Regulation of GAP-43 at serine 41 acts as a switch to modulate both intrinsic and extrinsic behaviors of growing neurons, via altered membrane distribution

Molecular and Cellular Neuroscience

Volumn 41, Issue 1, 2009, Pages 62-73

  Nguyen, Lilly ^a   He, Qin ^b   Meiri, Karina F ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

cDNA; Cell cell adhesion; Filopodia formation; GAP 43; Neurotubulin; Nuerite outgrowth; PI3 kinase; PKC; SY5Y neuroblastoma; Transfection

Indexed keywords

ALANINE; ASPARTIC ACID; COMPLEMENTARY DNA; F ACTIN; NERVE CELL ADHESION MOLECULE; NEUROMODULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RETINOIC ACID; SERINE; TUBULIN;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; FILOPODIUM; GENE OVEREXPRESSION; GROWTH CONE; GROWTH INHIBITION; GROWTH REGULATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MONOLAYER CULTURE; NERVE CELL MEMBRANE; NERVE FIBER GROWTH; NEURITE; NEUROBLASTOMA CELL; NEUROPROTECTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; CAVEOLINS; CELL ADHESION; CELL LINE, TUMOR; CELL MEMBRANE; CHOLESTEROL; DETERGENTS; GAP-43 PROTEIN; HUMANS; MEMBRANE MICRODOMAINS; NEURAL CELL ADHESION MOLECULES; NEURONS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PSEUDOPODIA; RATS; SERINE; SIGNAL TRANSDUCTION; TRETINOIN;

EID: 64849097192     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.01.011     Document Type: Article

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