메뉴 건너뛰기




Volumn 44, Issue 4, 2011, Pages 637-647

Systems-based biological concordance and predictive reproducibility of gene set discovery methods in cardiovascular disease

Author keywords

Biomarker discovery; Cardiovascular diseases; Disease networks; Gene set analysis; Human heart failure; Pathway analysis; Translational bioinformatics

Indexed keywords

BIO-MARKER DISCOVERY; CARDIO-VASCULAR DISEASE; HUMAN HEART; PATHWAY ANALYSIS; TRANSLATIONAL BIOINFORMATICS;

EID: 79960559668     PISSN: 15320464     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbi.2011.02.003     Document Type: Article
Times cited : (8)

References (61)
  • 1
    • 67449095891 scopus 로고    scopus 로고
    • Computational biology for cardiovascular biomarker discovery
    • Azuaje F., Devaux Y., Wagner D. Computational biology for cardiovascular biomarker discovery. Brief Bioinform 2009, 10:367-377.
    • (2009) Brief Bioinform , vol.10 , pp. 367-377
    • Azuaje, F.1    Devaux, Y.2    Wagner, D.3
  • 2
    • 70849108991 scopus 로고    scopus 로고
    • Drivers of biodiagnostic development
    • Giljohann D.A., Mirkin C.A. Drivers of biodiagnostic development. Nature 2009, 462:461-464.
    • (2009) Nature , vol.462 , pp. 461-464
    • Giljohann, D.A.1    Mirkin, C.A.2
  • 3
    • 77952744198 scopus 로고    scopus 로고
    • Current methodologies for translational bioinformatics
    • Lussier Y.A., Butte A.J., Hunter L. Current methodologies for translational bioinformatics. J Biomed Inform 2010, 43:355-357.
    • (2010) J Biomed Inform , vol.43 , pp. 355-357
    • Lussier, Y.A.1    Butte, A.J.2    Hunter, L.3
  • 4
    • 77949900831 scopus 로고    scopus 로고
    • Translational bioinformatics applications in genome medicine
    • Butte A.J. Translational bioinformatics applications in genome medicine. Genome Med 2009, 1:64.
    • (2009) Genome Med , vol.1 , pp. 64
    • Butte, A.J.1
  • 5
    • 35748932917 scopus 로고    scopus 로고
    • A review of feature selection techniques in bioinformatics
    • Saeys Y., Inza I., Larrañaga P. A review of feature selection techniques in bioinformatics. Bioinformatics 2007, 23:2507-2517.
    • (2007) Bioinformatics , vol.23 , pp. 2507-2517
    • Saeys, Y.1    Inza, I.2    Larrañaga, P.3
  • 6
    • 70350465146 scopus 로고    scopus 로고
    • Large datasets in biomedicine: a discussion of salient analytic issues
    • Sinha A., Hripcsak G., Markatou M. Large datasets in biomedicine: a discussion of salient analytic issues. J Am Med Inform Assoc 2009, 16:759-767.
    • (2009) J Am Med Inform Assoc , vol.16 , pp. 759-767
    • Sinha, A.1    Hripcsak, G.2    Markatou, M.3
  • 7
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey J.D., Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003, 100:9440-9445.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 8
    • 0037433040 scopus 로고    scopus 로고
    • Identifying differentially expressed genes using false discovery rate controlling procedures
    • Reiner A., Yekutieli D., Benjamini Y. Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics 2003, 19:368-375.
    • (2003) Bioinformatics , vol.19 , pp. 368-375
    • Reiner, A.1    Yekutieli, D.2    Benjamini, Y.3
  • 9
    • 85137158608 scopus 로고    scopus 로고
    • Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions. PLoS Comput Biol :pii:e1000940.
