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Volumn 12, Issue 2, 2010, Pages 143-153

Animal serum-free expansion and differentiation of human mesenchymal stromal cells

Author keywords

Fetal calf serum free differentiation; Fetal calf serum free expansion; Mesenchymal stromal cells

Indexed keywords

COLLAGEN TYPE 2; LIPOPROTEIN LIPASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; PROTEOGLYCAN;

EID: 77749273886     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653240903470647     Document Type: Article
Times cited : (51)

References (40)
  • 2
    • 27944435821 scopus 로고    scopus 로고
    • Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement
    • Horwitz EM, Le Blanc K, Dominici M, Mueller I, Slaper-Cortenbach I, Marini FC, et al. Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy. 2005;7: 393-5.
    • (2005) Cytotherapy , vol.7 , pp. 393-395
    • Horwitz, E.M.1    Le Blanc, K.2    Dominici, M.3    Mueller, I.4    Slaper-Cortenbach, I.5    Marini, F.C.6
  • 3
    • 33845999239 scopus 로고    scopus 로고
    • N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible
    • Heiskanen A, Satomaa T, Tiitinen S, Laitinen A, Mannelin S, Impola U, et al. N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible. Stem Cells. 2007;25:197-202.
    • (2007) Stem Cells , vol.25 , pp. 197-202
    • Heiskanen, A.1    Satomaa, T.2    Tiitinen, S.3    Laitinen, A.4    Mannelin, S.5    Impola, U.6
  • 4
    • 0036376741 scopus 로고    scopus 로고
    • Immune response to fetal calf serum by two adenosine deaminase-deficient patients after T cell gene therapy
    • Tuschong L, Soenen SL, Blaese RM, Candotti F, Muul LM. Immune response to fetal calf serum by two adenosine deaminase-deficient patients after T cell gene therapy. Hum Gene Ther. 2002;13:1605-10.
    • (2002) Hum Gene Ther , vol.13 , pp. 1605-1610
    • Tuschong, L.1    Soenen, S.L.2    Blaese, R.M.3    Candotti, F.4    Muul, L.M.5
  • 5
    • 33750081777 scopus 로고    scopus 로고
    • FDA regulation of stem-cell-based therapies
    • Halme DG, Kessler DA. FDA regulation of stem-cell-based therapies. N Engl J Med. 2006;355:1730-5.
    • (2006) N Engl J Med , vol.355 , pp. 1730-1735
    • Halme, D.G.1    Kessler, D.A.2
  • 6
    • 0031407119 scopus 로고    scopus 로고
    • Medicinal and other products and human and animal transmissible spongiform encephalopathies: Memorandum from a WHO meeting
    • Medicinal and other products and human and animal transmissible spongiform encephalopathies: memorandum from a WHO meeting. Bull World Health Organ. 1997;75:505-13.
    • (1997) Bull World Health Organ , vol.75 , pp. 505-513
  • 7
    • 34547162587 scopus 로고    scopus 로고
    • Concise review. No breakthroughs for human mesenchymal and embryonic stem cell culture: Conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serumfree, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold!
    • Mannello F, Tonti GA. Concise review. No breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serumfree, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! Stem Cells. 2007; 25:1603-9.
    • (2007) Stem Cells , vol.25 , pp. 1603-1609
    • Mannello, F.1    Tonti, G.A.2
  • 8
    • 33748304106 scopus 로고    scopus 로고
    • Differences in the effect on neural stem cells of fetal bovine serum in substrate-coated and soluble form
    • Hung CH, Young TH. Differences in the effect on neural stem cells of fetal bovine serum in substrate-coated and soluble form. Biomaterials. 2006;27:5901-8.
    • (2006) Biomaterials , vol.27 , pp. 5901-5908
    • Hung, C.H.1    Young, T.H.2
  • 9
    • 1442308105 scopus 로고    scopus 로고
    • Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes
    • Pochampally RR, Smith JR, Ylostalo J, Prockop DJ. Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes. Blood. 2004;103:1647-52.
