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 8926-8931
8. Goebel, S.J., Johnson, G.P., Perkus, M.E., Davis, S.W., Winslow, J.P., Paoletti, E., 1990. The complete DNA sequence of vaccinia virus. Virology 179, 247-266; 517-563.
9. Iyer L.A., Balaji S., Koonin E.V., and Aravind L. Evolutionary genomics of nucleo-cytoplasmic large DNA viruses. Virus Res. 117 (2006) 156-184
10. Kattenhorn L.M., Korbel G.A., Kessler B.M., Spooner E., and Ploegh H.L. A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae. Mol. Cell 19 (2005) 547-557
11. Law M., Putz M.M., and Smith G.L. An investigation of the therapeutic value of vaccinia-immune IgG in a mouse pneumonia model. J. Gen. Virol. 86 (2005) 991-1000
12. Mondal M.S., Ruiz A., Bok D., and Rando R.R. Lecithin retinol acyltransferase contains cysteine residues essential for catalysis. Biochemistry 39 (2000) 5215-5220
13. Moss B. Poxviridae: the viruses and their replication. In: Knipe D.M. (Ed). Fields Virology vol. 2 (2007), Lippincott Williams & Wilkins, Philadelphia 2905-2946 2 vols
14. Parrish S., and Moss B. Characterization of a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression. J. Virol. 80 (2006) 553-561
15. Roizman B., Knipe D.M., and Whitley R.J. Herpes simplex viruses. In: Knipe D.M., and Howley P.M. (Eds). Fields Virology vol. 2 (2007), Lippincott Williams & Wilkins, Philadelphia 2501-2601
16. Schlieker C., Korbel G.A., Kattenhorn L.M., and Ploegh H.L. A deubiquitinating activity is conserved in the large tegument protein of the Herpesviridae. J. Virol. 79 (2005) 15582-15585
17. Senkevich T.G., Weisberg A., and Moss B. Vaccinia virus E10R protein is associated with the membranes of intracellular mature virions and has a role in morphogenesis. Virology 278 (2000) 244-252
18. Szajner P., Jaffe H., Weisberg A.S., and Moss B. Vaccinia virus G7L protein interacts with the A30L protein and is required for association of viral membranes with dense viroplasm to form immature virions. J. Virol. 77 (2003) 3418-3429
19. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25 (1997) 4876-4882
20. Upton C., Slack S., Hunter A.L., Ehlers A., and Roper R.L. Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome. J. Virol. 77 (2003) 7590-7600
21. Williamson J.D., Reith R.W., Jeffrey L.J., Arrand J.R., and Mackett M. Biological characterization of recombinant vaccinia viruses in mice infected by the respiratory route. J. Gen. Virol. 71 (1990) 2761-2767
22. Zhang Y., and Moss B. Inducer-dependent conditional-lethal mutant animal viruses. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 1511-1515