Structural basis for retinoic X receptor repression on the tetramer

Journal of Biological Chemistry

Volumn 286, Issue 28, 2011, Pages 24593-24598

  Zhang, Haitao ^a   Chen, Lili ^a   Chen, Jing ^a   Jiang, Hualiang ^a   Shen, Xu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION FUNCTIONS; CELL DEVELOPMENT; COACTIVATORS; COREPRESSORS; LIGAND BINDING DOMAIN; MOLECULAR DETERMINANTS; MOLECULAR MECHANISM; MOLECULAR MODELS; NUCLEAR RECEPTORS; STRUCTURAL BASIS; STRUCTURAL REARRANGEMENT; STRUCTURAL SUPERPOSITIONS; TETRAMERS; THYROID HORMONE RECEPTOR;

CRYSTAL STRUCTURE; EMPLOYMENT; PEPTIDES;

OLIGOMERS;

RETINOID X RECEPTOR; RHEIN; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STEROID RECEPTOR COACTIVATOR 1; TETRAMER;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; ENZYME REPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR DYNAMICS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID MOTIFS; ANTHRAQUINONES; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RETINOID X RECEPTOR ALPHA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79960121686     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.245498     Document Type: Article

References (24)

1. McKenna, N. J., and O'Malley, B. W. (2010) Cell 142, 822-822.e1
2. Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., and Gronemeyer, H. (2006) Pharmacol. Rev. 58, 760-772
3. Egea, P. F., Mitschler, A., Rochel, N., Ruff, M., Chambon, P., and Moras, D. (2000) EMBO J. 19, 2592-2601
4. Gampe, R. T., Jr., Montana, V. G., Lambert, M. H., Wisely, G. B., Milburn, M. V., and Xu, H. E. (2000) Genes Dev. 14, 2229-2241
5. Zhang, H., Zhou, R., Li, L., Chen, J., Chen, L., Li, C., Ding, H., Yu, L., Hu, L., Jiang, H., and Shen, X. (2011) J. Biol. Chem. 286, 1868-1875
6. Safer, J. D., Cohen, R. N., Hollenberg, A. N., and Wondisford, F. E. (1998) J. Biol. Chem. 273, 30175-30182
7. Yoh, S. M., Chatterjee, V. K., and Privalsky, M. L. (1997) Mol. Endocrinol. 11, 470-480
8. Karagianni, P., and Wong, J. (2007) Oncogene 26, 5439-5449
9. Fernández-Majada, V., Pujadas, J., Vilardell, F., Capella, G., Mayo, M. W., Bigas, A., and Espinosa, L. (2007) Cell Cycle 6, 1748-1752
10. Uchikawa, J., Shiozawa, T., Shih, H. C., Miyamoto, T., Feng, Y. Z., Kashima, H., Oka, K., and Konishi, I. (2003) Cancer 98, 2207-2213
11. Fang, S., Suh, J. M., Atkins, A. R., Hong, S. H., Leblanc, M., Nofsinger, R. R., Yu, R. T., Downes, M., and Evans, R. M. (2011) Proc. Natl. Acad. Sci. U.S.A. 108, 3412-3417
12. Xu, H. E., Stanley, T. B., Montana, V. G., Lambert, M. H., Shearer, B. G., Cobb, J. E., McKee, D. D., Galardi, C. M., Plunket, K. D., Nolte, R. T., Parks, D. J., Moore, J. T., Kliewer, S. A., Willson, T. M., and Stimmel, J. B. (2002) Nature 415, 813-817
13. Wang, L., Zuercher, W. J., Consler, T. G., Lambert, M. H., Miller, A. B., Orband-Miller, L. A., McKee, D. D., Willson, T. M., and Nolte, R. T. (2006) J. Biol. Chem. 281, 37773-37781
14. He, Z. H., He, M. F., Ma, S. C., and But, P. P. (2009) J. Ethnopharmacol. 121, 313-317
15. Jia, Z. H., Liu, Z. H., Zheng, J. M., Zeng, C. H., and Li, L. S. (2007) Exp. Clin. Endocrinol. Diabetes 115, 571-576
16. Gao, Q., Qin, W. S., Jia, Z. H., Zheng, J. M., Zeng, C. H., Li, L. S., and Liu, Z. H. (2010) Planta Med. 76, 27-33
17. Otwinowski, Z., and Minor, W. (1997) Methods Enzymo. 276, 307-326
18. Collaborative Computational Project Number 4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
19. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
20. Zhang, H., Li, L., Chen, L., Hu, L., Jiang, H., and Shen, X. (2011) J. Mol. Biol. 407, 13-20
21. Ghosh, J. C., Yang, X., Zhang, A., Lambert, M. H., Li, H., Xu, H. E., and Chen, J. D. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 5842-5847
22. Zhang, J., Hu, X., and Lazar, M. A. (1999) Mol. Cell. Biol. 19, 6448-6457
23. Renaud, J. P., and Moras, D. (2000) Cell. Mol. Life Sci. 57, 1748-1769
24. Hu, X., Li, Y., and Lazar, M. A. (2001) Mol. Cell. Biol. 21, 1747-1758