    • (2004) Blood , vol.103 , pp. 1647-1652
    • Pochampally, R.R.1    Smith, J.R.2    Ylostalo, J.3    Prockop, D.J.4
  • 10
    • 0028966028 scopus 로고
    • The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro
    • Gronthos S, Simmons PJ. The growth factor requirements of STRO-1-positive human bone marrow stromal precursors under serum-deprived conditions in vitro. Blood. 1995; 85:929-40.
    • (1995) Blood , vol.85 , pp. 929-940
    • Gronthos, S.1    Simmons, P.J.2
  • 11
    • 0030938134 scopus 로고    scopus 로고
    • Factors required for bone marrow stromal fibroblast colony formation in vitro
    • Kuznetsov SA, Friedenstein AJ, Robey PG. Factors required for bone marrow stromal fibroblast colony formation in vitro. Br J Haematol. 1997;97:561-70.
    • (1997) Br J Haematol , vol.97 , pp. 561-570
    • Kuznetsov, S.A.1    Friedenstein, A.J.2    Robey, P.G.3
  • 12
    • 34247602975 scopus 로고    scopus 로고
    • Human AB serum and thrombin-activated platelet-rich plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue
    • Kocaoemer A, Kern S, Kluter H, Bieback K. Human AB serum and thrombin-activated platelet-rich plasma are suitable alternatives to fetal calf serum for the expansion of mesenchymal stem cells from adipose tissue. Stem Cells. 2007;25:1270-8.
    • (2007) Stem Cells , vol.25 , pp. 1270-1278
    • Kocaoemer, A.1    Kern, S.2    Kluter, H.3    Bieback, K.4
  • 13
    • 10044230580 scopus 로고    scopus 로고
    • Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use
    • Stute N, Holtz K, Bubenheim M, Lange C, Blake F, Zander AR. Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol. 2004;32:1212-25.
    • (2004) Exp Hematol , vol.32 , pp. 1212-1225
    • Stute, N.1    Holtz, K.2    Bubenheim, M.3    Lange, C.4    Blake, F.5    Zander, A.R.6
  • 14
    • 33749524824 scopus 로고    scopus 로고
    • Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogenic species-specific serum and administration in fibrin constructs
    • Gregory CA, Reyes E, Whitney MJ, Spees JL. Enhanced engraftment of mesenchymal stem cells in a cutaneous wound model by culture in allogenic species-specific serum and administration in fibrin constructs. Stem Cells. 2006; 24:2232-43.
    • (2006) Stem Cells , vol.24 , pp. 2232-2243
    • Gregory, C.A.1    Reyes, E.2    Whitney, M.J.3    Spees, J.L.4
  • 15
    • 0034722911 scopus 로고    scopus 로고
    • Effect of serum on human bone marrow stromal cells: Ex vivo expansion and in vivo bone formation
    • Kuznetsov SA, Mankani MH, Robey PG. Effect of serum on human bone marrow stromal cells: ex vivo expansion and in vivo bone formation. Transplantation. 2000;70:1780-7.
    • (2000) Transplantation , vol.70 , pp. 1780-1787
    • Kuznetsov, S.A.1    Mankani, M.H.2    Robey, P.G.3
  • 16
    • 33750195530 scopus 로고    scopus 로고
    • Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM
    • Muller I, Kordowich S, Holzwarth C, Spano C, Isensee G, Staiber A, et al. Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM. Cytotherapy. 2006;8:437-44.
    • (2006) Cytotherapy , vol.8 , pp. 437-444
    • Muller, I.1    Kordowich, S.2    Holzwarth, C.3    Spano, C.4    Isensee, G.5    Staiber, A.6
  • 17
    • 64049103301 scopus 로고    scopus 로고
    • Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineering
    • Zaky SH, Ottonello A, Strada P, Cancedda R, Mastrogiacomo M. Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineering. J Tissue Eng Regen Med. 2008;2:472-81.
