Pathogenesis of implant-associated infection: The role of the host

Seminars in Immunopathology

Volumn 33, Issue 3, 2011, Pages 295-306

  Zimmerli, Werner ^a   Sendi, Parham ^b  

^a Kantonsspital Liestal   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Acquired immune defect; Biocompatibility; Biofilm; Implant associated infection; Neointima

Indexed keywords

BIOMATERIAL; DACRON; POLITEF; STAINLESS STEEL; TITANIUM;

BACTERIUM ADHERENCE; BIOCOMPATIBILITY; BONE NAIL; BONE PLATE; BONE SCREW; CHLAMYDIA; COMPLEMENT SYSTEM; COXIELLA BURNETII; DACRON VASCULAR PROSTHESIS; DEGRANULATION; DEVICE INFECTION; ENDOPROSTHESIS LOOSENING; ESCHERICHIA COLI; FOREIGN BODY REACTION; GRANULOCYTE; HEART VALVE PROSTHESIS; HOST RESISTANCE; HUMAN; IMPLANT; INFECTION SENSITIVITY; JOINT PROSTHESIS; LISTERIA; MECHANICAL STRESS; MYCOBACTERIUM; NANOTECHNOLOGY; NONHUMAN; PATHOGENESIS; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PROSTHESIS FAILURE; PROSTHESIS INFECTION; PSEUDOMONAS; REVIEW; RICKETTSIA; SALMONELLA; SHIGELLA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; WOUND HEALING;

ANIMALS; BACTERIAL ADHESION; BIOCOMPATIBLE MATERIALS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; NEOINTIMA; PHAGOCYTOSIS; PROSTHESES AND IMPLANTS; PROSTHESIS-RELATED INFECTIONS;

EID: 79960562549     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-011-0275-7     Document Type: Review

References (149)

1. Darouiche RO (2004) Treatment of infections associated with surgical implants. N Engl J Med 350:1422-1429 (Pubitemid 38419996)
2. Coady MA, Ikonomidis JS, Cheung AT, Matsumoto AH, Dake MD, Chaikof EL, Cambria RP, Mora-Mangano CT, Sundt TM, Sellke FW (2010) Surgical management of descending thoracic aortic disease: open and endovascular approaches: a scientific statement from the American Heart Association. Circulation 121:2780-2804
3. Peng HT (2010) Thromboelastographic study of biomaterials. J Biomed Mater Res B Appl Biomater 94:469-485
4. Williams DF (2009) On the nature of biomaterials. Biomaterials 30:5897-5909
5. Lendlein A, Behl M, Hiebl B, Wischke C (2010) Shape-memory polymers as a technology platform for biomedical applications. Expert Rev Med Devices 7:357-379
6. Anderson JM (2011) Biocompatibility of implants: lymphocyte/ macrophage interactions. Semin Immunopathol (this issue)
7. Baier RE (2006) Surface behaviour of biomaterials: the theta surface for biocompatibility. J Mater Sci Mater Med 17:1057-1062 (Pubitemid 44835992)
8. Steckelberg J, Osmon D In: Waldvogel FA, Bisno AL, eds. Infections associated with indwelling medical devices. 3rd ed. Washington, D.C.: American Society for Microbiology, 2000: 173-209
9. Zimmerli W, Trampuz A, Ochsner PE (2004) Prosthetic-joint infections. N Engl J Med 351:1645-1654
10. Del Pozo JL, Patel R (2009) Clinical practice. Infection associated with prosthetic joints. N Engl J Med 361:787-794
11. Tleyjeh IM, Kashour T, Zimmerman V, Steckelberg JM, Wilson WR, Baddour LM (2008) The role of valve surgery in infective endocarditis management: a systematic review of observational studies that included propensity score analysis. Am Heart J 156:901-909
12. Herscu G, Wilson SE (2009) Prosthetic infection: lessons from treatment of the infected vascular graft. Surg Clin North Am 89:391-401
13. Rieger UM, Pierer G, Luscher NJ, Trampuz A (2009) Sonication of removed breast implants for improved detection of subclinical infection. Aesthet Plast Surg 33:404-408
14. Sanchez-Manuel FJ, Seco-Gil JL (2004) Antibiotic prophylaxis for hernia repair. Cochrane Database Syst Rev: CD003769
15. Gutierrez-Gonzalez R, Boto GR (2010) Do antibiotic-impregnated catheters prevent infection in CSF diversion procedures? Review of the literature. J Infect 61:9-20
