메뉴 건너뛰기




Volumn 29, Issue 9, 2011, Pages 1437-1442

Effects of interleukin-6 ablation on fracture healing in mice

Author keywords

cytokines; fracture healing; interleukin 6

Indexed keywords

ALKALINE PHOSPHATASE; INTERLEUKIN 6; OSTEOCALCIN; TARTARIC ACID DERIVATIVE; TARTRATE RESISTANT ALKALINE PHOSPHATASE; UNCLASSIFIED DRUG;

EID: 79960233326     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21367     Document Type: Article
Times cited : (66)

References (40)
  • 2
    • 0026331752 scopus 로고
    • The occurrence of accessory immunologic cells in bone induction
    • Henricson A, Hulth A, Johnell O,. 1991. The occurrence of accessory immunologic cells in bone induction. Clin Orthop 260: 270-277.
    • (1991) Clin Orthop , vol.260 , pp. 270-277
    • Henricson, A.1    Hulth, A.2    Johnell, O.3
  • 4
    • 33845439865 scopus 로고    scopus 로고
    • Roles of neutrophil-mediated inflammatory response in the bony repair of injured growth plate cartilage in young rats
    • DOI 10.1189/jlb.0606365
    • Chung R, Cool JC, Scherer MA, et al. 2006. Roles of neutrophil-mediated inflammatory response in bony repair of injured growth plate cartilage in young rats. J Leukocyte Biol 80: 1272-1280. (Pubitemid 44904966)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.6 , pp. 1272-1280
    • Chung, R.1    Cool, J.C.2    Scherer, M.A.3    Foster, B.K.4    Xian, C.J.5
  • 5
    • 0029102852 scopus 로고
    • The expression of cytokine activity by fracture callus
    • Einhorn TA, Majeska RJ, Rush EB, et al. 1995. The expression of cytokine activity by fracture callus. J Bone Miner Res 10: 1272-1281.
    • (1995) J Bone Miner Res , vol.10 , pp. 1272-1281
    • Einhorn, T.A.1    Majeska, R.J.2    Rush, E.B.3
  • 9
    • 0027480288 scopus 로고
    • Proliferative responses to estradiol, IL-1α and TGFβ by cells expressing alkaline phosphatase in human osteoblast-like cell cultures
    • Rickard DJ, Gowen M, MacDonald BR,. 1993. Proliferative responses to estradiol, IL-1 alpha and TGF beta by cells expressing alkaline phosphatase in human osteoblast-like cell cultures. Calcif Tissue Int 52: 227-233. (Pubitemid 23090717)
    • (1993) Calcified Tissue International , vol.52 , Issue.3 , pp. 227-233
    • Rickard, D.J.1    Gowen, M.2    MacDonald, B.R.3
  • 10
    • 0033145956 scopus 로고    scopus 로고
    • Regulation of osteoblast levels during bone healing
    • Olmedo ML, Landry PS, Sadasivan KK, et al. 1999. Regulation of osteoblast levels during bone healing. J Orthop Trauma 13: 356-362.
    • (1999) J Orthop Trauma , vol.13 , pp. 356-362
    • Olmedo, M.L.1    Landry, P.S.2    Sadasivan, K.K.3
  • 11
    • 0034133883 scopus 로고    scopus 로고
    • Programmed cell death in post-traumatic bone callus
    • Olmedo ML, Landry PS, Sadasivan KK, et al. 2000. Programmed cell death in post-traumatic bone callus. Cell Mol Biol 46: 89-97.
    • (2000) Cell Mol Biol , vol.46 , pp. 89-97
    • Olmedo, M.L.1    Landry, P.S.2    Sadasivan, K.K.3
  • 12
    • 0026357819 scopus 로고
    • Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: Regulation by interleukin
    • Linkhart TA, Linkhart SG, MacCharles DC, et al. 1991. Interleukin-6 messenger RNA expression and interleukin-6 protein secretion in cells isolated from normal human bone: regulation by interleukin. J Bone Miner Res 6: 1285-1294.
    • (1991) J Bone Miner Res , vol.6 , pp. 1285-1294
    • Linkhart, T.A.1    Linkhart, S.G.2    MacCharles, D.C.3
  • 14
    • 0034114307 scopus 로고    scopus 로고
    • Unbiased determination of cytokine localization in bone: Colocalization of interleukin-6 with osteoblasts in serial sections from monkey vertebrae
    • DOI 10.1016/S8756-3282(00)00244-1, PII S8756328200002441
    • Johnson CS, Jerome CP, Brommage R,. 2000. Unbiased determination of cytokine localization in bone: colocalization of interleukin-6 with osteoblasts in serial sections from monkey vertebrae. Bone 26: 461-467. (Pubitemid 30204466)
    • (2000) Bone , vol.26 , Issue.5 , pp. 461-467
    • Johnson, C.S.1    Jerome, C.P.2    Brommage, R.3
  • 15
  • 16
    • 33746599062 scopus 로고    scopus 로고
    • A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation
    • DOI 10.1016/j.bone.2006.02.074, PII S8756328206003516
    • Itoh S, Udagawa N, Takahashi N, et al. 2006. A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation. Bone 39: 505-512. (Pubitemid 44149269)
