메뉴 건너뛰기




Volumn 82, Issue 6, 2011, Pages 811-817

Anticoagulant effect of polyphenols-rich extracts from black chokeberry and grape seeds

Author keywords

Chokeberry; Coagulation; Grape seeds; Polyphenols; Thrombin

Indexed keywords

10 NEOCHLOROGENIC ACID; 11 CHLOROGENIC ACID; 3 PROCYANIDIN B1; 4 PROCYANIDIN B2; 7 CYANIDIN 3 GLUCOSIDE; 8 CYANIDIN 3 ARABINOSIDE; 9 CYANIDIN 3 XYLOSIDE; ANTICOAGULANT AGENT; CATECHIN; CYANIDIN 3 GALACTOSIDE; ENZYME PRECURSOR; EPICATECHIN; POLYPHENOL DERIVATIVE; PROCYANIDIN C1; THROMBIN; UNCLASSIFIED DRUG;

EID: 79960091760     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2011.04.017     Document Type: Article
Times cited : (72)

References (75)
  • 1
    • 37049044629 scopus 로고
    • An enzyme cascade in the blood clotting mechanism, and its function as a biochemical amplifier
    • R.G. Macfarlane An enzyme cascade in the blood clotting mechanism, and its function as a biochemical amplifier Nature 202 1964 498 499
    • (1964) Nature , vol.202 , pp. 498-499
    • MacFarlane, R.G.1
  • 5
    • 0032254001 scopus 로고    scopus 로고
    • The role of thrombin in hemostasis
    • B. Olas, and B. Wachowicz The role of thrombin in hemostasis Postepy Hig Med Dosw 52 1998 471 487
    • (1998) Postepy Hig Med Dosw , vol.52 , pp. 471-487
    • Olas, B.1    Wachowicz, B.2
  • 6
    • 34250782796 scopus 로고    scopus 로고
    • The central role of thrombin in hemostasis
    • DOI 10.1111/j.1538-7836.2007.02500.x, State of the Art 2007: XXI Congress of the International Society on Thrombosis and Haemostasis
    • J.T. Crawley, S. Zanardelli, C.K. Chion, and D.A. Lane The central role of thrombin in hemostasis J Thromb Haemost 5 Suppl 1 2007 95 101 (Pubitemid 46958822)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.SUPPL. 1 , pp. 95-101
    • Crawley, J.T.B.1    Zanardelli, S.2    Chion, C.K.N.K.3    Lane, D.A.4
  • 7
    • 0141484541 scopus 로고    scopus 로고
    • Thrombin interactions
    • E. Di Cera Thrombin interactions Chest 124 2003 11S 17S (Pubitemid 37128431)
    • (2003) Chest , vol.124 , Issue.SUPPL. 3
    • Di Cera, E.1
  • 8
    • 27144505651 scopus 로고    scopus 로고
    • Molecular recognition mechanisms of thrombin
    • DOI 10.1111/j.1538-7836.2005.01363.x
    • J.A. Huntington Molecular recognition mechanisms of thrombin J Thromb Haemost 3 2005 1861 1872 (Pubitemid 41716573)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.8 , pp. 1861-1872
    • Huntington, J.A.1
  • 10
    • 0029144243 scopus 로고
    • Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation
    • M. Hoffman, D.M. Monroe, J.A. Oliver, and H.R. Roberts Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation Blood 86 1995 1794 1801
    • (1995) Blood , vol.86 , pp. 1794-1801
    • Hoffman, M.1    Monroe, D.M.2    Oliver, J.A.3    Roberts, H.R.4
  • 13
    • 33846361749 scopus 로고    scopus 로고
    • Coagulation 2006: A Modern View of Hemostasis
    • DOI 10.1016/j.hoc.2006.11.004, PII S0889858806001882, Inflamation, Hemostasis, and Blood Conservation Strategies
    • M. Hoffman, and D.M. Monroe Coagulation 2006: a modern view of hemostasis Hematol Oncol Clin North Am 21 2007 1 11 (Pubitemid 46135905)
    • (2007) Hematology/Oncology Clinics of North America , vol.21 , Issue.1 , pp. 1-11
    • Hoffman, M.1    Monroe, D.M.2
  • 14
    • 34047229067 scopus 로고    scopus 로고
    • Thrombin generation and fibrin clot structure
    • DOI 10.1016/j.blre.2006.11.001, PII S0268960X0600066X
    • A.S. Wolberg Thrombin generation and fibrin clot structure Blood Rev 21 2007 131 142 (Pubitemid 46541695)
    • (2007) Blood Reviews , vol.21 , Issue.3 , pp. 131-142
    • Wolberg, A.S.1
  • 15
    • 28344448202 scopus 로고    scopus 로고
    • Fibrinogen and fibrin structure and functions
    • DOI 10.1111/j.1538-7836.2005.01365.x
    • M.W. Mosesson Fibrinogen and fibrin structure and functions J Thromb Haemost 3 2005 1894 1904 (Pubitemid 41716577)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.8 , pp. 1894-1904
    • Mosesson, M.W.1
  • 16
    • 0141707850 scopus 로고    scopus 로고
    • Thrombin and fibrinolysis
    • M. Nesheim Thrombin and fibrinolysis Chest 124 2003 33 39
    • (2003) Chest , vol.124 , pp. 33-39
    • Nesheim, M.1
  • 17
    • 0034972479 scopus 로고    scopus 로고
    • Factor XIII: Structure, activation, and interactions with fibrinogen and fibrin
    • L. Lorand Factor XIII: structure, activation, and interactions with fibrinogen and fibrin Ann NY Acad Sci 936 2001 291 311 (Pubitemid 32613915)
    • (2001) Annals of the New York Academy of Sciences , vol.936 , pp. 291-311