16. Braxton EE Jr, Ehrlich GD, Hall-Stoodley L, Stoodley P, Veeh R, Fux C, Hu FZ, Quigley M, Post JC (2005) Role of biofilms in neurosurgical device-related infections. Neurosurg Rev 28:249-255 (Pubitemid 41317895)
17. Elek SD, Conen PE (1957) The virulence of Staphylococcus pyogenes for man; a study of the problems of wound infection. Br J Exp Pathol 38:573-586
18. Zimmerli W, Waldvogel FA, Vaudaux P, Nydegger UE (1982) Pathogenesis of foreign body infection: description and characteristics of an animal model. J Infect Dis 146:487-497 (Pubitemid 12004448)
19. Widmer AF, Frei R, Rajacic Z, Zimmerli W (1990) Correlation between in vivo and in vitro efficacy of antimicrobial agents against foreign body infections. J Infect Dis 162:96-102 (Pubitemid 20223955)
20. Zimmerli W, Zak O, Vosbeck K (1985) Experimental hematogenous infection of subcutaneously implanted foreign bodies. Scand J Infect Dis 17:303-310 (Pubitemid 15236708)
21. Murdoch DR, Roberts SA, Fowler VG Jr, Shah MA Jr, Taylor SL, Morris AJ, Corey GR (2001) Infection of orthopedic prostheses after Staphylococcus aureus bacteremia. Clin Infect Dis 32:647-649 (Pubitemid 32565009)
22. Lalani T, Chu VH, Grussemeyer CA, Reed SD, Bolognesi MP, Friedman JY, Griffiths RI, Crosslin DR, Kanafani ZA, Kaye KS, Ralph Corey G, Fowler VG Jr (2008) Clinical outcomes and costs among patients with Staphylococcus aureus bacteremia and orthopedic device infections. Scand J Infect Dis 40:973-977
23. Sendi P, Banderet F, Graber P, Zimmerli W (2011) Periprosthetic joint infection following Staphylococcus aureus bacteremia. J Infect (in press)
24. Zimmerli W, Lew PD, Waldvogel FA (1984) Pathogenesis of foreign body infection. Evidence for a local granulocyte defect. J Clin Invest 73:1191-1200 (Pubitemid 14132850)
25. Vaudaux P, Francois P, Lew D, Waldvogel FA (2000) Host factors predisposing to and influencing therapy of foreign body infections. In: Waldvogel FA, Bisno AL (eds) Infections Associated with Indwelling Medical Devices, 3rd edn. ASM, Washington
26. Forster TJ, Höök M (2000) Molecular basis of adherence of Staphylococcus aureus to Biomaterials. In: Waldvogel FA, Bisno AL (eds) Infections Associated with Indwelling Medical Devices, 3rd edn. ASM, Washington
27. Proctor RA (2000) Microbial pathogenic factors: small-colony variants. In: Waldvogel FA, Bisno AL (eds) Infections Associated with Indwelling Medical Devices, 3rd edn. ASM, Washington
28. Götz F, Peters G (2000) Colonization of medical devices by coagulase-negative Staphylococci. In: Waldvogel FA, Bisno AL (eds) Infections Associated with Indwelling Medical Devices, 3rd edn. ASM, Washington
29. Anderson JM, Marchant RE (2000) Biomaterials: Factors favoring colonization and infection. In: Waldvogel FA, Bisno AL (eds) Infections Associated with Indwelling Medical Devices, 3rd edn. ASM, Washington
30. Ha KY, Chung YG, Ryoo SJ (2005) Adherence and biofilm formation of Staphylococcus epidermidis and Mycobacterium tuberculosis on various spinal implants. Spine (Phila Pa 1976) 30: 38-43
31. Hudetz D, Ursic Hudetz S, Harris LG, Luginbuhl R, Friederich NF, Landmann R (2008) Weak effect of metal type and ica genes on staphylococcal infection of titanium and stainless steel implants. Clin Microbiol Infect 14:1135-1145
32. Zimmerli W, Trampuz A (2011) Implant-associated infection. In: Bjarnsholt T, Hoiby N, Moser C, Jensen PO (eds) Biofilms, 1st edn. Springer, Heidelberg
33. Lai BF, Creagh AL, Janzen J, Haynes CA, Brooks DE, Kizhakkedathu JN (2010) The induction of thrombus generation on nanostructured neutral polymer brush surfaces. Biomaterials 31:6710-6718
34. Coleman DL, King RN, Andrade JD (1974) The foreign body reaction: a chronic inflammatory response. J Biomed Mater Res 8:199-211
