메뉴 건너뛰기




Volumn 410, Issue 5, 2011, Pages 972-983

Celastrol inhibits tat-mediated human immunodeficiency virus (HIV) transcription and replication

Author keywords

Cys domain; interaction; Michael acceptors; natural products

Indexed keywords

CELASTROL; CURCUMIN; GAMBOGIC ACID; ROSMARINIC ACID; TRANSACTIVATOR PROTEIN;

EID: 79960351591     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.04.013     Document Type: Article
Times cited : (47)

References (51)
  • 1
    • 33748159867 scopus 로고    scopus 로고
    • Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription
    • Agbottah E.; Deng L.; Dannenberg L.O.; Pumfery A.; and Kashanchi F. Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription Retrovirology 3 2006 48
    • (2006) Retrovirology , vol.3 , pp. 48
    • Agbottah, E.1    Deng, L.2    Dannenberg, L.O.3    Pumfery, A.4    Kashanchi, F.5
  • 3
    • 0034040118 scopus 로고    scopus 로고
    • Reservoirs for HIV-1: Mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy
    • DOI 10.1146/annurev.immunol.18.1.665
    • Pierson T.; McArthur J.; and Siliciano R.F. Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy Annu. Rev. Immunol. 18 2000 665 708 (Pubitemid 30365394)
    • (2000) Annual Review of Immunology , vol.18 , pp. 665-708
    • Pierson, T.1    McArthur, J.2    Siliciano, R.F.3
  • 4
    • 0347951395 scopus 로고    scopus 로고
    • Regulation of HIV-1 gene transcription: From lymphocytes to microglial cells
    • DOI 10.1189/jlb.0403180
    • Rohr O.; Marban C.; Aunis D.; and Schaeffer E. Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells J. Leukoc. Biol. 74 2003 736 749 (Pubitemid 38040350)
    • (2003) Journal of Leukocyte Biology , vol.74 , Issue.5 , pp. 736-749
    • Rohr, O.1    Marban, C.2    Aunis, D.3    Schaeffer, E.4
  • 5
    • 0025248378 scopus 로고
    • HIV-1 tat protein trans-activates transcription in vitro
    • Marciniak R.A.; Calnan B.J.; Frankel A.D.; and Sharp P.A. HIV-1 Tat protein trans-activates transcription in vitro Cell 63 1990 791 802 (Pubitemid 120035052)
    • (1990) Cell , vol.63 , Issue.4 , pp. 791-802
    • Marciniak, R.A.1    Calnan, B.J.2    Frankel, A.D.3    Sharp, P.A.4
  • 7
    • 0032701796 scopus 로고    scopus 로고
    • Tackling Tat
    • DOI 10.1006/jmbi.1999.3060
    • Karn J. Tackling Tat J. Mol. Biol. 293 1999 235 254 (Pubitemid 29516167)
    • (1999) Journal of Molecular Biology , vol.293 , Issue.2 , pp. 235-254
    • Karn, J.1
  • 8
    • 0022003610 scopus 로고
    • Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat
    • Sodroski J.; Rosen C.; Wong-Staal F.; Salahuddin S.Z.; Popovic M.; and Arya S. Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat Science 227 1985 171 173 (Pubitemid 15154221)
    • (1985) Science , vol.227 , Issue.4683 , pp. 171-173
    • Sodroski, J.1    Rosen, C.2    Wong-Staal, F.3
  • 10
    • 0025168740 scopus 로고
    • Fragments of the HIV-1 Tat protein specifically bind TAR RNA
    • Weeks K.M.; Ampe C.; Schultz S.C.; Steitz T.A.; and Crothers D.M. Fragments of the HIV-1 Tat protein specifically bind TAR RNA Science 249 1990 1281 1285
    • (1990) Science , vol.249 , pp. 1281-1285
    • Weeks, K.M.1    Ampe, C.2    Schultz, S.C.3    Steitz, T.A.4    Crothers, D.M.5
  • 11
  • 12
    • 0036150085 scopus 로고    scopus 로고
    • Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences
    • DOI 10.1128/MCB.22.4.1079-1093.2002
    • Bourgeois C.F.; Kim Y.K.; Churcher M.J.; West M.J.; and Karn J. Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences Mol. Cell. Biol. 22 2002 1079 1093 (Pubitemid 34094845)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.4 , pp. 1079-1093
    • Bourgeois, C.F.1    Kim, Y.K.2    Churcher, M.J.3    West, M.J.4    Karn, J.5
  • 13
    • 0342748478 scopus 로고    scopus 로고
    • Domains in the SPT5 protein that modulate its transcriptional regulatory properties
    • DOI 10.1128/MCB.20.9.2970-2983.2000
