Synthesis and antinociceptive activity of pyrazolyl isoxazolines and pyrazolyl isoxazoles

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 13, 2009, Pages 3370-3373

  Karthikeyan, K ^a   Veenus Seelan, T ^b   Lalitha, K G ^b   Perumal, P T ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^b Ultra College of Pharmacy   (India)

Author keywords

1,3 Dipolar cycloaddition; Antinociceptive activity; Pyrazolyl isoxazole; Pyrazolyl isoxazoline

Indexed keywords

3 PYRAZOLYL 4,5 DICARBETHOXYISOXAZOLE DERIVATIVE; ACETYLSALICYLIC ACID; DIETHYLACETYLENE DICARBOXYLATE; ISOXAZOLE DERIVATIVE; ISOXAZOLINE DERIVATIVE; MALEIMIDE DERIVATIVE; NITRILE OXIDE; PENTAZOCINE; PHENYLACETYLENE; PYRAZOLYLISOXAZOLE DERIVATIVE; PYRAZOLYLISOXAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; CYCLOADDITION; DRUG SYNTHESIS; NONHUMAN; PRODUCT RECOVERY; RAT; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TAIL FLICK TEST;

ADMINISTRATION, ORAL; ANALGESICS; ANIMALS; CYCLIZATION; ISOXAZOLES; MICE; PYRAZOLES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 66349130095     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.05.055     Document Type: Article

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