Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase

EMBO Journal

Volumn 25, Issue 24, 2006, Pages 5970-5982

  Pai, Chien Hua ^a,b   Chiang, Bing Yu ^a,c   Ko, Tzu Ping ^a   Chou, Chia Cheng ^d   Chong, Cheong Meng ^a   Yen, Fang Jiun ^a   Chen, Shoujun ^e   Coward, James K ^c   Wang, Andrew H J ^a,c,d   Lin, Chun Hung ^a,c,d  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d GENOMICS RESEARCH CENTER   (Taiwan)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Binding site; Glutathionylspermidine; Mechanism; Structure; Trypanothione

Indexed keywords

GLUTATHIONE SYNTHASE; SPERMIDINE SYNTHASE; TRYPANOTHIONE;

ARTICLE; BACTERIAL TRANSLOCATION; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DETERMINATION; DRUG STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; AMIDE SYNTHASES; AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ELECTROSTATICS; ENZYME INHIBITORS; ESCHERICHIA COLI; GLUTATHIONE; HUMANS; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; PHOSPHATES; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; SPERMIDINE; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; PROTOZOA;

EID: 33845691877     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601440     Document Type: Article

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