    • (2006) Bone , vol.39 , Issue.3 , pp. 505-512
    • Itoh, S.1    Udagawa, N.2    Takahashi, N.3    Yoshitake, F.4    Narita, H.5    Ebisu, S.6    Ishihara, K.7
  • 17
    • 48149110985 scopus 로고    scopus 로고
    • IL-6 receptor expression and IL-6 effects change during osteoblast differentiation
    • Li Y, Backesjo CM, Haldosen LA, et al. 2008. IL-6 receptor expression and IL-6 effects change during osteoblast differentiation. Cytokine 43: 165-173.
    • (2008) Cytokine , vol.43 , pp. 165-173
    • Li, Y.1    Backesjo, C.M.2    Haldosen, L.A.3
  • 18
    • 0030857451 scopus 로고    scopus 로고
    • Activation of the Janus kinase/STAT (signal transducer and activator of transcription) signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation
    • DOI 10.1210/en.138.9.3666
    • Bellido T, Borba VZC, Roberson P, et al. 1997. Activation of the Janus Kinase/STAT (signal transducer and activator of transcription) signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation. Endocrinol 138: 3666-3676. (Pubitemid 27351915)
    • (1997) Endocrinology , vol.138 , Issue.9 , pp. 3666-3676
    • Bellido, T.1    Borba, V.Z.C.2    Roberson, P.3    Manolagas, S.C.4
  • 19
    • 0027241733 scopus 로고
    • Interleukin-6 inhibits bone formation in vitro
    • Hughes FJ, Howells GL,. 1993. Interleukin-6 inhibits bone formation in vitro. Bone Miner 21: 21-28. (Pubitemid 23161155)
    • (1993) Bone and Mineral , vol.21 , Issue.1 , pp. 21-28
    • Hughes, F.J.1    Howells, G.L.2
  • 20
    • 34548590952 scopus 로고    scopus 로고
    • Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts
    • Chae HJ, Ha KC, Lee GY, et al. 2007. Interleukin-6 and cyclic AMP stimulate release of cathepsin B in human osteoblasts. Immunopharmacol Immunotoxicol 29: 155-172.
    • (2007) Immunopharmacol Immunotoxicol , vol.29 , pp. 155-172
    • Chae, H.J.1    Ha, K.C.2    Lee, G.Y.3
  • 22
    • 27444435586 scopus 로고    scopus 로고
    • Patterns and localization of gene expression during intramembranous bone regeneration in the rat femoral marrow ablation model
    • Kuroda S, Virdi AS, Dai Y, et al. 2005. Patterns and localization of gene expression during intramembranous bone regeneration in the rat femoral marrow ablation model. Calcif Tissue Int 77: 212-215.
    • (2005) Calcif Tissue Int , vol.77 , pp. 212-215
    • Kuroda, S.1    Virdi, A.S.2    Dai, Y.3
  • 23
    • 0037376627 scopus 로고    scopus 로고
    • Fracture healing as a post-natal developmental process: Molecular, spatial, and temporal aspects of its regulation
    • DOI 10.1002/jcb.10435
    • Gerstenfeld LC, Culliane DM, Barnes GL, et al. 2003. Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 88: 873-884. (Pubitemid 36337032)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.5 , pp. 873-884
    • Gerstenfeld, L.C.1    Cullinane, D.M.2    Barnes, G.L.3    Graves, D.T.4    Einhorn, T.A.5
  • 24
    • 36148989585 scopus 로고    scopus 로고
    • Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice
    • DOI 10.1016/j.bone.2007.07.022, PII S8756328207005546
    • Yang X, Ricciardi BF, Hernandez-Soria A, et al. 2007. Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice. Bone 41: 928-936. (Pubitemid 350116738)
    • (2007) Bone , vol.41 , Issue.6 , pp. 928-936
    • Yang, X.1    Ricciardi, B.F.2    Hernandez-Soria, A.3    Shi, Y.4    Pleshko Camacho, N.5    Bostrom, M.P.G.6
  • 25
    • 69449090213 scopus 로고    scopus 로고
    • Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo
    • Axmann R, Bohm C, Kronke G, et al. 2009. Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo. Arthritis Rheum 60: 2747-2756.
    • (2009) Arthritis Rheum , vol.60 , pp. 2747-2756
    • Axmann, R.1    Bohm, C.2    Kronke, G.3
  • 28
    • 0036259278 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair
    • DOI 10.1172/JCI200215681
    • Zhang X, Schwarz EM, Young DA, et al. 2002. Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest 109: 1405-1415. (Pubitemid 34596166)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.11 , pp. 1405-1415
    • Zhang, X.1    Schwarz, E.M.2    Young, D.A.3    Edward Puzas, J.4    Rosier, R.N.5    O'Keefe, R.J.6
  • 29
    • 33644847701 scopus 로고    scopus 로고
    • A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats
    • DOI 10.1097/01.bot.0000184144.98071.5d, PII 0000513120051100000007
