-
4
-
-
0028810979
-
Insulin activates nuclear factor kappa B in mammalian cells through a Raf-1-mediated pathway
-
7592658 10.1074/jbc.270.41.24435 1:CAS:528:DyaK2MXovVSnsrw%3D
-
F. Bertrand C. Philippe P. J. Antoine L. Baud A. Groyer J. Capeau G. Cherqui 1995 Insulin activates nuclear factor kappa B in mammalian cells through a Raf-1-mediated pathway J. Biol. Chem. 270 24435 24441 7592658 10.1074/jbc.270.41.24435 1:CAS:528:DyaK2MXovVSnsrw%3D
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24435-24441
-
-
Bertrand, F.1
Philippe, C.2
Antoine, P.J.3
Baud, L.4
Groyer, A.5
Capeau, J.6
Cherqui, G.7
-
5
-
-
1242296255
-
Graves' IgG activate upstream enhancer of the sodium/iodide symporter
-
DOI 10.1016/j.mce.2003.10.039
-
E. Breous A. Wenzel U. Loos 2003 Graves' IgG activate upstream enhancer of the sodium/iodide symporter Mol. Cell. Endocrinol. 213 109 113 15062579 10.1016/j.mce.2003.10.039 1:CAS:528:DC%2BD2cXhsV2rtL4%3D (Pubitemid 38229160)
-
(2003)
Molecular and Cellular Endocrinology
, vol.213
, Issue.1
, pp. 109-113
-
-
Breous, E.1
Wenzel, A.2
Loos, U.3
-
6
-
-
59649089769
-
Effect of type i interferon(s) on cell viability and apoptosis in primary human thyrocyte cultures
-
19191746 10.1089/thy.2008.0290 1:CAS:528:DC%2BD1MXhsFWnsb0%3D
-
N. Caraccio S. Cuccato F. Pratesi A. Dardano S. Ursino D. Chimenti L. Boldrini G. Materazzi P. Migliorini F. Monzani 2009 Effect of type I interferon(s) on cell viability and apoptosis in primary human thyrocyte cultures Thyroid 19 149 155 19191746 10.1089/thy.2008.0290 1:CAS:528: DC%2BD1MXhsFWnsb0%3D
-
(2009)
Thyroid
, vol.19
, pp. 149-155
-
-
Caraccio, N.1
Cuccato, S.2
Pratesi, F.3
Dardano, A.4
Ursino, S.5
Chimenti, D.6
Boldrini, L.7
Materazzi, G.8
Migliorini, P.9
Monzani, F.10
-
7
-
-
36849074161
-
Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation
-
DOI 10.1016/j.febslet.2007.11.021, PII S0014579307011659
-
C. T. Chiang T. D. Way S. J. Tsai J. K. Lin 2007 Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation FEBS Lett. 581 5735 5742 18022396 10.1016/j.febslet.2007.11.021 1:CAS:528:DC%2BD2sXhsVChu7bP (Pubitemid 350235422)
-
(2007)
FEBS Letters
, vol.581
, Issue.30
, pp. 5735-5742
-
-
Chiang, C.-T.1
Way, T.-D.2
Tsai, S.-J.3
Lin, J.-K.4
-
8
-
-
0642348024
-
Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells
-
12632085 1:CAS:528:DC%2BD3sXislWhtr8%3D
-
C. Corbiere B. Liagre A. Bianchi K. Bordji M. Dauça P. Netter J. L. Beneytout 2003 Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells Int. J. Oncol. 22 899 905 12632085 1:CAS:528: DC%2BD3sXislWhtr8%3D
-
(2003)
Int. J. Oncol.
, vol.22
, pp. 899-905
-
-
Corbiere, C.1
Liagre, B.2
Bianchi, A.3
Bordji, K.4
Dauça, M.5
Netter, P.6
Beneytout, J.L.7
-
10
-
-
5144233086
-
Final report of the amended safety assessment of Dioscorea Villosa (Wild Yam) root extract
-
H. Eric 2004 Final report of the amended safety assessment of Dioscorea Villosa (Wild Yam) root extract Int. J. Toxicol. 23 Suppl2 49 54
-
(2004)
Int. J. Toxicol.