    • Chen R, Sigdel TK, Li L, Kambham N, Dudley JT, Hsieh SC, et al. Differentially expressed RNA from public microarray data identifies serum protein biomarkers for cross-organ transplant rejection and other conditions. PLoS Comput Biol 2010;6:pii:e1000940.
    • (2010) , vol.6
    • Chen, R.1    Sigdel, T.K.2    Li, L.3    Kambham, N.4    Dudley, J.T.5    Hsieh, S.C.6
  • 10
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • Schadt E.E. Molecular networks as sensors and drivers of common human diseases. Nature 2009, 461:218-223.
    • (2009) Nature , vol.461 , pp. 218-223
    • Schadt, E.E.1
  • 11
    • 70350682038 scopus 로고    scopus 로고
    • Statistical methods for gene set co-expression analysis
    • Choi Y., Kendziorski C. Statistical methods for gene set co-expression analysis. Bioinformatics 2009, 25:2780-2786.
    • (2009) Bioinformatics , vol.25 , pp. 2780-2786
    • Choi, Y.1    Kendziorski, C.2
  • 12
  • 13
    • 77949365759 scopus 로고    scopus 로고
    • Identification of functional modules that correlate with phenotypic difference: the influence of network topology
    • Hung J.H., Whitfield T.W., Yang T.H., Hu Z., Weng Z., DeLisi C. Identification of functional modules that correlate with phenotypic difference: the influence of network topology. Genome Biol 2010, 11:R23.
    • (2010) Genome Biol , vol.11
    • Hung, J.H.1    Whitfield, T.W.2    Yang, T.H.3    Hu, Z.4    Weng, Z.5    DeLisi, C.6
  • 15
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A., Tamayo P., Mootha V.K., Mukherjee S., Ebert B.L., Gillette M.A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005, 102:15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 16
    • 77950540760 scopus 로고    scopus 로고
    • Integrative pathway-centric modeling of ventricular dysfunction after myocardial infarction
    • Azuaje F., Devaux Y., Wagner D.R. Integrative pathway-centric modeling of ventricular dysfunction after myocardial infarction. PLoS ONE 2010, 5:e966.
    • (2010) PLoS ONE , vol.5
    • Azuaje, F.1    Devaux, Y.2    Wagner, D.R.3
  • 17
    • 39149143293 scopus 로고    scopus 로고
    • A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
    • Mani K.M., Lefebvre C., Wang K., Lim W.K., Basso K., Dalla-Favera R., et al. A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas. Mol Syst Biol 2008, 4:169.
    • (2008) Mol Syst Biol , vol.4 , pp. 169
    • Mani, K.M.1    Lefebvre, C.2    Wang, K.3    Lim, W.K.4    Basso, K.5    Dalla-Favera, R.6
  • 18
    • 77953255983 scopus 로고    scopus 로고
    • A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers
    • Lefebvre C., Rajbhandari P., Alvarez M.J., Bandaru P., Lim W.K., Sato M., et al. A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers. Mol Syst Biol 2010, 6:377.
    • (2010) Mol Syst Biol , vol.6 , pp. 377
    • Lefebvre, C.1    Rajbhandari, P.2    Alvarez, M.J.3    Bandaru, P.4    Lim, W.K.5    Sato, M.6
  • 19
    • 75149195336 scopus 로고    scopus 로고
    • The transcriptional network for mesenchymal transformation of brain tumours
    • Carro M.S., Lim W.K., Alvarez M.J., Bollo R.J., Zhao X., Snyder E.Y., et al. The transcriptional network for mesenchymal transformation of brain tumours. Nature 2010, 463:318-325.
    • (2010) Nature , vol.463 , pp. 318-325
    • Carro, M.S.1    Lim, W.K.2    Alvarez, M.J.3    Bollo, R.J.4    Zhao, X.5    Snyder, E.Y.6
  • 20
    • 77953391592 scopus 로고    scopus 로고
    • What does systems biology mean for biomarker discovery?
