Small-molecule displacement of a cryptic degron causes conditional protein degradation

Nature Chemical Biology

Volumn 7, Issue 8, 2011, Pages 531-537

  Bonger, Kimberly M ^a   Chen, Ling Chun ^a   Liu, Corey W ^a   Wandless, Thomas J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DEGRON; FK 506 RAPAMYCIN BINDING PROTEIN FUSION PROTEIN; HYBRID PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; LIGAND INDUCED DEGRADATION DOMAIN; MOUSE; MULTICENTER STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION;

EID: 79960559614     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.598     Document Type: Article

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