Implication of neuronal Ca2+-sensor protein VILIP-1 in the glutamate hypothesis of schizophrenia

Neurobiology of Disease

Volumn 32, Issue 1, 2008, Pages 162-175

  Gierke, Paul ^a   Zhao, CongJian ^a   Bernstein, Hans Gert ^b   Noack, Cornelia ^a   Anand, Rene ^c   Heinemann, Uwe ^a   Braunewell, Karl Heinz ^a,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Ca2+ binding protein; Disinhibitory interneurons; Hippocampal neurons; Metabotropic glutamate receptors; Nicotinic acetylcholine receptor, NMDA hypofunction; Schizophrenia

Indexed keywords

ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR; CALRETININ; CHOLINERGIC RECEPTOR; DIZOCILPINE; GLUTAMIC ACID; KETAMINE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG; VISININ; VISININ LIKE PROTEIN 1; CALCIUM; INTRACELLULAR CALCIUM SENSING PROTEIN; METABOTROPIC GLUTAMATE RECEPTOR TYPE 1; NEUROCALCIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; VSNL1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CELL CULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IN VITRO STUDY; INTERNEURON; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; SCHIZOPHRENIA; SYNAPTIC TRANSMISSION; ANIMAL; COMPARATIVE STUDY; DENTATE GYRUS; FEMALE; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CALCIUM; CELLS, CULTURED; DENTATE GYRUS; FEMALE; GLUTAMIC ACID; HIPPOCAMPUS; HUMANS; INTERNEURONS; INTRACELLULAR CALCIUM-SENSING PROTEINS; KETAMINE; MALE; NEUROCALCIN; NEURONS; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, NICOTINIC; SCHIZOPHRENIA;

EID: 51549097114     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.07.008     Document Type: Article

References (59)