    • (2008) J Tissue Eng Regen Med , vol.2 , pp. 472-481
    • Zaky, S.H.1    Ottonello, A.2    Strada, P.3    Cancedda, R.4    Mastrogiacomo, M.5
  • 18
    • 0036325209 scopus 로고    scopus 로고
    • Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count
    • Weibrich G, Kleis WK, Hafner G, Hitzler WE. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg. 2002; 30:97-102.
    • (2002) J Craniomaxillofac Surg , vol.30 , pp. 97-102
    • Weibrich, G.1    Kleis, W.K.2    Hafner, G.3    Hitzler, W.E.4
  • 19
    • 64149117096 scopus 로고    scopus 로고
    • Osteogenic potential of platelet-rich plasma combined with cells and artificial bone]
    • Li S, Zhang C, Yuan T. [Osteogenic potential of platelet-rich plasma combined with cells and artificial bone]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007;21:58-64.
    • (2007) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.21 , pp. 58-64
    • Li, S.1    Zhang, C.2    Yuan, T.3
  • 20
    • 0024848785 scopus 로고
    • The potential role of platelet-derived growth factor as an autocrine or paracrine factor for human bone cells
    • Graves DT, Valentin-Opran A, Delgado R, Valente AJ, Mundy G, Piche J. The potential role of platelet-derived growth factor as an autocrine or paracrine factor for human bone cells. Connect Tissue Res. 1989;23:209-18.
    • (1989) Connect Tissue Res , vol.23 , pp. 209-218
    • Graves, D.T.1    Valentin-Opran, A.2    Delgado, R.3    Valente, A.J.4    Mundy, G.5    Piche, J.6
  • 21
  • 22
    • 34047129218 scopus 로고    scopus 로고
    • Controlled release of PRP-derived growth factors promotes osteogenic differentiation of human mesenchymal stem cells
    • Lin SS, Landesberg R, Chin HS, Lin J, Eisig SB, Lu HH. Controlled release of PRP-derived growth factors promotes osteogenic differentiation of human mesenchymal stem cells. Conf Proc IEEE Eng Med Biol Soc. 2006;1:4358-61.
    • (2006) Conf Proc IEEE Eng Med Biol Soc , vol.1 , pp. 4358-4361
    • Lin, S.S.1    Landesberg, R.2    Chin, H.S.3    Lin, J.4    Eisig, S.B.5    Lu, H.H.6
  • 23
    • 58149398565 scopus 로고    scopus 로고
    • Platelet-rich concentrate supports human mesenchymal stem cell proliferation, bone morphogenetic protein-2 messenger RNA expression, alkaline phosphatase activity, and bone formation in vitro: A mode of action to enhance bone repair
    • Parsons P, Butcher A, Hesselden K, Ellis K, Maughan J, Milner R, et al. Platelet-rich concentrate supports human mesenchymal stem cell proliferation, bone morphogenetic protein-2 messenger RNA expression, alkaline phosphatase activity, and bone formation in vitro: a mode of action to enhance bone repair. J Orthop Trauma. 2008;22:595-604.
    • (2008) J Orthop Trauma , vol.22 , pp. 595-604
    • Parsons, P.1    Butcher, A.2    Hesselden, K.3    Ellis, K.4    Maughan, J.5    Milner, R.6
  • 24
    • 0345768562 scopus 로고    scopus 로고
    • Influence of platelet-rich plasma (PRP) on osteogenic differentiation of rat bone marrow stromal cells. An in vitro study
    • Arpornmaeklong P, Kochel M, Depprich R, Kubler NR, Wurzler KK. Influence of platelet-rich plasma (PRP) on osteogenic differentiation of rat bone marrow stromal cells. An in vitro study. Int J Oral Maxillofac Surg. 2004;33: 60-70.
