Human mesenchymal stromal cells express CD14 cross-reactive epitopes

Cytometry Part A

Volumn 79 A, Issue 8, 2011, Pages 635-645

  Pilz, Gregor A ^a   Braun, Julian ^a   Ulrich, Christine ^a   Felka, Tino ^a   Warstat, Katrin ^a   Ruh, Manuel ^a   Schewe, Bernhard ^b   Abele, Harald ^a   Larbi, Anis ^c   Aicher, Wilhelm K ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b Berufsgenossenschaftlichen Unfallklinik Tubingen   (Germany)

^c AGENCY FOR SCIENCE   (Singapore)

Author keywords

CD14; Cell surface antigen; Mesenchymal stromal cells; Monocytes

Indexed keywords

EID: 79960612305     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.21073     Document Type: Article

References (47)

1. Jones E, McGonagle D. Human bone marrow mesenchymal stem cells in vivo. Rheumatology 2008; 47: 126-131.
2. Phinney DG, Prockop DJ. Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair-Current views. Stem Cells 2007; 25: 2896-2902.
3. Hristov M, Erl W, Weber PC. Endothelial progenitor cells: Mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol 2003; 23: 1185-1189.
4. Vogel W, Grünebach F, Messam CA, Kanz L, Brugger W, Bühring HJ. Heterogeneity among human bone marrow-derived mesenchymal stem cells and neural progenitor cells. Haematologica 2003; 88: 126-133.
5. Pozzobon M, Piccoli M, Ditadi A, Bollini S, Destro R, Andre-Schmutz I, Masiero L, Lenzini E, Zanesco L, Petrelli L, Cavazzana-Calvo M, Gazzola MV, De Coppi P. Mesenchymal stromal cells can be derived from bone marrow CD133+ cells: Implications for therapy. Stem Cells Dev 2009; 18: 497-510.
6. Dominici M, Le Blanc K, Müller I, Slaper-Cortenbach I, Marini FC, Krause DS, Deans RJ, Keating A, Prockop DJ, Horwitz EM. Minimal criteria for defining multipotent mesenchymal stromal cells.The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8: 315-317.
7. Horwitz EM, Le Blanc K, Dominici M, Müller I, Slaper-Cortenbach I, Marini FC, Deans RJ, Krause DS, Keating A. Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy 2005; 7: 393-395.
8. Parolini O, Alviano F, Bagnara GP, Bilic G, Buhring HJ, Evangelista M, Hennerbichler S, Liu B, Magatti M, Mao N, et al. Concise review: Isolation and characterization of cells from human term placenta: Outcome of the First International Workshop on Placenta Derived Stem Cells. Stem Cells 2008; 26: 300-311.
9. Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001; 13: 85-94.
10. Mitchell JB, McIntosh K, Zvonic S, Garrett S, Floyd ZE, Kloster A, Di Halvorsen Y, Storms RW, Goh B, Kilroy G, et al. Immunophenotype of human adipose-derived cells: Temporal changes in stromal-associated and stem cell-associated markers. Stem Cells 2006; 24: 376-385.
11. Braun J, Hack A, Weis-Klemm M, Conrad S, Treml S, Kohler K, Walliser U, Skutella T, Aicher WK. Evaluation of the osteogenic and chondrogenic differentiation capacities of equine adipose tissue-derived mesenchymal stem cells. Am J Vet Res 2010; 71: 1228-1236.
12. Jersmann HPA, Hii CST, Hodge GL, Ferrante A. Synthesis and surface expression of CD14 by human endothelial cells. Infect Immun 2001; 69: 479-485.
13. Opitz CA, Litzenburger UM, Lutz C, Lanz T, Tritschler I, Köppel A, Tolosa E, Hoberg M, Anderl A, Aicher WK, Weller M, Wick W, Platten M. Toll-like receptors enhance the immunosuppreddive properties of human MSC by inducing indoleamine-2, 3-dioxygenase-1 via interferin-β and proteinkinase-R. Stem Cells 2009; 27: 909-919.
14. Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM, Vogel SN. CD11b/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. J Immunology 2001; 166: 574-581.
15. Felka T, Schäfer R, deZwart P, Aicher WK. Animal serum-free differentiation of human mesenchymal stem cells. Cytotherapy 2010; 12: 143-153.
16. Felka T, Schäfer R, Schewe B, Benz K, Aicher WK. Hypoxia reduces the inhibitpry effect of IL-1beta on chondrogenic differentiation of FCS-free expanded MSC. Osteoarthritis Cartilage 2009; 17: 1368-1376.
17. Muller I, Kordowich S, Holzwarth C, Spano C, Isensee G, Staiber A, Viebahn S, Gieseke F, Langer H, Gawaz MP, Horwitz EM, Conte P, Handgretinger R, Dominici M. Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM. Cytotherapy 2006; 8: 437-444.
18. Perfetto SP, Chattopadhyay PK, Lamoreaux L, Nguyen R, Ambrozak D, Koup RA, Roederer M. Amine reactive dyes: An effective tool to discriminate live and dead cells in polychromatic flow cytometry. J Immunol Methods 2006; 313: 199-208.
19. Apel A, Groth A, Schlesinger S, Bruns H, Schemmer P, Buchler MW, Herr I. Suitability of human mesenchymal stem cells for gene therapy depends on the expansion medium. Exp Cell Res 2009; 315: 498-507.
20. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis.Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 1995; 184: 39-51.
21. Schmid I, Krall WJ, Uittenbogaart CH, Braun J, Giorgi JV. Dead cell discrimination with 7-amino-actinomycin D in combination with dual color immunofluorescence in single laser flow cytometry. Cytometry 1992; 13: 204-208.
22. Herzenberg LA, Tung J, Moore WA, Herzenberg LA, Parks DR. Interpreting flow cytometry data: A guide for the perplexed. Nat Immunol 2006; 7: 681-685.
23. Hoberg M, Rudert M, Pap T, Klein G, Gay S, Aicher WK. Attachment to laminin-111 facilitates transforming growth factor beta-induced expression of matrix metalloproteinase-3 in synovial fibroblasts. Ann Rheum Dis 2007; 66: 446-451.
24. Rasmussen R, Morrison T, Herrmann M, Wittwer C. Quantitative PCR by continuous fluorescence monitoring of a double strand DNA specific binding dye. Biochemica 1998; 2: 8-11.
25. Alexander D, Judex M, Meyringer R, Weis-Klemm M, Gay S, Muller-Ladner U, Aicher WK. Transcription factor Egr-1 activates collagen expression in immortalized fibroblasts or fibrosarcoma cells. Biol Chem 2002; 383: 1845-1853.
26. Ausubel F, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors. Short Protocols in Molecular Biology, 2nd ed. New York: Wiley; 1992.
27. Goyert SM. Protein reviews on the Web. Available at: 1999.
28. Bazil V, Baudys M, Hilgert I, Stefanov I, Low MG, Zbrozek J, HorejsÌ VC. Structural relationship between the soluble and membrane-bound forms of human monocyte surface glycoprotein CD 14. Mol Immunol 1989; 26: 657-662.
29. Sacchetti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, Saggio I, Tagliafico E, Ferrari S, Robey PG, Riminucci M, Bianco P. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007; 131: 324-336.
30. Battula VL, Treml S, Bareiss PM, Gieseke F, Roelofs H, de Zwart P, Müller I, Schewe B, Skutella T, Fibbe WE, Kanz L, Buhring HJ. Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271 and mesenchymal stem cell antigen-1 (MSCA-1). Haematologica 2009; 94: 19-30.