    • Azuaje F. What does systems biology mean for biomarker discovery?. Expert Opin Med Diagn 2010, 4:1-10.
    • (2010) Expert Opin Med Diagn , vol.4 , pp. 1-10
    • Azuaje, F.1
  • 22
    • 62549162170 scopus 로고    scopus 로고
    • Genomics and cardiovascular drug development
    • Plump A.S., Lum P.Y. Genomics and cardiovascular drug development. J Am Coll Cardiol 2009, 53:1089-1100.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1089-1100
    • Plump, A.S.1    Lum, P.Y.2
  • 23
    • 77953004083 scopus 로고    scopus 로고
    • Why most gene expression signatures of tumors have not been useful in the clinic
    • Koscielny S. Why most gene expression signatures of tumors have not been useful in the clinic. Sci Transl Med 2010, 2:14ps2.
    • (2010) Sci Transl Med , vol.2
    • Koscielny, S.1
  • 24
    • 41649109807 scopus 로고    scopus 로고
    • Translating insights from the cancer genome into clinical practice
    • Chin L., Gray J.W. Translating insights from the cancer genome into clinical practice. Nature 2008, 452:553-563.
    • (2008) Nature , vol.452 , pp. 553-563
    • Chin, L.1    Gray, J.W.2
  • 25
    • 39749145196 scopus 로고    scopus 로고
    • Translating molecular discoveries into new therapies for atherosclerosis
    • Rader D.J., Daugherty A. Translating molecular discoveries into new therapies for atherosclerosis. Nature 2008, 451:904-913.
    • (2008) Nature , vol.451 , pp. 904-913
    • Rader, D.J.1    Daugherty, A.2
  • 27
    • 77955493761 scopus 로고    scopus 로고
    • Analysis and computational dissection of molecular signature multiplicity
    • Statnikov A., Aliferis C.F. Analysis and computational dissection of molecular signature multiplicity. PLoS Comput Biol 2010, 6:e1000790.
    • (2010) PLoS Comput Biol , vol.6
    • Statnikov, A.1    Aliferis, C.F.2
  • 29
    • 25444485444 scopus 로고    scopus 로고
    • The effects of normalization on the correlation structure of microarray data
    • Qiu X., Brooks A.I., Klebanov L., Yakovlev N. The effects of normalization on the correlation structure of microarray data. BMC Bioinform 2005, 6:120.
    • (2005) BMC Bioinform , vol.6 , pp. 120
    • Qiu, X.1    Brooks, A.I.2    Klebanov, L.3    Yakovlev, N.4
  • 30
    • 33645825183 scopus 로고    scopus 로고
    • Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer
    • Ein-Dor L., Zuk O., Domany E. Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer. Proc Natl Acad Sci USA 2006, 103:5923-5928.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5923-5928
    • Ein-Dor, L.1    Zuk, O.2    Domany, E.3
  • 31
    • 33644507403 scopus 로고    scopus 로고
    • Multiple robust signatures for detecting lymph node metastasis in head and neck cancer
    • Roepman P., Kemmeren P., Wessels L.F., Slootweg P.J., Holstege F.C. Multiple robust signatures for detecting lymph node metastasis in head and neck cancer. Cancer Res 2006, 66:2361-2366.
    • (2006) Cancer Res , vol.66 , pp. 2361-2366
    • Roepman, P.1    Kemmeren, P.2    Wessels, L.F.3    Slootweg, P.J.4    Holstege, F.C.5
  • 32
    • 78650735473 scopus 로고    scopus 로고
    • The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
    • Consortium MAQC The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol 2010, 28:827-838.
    • (2010) Nat Biotechnol , vol.28 , pp. 827-838
    • Consortium, M.A.Q.C.1
  • 33
    • 46349084468 scopus 로고    scopus 로고
    • Multiple oncogeneic pathway signatures shows coordinate expression patterns in human prostate tumors
    • Creighton C.J. Multiple oncogeneic pathway signatures shows coordinate expression patterns in human prostate tumors. PLoS ONE 2008, 3:e1816.