    • (2004) Int J Oral Maxillofac Surg , vol.33 , pp. 60-70
    • Arpornmaeklong, P.1    Kochel, M.2    Depprich, R.3    Kubler, N.R.4    Wurzler, K.K.5
  • 25
    • 1442290154 scopus 로고    scopus 로고
    • Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions
    • Gruber R, Karreth F, Kandler B, Fuerst G, Rot A, Fischer MB, et al. Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets. 2004;15:29-35.
    • (2004) Platelets , vol.15 , pp. 29-35
    • Gruber, R.1    Karreth, F.2    Kandler, B.3    Fuerst, G.4    Rot, A.5    Fischer, M.B.6
  • 26
    • 39749185584 scopus 로고    scopus 로고
    • The use of mesenchymal stem cells for chondrogenesis
    • Pelttari K, Steck E, Richter W. The use of mesenchymal stem cells for chondrogenesis. Injury. 2008;39 (Suppl 1): S58-65.
    • (2008) Injury , vol.39 , Issue.SUPPL. 1
    • Pelttari, K.1    Steck, E.2    Richter, W.3
  • 27
    • 64449087717 scopus 로고    scopus 로고
    • Influence of platelet-rich plasma on chondrogenic differentiation and proliferation of chondrocytes and mesenchymal stem cells
    • Drengk A, Zapf A, Sturmer EK, Sturmer KM, Frosch KH. Influence of platelet-rich plasma on chondrogenic differentiation and proliferation of chondrocytes and mesenchymal stem cells. Cells Tissues Organs. 2009;189:317-26.
    • (2009) Cells Tissues Organs , vol.189 , pp. 317-326
    • Drengk, A.1    Zapf, A.2    Sturmer, E.K.3    Sturmer, K.M.4    Frosch, K.H.5
  • 28
    • 0020699974 scopus 로고
    • Effect of hormones and growth factors on alkaline phosphatase activity and collagen synthesis in cultured rat calvariae
    • Canalis E. Effect of hormones and growth factors on alkaline phosphatase activity and collagen synthesis in cultured rat calvariae. Metabolism. 1983;32:14-20.
    • (1983) Metabolism , vol.32 , pp. 14-20
    • Canalis, E.1
  • 29
    • 47149097280 scopus 로고    scopus 로고
    • Characterization and functional analysis of osteoblast-derived fibulins in the human hematopoietic stem cell niche
    • Hergeth SP, Aicher WK, Essl M, Schreiber TD, Sasaki T, Klein G. Characterization and functional analysis of osteoblast-derived fibulins in the human hematopoietic stem cell niche. Exp Hematol. 2008;36:1022-34.
    • (2008) Exp Hematol , vol.36 , pp. 1022-1034
    • Hergeth, S.P.1    Aicher, W.K.2    Essl, M.3    Schreiber, T.D.4    Sasaki, T.5    Klein, G.6
  • 30
    • 33747713246 scopus 로고    scopus 로고
    • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
    • Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini F, Krause D, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315-7.
    • (2006) Cytotherapy , vol.8 , pp. 315-317
    • Dominici, M.1    Le Blanc, K.2    Mueller, I.3    Slaper-Cortenbach, I.4    Marini, F.5    Krause, D.6
  • 31
    • 0002436838 scopus 로고    scopus 로고
    • Quantitative PCR by continuous fluorescence monitoring of a double strand DNA specific binding dye
    • Rasmussen RMT, Herrmann M, Wittwer C. Quantitative PCR by continuous fluorescence monitoring of a double strand DNA specific binding dye. Biochemica. 1998; 2:8-11.
    • (1998) Biochemica , vol.2 , pp. 8-11
    • Rasmussen, R.M.T.1    Herrmann, M.2    Wittwer, C.3
  • 32
    • 70349233954 scopus 로고    scopus 로고
    • Hypoxia reduces the inhibitory effect of IL-1beta on chondrogenic differentiation of FCS-free expanded MSC
    • Felka T, Schafer R, Schewe B, Benz K, Aicher WK. Hypoxia reduces the inhibitory effect of IL-1beta on chondrogenic differentiation of FCS-free expanded MSC. Osteoarthritis Cartilage. 2009;17:1368-76.