    • Ivanov D.; Kwak Y.T.; Guo J.; and Gaynor R.B. Domains in the SPT5 protein that modulate its transcriptional regulatory properties Mol. Cell. Biol. 20 2000 2970 2983 (Pubitemid 30215010)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.9 , pp. 2970-2983
    • Ivanov, D.1    Kwak, Y.T.2    Guo, J.3    Gaynor, R.B.4
  • 14
    • 18144372773 scopus 로고    scopus 로고
    • Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5
    • Ping Y.H.; Chu C.Y.; Cao H.; Jacque J.M.; Stevenson M.; and Rana T.M. Modulating HIV-1 replication by RNA interference directed against human transcription elongation factor SPT5 Retrovirology 1 2004 46
    • (2004) Retrovirology , vol.1 , pp. 46
    • Ping, Y.H.1    Chu, C.Y.2    Cao, H.3    Jacque, J.M.4    Stevenson, M.5    Rana, T.M.6
  • 15
    • 0035918157 scopus 로고    scopus 로고
    • DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
    • Ping Y.H.; and Rana T.M. DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation J. Biol. Chem. 276 2001 12951 12958
    • (2001) J. Biol. Chem. , vol.276 , pp. 12951-12958
    • Ping, Y.H.1    Rana, T.M.2
  • 16
    • 0023513563 scopus 로고
    • Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
    • DOI 10.1038/330489a0
    • Kao S.Y.; Calman A.F.; Luciw P.A.; and Peterlin B.M. Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product Nature 330 1987 489 493 (Pubitemid 18006431)
    • (1987) Nature , vol.330 , Issue.6147 , pp. 489-493
    • Kao, S.-Y.1    Calman, A.F.2    Luciw, P.A.3    Peterlin, B.M.4
  • 17
    • 0026064723 scopus 로고
    • HIV-1 Tat protein promotes formation of more-processive elongation complexes
    • Marciniak R.A.; and Sharp P.A. HIV-1 Tat protein promotes formation of more-processive elongation complexes EMBO J. 10 1991 4189 4196 (Pubitemid 21905451)
    • (1991) EMBO Journal , vol.10 , Issue.13 , pp. 4189-4196
    • Marciniak, R.A.1    Sharp, P.A.2
  • 18
    • 0025721104 scopus 로고
    • Tat transactivation of the human immunodeficiency virus type 1 promoter is influenced by basal promoter activity and the simian virus 40 origin of DNA replication
    • Kessler M.; and Mathews M.B. Tat transactivation of the human immunodeficiency virus type 1 promoter is influenced by basal promoter activity and the simian virus 40 origin of DNA replication Proc. Natl Acad. Sci. USA 88 1991 10018 10022 (Pubitemid 21915766)
    • (1991) Proceedings of the National Academy of Sciences of the United States of America , vol.88 , Issue.22 , pp. 10018-10022
    • Kessler, M.1    Mathews, M.B.2
  • 19
    • 34447122581 scopus 로고    scopus 로고
    • Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex
    • DOI 10.1074/jbc.M610688200
    • Zhang Z.; Klatt A.; Gilmour D.S.; and Henderson A.J. Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex J. Biol. Chem. 282 2007 16981 16988 (Pubitemid 47093194)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.23 , pp. 16981-16988
    • Zhang, Z.1    Klatt, A.2    Gilmour, D.S.3    Henderson, A.J.4
  • 20
    • 0024414213 scopus 로고
    • HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation
    • DOI 10.1016/0092-8674(89)90290-0
    • Laspia M.F.; Rice A.P.; and Mathews M.B. HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation Cell 59 1989 283 292 (Pubitemid 19264374)
    • (1989) Cell , vol.59 , Issue.2 , pp. 283-292
    • Laspia, M.F.1    Rice, A.P.2    Mathews, M.B.3
  • 22
    • 0024591269 scopus 로고
    • Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis
    • Kuppuswamy M.; Subramanian T.; Srinivasan A.; and Chinnadurai G. Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis Nucleic Acids Res. 17 1989 3551 3561 (Pubitemid 19120452)
    • (1989) Nucleic Acids Research , vol.17 , Issue.9 , pp. 3551-3561
    • Kuppuswamy, M.1    Subramanian, T.2    Srinivasan, A.3    Chinnadurai, G.4
  • 23
    • 57749099233 scopus 로고    scopus 로고
    • Thioredoxin reductase-1 negatively regulates HIV-1 transactivating protein Tat-dependent transcription in human macrophages
    • Kalantari P.; Narayan V.; Natarajan S.K.; Muralidhar K.; Gandhi U.H.; and Vunta H. Thioredoxin reductase-1 negatively regulates HIV-1 transactivating protein Tat-dependent transcription in human macrophages J. Biol. Chem. 283 2008 33183 33190