1. Alkondon M., and Albuquerque E.X. Nicotinic acetylcholine receptor alpha7 and alpha4beta2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus. J. Neurophysiol. 86 (2001) 3043-3055
2. Alkondon M., and Albuquerque E.X. A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons. J. Neurophysiol. 87 (2002) 1651-1654
3. Beasley C.L., and Reynolds G.P. Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics. Schizophr. Res. 24 (1997) 349-355
4. Benes F.M. Evidence for altered trisynaptic circuitry in schizophrenic hippocampus. Biol. Psychiatry. 46 (1999) 589-599
5. Benes F.M., and Berretta S. GABAergic interneurons, implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology 25 (2001) 1-27
6. Benes F.M., Lim B., Matzilevich D., Walsh J.P., Subburaju S., and Minns M. Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc. Natl. Acad. Sci. USA. 104 (2007) 10164-10169
7. Bernstein H.G., Baumann B., Danos P., Diekmann S., Bogerts B., Gundelfinger E.D., and Braunewell K.H. Regional and cellular distribution of neural visinin-like protein immunoreactivities (VILIP-1 and VILIP-3) in human brain. J. Neurocytol. 28 (1999) 655-662
8. Bernstein H.G., Braunewell K.H., Spilker C., Danos P., Baumann B., Funke S., Diekmann S., Gundelfinger E.D., and Bogerts B. Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia. Neuroreport 13 (2002) 393-396
9. Bernstein H.G., Becker A., Keilhoff G., Spilker C., Gorczyca W.A., Braunewell K.H., and Grecksch G. Brain region-specific changes in the expression of calcium sensor proteins after repeated applications of ketamine to rats. Neurosci. Lett. 339 (2003) 95-98
10. Brackmann M., Zhao C., Kuhl D., Manahan-Vaughan D., and Braunewell K.H. MGluRs regulate the expression of neuronal calcium sensor proteins NCS-1 and VILIP-1 and the immediate early gene arg3.1/arc in the hippocampus in vivo. Biochem. Biophys. Res. Commun. 322 (2004) 1073-1079
11. Braga M.F., Pereira E.F., Mike A., and Albuquerque E.X. Pb2+via protein kinase C inhibits nicotinic cholinergic modulation of synaptic transmission in the hippocampus. J. Pharmacol. Exp. Ther. 311 (2004) 700-710
12. 2+-sensor proteins, from Alzheimer's disease to cancer. Trends. Pharmacol. Sci. 26 (2005) 345-351
13. Braunewell K.H., Brackmann M., and Manahan-Vaughan D. Group I mGluRs regulate the expression of the intracellular neuronal calcium sensor protein VILIP-1 in vitro and in vivo, possible implications for mGluR-dependent hippocampal plasticity?. Neuropharmacology 44 (2003) 707-715
14. Bulayeva K.B., Glatt S.J., Bulayev O.A., Pavlova T.A., and Tsuang M.T. Genome-wide linkage scan of schizophrenia: a cross-isolate study. Genomics 89 (2007) 167-177
15. Couey J.J., Meredith R.M., Spijker S., Poorthuis R.B., Smit A.B., Brussaard A.B., and Mansvelder H.D. Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex. Neuron. 54 (2007) 73-87
16. De Luca V., Voineskos S., Wong G., and Kennedy J.L. Genetic interaction between alpha4 and beta2 subunits of high affinity nicotinic receptor, analysis in schizophrenia. Exp. Brain. Res. 174 (2006) 292-296
17. Eastwood S.L., and Harrison P.J. Decreased expression of vesicular glutamate transporter 1 and complexin II mRNAs in schizophrenia, further evidence for a synaptic pathology affecting glutamate neurons. Schizophr. Res. 73 (2005) 159-172
18. Egan M.F., and Weinberger D.R. Neurobiology of schizophrenia. Curr. Opin. Neurobiol. 7 (1997) 701-707
19. Ferraguti F., Conquet F., Corti C., Grandes P., Kuhn R., and Knopfel T. Immunohistochemical localization of the mGluR1beta metabotropic glutamate receptor in the adult rodent forebrain, evidence for a differential distribution of mGluR1 splice variants. J. Comp. Neurol. 400 (1998) 391-407
20. Ferraguti F., Cobden P., Pollard M., Cope D., Shigemoto R., Watanabe M., and Somogyi P. Immunolocalization of metabotropic glutamate receptor 1alpha (mGluR1alpha) in distinct classes of interneuron in the CA1 region of the rat hippocampus. Hippocampus 14 (2004) 193-215
21. Freund T.F., and Buzsaki G. Interneurons of the hippocampus. Hippocampus 6 (1996) 347-470
22. Gisabella B., Bolshakov V.Y., and Benes F.M. Regulation of synaptic plasticity in a schizophrenia model. Proc. Natl. Acad. Sci. USA. 102 (2005) 13301-13306
23. Gupta D.S., McCullumsmith R.E., Beneyto M., Haroutunian V., Davis K.L., and Meador-Woodruff J.H. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse 57 (2005) 123-131
24. Harrison P.J. The hippocampus in schizophrenia, a review of the neuropathological evidence and its pathophysiological implications. Psychopharmacology. (Berl). 174 (2004) 151-162
25. Harrison P.J., and Eastwood S.L. Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia. Hippocampus 11 (2001) 508-519
26. Harrison P.J., and Owen M.J. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 361 (2003) 417-419
27. Harrison P.J., and Weinberger D.R. Schizophrenia genes, gene expression, and neuropathology, on the matter of their convergence. Mol. Psychiatry. 10 (2005) 40-68
28. Heckers S. Neuroimaging studies of the hippocampus in schizophrenia. Hippocampus 11 (2001) 520-528
29. Heckers S., Rauch S.L., Goff D., Savage C.R., Schacter D.L., Fischman A.J., and Alpert N.M. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nat. Neurosci. 1 (1998) 318-323