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 1368-1376
    • Felka, T.1    Schafer, R.2    Schewe, B.3    Benz, K.4    Aicher, W.K.5
  • 33
    • 47649121002 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): Transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages
    • Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U, et al. PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages. Blood. 2008;112:295-307.
    • (2008) Blood , vol.112 , pp. 295-307
    • Ng, F.1    Boucher, S.2    Koh, S.3    Sastry, K.S.4    Chase, L.5    Lakshmipathy, U.6
  • 34
    • 0028001051 scopus 로고
    • Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture
    • Petruschke T, Rohrig K, Hauner H. Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture. Int J Obes Relat Metab Disord. 1994;18:532-6.
    • (1994) Int J Obes Relat Metab Disord , vol.18 , pp. 532-536
    • Petruschke, T.1    Rohrig, K.2    Hauner, H.3
  • 35
    • 67651018945 scopus 로고    scopus 로고
    • IKKbeta and the antiadipogenic effect of platelet-derived growth factor in human abdominal subcutaneous preadipocytes
    • Gagnon A, Landry A, Sorisky A. IKKbeta and the antiadipogenic effect of platelet-derived growth factor in human abdominal subcutaneous preadipocytes. J Endocrinol. 2009;201:75-80.
    • (2009) J Endocrinol , vol.201 , pp. 75-80
    • Gagnon, A.1    Landry, A.2    Sorisky, A.3
  • 36
    • 0022545228 scopus 로고
    • Adipogenic factors in human serum promote the adipose conversion of 3T3-L1 fibroblasts
    • Hauner H, Loffler G. Adipogenic factors in human serum promote the adipose conversion of 3T3-L1 fibroblasts. Int J Obes. 1986;10:323-30.
    • (1986) Int J Obes , vol.10 , pp. 323-330
    • Hauner, H.1    Loffler, G.2
  • 37
    • 67349275662 scopus 로고    scopus 로고
    • Platelet-rich plasma and fibrin glue-coated bioactive ceramics enhance growth and differentiation of goat bone marrow-derived stem cells
    • Part A
    • Nair MB, Varma HK, John A. Platelet-rich plasma and fibrin glue-coated bioactive ceramics enhance growth and differentiation of goat bone marrow-derived stem cells. Tissue Eng Part A. 2008;158:555-72.
    • (2008) Tissue Eng , vol.158 , pp. 555-572
    • Nair, M.B.1    Varma, H.K.2    John, A.3
  • 38
    • 0030705161 scopus 로고    scopus 로고
    • Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures
    • Oreffo RO, Virdi AS, Triffitt JT. Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures. Eur J Cell Biol. 1997;74:251-61.
    • (1997) Eur J Cell Biol , vol.74 , pp. 251-261
    • Oreffo, R.O.1    Virdi, A.S.2    Triffitt, J.T.3
  • 39
    • 40749127640 scopus 로고    scopus 로고
    • In vitro proliferation and differentiation of human mesenchymal stem cells cultured in autologous plasma derived from bone marrow
    • Part A
    • Sun X, Gan Y, Tang T, Zhang X, Dai K. In vitro proliferation and differentiation of human mesenchymal stem cells cultured in autologous plasma derived from bone marrow. Tissue Eng Part A. 2008;14:391-400.
    • (2008) Tissue Eng , vol.14 , pp. 391-400
    • Sun, X.1    Gan, Y.2    Tang, T.3    Zhang, X.4    Dai, K.5
  • 40
    • 2342613539 scopus 로고    scopus 로고
    • Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications
    • Nuttall ME, Gimble JM. Controlling the balance between osteoblastogenesis and adipogenesis and the consequent therapeutic implications. Curr Opin Pharmacol. 2004;4:290-4.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 290-294
    • Nuttall, M.E.1    Gimble, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.