    • Bergenstock M, Min W, Simon AM, et al. 2005. A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats. J Orthop Trauma 19: 717-723. (Pubitemid 44378210)
    • (2005) Journal of Orthopaedic Trauma , vol.19 , Issue.10 , pp. 717-723
    • Bergenstock, M.1    Min, W.2    Simon, A.M.3    Sabatino, C.4    O'Connor, J.P.5
  • 30
    • 33746875639 scopus 로고    scopus 로고
    • Parecoxib impairs early metaphyseal bone healing in rats
    • DOI 10.1007/s00402-006-0160-3
    • Meunier A, Aspenberg P,. 2006. Parecoxib impairs early metaphyseal bone healing in rats. Arch Orthop Trauma Surg 126: 433-436. (Pubitemid 44194505)
    • (2006) Archives of Orthopaedic and Trauma Surgery , vol.126 , Issue.7 , pp. 433-436
    • Meunier, A.1    Aspenberg, P.2
  • 31
    • 33947116489 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition delays the attainment of peak woven bone formation following four-point bending in the rat
    • DOI 10.1007/s00223-006-0170-8
    • Gregory LS, Forwood MR,. 2007. Cyclooxygenase-2 inhibition delays the attainment of peak woven bone formation following four-point bending in the rat. Calcif Tissue Int 80: 176-183. (Pubitemid 46411879)
    • (2007) Calcified Tissue International , vol.80 , Issue.3 , pp. 176-183
    • Gregory, L.S.1    Forwood, M.R.2
  • 32
    • 58149389983 scopus 로고    scopus 로고
    • Effects of a cyclooxygenase 2 inhibitor on fracture healing in a rat model
    • Herbenick MA, Sprott D, Stills H, et al. 2008. Effects of a cyclooxygenase 2 inhibitor on fracture healing in a rat model. Am J Orthop 37: E133-E137.
    • (2008) Am J Orthop , vol.37
    • Herbenick, M.A.1    Sprott, D.2    Stills, H.3
  • 33
    • 0026155524 scopus 로고
    • The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters
    • Huo MH, Troiano NW, Pelker RR, et al. 1991. The influence of ibuprofen on fracture repair: biomechanical, biochemical, histologic, and histomorphometric parameters. J Orthop Res 9: 383-390.
    • (1991) J Orthop Res , vol.9 , pp. 383-390
    • Huo, M.H.1    Troiano, N.W.2    Pelker, R.R.3
  • 34
    • 46349111508 scopus 로고    scopus 로고
    • Interleukin-6 inhibits receptor activator of nuclear factor κβ ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: Key role of Serine 727 phosphorylation of signal transducer and activator of transcription 3
    • Duplomb L, Baud'huin M, Charrier C, et al. 2008. Interleukin-6 inhibits receptor activator of nuclear factor κβ ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine 727 phosphorylation of signal transducer and activator of transcription 3. Endocrinol 149: 688-697.
    • (2008) Endocrinol , vol.149 , pp. 688-697
    • Duplomb, L.1    Baud'Huin, M.2    Charrier, C.3
  • 35
    • 45549097409 scopus 로고    scopus 로고
    • Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-κβ signaling pathways
    • Yoshatake F, Itoh S, Narita H, et al. 2008. Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-κβ signaling pathways. J Biol Chem 283: 11535-11540.
    • (2008) J Biol Chem , vol.283 , pp. 11535-11540
    • Yoshatake, F.1    Itoh, S.2    Narita, H.3
  • 36
    • 67649877902 scopus 로고    scopus 로고
    • Osteocalcin secretion as an early marker of in vitro osteogenic differentiation of rat mesenchymal stem cells
    • Nakamura A, Dohi Y, Akahane M, et al. 2009. Osteocalcin secretion as an early marker of in vitro osteogenic differentiation of rat mesenchymal stem cells. Tissue Eng Part C Methods 15: 169-180.
    • (2009) Tissue Eng Part C Methods , vol.15 , pp. 169-180
    • Nakamura, A.1    Dohi, Y.2    Akahane, M.3
  • 37
    • 0026085747 scopus 로고
    • Human osteoblast like cells do not respond to interleukin-6
    • Littlewood AJ, Aarden LA, Evans DB, et al. 1991. Human osteoblast like cells do not respond to interleukin-6. J Bone Miner Res 6: 141-148.
    • (1991) J Bone Miner Res , vol.6 , pp. 141-148
    • Littlewood, A.J.1    Aarden, L.A.2    Evans, D.B.3
  • 38
    • 0031966146 scopus 로고    scopus 로고
    • Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells
    • DOI 10.1359/jbmr.1998.13.5.777
    • Nishimura R, Moriyama K, Yasukawa K, et al. 1998. Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblast cells. J Bone Miner Res 13: 777-785. (Pubitemid 28224193)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.5 , pp. 777-785
    • Nishimura, R.1    Moriyama, K.2    Yasukawa, K.3    Mundy, G.R.4    Yoneda, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.