, vol.23
, Issue.SUPPL. 2
, pp. 49-54
-
-
Eric, H.1
-
11
-
-
0033515604
-
Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor B
-
DOI 10.1074/jbc.274.14.9828
-
S. Heck F. Lezoualc'h S. Engert C. Behl 1999 Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor kappaB J. Biol. Chem. 274 9828 9835 10092673 10.1074/jbc.274.14.9828 1:CAS:528:DyaK1MXisVWks7w%3D (Pubitemid 29180306)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.14
, pp. 9828-9835
-
-
Heck, S.1
Lezoualc'h, F.2
Engert, S.3
Behl, C.4
-
12
-
-
0027967944
-
Rules to replicate by
-
DOI 10.1016/0092-8674(94)90541-X
-
K. A. Heichman J. M. Roberts 1994 Rules to replicate by Cell 79 557 562 7954822 10.1016/0092-8674(94)90541-X 1:CAS:528:DyaK2MXit1Glu7s%3D (Pubitemid 24363799)
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 557-562
-
-
Heichman, K.A.1
Roberts, J.M.2
-
14
-
-
33644778091
-
IGF-1 increases laminin, cyclin D1, and P21Cip1 expression in glomerular mesangial cells: An investigation of the intracellular signaling pathway and cell-cycle progression
-
16408277 10.1002/jcb.20771 1:CAS:528:DC%2BD28XjslaqsL8%3D
-
Y. Jiang D. W. Cheng E. Levi L. P. Singh 2006 IGF-1 increases laminin, cyclin D1, and P21Cip1 expression in glomerular mesangial cells: an investigation of the intracellular signaling pathway and cell-cycle progression J. Cell. Biochem. 98 208 220 16408277 10.1002/jcb.20771 1:CAS:528: DC%2BD28XjslaqsL8%3D
-
(2006)
J. Cell. Biochem.
, vol.98
, pp. 208-220
-
-
Jiang, Y.1
Cheng, D.W.2
Levi, E.3
Singh, L.P.4
-
15
-
-
0023258442
-
In vivo and in vitro studies of hypocholesterolemic effects of diosgenin in rats
-
DOI 10.1016/0020-711X(87)90080-2
-
M. A. Juarez-Oropeza J. C. Diaz-Zagoya J. L. Rabinowitz 1987 In vivo and in vitro studies of hypocholesterolemic effects of diosgenin in rats Int. J. Biochem. 19 679 683 3622900 10.1016/0020-711X(87)90080-2 1:CAS:528: DyaL2sXlvFSktr8%3D (Pubitemid 17132084)
-
(1987)
International Journal of Biochemistry
, vol.19
, Issue.8
, pp. 679-683
-
-
Juarez-Oropeza, M.A.1
Diaz-Zagoya, J.C.2
Rabinowitz, J.L.3
-
16
-
-
0034793849
-
Regulation of thyroid cell proliferation by tsh and other factors: A critical evaluation of in vitro models
-
DOI 10.1210/er.22.5.631
-
T. Kimura A. Van Keymeulen J. Golstein A. Fusco J. E. Dumont P. P. Roger 2001 Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models Endocr. Rev. 22 631 656 11588145 10.1210/er.22.5.631 1:CAS:528:DC%2BD3MXotVWmu7g%3D (Pubitemid 32955247)
-
(2001)
Endocrine Reviews
, vol.22
, Issue.5
, pp. 631-656
-
-
Kimura, T.1
Van Keymeulen, A.2
Golstein, J.3
Fusco, A.4
Dumont, J.E.5
Roger, P.P.6
-
17
-
-
10444259877
-
Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration
-
DOI 10.1634/stemcells.2004-0127
-
T. Kofidis J. L. de Bruin T. Yamane L. B. Balsam D. R. Lebl R. J. Swijnenburg M. Tanaka I. L. Weissman R. C. Robbins 2004 Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration Stem Cells 22 1239 1245 15579642 10.1634/stemcells.2004-0127 1:CAS:528:DC%2BD2MXks1ehsQ%3D%3D (Pubitemid 39636401)
-
(2004)
Stem Cells
, vol.22
, Issue.7
, pp. 1239-1245
-
-
Kofidis, T.1
De Bruin, J.L.2
Yamane, T.3
Balsam, L.B.4
Lebl, D.R.5
Swijnenburg, R.-J.6
