Fluoxetine affects GluK2 editing, glutamate-evoked Ca2+ influx and extracellular signal-regulated kinase phosphorylation in mouse astrocytes

Journal of Psychiatry and Neuroscience

Volumn 36, Issue 5, 2011, Pages 322-338

  Li, Baoman ^a   Zhang, Shiquen ^a   Zhang, Hongyan ^a   Hertz, Leif ^a   Peng, Liang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; COMPLEMENTARY DNA; FLUOXETINE; GLUTAMIC ACID; KAINIC ACID RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SEROTONIN RECEPTOR; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SEQUENCE; DRUG EFFECT; ENZYME PHOSPHORYLATION; ENZYME SUBUNIT; FLUOROMETRY; GENE AMPLIFICATION; MALE; MOUSE; NERVE CELL CULTURE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EDITING; UPREGULATION; WESTERN BLOTTING;

EID: 79960264066     PISSN: 11804882     EISSN: 14882434     Source Type: Journal    
DOI: 10.1503/jpn.100094     Document Type: Article

References (68)

1. Rao JS, Ertley RN, Lee HJ, et al. Chronic fluoxetine up-regulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex. Pharmacogenomics J 2006;6:413-20.
2. Li B, Zhang S, Li M, et al. Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA(2) expression secondary to 5-HT (2B)-induced, transactivation-mediated ERK (1/2) phosphorylation. Psychopharmacology (Berl) 2009a;207:1-12.
3. Zhang S, Li B, Lovatt D, et al. 5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors.' Neuron Glia Biol 2010;6:113-25.
4. Li B, Zhang S, Zhang H, et al. Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation. Psychopharmacology (Berl) 2008;201:443-58.
5. Kong EKC, Peng L, Chen Y, et al. Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration. Neurochem Res 2002;27: 113-20.
6. Yu PH, Hertz L. Differential expression of type A and type B monoamine oxidase of mouse astrocytes in primary cultures. J Neurochem 1982;39:1492-5.
7. Yu PH, Hertz L. Type A and B monoamine oxidase in glial cells in long term culture. Prog Neuropsychopharmacol Biol Psychiatry 1983;7: 687-90.
8. Barbon A, Popoli M, La Via L, et al. Regulation of editing and expression of glutamate alpha-amino-propionic-acid (AMPA)/kainate receptors by antidepressant drugs. Biol Psychiatry 2006;59:713-20.
9. Bass BL. RNA editing by adenosine deaminases that act on RNA. Annu Rev Biochem 2002;71:817-46.
10. Valente L, Nishikura K. ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation. Prog Nucleic Acid Res Mol Biol 2005;79:299-338.
11. Kawahara Y, Ito K, Sun H, et al. Regulation of glutamate receptor RNA editing and ADAR mRNA expression in developing human normal and Down's syndrome brains. Dev Brain Res 2004; 148:151-5.
12. Köhr G, Melcher T, Seeburg PH. Candidate editases for GluR channels in single neurons of rat hippocampus and cerebellum. Neuropharmacology 1998;37:1411-7.
13. Rueter SM, Dawson TR, Emeson RB. Regulation of alternative splicing by RNA editing. Nature 1999;399:75-80.
14. Sergeeva OA, Amberger BT, Haas HL. Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Cell Mol Neurobiol 2007;27:669-80.
15. Maas S, Patt S, Schrey M, et al. Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc Natl Acad Sci U S A 2001; 98:14687-92.
16. Strutz-Seebohm N, Seebohm G, Shumilina E, et al. Glucocorticoid adrenal steroids and glucocorticoid-inducible kinase isoforms in the regulation of GluR6 expression. J Physiol 2005;565:391-401.
17. Brand-Schieber E, Lowery SL, Werner P. Select ionotropic glutamate AMPA/kainate receptors are expressed at the astrocyte-vessel interface. Brain Res 2004;1007:178-82.
18. Cahoy JD, Emery B, Kaushal A, et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci 2008;28:264-78.