31. Bühring HJ, Battula VL, Treml S, Schewe B, Kanz L, Vogel W. Novel markers for the prospective isolation of human MSC. Ann N Y Acad Sci 2007; 1106: 262-271.
32. De Bari C, Dell'Accio F, Tylzanowski P, Luyten FP. Multipotent mesenchymal stem cells from adult synovial membrane. Arthritis Rheum 2001; 44: 1928-1942.
33. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: Implications for cell-based therapies. Tissue Eng 2001; 7: 211-228.
34. Jones EA, Crawford A, English A, Henshaw K, Mundy J, Corscadden D, Chapman T, Emery P, Hatton P, McGonagle D. Synovial fluid mesenchymal stem cells in health and early osteoarthritis: Detection and functional evaluation at the single-cell level. Arthritis Rheum 2008; 58: 1731-1740.
35. Tarnok A, Ulrich H, Bocsi J. Phenotypes of stem cells from diverse origin. Cytometry Part A 2010; 77A: 6-10.
36. Zimmerlin L, Donnenberg VS, Pfeifer ME, Meyer ME, Peault B, Rubin PJ, Donnenberg AD. Stromal vascular progenitors in adult human adipose tissue. Cytometry Part A 2010; 77A: 22-30.
37. Porretti LAC, Colombo F, Lopa R, Rossi G, Mazzaferro V, Battiston C, Svegliati-Baroni GFB, Rebulla P, Prati D. Simultaneous characterization of progenitor cell compartments in adult human liver. Cytometry Part A 2010; 77A: 31-40.
38. Pilz GA, Abele H, Braun J, Felka T, Warstat K, Bühring HJ, Schäfer R, Aicher WK. Human term placenta-derived mesenchymal stromal cells (MSC) are less prone to osteogenic differentiation when compared to bone marrow-derived MSC. Stem Cells Dev 2011; 20: 635-646.
39. McIntosh K, Zvonic S, Garrett S, Mitchell JB, Floyd ZE, Hammill L, Kloster A, Di Halvorsen Y, Ting JP, Storms RW, Goh B, Kilroy G, Wu X, Gimble JM. The immunogenicity of human adipose-derived cells: Temporal changes in vitro. Stem Cells 2006; 24: 1246-1253.
40. Colter DC, Class R, DiGirolamo CM, Prockop DJ. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc Natl Acad Sci U S A 2000; 97: 3213-3218.
41. Herrmann F, Komischke B, Odenwald E, Ludwig WD. Use of monoclonal antibodies as diagnostic tool in human acute leukmia. Blut 1983; 47: 157-163.
42. Barry F, Boynton R, Murphy M, Zaia J. The SH-3 and SH-4 antibodies recognize distinct epitopes on CD73 from human mesenchymal stem cells. Biochem Biophys Res Commun 2001; 289: 519-524.
43. Moos V, Fickert S, Muller B, Weber U, Sieper J. Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage. J Rheumatol 1999; 26: 870-879.
44. Kuwana M, Okazaki Y, Kodama H, Izumi K, Yasuoka H, Ogawa Y, Kawakami Y, Ikeda Y. Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation. J Leukoc Biol 2003; 74: 833-845.
45. Kodama H, Inoue T, Watanabe R, Yasuoka H, Kawakami Y, Ogawa S, Ikeda Y, Mikoshiba K, Kuwana M. Cardiomyogenic potential of mesenchymal progenitors derived from human circulating CD14+ monocytes. Stem Cells Dev 2005; 14: 676-686.
46. Kodama H, Inoue T, Watanabe R, Yasutomi D, Kawakami Y, Ogawa S, Mikoshiba K, Ikeda Y, Kuwana M. Neurogenic potential of progenitors derived from human circulating CD14+ monocytes. Immunol Cell Biol 2006; 84: 209-217.
47. Raghunath J, Sutherland J, Salih V, Mordan N, Butler PE, Seifalian AM. Chondrogenic potential of blood-acquired mesenchymal progenitor cells. J Plast Reconstr Aesthet Surg 2010; 63: 841-847.