Pharmacology and in vitro profiling of a novel peroxisome proliferator-activated receptor γ ligand, cerco-A

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 7, 2011, Pages 1094-1104

  Wakabayashi, Kenji ^a,b   Hayashi, Shinko ^b   Matsui, Yumi ^b   Matsumoto, Takuo ^b   Furukawa, Akihiro ^b   Kuroha, Masanori ^b   Tanaka, Naomi ^b   Inaba, Tomoko ^b   Kanda, Shoichi ^b   Tanaka, Jun ^b   Okuyama, Ryo ^b   Wakimoto, Satoko ^b   Ogata, Tsuneaki ^b   Araki, Kazushi ^b   Ohsumi, Jun ^b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Diabetes; Modulator; Partial agonist; Peroxisome proliferator activated receptor

Indexed keywords

5 [4 [[6 (4 HYDROXY 3,5 DIMETHYLPHENOXY) 1 METHYL 1H BENZIMIDAZOL 2 YL]METHOXY]BENZYL] 1,3 THIAZOLIDINE 2,4 DIONE; CERCO A; GLITAZONE DERIVATIVE; GLUCOSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; ROSIGLITAZONE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADVERSE OUTCOME; ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING ASSAY; CARDIOMEGALY; CELL ASSAY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIABETES MELLITUS; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEMODILUTION; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ADIPOCYTES; ANIMALS; BASE SEQUENCE; BENZOFURANS; CELL DIFFERENTIATION; CELL LINE, TUMOR; DNA PRIMERS; FLUORESCENCE POLARIZATION; HUMANS; LIGANDS; MOLECULAR STRUCTURE; PPAR GAMMA; RATS; RATS, ZUCKER;

EID: 79960331940     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.1094     Document Type: Article

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