19. Zarate CA Jr, Payne JL, Quiroz J, et al. An open-label trial of riluzole in patients with treatment-resistant major depression. Am J Psychiatry 2004;161:171-4.
20. Müller N, Schwarz MJ. The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression. Mol Psychiatry 2007;12:988-1000.
21. Machado-Vieira R, Salvadore G, Diazgranados N, et al. Ketamine and the next generation of antidepressants with a rapid onset of action. Pharmacol Ther 2009;123:143-50.
22. Hertz L, Zielke HR. Astrocytic control of glutamatergic activity: astrocytes as stars of the show. Trends Neurosci 2004;27:735-43.
23. Danbolt NC. Glutamate uptake. Prog Neurobiol 2001;65:1-105.
24. Halassa MM, Haydon PG. Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol 2010;72:335-55.
25. Kirchhoff AC, Leisenring W, Syrjala KL. Prospective predictors of return to work in the 5 years after hematopoietic cell transplantation. J Cancer Surviv 2010;4:33-44.
26. Laje G, Paddock S, Manji H, et al. Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry 2007;164:1530-8.
27. Menke A, Lucae S, Kloiber S, et al. Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation. Am J Psychiatry 2008;165:917-8.
28. Chen Y, Guo JJ, Steinbuch M, et al. Risk of neuroleptic malignant syndrome in patients with bipolar disorder: a retrospective, populationbased case-control study. Int J Psychiatry Med 2009;39:439-50.
29. Beneyto M, Kristiansen LV, Oni-Orisan A, et al. Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders. Neuropsychopharmacology 2007;32:1888-902.
30. Shaltiel G, Maeng S, Malkesman O, et al. Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry 2008;13:858-72.
31. Malkesman O, Austin DR, Chen G, et al. Reverse translational strategies for developing animal models of bipolar disorder. Dis Model Mech 2009;2:238-45.
32. Hertz L, Schousboe A, Boechler N, et al. Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures. Neurochem Res 1978;3:1-14.
33. Hertz L, Peng L, Lai JC. Functional studies in cultured astrocytes. Methods 1998;16:293-310.
34. Meier E, Hertz L, Schousboe A. Neurotransmitters as development - al signals. Neurochem Int 1991;19:1-15.
35. Hertz L, Juurlink BHJ, Szuchet S. Cell cultures. In: Lajtha A, editor. Handbook of neurochemistry. 2nd ed. New York (NY): Plenum; 1985.
36. Liang YJ, Lai LP, Wang BW, et al. Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes. Cardiovasc Res 2006;72: 303-12.
37. Wong SK, Lazinski DW. Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1. Proc Natl Acad Sci U S A 2002;99:15118-23.
38. Li B, Zhang S, Li M, et al. Down-regulation of GluK2 kainate receptor expression by chronic treatment with mood-stabilizing anticonvulsants or lithium in cultured astrocytes and brain, but not in neurons. Neuropharmacology 2009;57:375-85.
39. Bureau I, Dieudonne S, Coussen F, et al. Kainate receptormediated synaptic currents in cerebellar Golgi cells are not shaped by diffusion of glutamate. Proc Natl Acad Sci U S A 2000;97:6838-43.
40. Hong J, Qian Z, Shen S, et al. High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA inter ference in the mouse. Biochem J 2005;390:675-9.
41. Feng Y, Sansam CL, Singh M, et al. Altered RNA editing in mice lacking ADAR2 autoregulation. Mol Cell Biol 2006;26:480-8.
42. Sergeeva OA, Amberger BT, Haas HL. Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Cell Mol Neurobiol 2007;27:669-80.
43. el-Marjou A, Delouvée A, Thiery JP, et al. Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression. Carcinogenesis 2000;21:2211-8.
44. Ye S, Dhillon S, Ke X, et al. An efficient procedure for genotyping single nucleotide polymorphisms. Nucleic Acids Res 2001;29:E88.