Tanaka, M.7
Weissman, I.L.8
Robbins, R.C.9
-
18
-
-
2442610654
-
Anti-obesity effect of Dioscorea nipponica makino with lipase-inhibitory activity in rodents
-
C. S. Kwon H. Y. Sohn S. H. Kim J. H. Kim K. H. Son J. S. Lee J. K. Lim J. S. Kim 2003 Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents Biosci. Biotechnol. Biochem. 67 1451 1456 12913286 10.1271/bbb.67.1451 1:CAS:528:DC%2BD3sXmtFelurg%3D (Pubitemid 39251780)
-
(2003)
Bioscience, Biotechnology and Biochemistry
, vol.67
, Issue.7
, pp. 1451-1456
-
-
Kwon, C.-S.1
Sohn, H.Y.2
Kim, S.H.3
Kim, J.H.4
Son, K.H.5
Lee, J.S.6
Lim, J.K.7
Kim, J.-S.8
-
19
-
-
24644498545
-
Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, Dioscorea polygonoides
-
DOI 10.1016/j.fct.2005.05.008, PII S0278691505001535
-
M. A. McAnuff W. W. Harding F. O. Omoruyi H. Jacobs E. Y. Morrison H. N. Asemota 2005 Hypoglycemic effects of steroidal sapogenins isolated from Jamaican bitter yam, Dioscorea polygonoides Food Chem. Toxicol. 43 1667 1672 16000232 10.1016/j.fct.2005.05.008 1:CAS:528:DC%2BD2MXpvFemurk%3D (Pubitemid 41265897)
-
(2005)
Food and Chemical Toxicology
, vol.43
, Issue.11
, pp. 1667-1672
-
-
McAnuff, M.A.1
Harding, W.W.2
Omoruyi, F.O.3
Jacobs, H.4
Morrison, E.Y.5
Asemota, H.N.6
-
20
-
-
0037295455
-
Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues
-
DOI 10.1507/endocrj.50.77
-
M. Miyakawa T. Tsushima H. Murakami K. Wakai O. Isozaki K. Takano 2003 Increased expression of phosphorylated p70S6 kinase and Akt in papillary thyroid cancer tissues Endocr. J. 50 77 83 12733712 10.1507/endocrj.50.77 1:CAS:528:DC%2BD3sXjtFelsLg%3D (Pubitemid 36305850)
-
(2003)
Endocrine Journal
, vol.50
, Issue.1
, pp. 77-83
-
-
Miyakawa, M.1
Tsushima, T.2
Murakami, H.3
Wakai, K.4
Isozaki, O.5
Takano, K.6
-
21
-
-
14844364704
-
Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways
-
DOI 10.1161/01.RES.0000157671.47477.71
-
K. Radcliff T. B. Tang J. Lim Z. Zhang M. Abedin L. L. Demer Y. Tintut 2005 Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathways Circ. Res. 96 398 400 15692088 10.1161/01.RES.0000157671.47477.71 1:CAS:528:DC%2BD2MXhs12isLg%3D (Pubitemid 40354532)
-
(2005)
Circulation Research
, vol.96
, Issue.4
, pp. 398-400
-
-
Radcliff, K.1
Tang, T.-B.2
Lim, J.3
Zhang, Z.4
Abedin, M.5
Demer, L.L.6
Tintut, Y.7
-
22
-
-
4043124898
-
Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells
-
J. Raju J. M. Patlolla M. V. Swamy C. V. Rao 2004 Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells Cancer Epidemiol. Biomarkers Prev. 13 1392 1398 15298963 1:CAS:528:DC%2BD2cXmtleks7w%3D (Pubitemid 39071566)
-
(2004)
Cancer Epidemiology Biomarkers and Prevention
, vol.13
, Issue.8
, pp. 1392-1398
-
-
Raju, J.1
Patlolla, J.M.R.2
Swamy, M.V.3
Rao, C.V.4
-
23
-
-
64849094780
-
Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells
-
19060913 10.1038/aps.2008.8 1:CAS:528:DC%2BD1MXitlemuw%3D%3D
-
M. Ren X. Zhong C. Y. Ma Y. Sun Q. B. Guan B. Cui J. Guo H. Wang L. Gao J. J. Zhao 2009 Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells Acta Pharmacol. Sin. 30 113 119 19060913 10.1038/aps.2008.8 1:CAS:528: DC%2BD1MXitlemuw%3D%3D
-
(2009)
Acta Pharmacol. Sin.