35. Takagi H, Goto SN, Matsui M, Manabe H, Umemoto T (2010) A contemporary meta-analysis of Dacron versus polytetrafluoroethylene grafts for femoropopliteal bypass grafting. J Vasc Surg 52:232-236
36. Kannan RY, Salacinski HJ, Butler PE, Hamilton G, Seifalian AM (2005) Current status of prosthetic bypass grafts: a review. J Biomed Mater Res B Appl Biomater 74:570-581 (Pubitemid 40917728)
37. Amarenco P, Labreuche J, Mazighi M (2010) Lessons from carotid endarterectomy and stenting trials. Lancet 376:1028-1031
38. Barnard J, Humphreys J, Bittar MN (2009) Endovascular versus open surgical repair for blunt thoracic aortic injury. Interact Cardiovasc Thorac Surg 9:506-509
39. Kidane AG, Burriesci G, Cornejo P, Dooley A, Sarkar S, Bonhoeffer P, Edirisinghe M, Seifalian AM (2009) Current developments and future prospects for heart valve replacement therapy. J Biomed Mater Res B Appl Biomater 88:290-303
40. Hammermeister K, Sethi GK, Henderson WG, Grover FL, Oprian C, Rahimtoola SH (2000) Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial. J Am Coll Cardiol 36:1152-1158
41. Oxenham H, Bloomfield P, Wheatley DJ, Lee RJ, Cunningham J, Prescott RJ, Miller HC (2003) Twenty year comparison of a Bjork-Shiley mechanical heart valve with porcine bioprostheses. Heart 89:715-721 (Pubitemid 36760624)
42. Kurtz SM, Ong KL, Lau E, Bozic KJ, Berry D, Parvizi J (2010) Prosthetic joint infection risk after TKA in the Medicare population. Clin Orthop Relat Res 468:52-56
43. Lethaby A, Temple J, Santy J (2008) Pin site care for preventing infections associated with external bone fixators and pins. Cochrane Database Syst Rev: CD004551
44. Harvey EJ, Henderson JE, Vengallatore ST (2010) Nanotechnology and bone healing. J Orthop Trauma 24(Suppl 1):S25-S30
45. Leekha S, Sampathkumar P, Berry DJ, Thompson RL (2010) Should national standards for reporting surgical site infections distinguish between primary and revision orthopedic surgeries? Infect Control Hosp Epidemiol 31:503-508
46. Achermann Y, Vogt M, Spormann C, Kolling C, Remschmidt C, Wust J, Simmen B, Trampuz A (2010) Characteristics and outcome of 27 elbow periprosthetic joint infection: Results from a 14-year cohort study of 358 elbow prostheses. [Epub ahead of print]. Clin Microbiol Infect
47. Finlay BB, Cossart P (1997) Exploitation of mammalian host cell functions by bacterial pathogens. Science 276:718-725 (Pubitemid 27199840)
48. Trampuz A, Zimmerli W (2008) Diagnosis and treatment of implant-associated septic arthritis and osteomyelitis. Curr Infect Dis Rep 10:394-403
49. Sendi P, Frei R, Maurer TB, Trampuz A, Zimmerli W, Graber P (2010) Escherichia coli variants in periprosthetic joint infection: diagnostic challenges with sessile bacteria and sonication. J Clin Microbiol 48:1720-1725
50. Verhoef J (1991) The phagocytic process and the role of complement in host defense. J Chemother 3(Suppl 1):93-97
51. Zimmerli W, Zarth A, Gratwohl A, Speck B (1991) Neutrophil function and pyogenic infections in bone marrow transplant recipients. Blood 77:393-399
52. Herrmann M, Vaudaux PE, Pittet D, Auckenthaler R, Lew PD, Schumacher-Perdreau F, Peters G, Waldvogel FA (1988) Fibronectin, fibrinogen, and laminin act as mediators of adherence of clinical staphylococcal isolates to foreign material. J Infect Dis 158:693-701
53. Vaudaux P, Pittet D, Haeberli A, Lerch PG, Morgenthaler JJ, Proctor RA, Waldvogel FA, Lew DP (1993) Fibronectin is more active than fibrin or fibrinogen in promoting Staphylococcus aureus adherence to inserted intravascular catheters. J Infect Dis 167:633-641 (Pubitemid 23056330)
54. Lopes JD, dos Reis M, Brentani RR (1985) Presence of laminin receptors in Staphylococcus aureus. Science 229:275-277 (Pubitemid 15229301)