45. Newton CR, Graham A, Heptinstall LE, et al. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 1989;17:2503-16.
46. Punia P, Saunders NA. The Quantitative amplification refractory mutation system. In: Logan J, Edwards K, Saunders N, editors. Real-time PCR: current technology and applications. Norfolk (VA): Horizon Scientific Press, Inc.; 2009.
47. Iwamoto K, Bundo M, Kato T. Estimating RNA editing efficiency of five editing sites in the serotonin 2C receptor by pyrosequencing. RNA 2005;11:1596-603.
48. Jane DE, Lodge D, Collingridge GL. Kainate receptors: pharmacology, function and therapeutic potential. Neuropharmacology 2009; 56:90-113.
49. Kim WT, Rioult MG, Cornell-Bell AH. Glutamate-induced calcium signaling in astrocytes. Glia 1994;11:173-84.
50. Shelton MK, McCarthy KD. Mature hippocampal astrocytes exhibit functional metabotropic and ionotropic glutamate receptors in situ. Glia 1999;26:1-11.
51. Barbon A, Popoli M, La Via L, et al. Regulation of editing and expression of glutamate alpha-amino-propionic-acid (AMPA)/kainate receptors by antidepressant drugs. Biol Psychiatry 2006;59:713-20.
52. Englander MT, Dulawa SC, Bhansali P, et al. How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing. J Neurosci 2005;25:648-51.
53. Köhler M, Burnashev N, Sakmann B, et al. Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: diversity by RNA editing. Neuron 1993;10:491-500.
54. Vissel B, Royle GA, Christie BR, et al. The role of RNA editing of kainate receptors in synaptic plasticity and seizures. Neuron 2001; 29:217-27.
55. Sommer B, Köhler M, Sprengel R, et al. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell 1991;67:11-9.
56. Schmitt J, Dux E, Gissel C, et al. Regional analysis of development - al changes in the extent of GluR6 mRNA editing in rat brain. Brain Res Dev Brain Res 1996;91:153-7.
57. Paschen W, Schmitt J, Gissel C, et al. Developmental changes of RNA editing of glutamate receptor subunits GluR5 and GluR6: in vivo versus in vitro. Dev Brain Res 1997;98:271-80.
58. Lowe DL, Jahn K, Smith DO. Glutamate receptor editing in the mammalian hippocampus and avian neurons. Brain Res Mol Brain Res 1997;48:37-44.
59. Bernard A, Ferhat L, Dessi F, et al. Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: evidence for independent developmental, pathological and cellular regulation. Eur J Neurosci 1999;11:604-16.
60. Lai F, Chen CX, Carter KC, et al. Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases. Mol Cell Biol 1997;17:2413-24.
61. Ko S, Zhao MG, Toyoda H, et al. Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice. J Neurosci 2005;25:977-84.
62. Choudary PV, Molnar M, Evans SJ, et al. Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. Proc Natl Acad Sci U S A 2005;102:15653-8.
63. Miguel-Hidalgo JJ, Waltzer R, Whittom AA, et al. Glial and glutamatergic markers in depression, alcoholism, and their comorbidity. J Affect Disord 2010 Jun 24. [Epub ahead of print]
64. Bernard R, Kerman IA, Thompson RC, et al. Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression. Mol Psychiatry 2010 Apr 13. [Epub ahead of print]
65. Bekar LK, He W, Nedergaard M. Locus coeruleus alpha-adrenergicmediated activation of cortical astrocytes in vivo. Cereb Cortex 2008;18:2789-95.
66. Mitchell ND, Baker GB. An update on the role of glutamate in the pathophysiology of depression. Acta Psychiatr Scand 2010;122:192-210.
67. Verkhratsky A, Kettenmann H. Calcium signalling in glial cells. Trends Neurosci 1996;19:346-52.
68. Halassa MM, Haydon PG. Integrated brain circuits: astrocytic networks modulate neuronal activity and behavior. Annu Rev Physiol 2010;72:335-55.