    • (2008) PLoS ONE , vol.3
    • Creighton, C.J.1
  • 34
    • 77952743808 scopus 로고    scopus 로고
    • On the reproducibility of results of pathway analysis in genome-wide expression studies of colorectal cancers
    • Maglietta R., Distaso A., Piepoli A., Palumbo O., Carella M., D'Addabbo A., et al. On the reproducibility of results of pathway analysis in genome-wide expression studies of colorectal cancers. J Biomed Inform 2010, 43:397-406.
    • (2010) J Biomed Inform , vol.43 , pp. 397-406
    • Maglietta, R.1    Distaso, A.2    Piepoli, A.3    Palumbo, O.4    Carella, M.5    D'Addabbo, A.6
  • 35
    • 77952745604 scopus 로고    scopus 로고
    • Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures
    • Chen J., Sam L., Huang Y., Lee Y., Li J., Liu Y., et al. Protein interaction network underpins concordant prognosis among heterogeneous breast cancer signatures. J Biomed Inform 2010, 43:385-396.
    • (2010) J Biomed Inform , vol.43 , pp. 385-396
    • Chen, J.1    Sam, L.2    Huang, Y.3    Lee, Y.4    Li, J.5    Liu, Y.6
  • 36
    • 33749999763 scopus 로고    scopus 로고
    • Group testing for pathway analysis improves comparability of different microarray datasets
    • Manoli T., Gretz N., Gröne H.J., Kenzelmann M., Eils R., Brors B. Group testing for pathway analysis improves comparability of different microarray datasets. Bioinformatics 2006, 22:2500-2506.
    • (2006) Bioinformatics , vol.22 , pp. 2500-2506
    • Manoli, T.1    Gretz, N.2    Gröne, H.J.3    Kenzelmann, M.4    Eils, R.5    Brors, B.6
  • 37
    • 33749515603 scopus 로고    scopus 로고
    • Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies
    • Barth A.S., Kuner R., Buness A., Ruschhaupt M., Merk S., Zwermann L., et al. Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies. J Am Coll Cardiol 2006, 48:1610-1617.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1610-1617
    • Barth, A.S.1    Kuner, R.2    Buness, A.3    Ruschhaupt, M.4    Merk, S.5    Zwermann, L.6
  • 38
    • 21344442672 scopus 로고    scopus 로고
    • Gene expression analysis of ischemic and nonischemic cardiomyopathy, shared and distinct genes in the development of heart failure
    • Kittleson M.M., Minhas K.M., Irizarry R.A., Ye S.Q., Edness G., Breton E., et al. Gene expression analysis of ischemic and nonischemic cardiomyopathy, shared and distinct genes in the development of heart failure. Physiol Genomics 2005, 21:299-307.
    • (2005) Physiol Genomics , vol.21 , pp. 299-307
    • Kittleson, M.M.1    Minhas, K.M.2    Irizarry, R.A.3    Ye, S.Q.4    Edness, G.5    Breton, E.6
  • 39
    • 33748745399 scopus 로고    scopus 로고
    • Transcriptional genomics associates FOX transcription factors with human heart failure
    • Hannenhalli S., Putt M.E., Gilmore J.M., Wang J., Parmacek M.S., Epstein J.A., et al. Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation 2006, 114:1269-1276.
    • (2006) Circulation , vol.114 , pp. 1269-1276
    • Hannenhalli, S.1    Putt, M.E.2    Gilmore, J.M.3    Wang, J.4    Parmacek, M.S.5    Epstein, J.A.6
  • 40
    • 77957812882 scopus 로고    scopus 로고
    • Ontology- and graph-based similarity assessment in biological networks
    • Wang H., Zheng H., Azuaje F. Ontology- and graph-based similarity assessment in biological networks. Bioinformatics 2010, 26:2643-2644.
