Changes in the contents of enzymatic immature, mature, and non-enzymatic senescent cross-links of collagen after once-weekly treatment with human parathyroid hormone (1-34) for 18 months contribute to improvement of bone strength in ovariectomized monkeys

Osteoporosis International

Volumn 22, Issue 8, 2011, Pages 2373-2383

  Saito, M ^a   Marumo, K ^a   Kida, Y ^a   Ushiku, C ^a   Kato, S ^a   Takao Kawabata, R ^b   Kuroda, T ^b  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ASAHI KASEI PHARMA CORPORATION   (Japan)

Author keywords

Advanced glycation end products; Bone strength; Collagen; Cross links; hPTH(1 34); OVX primate model

Indexed keywords

COLLAGEN; PARATHYROID HORMONE[1-34]; PENTOSIDINE;

ANIMAL EXPERIMENT; ARTICLE; BONE MINERALIZATION; BONE STRENGTH; CANCELLOUS BONE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MEGADOSE; FEMALE; LOW DRUG DOSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RIGIDITY; SENESCENCE; TRABECULAR BONE; TREATMENT DURATION;

ANIMALS; ARGININE; BONE DENSITY; BONE DENSITY CONSERVATION AGENTS; CALCIUM; COLLAGEN; COMPRESSIVE STRENGTH; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; FEMALE; GLYCOSYLATION END PRODUCTS, ADVANCED; LUMBAR VERTEBRAE; LYSINE; MACACA FASCICULARIS; OSTEOPOROSIS; OVARIECTOMY; PHOSPHATES; TERIPARATIDE; X-RAY MICROTOMOGRAPHY;

EID: 79960276545     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-010-1454-4     Document Type: Article

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