55. Zimmerli W (1999) Tissue cage infection model; Chapter 47 In: Handbook of animal models of infection ISBN 0-12-775390- 7:409-417
56. Kristian SA, Golda T, Ferracin F, Cramton SE, Neumeister B, Peschel A, Gotz F, Landmann R (2004) The ability of biofilm formation does not influence virulence of Staphylococcus aureus and host response in a mouse tissue cage infection model. Microb Pathog 36:237-245 (Pubitemid 38388254)
57. Kristian SA, Birkenstock TA, Sauder U, Mack D, Gotz F, Landmann R (2008) Biofilm formation induces C3a release and protects Staphylococcus epidermidis from IgG and complement deposition and from neutrophil-dependent killing. J Infect Dis 197:1028-1035 (Pubitemid 351590032)
58. Bernard L, Vaudaux P, Merle C, Stern R, Huggler E, Lew D, Hoffmeyer P (2005) The inhibition of neutrophil antibacterial activity by ultra-high molecular weight polyethylene particles. Biomaterials 26:5552-5557 (Pubitemid 40592142)
59. Klock JC, Stossel TP (1977) Detection, pathogenesis, and prevention of damage to human granulocytes caused by interaction with nylon wool fiber. Implications for filtration leukapheresis. J Clin Invest 60:1183-1190 (Pubitemid 8223146)
60. Wright DG, Gallin JI (1979) Secretory responses of human neutrophils: exocytosis of specific (secondary) granules by human neutrophils during adherence in vitro and during exudation in vivo. J Immunol 123:285-294 (Pubitemid 9218676)
61. Kaplan SS, Heine RP, Simmons RL (1999) Defensins impair phagocytic killing by neutrophils in biomaterial-related infection. Infect Immun 67:1640-1645 (Pubitemid 29144376)
62. Chang S, Popowich Y, Greco RS, Haimovich B (2003) Neutrophil survival on biomaterials is determined by surface topography. J Vasc Surg 37:1082-1090 (Pubitemid 36538935)
63. Leid JG, Shirtliff ME, Costerton JW, Stoodley P (2002) Human leukocytes adhere to, penetrate, and respond to Staphylococcus aureus biofilms. Infect Immun 70:6339-6345 (Pubitemid 35192726)
64. Olofsson P, Rabahie GN, Matsumoto K, Ehrenfeld WK, Ferrell LD, Goldstone J, Reilly LM, Stoney RJ (1995) Histopathological characteristics of explanted human prosthetic arterial grafts: implications for the prevention and management of graft infection. Eur J Vasc Endovasc Surg 9:143-151
65. Bohler J, Kramer P, Gotze O, Schwartz P, Scheler F (1983) Leucocyte counts and complement activation during pumpdriven and arteriovenous haemofiltration. Contrib Nephrol 36:15-25
66. Burhop KE, Johnson RJ, Simpson J, Chenoweth DE, Borgia J (1993) Biocompatibility of hemodialysis membranes: evaluation in an ovine model. J Lab Clin Med 121:276-293 (Pubitemid 23073135)
67. Hammerschmidt DE, Craddock PR, McCullough F, Kronenberg RS, Dalmasso AP, Jacob HS (1978) Complement activation and pulmonary leukotasis during nylon fiber filtration leukapheresis. Blood 51:721-730 (Pubitemid 8313155)
68. Moczar M, Lecerf L, Ginat M, Loisance D (1996) Complement activation is involved in the structural deterioration of bovine pericardial bioprosthetic heart valves. ASAIO J 42:M375-M381 (Pubitemid 26363693)
69. Shepard AD, Gelfand JA, Callow AD, O'Donnell TF Jr (1984) Complement activation by synthetic vascular prostheses. J Vasc Surg 1:829-838 (Pubitemid 15056080)
70. Anderson JM (1988) Inflammatory response to implants. ASAIO Trans 34:101-107
71. Tang L, Liu L, Elwing HB (1998) Complement activation and inflammation triggered by model biomaterial surfaces. J Biomed Mater Res 41:333-340 (Pubitemid 28272492)
72. Bauer TW, Schils J (1999) The pathology of total joint arthroplasty. II. Mechanisms of implant failure. Skeletal Radiol 28:483-497 (Pubitemid 29467039)
73. DeHeer DH, Engels JA, DeVries AS, Knapp RH, Beebe JD (2001) In situ complement activation by polyethylene wear debris. J Biomed Mater Res 54:12-19
