Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kB signaling pathway in FRTL thyroid cells

Acta Pharmacologica Sinica

Volumn 30, Issue 1, 2009, Pages 113-119

  Ren, Meng ^a,c   Zhong, Xia ^a   Ma, Chun Yan ^a   Sun, Ying ^b   Guan, Qing Bo ^a   Cui, Bin ^a   Guo, Jun ^a   Wang, Hai ^a   Gao, Ling ^a   Zhao, Jia Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b YANTAI YUHUANGDING HOSPITAL   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cyclin D1; Insulin like growth factor 1; Nuclear factor kB; Phosphatidylinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; CYCLIN D1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN C; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; NITRILE; SULFONE;

ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; THYROID CELL; ANIMAL; CELL CYCLE; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PHYSIOLOGY; RAT; THYROID GLAND;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL CYCLE; CELL LINE; CHROMONES; CYCLIN D1; INSULIN-LIKE GROWTH FACTOR I; MORPHOLINES; NF-KAPPA B; NITRILES; RATS; SIGNAL TRANSDUCTION; SULFONES; THYROID GLAND;

EID: 64849094780     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2008.8     Document Type: Article

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