    • (2008) J. Biol. Chem. , vol.283 , pp. 33183-33190
    • Kalantari, P.1    Narayan, V.2    Natarajan, S.K.3    Muralidhar, K.4    Gandhi, U.H.5    Vunta, H.6
  • 24
    • 0030220697 scopus 로고    scopus 로고
    • Cloning, high-yield expression in Escherichia coli, and purification of biologically active HIV-1 Tat protein
    • DOI 10.1006/prep.1996.0076
    • Kirsch T.; Boehm M.; Schuckert O.; Metzger A.U.; Willbold D.; Frank R.W.; and Rosch P. Cloning, high-yield expression in Escherichia coli, and purification of biologically active HIV-1 Tat protein Protein Expression Purif. 8 1996 75 84 (Pubitemid 26326215)
    • (1996) Protein Expression and Purification , vol.8 , Issue.1 , pp. 75-84
    • Kirsch, T.1    Boehm, M.2    Schuckert, O.3    Metzger, A.U.4    Willbold, D.5    Frank, R.W.6    Rosch, P.7
  • 26
    • 59549100246 scopus 로고    scopus 로고
    • Boosted protease inhibitor-based or nonnucleoside reverse transcriptase-based HAART: Is there a best choice for antiretroviral-naive HIV-1 infected patients?
    • Cuzin L.; Allavena C.; Morlat P.; and Dellamonica P. Boosted protease inhibitor-based or nonnucleoside reverse transcriptase-based HAART: is there a best choice for antiretroviral-naive HIV-1 infected patients? AIDS Rev. 10 2008 205 211
    • (2008) AIDS Rev. , vol.10 , pp. 205-211
    • Cuzin, L.1    Allavena, C.2    Morlat, P.3    Dellamonica, P.4
  • 28
    • 0036027897 scopus 로고    scopus 로고
    • Human immunodeficiency virus and host cell lipids. Interesting pathways in research for a new HIV therapy
    • DOI 10.1016/S0163-7827(01)00019-4, PII S0163782701000194
    • Raulin J. Human immunodeficiency virus and host cell lipids. Interesting pathways in research for a new HIV therapy Prog. Lipid Res. 41 2002 27 65 (Pubitemid 32994811)
    • (2002) Progress in Lipid Research , vol.41 , Issue.1 , pp. 27-65
    • Raulin, J.1
  • 30
    • 0036742473 scopus 로고    scopus 로고
    • Screening of selected plant extracts for in vitro inhibitory activity on human immunodeficiency virus
    • Bedoya L.M.; Palomino S.S.; Abad M.J.; Bermejo P.; and Alcami J. Screening of selected plant extracts for in vitro inhibitory activity on human immunodeficiency virus Phytother. Res. 16 2002 550 554
    • (2002) Phytother. Res. , vol.16 , pp. 550-554
    • Bedoya, L.M.1    Palomino, S.S.2    Abad, M.J.3    Bermejo, P.4    Alcami, J.5
  • 32
    • 0031976901 scopus 로고    scopus 로고
    • Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat
    • DOI 10.1016/S0923-2516(97)86899-9
    • Barthelemy S.; Vergnes L.; Moynier M.; Guyot D.; Labidalle S.; and Bahraoui E. Curcumin and curcumin derivatives inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat Res. Virol. 149 1998 43 52 (Pubitemid 28162429)
    • (1998) Research in Virology , vol.149 , Issue.1 , pp. 43-52
    • Barthelemy, S.1    Vergnes, L.2    Moynier, M.3    Guyot, D.4    Labidalle, S.5    Bahraoui, E.6
  • 33
    • 0034192164 scopus 로고    scopus 로고
    • Identification of the real molecular target for HIV inhibitors [2]
    • DOI 10.1016/S0165-6147(00)01461-9, PII S0165614700014619
    • De Clercq E. Identification of the real molecular target for HIV inhibitors Trends Pharmacol. Sci. 21 2000 167 168 (Pubitemid 30243195)
    • (2000) Trends in Pharmacological Sciences , vol.21 , Issue.5 , pp. 167-168
    • De Clercq, E.1
  • 34
    • 43049131793 scopus 로고    scopus 로고
    • Reaction of rosmarinic acid with nitrite ions in acidic conditions: Discovery of nitro- and dinitrorosmarinic acids as new anti-HIV-1 agents
    • DOI 10.1021/jm7011134
    • Dubois M.; Bailly F.; Mbemba G.; Mouscadet J.F.; Debyser Z.; Witvrouw M.; and Cotelle P. Reaction of rosmarinic acid with nitrite ions in acidic conditions: discovery of nitro- and dinitrorosmarinic acids as new anti-HIV-1 agents J. Med. Chem. 51 2008 2575 2579 (Pubitemid 351628520)
    • (2008) Journal of Medicinal Chemistry , vol.51 , Issue.8 , pp. 2575-2579
