Association of VSNL1 with schizophrenia, frontal cortical function, and biological significance for its gene product as a modulator of cAMP levels and neuronal morphology

Translational Psychiatry

Volumn 1, Issue , 2011, Pages

  Braunewell, K H ^a,b   Dwary, A D ^a   Richter, F ^b   Trappe, K ^b   Zhao, C ^b   Giegling, I ^c   Schonrath K ^b   Rujescu, D ^c  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Cyclic AMP; Dendritic growth; Differentiation; Dopaminergic; Hippocampal

Indexed keywords

CYCLIC AMP; NEUROCALCIN; VSNL1 PROTEIN, HUMAN; VSNL1 PROTEIN, RAT;

ADULT; ANIMAL; ARTICLE; BIOSYNTHESIS; DENDRITE; FEMALE; FRONTAL LOBE; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; HUMAN; MALE; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; WISTAR RAT;

ADULT; ANIMALS; CYCLIC AMP; DENDRITES; FEMALE; FRONTAL LOBE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HIPPOCAMPUS; HUMANS; MALE; NEUROCALCIN; NEURONS; POLYMORPHISM, SINGLE NUCLEOTIDE; RATS; RATS, WISTAR; SCHIZOPHRENIA;

EID: 79960631803     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2011.20     Document Type: Article

References (57)

