Synthesis of 3α-hydroxy-21-(1′-imidazolyl)-3β-methoxyl- methyl-5α-pregnan-20-one via lithium imidazole with 17α- acetylbromopregnanone

Steroids

Volumn 71, Issue 1, 2006, Pages 77-82

  Wong, Fung Fuh ^a   Chen, Chun Yen ^a   Chen, Tse Hsin ^a   Huang, Jiann Jyh ^b   Fang, Hsiao Ping ^c   Yeh, Mou Yung ^a,d  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b DEVELOPMENT CENTER FOR BIOTECHNOLOGY   (Taiwan)

^c ScinoPharm Biotech Ltd   (Taiwan)

^d NAN JEON INSTITUTE OF TECHNOLOGY   (Taiwan)

Author keywords

1,3 Disubstituted imidazolium salt; Bromination; Epoxidation; Hydrogenation; Oxidation; Ring opening reaction

Indexed keywords

17ALPHA ACETYLBROMOPREGNANONE; 3ALPHA HYDROXY 21 (1' IMIDAZOLYL) 3BETA METHOXYMETHYL 5ALPHA PREGNAN 20 ONE; ACETIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; LITHIUM IMIDAZOLE; PREGNANE DERIVATIVE; STEROID; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ELTANOLONE; IMIDAZOLE;

ARTICLE; DRUG SYNTHESIS; STEREOCHEMISTRY; CHEMISTRY; HYDROGENATION; OXIDATION REDUCTION REACTION; SYNTHESIS; TEMPERATURE;

HYDROGENATION; IMIDAZOLES; OXIDATION-REDUCTION; PREGNANOLONE; TEMPERATURE;

EID: 28544452254     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2005.08.006     Document Type: Article

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