    • Dubois, M.1    Bailly, F.2    Mbemba, G.3    Mouscadet, J.-F.4    Debyser, Z.5    Witvrouw, M.6    Cotelle, P.7
  • 36
    • 20644442241 scopus 로고    scopus 로고
    • Active site binding modes of curcumin in HIV-1 protease and integrase
    • DOI 10.1016/j.bmcl.2005.05.032, PII S0960894X05006165
    • Vajragupta O.; Boonchoong P.; Morris G.M.; and Olson A.J. Active site binding modes of curcumin in HIV-1 protease and integrase Bioorg. Med. Chem. Lett. 15 2005 3364 3368 (Pubitemid 40835737)
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , Issue.14 , pp. 3364-3368
    • Vajragupta, O.1    Boonchoong, P.2    Morris, G.M.3    Olson, A.J.4
  • 41
    • 0342742310 scopus 로고
    • Tumor necrosis factor α and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB
    • DOI 10.1073/pnas.86.7.2336
    • Osborn L.; Kunkel S.; and Nabel G.J. Tumor necrosis factor α and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB Proc. Natl Acad. Sci. USA 86 1989 2336 2340 (Pubitemid 19102503)
    • (1989) Proceedings of the National Academy of Sciences of the United States of America , vol.86 , Issue.7 , pp. 2336-2340
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 42
    • 0037718417 scopus 로고    scopus 로고
    • Inhibition of HIV Tat-TAR interactions by an antisense oligo-2′-O-methylribonucleoside methylphosphonate
    • DOI 10.1016/S0960-894X(03)00323-8
    • Hamma T.; Saleh A.; Huq I.; Rana T.M.; and Miller P.S. Inhibition of HIV tat-TAR interactions by an antisense oligo-2′-O-methylribonucleoside methylphosphonate Bioorg. Med. Chem. Lett. 13 2003 1845 1848 (Pubitemid 36577125)
    • (2003) Bioorganic and Medicinal Chemistry Letters , vol.13 , Issue.11 , pp. 1845-1848
    • Hamma, T.1    Saleh, A.2    Huq, I.3    Rana, T.M.4    Miller, P.S.5
  • 44
    • 64249171904 scopus 로고    scopus 로고
    • Gambogic acid covalently modifies IκB kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages
    • Palempalli U.D.; Gandhi U.; Kalantari P.; Vunta H.; Arner R.J.; and Narayan V. Gambogic acid covalently modifies IκB kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages Biochem. J. 419 2009 401 409
    • (2009) Biochem. J. , vol.419 , pp. 401-409
    • Palempalli, U.D.1    Gandhi, U.2    Kalantari, P.3    Vunta, H.4    Arner, R.J.5    Narayan, V.6
  • 45
    • 23644436829 scopus 로고    scopus 로고
    • 2 by nuclear factor-kappa B and other cellular proteins
    • DOI 10.1016/j.bmcl.2005.06.025, PII S0960894X05007638
    • 2 by nuclear factor-kappa B and other cellular proteins Bioorg. Med. Chem. Lett. 15 2005 4057 4063 (Pubitemid 41132661)
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , Issue.18 , pp. 4057-4063
    • Pande, V.1    Ramos, M.J.2
  • 48
    • 0034610759 scopus 로고    scopus 로고
    • Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
    • DOI 10.1038/47520
    • Rossi A.; Kapahi P.; Natoli G.; Takahashi T.; Chen Y.; Karin M.; and Santoro M.G. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase Nature 403 2000 103 108 (Pubitemid 30038530)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 103-108
    • Rossi, A.1    Kapahi, P.2    Natoli, G.3    Takahashi, T.4    Chen, Y.5    Karin, M.6    Santoro, M.G.7
  • 50
    • 0029156755 scopus 로고
    • C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes
    • Henderson A.J.; Zou X.; and Calame K.L. C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes J. Virol. 69 1995 5337 5344
    • (1995) J. Virol. , vol.69 , pp. 5337-5344
    • Henderson, A.J.1    Zou, X.2    Calame, K.L.3
  • 51
    • 0029966369 scopus 로고    scopus 로고
    • HIV-1 tat protein and its inhibitor ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors
    • DOI 10.1006/cimm.1996.0088
    • Patki A.H.; and Lederman M.M. HIV-1 Tat protein and its inhibitor Ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors Cell. Immunol. 169 1996 40 46 (Pubitemid 26124614)
    • (1996) Cellular Immunology , vol.169 , Issue.1 , pp. 40-46
    • Patki, A.H.1    Lederman, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.