1. Egan MF, Weinberger DR. Neurobiology of schizophrenia. Curr Opin Neurobiol 1997; 7: 701-707. (Pubitemid 27500832)
2. Lewis DA, Levitt P. Schizophrenia as a disorder of neurodevelopment. Annu RevNeurosci 2002; 25: 409-432. (Pubitemid 34748023)
3. Saha S, Chant D, Welham J, McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Med 2005; 2: e141.
4. Bellon A. New genes associated with schizophrenia in neurite formation: a review of cell culture experiments. Mol Psychiatry 2007; 12: 620-629. (Pubitemid 46998253)
5. Arnold SE, Lee VM-Y, Gur RE, Trojanowski JQ. Abnormal expression of two microtubule- associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia. Proc Natl Acad Sci USA 1991; 88:10850-10854. (Pubitemid 21915936)
6. Jones LB, Johnson N, Byne W. Alterations in MAP2 immunocytochemistry in area 9 and 32 of schizophrenic prefrontal cortex. Psychiatry Res 2002; 114:137-148. (Pubitemid 34756636)
7. Villegas R, Villegas GM, Longart M, Hernandez M, Maqueira B, Buonanno A et al. Neuregulin found in cultured-sciatic nerve conditioned medium causes neuronal differentiation of PC12 cells. Brain Res 2000; 852: 305-318. (Pubitemid 30035167)
8. Selemon LD, Goldman-Rakic PS. The reduced neurophil hypothesis: a circuit based model of schizophrenia. Biol Psychiatry 1999; 45:17-25. (Pubitemid 29049200)
9. Angelucci F, Brené S, Mathé AA. BDNF in schizophrenia, depression and corresponding animal models. Mol Psychiatry 2005; 10: 345-352.
10. Venkatasubramanian G, Chittiprol S, Neelakantachar N, Naveen MN, Thirthall J, Gangadhar BN et al. Insulin and insulin-like growth factor-1 abnormalities in antipsychotic- naive schizophrenia. Am J Psychiatry 2007; 164:1557-1560. (Pubitemid 350069735)
11. Laurino L, Wang XX, de la Houssaye BA, Sosa L, Dupraz S, Caceres A et al. PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. J Cell Sci 2005; 118: 3653-3663. (Pubitemid 41309412)
12. Jiang H, Guo W, Liang X, Rao Y. Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3b and its upstream regulators. Cell 2005; 120:123-135. (Pubitemid 40094608)
13. Miyoshi K, Honda A, Baba K, Taniguchi M, Oono K, Fujita T et al. Disrupted-In- Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol Psychiatry 2003; 8: 685-694 . (Pubitemid 36976300)
14. Millar JK, Pickard BS, Mackie S, James R, Christie S, Buchanan SR et al. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 2005; 310:1187-1191. (Pubitemid 41681745)
15. Cai D, Qiu J, Cao Z, McAtee M, Bregman BS, Filbin MT. Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. J Neurosci 2001; 21: 4731-4739. (Pubitemid 32565631)
16. Braunewell KH, Gundelfinger ED. Intracellular neuronal calcium sensor proteins, a family of EF-hand calcium binding proteins in search of a function. Cell Tissue Res 1999; 295:1-12. (Pubitemid 29011934)
17. Burgoyne RD. Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling. Nat Rev Neurosci 2007; 3:182-193. (Pubitemid 46294665)
18. Braunewell K-H. The dark side of Ca2+ signaling by neuronal Ca2+- sensor proteins: from Alzheimer's disease to cancer. Trends Pharmacol Sci 2005; 26: 345-351. (Pubitemid 40848495)
19. Hong KS, Won HH, Cho EY, Jeun HO, Cho SS, Lee YS et al. Genome-widely significant evidence of linkage of schizophrenia to chromosomes 2p24.3 and 6q27 in an SNP- Based analysis of Korean families. Am J Med Genet B Neuropsychiatr Genet 2009; 150B: 647-652.
20. Kim S, Webster MJ. Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders. Mol Psychiatry 2011; 16: 452-461.
21. Bernstein HG, Braunewell KH, Spilker C, Danos P, Baumann B, Diekmann S et al. Hippocampal expression of the calcium sensor protein VILIP-1 in schizophrenia. Neuroreport 2002; 23: 393-396. (Pubitemid 34293176)
22. Bernstein HG, Becker A, Keilhoff G, Gorcyca WA, Braunewell KH, Grecksch G. Ketamine induced changes of the expression of neuronal calcium sensor proteins VILIP-1, -3 and hippocalcin in a partial schizophrenia model in rats. Neurosci Lett 2003; 339: 95-98. (Pubitemid 36254785)
23. Gierke P, Zhao C, Bernstein HG, Noack C, Anand R, Heinemann U et al. Implication of neuronal Ca2+-sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia. Neurobiol Dis 2008; 32: 162-175.
24. Miklos GL, Maleszka R. Microarray reality checks in the context of a complex disease. Nat Biotechnol 2004; 22: 615-621. (Pubitemid 38585915)
25. Vercauteren FGG, Flores G, Ma W, Chabot J-G, Geenen L, Clerens S et al. An organelle proteomic method to study neurotransmission-related proteins, applied to a neurodevelopmental model of schizophrenia. Proteomics 2007; 7: 3569-3579. (Pubitemid 47597678)
26. Beveridge NJ, Tooney PA, Carroll AP, Gardiner E, Bowden N, Scott RJ et al. Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet 2008; 17: 1156-1168. (Pubitemid 351494187)
27. Altar CA, Hunt RA, Jurata LW, Webster MJ, Derby E, Gallagher P et al. Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cells. Biol Psychiatry 2008; 64:1077-1087.
28. Lenz SE, Henschel Y, Zopf D, Voss B, Gundelfinger ED. VILIP, a cognate protein of the retinal calcium binding proteins visinin and recoverin, is expressed in the developing chicken brain. Brain Res Mol Brain Res 1992; 151:133-140.