    • (2010) Bioinformatics , vol.26 , pp. 2643-2644
    • Wang, H.1    Zheng, H.2    Azuaje, F.3
  • 41
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth G.K. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004, 3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 42
    • 34547743829 scopus 로고    scopus 로고
    • The JAZ family of repressors is the missing link in jasmonate signalling
    • Chini A., Fonseca S., Fernández G., Adie B., Chico J.M., Lorenzo O., et al. The JAZ family of repressors is the missing link in jasmonate signalling. Nature 2007, 448:659-660.
    • (2007) Nature , vol.448 , pp. 659-660
    • Chini, A.1    Fonseca, S.2    Fernández, G.3    Adie, B.4    Chico, J.M.5    Lorenzo, O.6
  • 43
    • 0030305457 scopus 로고    scopus 로고
    • A language for data analysis and graphics
    • Ihaka R., Gentleman R. A language for data analysis and graphics. J Comput Graphical Stat 1996, 5:299-314.
    • (1996) J Comput Graphical Stat , vol.5 , pp. 299-314
    • Ihaka, R.1    Gentleman, R.2
  • 44
    • 77954275723 scopus 로고    scopus 로고
    • ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems
    • Kaimal V., Bardes E.E., Tabar S.C., Jegga A.G., Aronow B.J. ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems. Nucleic Acids Res 2010, 38:96-102.
    • (2010) Nucleic Acids Res , vol.38 , pp. 96-102
    • Kaimal, V.1    Bardes, E.E.2    Tabar, S.C.3    Jegga, A.G.4    Aronow, B.J.5
  • 47
    • 79960559808 scopus 로고    scopus 로고
    • Sequential minimal optimization: a fast algorithm for training support vector machines. Microsoft research technical report, MSR-TR-98-14.
    • Platt J. Sequential minimal optimization: a fast algorithm for training support vector machines. Microsoft research technical report, MSR-TR-98-14; 1998.
    • (1998)
    • Platt, J.1
  • 48
    • 34248177279 scopus 로고    scopus 로고
    • How high is the level of technical noise in microarray data?
    • Klebanov L., Yakovlev A. How high is the level of technical noise in microarray data?. Biol Direct 2007, 2:9.
    • (2007) Biol Direct , vol.2 , pp. 9
    • Klebanov, L.1    Yakovlev, A.2
  • 49
    • 77954168391 scopus 로고    scopus 로고
    • Effect of training-sample size and classification difficulty on the accuracy of genomic predictors
    • Popovici V., Chen W., Gallas B.G., Hatzis C., Shi W., Samuelson F.W., et al. Effect of training-sample size and classification difficulty on the accuracy of genomic predictors. Breast Cancer Res 2010, 12:R5.
    • (2010) Breast Cancer Res , vol.12
    • Popovici, V.1    Chen, W.2    Gallas, B.G.3    Hatzis, C.4    Shi, W.5    Samuelson, F.W.6
  • 51
    • 0033026857 scopus 로고    scopus 로고
    • Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide?
    • Siow R.C., Sato H., Mann G.E. Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide?. Cardiovasc Res 1999, 41:385-394.
    • (1999) Cardiovasc Res , vol.41 , pp. 385-394
    • Siow, R.C.1    Sato, H.2    Mann, G.E.3
  • 52
    • 0033778909 scopus 로고    scopus 로고
    • Heat shock factor 2 is activated during mouse heart development
    • Eriksson M., Jokinen E., Sistonen L., Leppä S. Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol 2000, 44:471-477.
    • (2000) Int J Dev Biol , vol.44 , pp. 471-477
    • Eriksson, M.1    Jokinen, E.2    Sistonen, L.3    Leppä, S.4
  • 53
    • 79960554400 scopus 로고    scopus 로고
    • Significance of the transcription factor Klf5 in myocardial hypertrophy in response to pressure overload
    • Takeda N., Manabe I., Uchino Y., Nagai R. Significance of the transcription factor Klf5 in myocardial hypertrophy in response to pressure overload. Circulation 2008, 118:S_431.