, vol.30
, pp. 113-119
-
-
Ren, M.1
Zhong, X.2
Ma, C.Y.3
Sun, Y.4
Guan, Q.B.5
Cui, B.6
Guo, J.7
Wang, H.8
Gao, L.9
Zhao, J.J.10
-
24
-
-
0035011548
-
Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling
-
J. Saito A. D. Kohn R. A. Roth Y. Noguchi I. Tatsumo A. Hirai K. Suzuki L. D. Kohn M. Saji M. D. Ringel 2001 Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling Thyroid 11 339 351 11349832 10.1089/10507250152039073 1:CAS:528:DC%2BD3MXlt1Gnurk%3D (Pubitemid 32422626)
-
(2001)
Thyroid
, vol.11
, Issue.4
, pp. 339-351
-
-
Saito, J.1
Kohn, A.D.2
Roth, R.A.3
Noguchi, Y.4
Tatsumo, I.5
Hirai, A.6
Suuki, K.7
Kohn, L.D.8
Saji, M.9
Ringel, M.D.10
-
25
-
-
33644840279
-
Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, IkappaB kinase activation and NF-kappaB-regulated gene expression
-
DOI 10.1038/sj.onc.1209194, PII 1209194
-
S. Shishodia B. B. Aggarwal 2006 Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression Oncogene 25 1463 1473 16331273 10.1038/sj.onc.1209194 1:CAS:528:DC%2BD28XitFGht78%3D (Pubitemid 43361932)
-
(2006)
Oncogene
, vol.25
, Issue.10
, pp. 1463-1473
-
-
Shishodia, S.1
Aggarwal, B.B.2
-
26
-
-
37649008319
-
Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats
-
18071250 10.1271/bbb.70472 1:CAS:528:DC%2BD1cXktVGqtQ%3D%3D
-
I. S. Son J. H. Kim H. Y. Sohn K. H. Son J. S. Kim C. S. Kwon 2007 Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats Biosci. Biotechnol. Biochem. 71 3063 3071 18071250 10.1271/bbb.70472 1:CAS:528:DC%2BD1cXktVGqtQ%3D%3D
-
(2007)
Biosci. Biotechnol. Biochem.
, vol.71
, pp. 3063-3071
-
-
Son, I.S.1
Kim, J.H.2
Sohn, H.Y.3
Son, K.H.4
Kim, J.S.5
Kwon, C.S.6
-
27
-
-
62149097572
-
Novel effects of diosgenin on skin aging
-
10.1016/j.steroids.2009.01.006 1:CAS:528:DC%2BD1MXjsFajtbg%3D
-
Y. Tada N. Kanda A. Haratake M. Tobiishi H. Uchiwa S. Watanabe 2009 Novel effects of diosgenin on skin aging Steroid 74 504 511 10.1016/j.steroids.2009. 01.006 1:CAS:528:DC%2BD1MXjsFajtbg%3D
-
(2009)
Steroid
, vol.74
, pp. 504-511
-
-
Tada, Y.1
Kanda, N.2
Haratake, A.3
Tobiishi, M.4
Uchiwa, H.5
Watanabe, S.6
-
28
-
-
0033667416
-
Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds
-
11087460 10.1021/jf000467t 1:CAS:528:DC%2BD3cXntVehu7w%3D
-
W. G. Taylor J. L. Elder P. R. Chang K. W. Richards 2000 Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds J. Agric. Food Chem. 48 5206 5210 11087460 10.1021/jf000467t 1:CAS:528:DC%2BD3cXntVehu7w%3D
-
(2000)
J. Agric. Food Chem.
, vol.48
, pp. 5206-5210
-
-
Taylor, W.G.1
Elder, J.L.2
Chang, P.R.3
Richards, K.W.4
-
29
-
-
33745248696
-
Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: Protection by diosgenin and l-deprenyl
-
DOI 10.1016/j.nbd.2006.02.005, PII S0969996106000374
-
J. Turchan-Cholewo Y. Liu S. Gartner R. Reid C. Jie X. Peng K. C. Chen A. Chauhan N. Haughey R. Cutler M. P. Mattson C. Pardo K. Conant N. Sacktor J. C. McArthur K. F. Hauser C. Gairola A. Nath 2006 Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl Neurobiol. Dis. 23 109 119 16697650 10.1016/j.nbd.2006.02.005 1:CAS:528:DC%2BD28XlvFyqsLY%3D (Pubitemid 43922460)
-
(2006)
Neurobiology of Disease
, vol.23
, Issue.1
, pp. 109-119
-
-
Turchan-Cholewo, J.1
Liu, Y.2
Gartner, S.3
Reid, R.4
Jie, C.5
Peng, X.6
Chen, K.C.C.7
Chauhan, A.8
Haughey, N.9
Cutler, R.10
Mattson, M.P.11
Pardo, C.12
Conant, K.13
Sacktor, N.14
McArthur, J.C.15
Hauser, K.F.16
Gairola, C.17
Nath, A.18
-
30
-
-
0031159353
-
Cyclin D1 is required for S phase traversal in bovine tracheal myocytes
-
9227524 1:CAS:528:DyaK2sXktlKmsr4%3D
-
W. Xiong R. G. Pestell G. Watanabe J. Li M. R. Rosner M. B. Hershenson 1997 Cyclin D1 is required for S phase traversal in bovine tracheal myocytes Am. J. Physiol. 272 6Pt1 L1205 L1210 9227524 1:CAS:528:DyaK2sXktlKmsr4%3D
-
(1997)
Am. J. Physiol.
, vol.272
, Issue.6 PART 1
-
-
Xiong, W.1
Pestell, R.G.2
Watanabe, G.3
Li, J.4
Rosner, M.R.5
Hershenson, M.B.6
|