29. Braunewell KH, Gundelfinger ED. Low level expression of calcium-sensor protein VILIP induces cAMP-dependent differentiation in rat C6 glioma cells. Neurosci Lett 1997; 234: 139-142. (Pubitemid 27452112)
30. Braunewell KH, Spilker C, Behnisch T, Gundelfinger ED. The neuronal calcium-sensor protein VILIP modulates cAMP accumulation in stably transfected C6 glioma cells: aminoterminal myristoylation determines functional activity. J Neurochem 1997; 68: 2129-2139. (Pubitemid 27176151)
31. Dai FF, Zhang Y, Kang Y, Wang Q, Gaisano HY, Braunewell KH et al. The neuronal Ca2+ sensor protein visinin-like protein-1 is expressed in pancreatic islets and regulates insulin secretion. J Biol Chem 2006; 281: 21942-22153.
32. Mahloogi H, Gonzailez-Guerrico AM, Lopez De Cicco R, Bassi DE, Goodrow T et al. Overexpression of the calcium sensor visinin-like protein-1 leads to a cAMP-mediated decrease of in vivo and in vitro growth and invasiveness of squamous cell carcinoma cells. Cancer Res 2003; 63: 4997-5004. (Pubitemid 37022637)
33. Baptiste DC, Fehlings MG. Pharmacological approaches to repair the injured spinal cord. J Neurotrauma 2006; 23: 318-334. (Pubitemid 43726313)
34. Shad MU, Tamminga CA, Cullum M, Haas GL, Keshavan MS. Insight and frontal cortical function in schizophrenia: a review. Schizophr Res 2006; 86: 54-70. (Pubitemid 44234058)
35. Spilker C, Dresbach T, Braunewell KH. Reversible translocation and activity-dependent localization of the calcium-myristoyl switch protein VILIP-1 to different membrane compartments in living hippocampal neurons. J Neurosci 2002; 22: 7331-7339. (Pubitemid 35386332)
36. First MB, Spitzer RL, Gibbon M, Williams BW, Benjamin L. Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II). Biometrics Research Department, New York State Psychiatric Institute: New York, USA, 1990.
37. First MB, Spitzer RL, Gibbon M, Williams JB. Structured Clinical Interview for DSM-IV Axis I Disorders - Patient Edition (SCID - IIP, Version 2.0). Biometrics Research Department, New York State Psychiatric Institute: New York, USA, 1995.
38. Van den Oord EJ, Rujescu D, Robles JR, Giegling I, Birrell C, BukszárJ et al. Factor structure and external validity of the PANSS revisited. Schizophr Res 2006; 82: 213-223. (Pubitemid 43290685)
39. Rice JP, Reich T, Bucholz K, Neuman RJ, Fishman R, Rochberg N. Comparison of direct interview and family history diagnoses of alcohol dependence. Alcohol Clin Exp Res 1995; 19: 1018-1023.
40. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State (a practical method for grading the state of patients for the clinician). J Psychiatr Res 1975; 12:189-198.
41. Heaton RK. Wisconsin Card Sorting Test: Computer Version 4 - Research edition. Psychological Assessment Resources: Florida, USA, 2003.
42. Stefansson S, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D et al. Common variants conferring risk of schizophrenia. Nature 2009; 460: 744-747.
43. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D et al. PLINK: a toolset for whole-genome association and population-based linkage analysis. Am J Hum Genet 2007; 81: 559-575. (Pubitemid 47330214)
44. Sholl DA. Dendritic organization in the neurons of the visual and motor cortices of the cat. J Anat 1953; 87: 387-406.
45. Prentice KJ, Gold JM, Buchanan RW. The Wisconsin Card Sorting impairment in schizophrenia is evident in the first four trials. Schizophr Res 2008; 106: 81-87.
46. Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM et al. Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Arch Gen Psychiatry 2010; 67: 692-700.
47. Lee JM, Blennow K, Andreasen N, Laterza O, Modur V, Olander J et al. The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients. Clin Chem 2008; 54:1617-1623.
48. Gómez Ravetti M, Rosso OA, Berretta R, Moscato P. Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One 2010; 15: e10153.
49. Hannila SS, Filbin MT. The role of cyclic AMP signaling in promoting axonal regeneration after spinal cord injury. Exp Neurol 2008; 209: 321-332. (Pubitemid 351174133)
50. Mingorance-Le Meur A, O'Connor TP. Neurite consolidation is an active process requiring constant repression of protrusive activity. EMBO J 2009; 28: 248-260.
51. Li H, Chen G, Zhou B, Duan S. Actin filament assembly by myristoylated alanine-rich C kinase substrate-phosphatidylinositol-4,5-diphosphate signaling is critical for dendrite branching. Mol Biol Cell 2008; 19: 4804-4813.
52. Nguyen L, He Q, Meiri KF. Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution. Mol Cell Neurosci 2009; 41: 62-73.
53. Jan YN, Jan LY. Branching out: mechanisms of dendritic arborization. Nat Rev Neurosci 2010; 11:316-328.
54. Dailey ME, Smith SJ. The dynamics of dendritic structure in developing hippocampal slices. J Neurosci 1996; 16: 2983-2994. (Pubitemid 26121841)
55. Yuste R, Bonhoeffer T. Genesis of dendritic spines: insights from ultrastructural and imaging studies. Nat Rev Neurosci 2004; 5: 24-34. (Pubitemid 38076181)
56. Ehlers MD. Dendrite development: a surprising origin. J Cell Biol 2005; 170: 517-519. (Pubitemid 41186926)
57. Karlsgodt KH, Sun D, Jimenez AM, Lutkenhoff ES, Willhite R, van Erp TG et al. Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia. Dev Psychopathol 2008; 20:1297-1327.