    • (2008) Circulation , vol.118
    • Takeda, N.1    Manabe, I.2    Uchino, Y.3    Nagai, R.4
  • 55
    • 33845485056 scopus 로고    scopus 로고
    • A quantitative gene expression profile of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) in the myocardium of patients with deteriorating heart failure requiring left ventricular assist device support
    • Felkin L.E., Birks E.J., George R., Wong S., Khaghani A., Yacoub M.H., et al. A quantitative gene expression profile of matrix metalloproteinases (MMPS) and their inhibitors (TIMPS) in the myocardium of patients with deteriorating heart failure requiring left ventricular assist device support. J Heart Lung Transplant 2006, 25:1413-1419.
    • (2006) J Heart Lung Transplant , vol.25 , pp. 1413-1419
    • Felkin, L.E.1    Birks, E.J.2    George, R.3    Wong, S.4    Khaghani, A.5    Yacoub, M.H.6
  • 56
    • 48549094895 scopus 로고    scopus 로고
    • A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
    • Statnikov L., Wang C.F., Aliferis A. A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification. BMC Bioinform 2008, 9:319.
    • (2008) BMC Bioinform , vol.9 , pp. 319
    • Statnikov, L.1    Wang, C.F.2    Aliferis, A.3
  • 57
    • 44449145580 scopus 로고    scopus 로고
    • A comparative study of different machine learning methods on microarray gene expression data
    • Pirooznia M., Yang J.Y., Yang M.Q., Deng Y. A comparative study of different machine learning methods on microarray gene expression data. BMC Genomics 2008, 9.
    • (2008) BMC Genomics , vol.9
    • Pirooznia, M.1    Yang, J.Y.2    Yang, M.Q.3    Deng, Y.4
  • 58
    • 77952007626 scopus 로고    scopus 로고
    • Coordinated modular functionality and prognostic potential of a heart failure biomarker-driven interaction network
    • Azuaje F., Devaux Y., Wagner D.R. Coordinated modular functionality and prognostic potential of a heart failure biomarker-driven interaction network. BMC Syst Biol 2010, 4:6.
    • (2010) BMC Syst Biol , vol.4 , pp. 6
    • Azuaje, F.1    Devaux, Y.2    Wagner, D.R.3
  • 59
    • 77956262458 scopus 로고    scopus 로고
    • Transcriptional networks characterize ventricular dysfunction after myocardial infarction: a proof-of-concept investigation
    • Azuaje F., Devaux Y., Vausort M., Yvorra C., Wagner D.R. Transcriptional networks characterize ventricular dysfunction after myocardial infarction: a proof-of-concept investigation. J Biomed Inform 2010, 43:812-819.
    • (2010) J Biomed Inform , vol.43 , pp. 812-819
    • Azuaje, F.1    Devaux, Y.2    Vausort, M.3    Yvorra, C.4    Wagner, D.R.5
  • 60
    • 43149116763 scopus 로고    scopus 로고
    • Gene-set approach for expression pattern analysis
    • Nam D., Kim S.Y. Gene-set approach for expression pattern analysis. Brief Bioinform 2008, 9:189-197.
    • (2008) Brief Bioinform , vol.9 , pp. 189-197
    • Nam, D.1    Kim, S.Y.2
  • 61
    • 13444249852 scopus 로고    scopus 로고
    • Prediction of cancer outcome with microarrays: a multiple random validation strategy
    • Michiels S., Koscielny S., Hill C. Prediction of cancer outcome with microarrays: a multiple random validation strategy. Lancet 2005, 365:488-492.
    • (2005) Lancet , vol.365 , pp. 488-492
    • Michiels, S.1    Koscielny, S.2    Hill, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.