30. Hogg R.C., Raggenbass M., and Bertrand D. Nicotinic acetylcholine receptors, from structure to brain function. Rev. Physiol. Biochem. Pharmacol. 147 (2003) 1-46
31. Homayoun H., and Moghaddam B. NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J. Neurosci. 27 (2007) 11496-11500
32. Javitt D.C., Spencer K.M., Thaker G.K., Winterer G., and Hajós M. Neurophysiological biomarkers for drug development in schizophrenia. Nat. Rev. Drug. Discov. 7 (2008) 68-83
33. Katona I., Acsady L., and Freund T.F. Postsynaptic targets of somatostatin-immunoreactive interneurons in the rat hippocampus. Neuroscience 88 (1999) 37-55
34. Kingston A.E., Burnett J.P., Mayne N.G., and Lodge D. Pharmacological analysis of 4-carboxyphenylglycine derivatives, comparison of effects on mGluR1 alpha and mGluR5a subtypes. Neuropharmacology 34 (1995) 887-894
35. Lapointe V., Morin F., Ratte S., Croce A., Conquet F., and Lacaille J.C. Synapse-specific mGluR1-dependent long-term potentiation in interneurones regulates mouse hippocampal inhibition. J. Physiol. 555 (2004) 125-135
36. Lewis D.A., and Levitt P. Schizophrenia as a disorder of neurodevelopment. Annu. Rev. Neurosci. 25 (2002) 409-432
37. Lin L., Jeanclos E.M., Treuil M., Braunewell K.H., Gundelfinger E.D., and Anand R. The calcium sensor protein visinin-like protein-1 modulates the surface expression and agonist sensitivity of the alpha 4beta 2 nicotinic acetylcholine receptor. J. Biol. Chem. 277 (2002) 41872-41878
38. Lujan R., Nusser Z., Roberts J.D., Shigemoto R., and Somogyi P. Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus. Eur. J. Neurosci. 8 (1996) 1488-1500
39. Lujan R., Roberts J.D., Shigemoto R., Ohishi H., and Somogyi P. Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites. J. Chem. Neuroanat. 13 (1997) 219-241
40. Manahan-Vaughan D., and Braunewell K.H. The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity. Cereb. Cortex. 15 (2005) 1703-1713
41. Miklos G.L., and Maleszka R. Microarray reality checks in the context of a complex disease. Nat. Biotechnol. 22 (2004) 615-621
42. Moghaddam B. Targeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia. Psychopharmacology. (Berl). 174 (2004) 39-44
43. Mohn A.R., Gainetdinov R.R., Caron M.G., and Koller B.H. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98 (1999) 427-436
44. Naie K., and Manahan-Vaughan D. Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-d-aspartate and metabotropic glutamate receptor-dependent mechanisms. Eur. J. Neurosci. 21 (2005) 411-421
45. Nashmi R., Xiao C., Deshpande P., McKinney S., Grady S.R., Whiteaker P., Huang Q., McClure-Begley T., Lindstrom J.M., Labarca C., Collins A.C., Marks M.J., and Lester H.A. Chronic nicotine cell specifically upregulates functional alpha4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. J. Neurosci. 27 (2007) 8202-8218
46. Olney J.W., and Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry. 52 (1995) 998-1007
47. Olney J.W., Labruyere J., Wang G., Wozniak D.F., Price M.T., and Sesma M.A. NMDA antagonist neurotoxicity, mechanism and prevention. Science 254 (1991) 1515-1518
48. Olney J.W., Newcomer J.W., and Farber N.B. NMDA receptor hypofunction model of schizophrenia. J. Psychiatr. Res. 33 (1999) 523-533
49. Perez Y., Morin F., and Lacaille J.C. A hebbian form of long-term potentiation dependent on mGluR1a in hippocampal inhibitory interneurons. Proc. Natl. Acad. Sci. USA. 98 (2001) 9401-9406
50. Reynolds G.P., and Harte M.K. The neuronal pathology of schizophrenia, molecules and mechanisms. Biochem. Soc. Trans. 35 (2007) 433-436
51. Shigemoto R., Kinoshita A., Wada E., Nomura S., Ohishi H., Takada M., Flor P.J., Neki A., Abe T., Nakanishi S., and Mizuno N. Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus. J. Neurosci. 17 (1997) 7503-7522
52. Spilker C., Dresbach T., and Braunewell K.H. Reversible translocation and activity-dependent localization of the calcium-myristoyl switch protein VILIP-1 to different membrane compartments in living hippocampal neurons. J. Neurosci. 22 (2002) 7331-7339
53. Tebartz van Elst L., Valerius G., Buchert M., Thiel T., Rusch N., Bubl E., Hennig J., Ebert D., and Olbrich H.M. Increased prefrontal and hippocampal glutamate concentration in schizophrenia, evidence from a magnetic resonance spectroscopy study. Biol. Psychiatr. 58 (2005) 724-730
54. van Hooft J.A., Giuffrida R., Blatow M., and Monyer H. Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons. J. Neurosci. 20 (2000) 3544-3551
55. Vercauteren F.G.G., Flores G., Ma W., Chabot J.-G., Geenen L., Clerens S., Fazel A., Bergeron J.J.M., Srivastava L.K., Arckens L., and Quirion R. An organelle proteomic method to study neurotransmission-related proteins, applied to a neurodevelopmental model of schizophrenia. Proteomics 7 (2007) 3569-3579
56. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry. 44 (1987) 660-669
57. Winterer G., Musso F., Konrad A., Vucurevic G., Stoeter P., Sander T., and Gallinat J. Association of attentional network function with exon 5 variations of the CHRNA4 gene. Hum. Mol. Genet. 16 (2007) 2165-2174
58. Zhang Z.J., and Reynolds G.P. A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia. Schizophr. Res. 55 (2002) 1-10
59. Zhao C., and Braunewell K.H. Expression of the neuronal calcium sensor visinin-like protein-1 in the rat hippocampus. Neuroscience 153 (2008) 1202-1212