74. Hugli TE, Muller-Eberhard HJ (1978) Anaphylatoxins: C3a and C5a. Adv Immunol 26:1-53
75. Nelson CL, McLaren AC, McLaren SG, Johnson JW, Smeltzer MS (2005) Is aseptic loosening truly aseptic? Clin Orthop Relat Res: 25-30 (Pubitemid 41099062)
76. Moojen DJ, van Hellemondt G, Vogely HC, Burger BJ, Walenkamp GH, Tulp NJ, Schreurs BW, de Meulemeester FR, Schot CS, van de Pol I, Fujishiro T, Schouls LM, Bauer TW, Dhert WJ (2010) Incidence of low-grade infection in aseptic loosening of total hip arthroplasty. [Epub ahead of print] Acta Orthop
77. Teronen O, Konttinen YT, Lindqvist C, Salo T, Ingman T, Lauhio A, Ding Y, Santavirta S, Sorsa T (1997) Human neutrophil collagenase MMP-8 in peri-implant sulcus fluid and its inhibition by clodronate. J Dent Res 76:1529-1537 (Pubitemid 127748945)
78. Velard F, Laurent-Maquin D, Guillaume C, Bouthors S, Jallot E, Nedelec JM, Belaaouaj A, Laquerriere P (2009) Polymorphonuclear neutrophil response to hydroxyapatite particles, implication in acute inflammatory reaction. Acta Biomater 5:1708-1715
79. Bernard L, Vaudaux P, Huggler E, Stern R, Frehel C, Francois P, Lew D, Hoffmeyer P (2007) Inactivation of a subpopulation of human neutrophils by exposure to ultrahigh-molecular-weight polyethylene wear debris. FEMS Immunol Med Microbiol 49:425-432 (Pubitemid 46435022)
80. Tuan RS, Lee FY, Konttinen YT, Wilkinson JM, Smith RL (2008) What are the local and systemic biologic reactions and mediators to wear debris, and what host factors determine or modulate the biologic response to wear particles? J Am Acad Orthop Surg 16(1):S42-S48
81. Revell PA (2008) The combined role of wear particles, macrophages and lymphocytes in the loosening of total joint prostheses. J R Soc Interface 5:1263-1278
82. Malone JM, Moore WS, Campagna G, Bean B (1975) Bacteremic infectability of vascular grafts: the influence of pseudointimal integrity and duration of graft function. Surgery 78:211-216
83. Moore WS, Malone JM, Keown K (1980) Prosthetic arterial graft material. Influence on neointimal healing and bacteremic infectibility. Arch Surg 115:1379-1383 (Pubitemid 10024660)
84. Foth R, Quentin T, Michel-Behnke I, Vogt M, Kriebel T, Kreischer A, Ruschewski W, Paul T, Sigler M (2009) Immunohistochemical characterization of neotissues and tissue reactions to septal defectocclusion devices. Circ Cardiovasc Interv 2:90-96
85. Costerton JW, Geesey GG, Cheng KJ (1978) How bacteria stick. Sci Am 238:86-95
86. Donlan RM (2001) Biofilms and device-associated infections. Emerg Infect Dis 7:277-281 (Pubitemid 32374344)
87. Donlan RM (2002) Biofilms: microbial life on surfaces. Emerg Infect Dis 8:881-890 (Pubitemid 35000803)
88. Hall-Stoodley L, Costerton JW, Stoodley P (2004) Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2:95-108 (Pubitemid 39490064)
89. Baldoni D, Haschke M, Rajacic Z, Zimmerli W, Trampuz A (2009) Linezolid alone or combined with rifampin against methicillin-resistant Staphylococcus aureus in experimental foreign-body infection. Antimicrob Agents Chemother 53:1142-1148
90. John AK, Baldoni D, Haschke M, Rentsch K, Schaerli P, Zimmerli W, Trampuz A (2009) Efficacy of daptomycin in implant-associated infection due to methicillin-resistant Staphylococcus aureus: importance of combination with rifampin. Antimicrob Agents Chemother 53:2719-2724
91. Widmer AF, Wiestner A, Frei R, Zimmerli W (1991) Killing of nongrowing and adherent Escherichia coli determines drug efficacy in device-related infections. AntimicrobAgents Chemother 35:741-746
92. Zimmerli W, Frei R, Widmer AF, Rajacic Z (1994) Microbiological tests to predict treatment outcome in experimental devicerelated infections due to Staphylococcus aureus. J Antimicrob Chemother 33:959-967 (Pubitemid 24170895)
