Synthesis of modified steroids as a novel class of non-ulcerogenic, anti-inflammatory and anti-nociceptive agents

Steroids

Volumn 76, Issue 10-11, 2011, Pages 1190-1203

  Mohareb, Rafat M ^a,b   Elmegeed, Gamal A ^c   Abdel Salam, Omar M E ^c   Doss, Senot H ^c   William, Marian G ^c  

^a OCTOBER UNIVERSITY FOR MODERN SCIENCES AND ARTS MSA   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Anti inflammatory; Anti nociceptive; Anti ulcerogenic; Azoles; Epoxids; Oxarine

Indexed keywords

17 (3' BENZOYL 2' METHYLOXIRAN 2' YL)ANDROST 4 ENE 3 ONE; 17 (4',5' DIHYDRO 3' HYDROXY 5' METHYL 4' PHENYLAMINO 1' PHENYLPYRAZOL 5' YL)ANDROST 4 ENE 3 ONE; 17 [4',5' DIHYDRO 3',5' DIMETHYL 4' (4 CHLOROPHENYLAMINO) 1' PHENYLPYRAZOL 5' YL]ANDROST 4 ENE 3 ONE; 20 HYDROXY 20 [1',3', 4' TRIPHENYL 2' THIOXO 1',3' IMIDAZOL 5' YL]PREGN 4 ENE 3 ONE; CARRAGEENAN; INDOMETACIN; STEROID; TRAMADOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ANTIULCEROGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; IN VIVO STUDY; NONHUMAN; PAIN; PAW EDEMA; RAT; STEROIDOGENESIS; STOMACH LESION; STOMACH ULCER; STRUCTURE ACTIVITY RELATION; THERMAL PAIN;

ACETIC ACID; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; AZOLES; CARRAGEENAN; EDEMA; MICE; PAIN; RATS; STEROIDS;

RATTUS;

EID: 79960439510     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.05.011     Document Type: Article

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