Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells

Journal of Experimental Medicine

Volumn 208, Issue 7, 2011, Pages 1351-1358

  Naik, Edwina ^a,b   O'Reilly, Lorraine A ^a   Asselin Labat, Marie Liesse ^a,b   Merino, Delphine ^a   Lin, Ann ^a   Cook, Michele ^a   Coultas, Leigh ^a,b   Bouillet, Philippe ^a,b   Adams, Jerry M ^a,b   Strasser, Andreas ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; BIM PROTEIN; GANCICLOVIR; VASCULOTROPIN A; VASCULOTROPIN INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; ENDOTHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR VASCULARIZATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; ENDOTHELIAL CELLS; GANCICLOVIR; GENE EXPRESSION; MELANOMA, EXPERIMENTAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; THYMIDINE KINASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79960370837     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100951     Document Type: Article

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