93. Vaudaux PE, Zulian G, Huggler E, Waldvogel FA (1985) Attachment of Staphylococcus aureus to polymethylmethacrylate increases its resistance to phagocytosis in foreign body infection. Infect Immun 50:472-477 (Pubitemid 16246266)
94. von Eiff C, Peters G, Heilmann C (2002) Pathogenesis of infections due to coagulase-negative staphylococci. Lancet Infect Dis 2:677-685 (Pubitemid 35265063)
95. Proctor RA, von Eiff C, Kahl BC, Becker K, McNamara P, Herrmann M, Peters G (2006) Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections. Nat Rev Microbiol 4:295-305
96. Million M, Thuny F, Richet H, Raoult D (2010) Long-term outcome of Q fever endocarditis: a 26-year personal survey. Lancet Infect Dis 10:527-535
97. Fournier PE, Casalta JP, Piquet P, Tournigand P, Branchereau A, Raoult D (1998) Coxiella burnetii infection of aneurysms or vascular grafts: report of seven cases and review. Clin Infect Dis 26:116-121 (Pubitemid 28068164)
98. Senn L, Franciolli M, Raoult D, Moulin A, Von Segesser L, Calandra T, Greub G (2005) Coxiella burnetii vascular graft infection. BMC Infect Dis 5:109
99. Raoult D, Marrie T, Mege J (2005) Natural history and pathophysiology of Q fever. Lancet Infect Dis 5:219-226 (Pubitemid 40410067)
100. Capo C, Moynault A, Collette Y, Olive D, Brown EJ, Raoult D, Mege JL (2003) Coxiella burnetii avoids macrophage phagocytosis by interfering with spatial distribution of complement receptor 3. J Immunol 170:4217-4225 (Pubitemid 36428188)
101. Capo C, Lindberg FP, Meconi S, Zaffran Y, Tardei G, Brown EJ, Raoult D, Mege JL (1999) Subversion of monocyte functions by coxiella burnetii: impairment of the cross-talk between alphavbeta3 integrin and CR3. J Immunol 163:6078-6085
102. Ghigo E, Capo C, Tung CH, Raoult D, Gorvel JP, Mege JL (2002) Coxiella burnetii survival in THP-1 monocytes involves the impairment of phagosome maturation: IFN-gamma mediates its restoration and bacterial killing. J Immunol 169:4488-4495 (Pubitemid 35178226)
103. Higgins DM, Basaraba RJ, Hohnbaum AC, Lee EJ, Grainger DW, Gonzalez-Juarrero M (2009) Localized immunosuppressive environment in the foreign body response to implanted biomaterials. Am J Pathol 175:161-170
104. Mege JL, Meghari S, Honstettre A, Capo C, Raoult D (2006) The two faces of interleukin 10 in human infectious diseases. Lancet Infect Dis 6:557-569 (Pubitemid 44262343)
105. Widmer AF, Colombo VE, Gachter A, Thiel G, Zimmerli W (1990) Salmonella infection in total hip replacement: tests to predict the outcome of antimicrobial therapy. Scand J Infect Dis 22:611-618 (Pubitemid 20354261)
106. Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Osmon DR (1998) Prosthetic joint infection due to Mycobacterium tuberculosis: a case series and review of the literature. Am J Orthop Belle Mead NJ 27:219-227
107. Eid AJ, Berbari EF, Sia IG, Wengenack NL, Osmon DR, Razonable RR (2007) Prosthetic joint infection due to rapidly growing mycobacteria: report of 8 cases and review of the literature. Clin Infect Dis 45:687-694 (Pubitemid 47378881)
108. Ellis LC, Segreti J, Gitelis S, Huber JF (1995) Joint infections due to Listeria monocytogenes: case report and review. Clin Infect Dis 20:1548-1550
109. Van Noyen R, Reybrouck R, Peeters P, Verheyen L, Vandepitte J (1993) Listeria monocytogenes infection of a prosthetic vascular graft. Infection 21:125-126 (Pubitemid 23112603)
110. Ward AS, Russell AJ (1991) Salmonella vascular graft infection. Lancet 337:735
111. Wright RA, Yang F, Moore WS (1977) Tuberculous infection in a vascular prosthesis: a case of aortic graft infection resulting from disseminated tuberculosis. Arch Surg 112:79-81
112. Clerc O, Jaton K, Prod'hom G, Von Segesser L, Greloz V, Greub G (2008) Mycobacterium tuberculosis aortic graft infection with recurrent hemoptysis: a case report. J Med Case Rep 2:233
113. Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O (2003) DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J Exp Med 197:121-127 (Pubitemid 36110263)
114. Chen WH, Jiang LS, Dai LY Influence of Bacteria on Spinal Implant-Centered Infection: An in vitro and in vivo experimental comparison between Staphylococcus aureus and Mycobacterium tuberculosis. Spine (Phila Pa 1976)
115. Ray K, Marteyn B, Sansonetti PJ, Tang CM (2009) Life on the inside: the intracellular lifestyle of cytosolic bacteria. Nat Rev Microbiol 7:333-340
116. Borucki MK, Peppin JD, White D, Loge F, Call DR (2003) Variation in biofilm formation among strains of Listeria monocytogenes. Appl Environ Microbiol 69:7336-7342 (Pubitemid 38585386)
117. Prouty AM, Schwesinger WH, Gunn JS (2002) Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp. Infect Immun 70:2640-2649 (Pubitemid 34408410)
118. Sendi P, Proctor RA (2009) Staphylococcus aureus as an intracellular pathogen: the role of small colony variants. Trends Microbiol 17:54-58
119. Spanu T, Romano L, D'Inzeo T, Masucci L, Albanese A, Papacci F, Marchese E, Sanguinetti M, Fadda G (2005) Recurrent ventriculoperitoneal shunt infection caused by small-colony variants of Staphylococcus aureus. Clin Infect Dis 41:e48-e52
120. Sendi P, Rohrbach M, Graber P, Frei R, Ochsner PE, Zimmerli W (2006) Staphylococcus aureus small colony variants in prosthetic joint infection. Clin Infect Dis 43:961-967 (Pubitemid 44631093)
121. von Eiff C, Becker K, Metze D, Lubritz G, Hockmann J, Schwarz T, Peters G (2001) Intracellular persistence of Staphylococcus aureus small-colony variants within keratinocytes: a cause for antibiotic treatment failure in a patient with Darier's disease. Clin Infect Dis 32:1643-1647 (Pubitemid 32458736)
122. Proctor RA, van Langevelde P, Kristjansson M, Maslow JN, Arbeit RD (1995) Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus. Clin Infect Dis 20:95-102
123. Williams DF (2008) On the mechanisms of biocompatibility. Biomaterials 29:2941-2953
124. Smith LJ, Swaim JS, Yao C, Haberstroh KM, Nauman EA, Webster TJ (2007) Increased osteoblast cell density on nanostructured PLGA-coated nanostructured titanium for orthopedic applications. Int J Nanomedicine 2:493-499 (Pubitemid 350047792)
125. Montanaro L, Campoccia D, Arciola CR (2008) Nanostructured materials for inhibition of bacterial adhesion in orthopedic implants: a minireview. Int J Artif Organs 31:771-776
126. Ferraz N, Nilsson B, Hong J, Karlsson Ott M (2008) Nanoporesize affects complement activation. J Biomed Mater Res A 87:575-581
127. Groll J, Fiedler J, Bruellhoff K, Moeller M, Brenner RE (2009) Novel surface coatings modulating eukaryotic cell adhesion and preventing implant infection. Int J Artif Organs 32:655-662
128. Ochsner PE (2011) Osteointegration of orthopaedic devices. Semin Immunopathol (this issue)
129. Raimondo T, Puckett S, Webster TJ (2010) Greater osteoblast and endothelial cell adhesion on nanostructured polyethylene and titanium. Int J Nanomedicine 5:647-652
130. Yim EK, Leong KW (2005) Significance of synthetic nanostructures in dictating cellular response. Nanomedicine 1:10-21 (Pubitemid 43963610)
131. Webster TJ, Siegel RW, Bizios R (1999) Osteoblast adhesion on nanophase ceramics. Biomaterials 20:1221-1227 (Pubitemid 29279815)
132. Shi Z, Neoh KG, Kang ET, Wang W (2006) Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles. Biomaterials 27:2440-2449 (Pubitemid 41821823)
133. Dalby MJ, Marshall GE, Johnstone HJ, Affrossman S, Riehle MO (2002) Interactions of human blood and tissue cell types with 95-nm-high nanotopography. IEEE Trans Nanobioscience 1:18-23 (Pubitemid 44357759)
134. Dalby MJ, Riehle MO, Johnstone H, Affrossman S, Curtis AS (2002) In vitro reaction of endothelial cells to polymer demixed nanotopography. Biomaterials 23:2945-2954 (Pubitemid 34497086)
135. Villa A, Arnold R, Sanchez PL, Gimeno F, Ramos B, Cantero T, Fernandez ME, Sanz R, Gutierrez O, Mota P, Garcia-Frade J, San Roman JA, Fernandez-Aviles F (2009) Comparison of neointimal hyperplasia with drug-eluting stents versus bare metal stents in patients undergoing intracoronary bone-marrow mononuclear cell transplantation following acute myocardial infarction. Am J Cardiol 103:1651-1656
136. Jensen LO, Maeng M, Kaltoft A, Thayssen P, Hansen HH, Bottcher M, Lassen JF, Krussel LR, Rasmussen K, Hansen KN, Pedersen L, Johnsen SP, Soerensen HT, Thuesen L (2007) Stent thrombosis, myocardial infarction, and death after drug-eluting and bare-metal stent coronary interventions. J Am Coll Cardiol 50:463-470 (Pubitemid 47088133)
137. Stettler C, Wandel S, Allemann S, Kastrati A, Morice MC, Schomig A, Pfisterer ME, Stone GW, Leon MB, de Lezo JS, Goy JJ, Park SJ, Sabate M, Suttorp MJ, Kelbaek H, Spaulding C, Menichelli M, Vermeersch P, Dirksen MT, Cervinka P, Petronio AS, Nordmann AJ, Diem P, Meier B, Zwahlen M, Reichenbach S, Trelle S, Windecker S, Juni P (2007) Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis. Lancet 370:937-948 (Pubitemid 47393576)
138. Morice MC, Serruys PW, Sousa JE, Fajadet J, Ban Hayashi E, Perin M, Colombo A, Schuler G, Barragan P, Guagliumi G, Molnar F, Falotico R (2002) A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med 346:1773-1780 (Pubitemid 34586912)
139. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE (2003) Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 349:1315-1323 (Pubitemid 37186209)
140. Stone GW, Ellis SG, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, Turco M, Caputo R, Bergin P, Greenberg J, Popma JJ, Russell ME (2004) A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med 350:221-231 (Pubitemid 38067635)
141. Stone GW, Ellis SG, Cannon L, Mann JT, Greenberg JD, Spriggs D, O'Shaughnessy CD, DeMaio S, Hall P, Popma JJ, Koglin J, Russell ME (2005) Comparison of a polymer-based paclitaxeleluting stent with a bare metal stent in patients with complex coronary artery disease: a randomized controlled trial. JAMA 294:1215-1223 (Pubitemid 41352109)
142. Antonios VS, Baddour LM (2004) Intra-arterial device infections. Curr Infect Dis Rep 6:263-269 (Pubitemid 39173559)
143. Chambers CE (2009) Intracoronary stent infection. Beware the bugs. Catheter Cardiovasc Interv 73:77
144. Schoenkerman AB, Lundstrom RJ (2009) Coronary stent infections: a case series. Catheter Cardiovasc Interv 73:74-76
145. Groll J, Fiedler J, Engelhard E, Ameringer T, Tugulu S, Klok HA, Brenner RE, Moeller M (2005) A novel star PEG-derived surface coating for specific cell adhesion. J Biomed Mater Res A 74:607-617 (Pubitemid 41216263)
146. Gottenbos B, Grijpma DW, van der Mei HC, Feijen J, Busscher HJ (2001) Antimicrobial effects of positively charged surfaces on adhering Gram-positive and Gram-negative bacteria. J Antimicrob Chemother 48:7-13 (Pubitemid 32684719)
147. Li B, Jiang B, Boyce BM, Lindsey BA (2009) Multilayer polypeptide nanoscale coatings incorporating IL-12 for the prevention of biomedical device-associated infections. Biomaterials 30:2552-2558
148. Ehrlich GD, Hu FZ, Costerton QLJW, Post JC (2004) Intelligent implants to battle biofilms. ASM News 70:127-133 (Pubitemid 41296256)
149. Coelho LR, Souza RR, Ferreira FA, Guimaraes MA, Ferreira-Carvalho BT, Figueiredo AM (2008) agr RNAIII divergently regulates glucose-induced biofilm formation in clinical isolates of Staphylococcus aureus. Microbiology 154:3480-3490