    • Lorand, L.1
  • 18
    • 0033675696 scopus 로고    scopus 로고
    • Thrombin activatable fibrinolysis inhibitor and an antifibrinolytic pathway
    • L. Bajzar Thrombin activatable fibrinolysis inhibitor and an antifibrinolytic pathway Arterioscler Thromb Vasc Biol 20 2000 2511 2518
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2511-2518
    • Bajzar, L.1
  • 20
    • 14044259258 scopus 로고    scopus 로고
    • Thrombin Activatable Fibrinolysis Inhibitor (TAFI) at the interface between coagulation and fibrinolysis
    • DOI 10.1159/000083832
    • B.N. Bouma, and L.O. Mosnier Thrombin activatable fibrinolysis inhibitor (TAFI) at the interface between coagulation and fibrinolysis Pathophysiol Haemost Thromb 33 2003 375 381 (Pubitemid 40278711)
    • (2003) Pathophysiology of Haemostasis and Thrombosis , vol.33 , Issue.5-6 , pp. 375-381
    • Bouma, B.N.1    Mosnier, L.O.2
  • 21
    • 0141498145 scopus 로고    scopus 로고
    • Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U)
    • B.N. Bouma, and J.C. Meijers Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U) J Thromb Haemost 1 2003 1566 1574
    • (2003) J Thromb Haemost , vol.1 , pp. 1566-1574
    • Bouma, B.N.1    Meijers, J.C.2
  • 24
    • 51449117497 scopus 로고    scopus 로고
    • Activated protein C-an anticoagulant that does more than stop clots
    • C.J. Jackson, and M. Xue Activated protein C-an anticoagulant that does more than stop clots Int J Biochem Cell Biol 40 2008 2692 2697
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 2692-2697
    • Jackson, C.J.1    Xue, M.2
  • 25
    • 18244417756 scopus 로고    scopus 로고
    • Molecular recognition in the protein C anticoagulant pathway
    • B. Dahlback, and B.O. Villoutreix Molecular recognition in the protein C anticoagulant pathway J Thromb Haemost 1 2003 1525 1534
    • (2003) J Thromb Haemost , vol.1 , pp. 1525-1534
    • Dahlback, B.1    Villoutreix, B.O.2
  • 26
    • 20444427991 scopus 로고    scopus 로고
    • The anticoagulant protein C pathway
    • DOI 10.1016/j.febslet.2005.03.001, PII S0014579305003066
    • B. Dahlback, and B.O. Villoutreix The anticoagulant protein C pathway FEBS Lett 579 2005 3310 3316 (Pubitemid 40804679)
    • (2005) FEBS Letters , vol.579 , Issue.15 , pp. 3310-3316
    • Dahlback, B.1    Villoutreix, B.O.2
  • 28
    • 33847010204 scopus 로고    scopus 로고
    • Heparin cofactor II modulates the response to vascular injury
    • D.M. Tollefsen Heparin cofactor II modulates the response to vascular injury Arterioscler Thromb Vasc Biol 27 2007 454 460
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 454-460
    • Tollefsen, D.M.1
  • 29
    • 38549100335 scopus 로고    scopus 로고
    • The haemostatic role of tissue factor pathway inhibitor
    • DOI 10.1161/ATVBAHA.107.141606, PII 0004360520080200000006
    • J.T. Crawley, and D.A. Lane The haemostatic role of tissue factor pathway inhibitor Arterioscler Thromb Vasc Biol 28 2008 233 242 (Pubitemid 351161194)
    • (2008) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.28 , Issue.2 , pp. 233-242
    • Crawley, J.T.B.1    Lane, D.A.2
  • 31
    • 14744287885 scopus 로고    scopus 로고
    • Polyphenols and prevention of cardiovascular diseases
    • C. Manach, A. Mazur, and A. Scalbert Polyphenols and prevention of cardiovascular diseases Curr Opin Lipidol 16 2005 77 84 (Pubitemid 40333370)
    • (2005) Current Opinion in Lipidology , vol.16 , Issue.1 , pp. 77-84
    • Manach, C.1    Mazur, A.2    Scalbert, A.3
  • 32
    • 26444588695 scopus 로고    scopus 로고
    • Cardioprotective effects of dietary polyphenols
    • T.L. Zern, and M.L. Fernandez Cardioprotective effects of dietary polyphenols J Nutr 135 2005 2291 2294 (Pubitemid 41429579)
    • (2005) Journal of Nutrition , vol.135 , Issue.10 , pp. 2291-2294
    • Zern, T.L.1    Fernandez, M.L.2
  • 33
    • 15244349331 scopus 로고    scopus 로고
    • Plant polyphenols: Modifiers of immune function and risk of cardiovascular disease
    • DOI 10.1016/j.nut.2004.11.003
    • D.A. Hughes Plant polyphenols: modifiers of immune function and risk of cardiovascular disease Nutrition 21 2005 422 423 (Pubitemid 40387945)
    • (2005) Nutrition , vol.21 , Issue.3 , pp. 422-423
    • Hughes, D.A.1
  • 35
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologic studies
    • I.C. Arts, and P.C. Hollman Polyphenols and disease risk in epidemiologic studies Am J Clin Nutr 81 2005 317 325
    • (2005) Am J Clin Nutr , vol.81 , pp. 317-325
    • Arts, I.C.1    Hollman, P.C.2
  • 36
    • 47249106944 scopus 로고    scopus 로고
    • Flavonoids and cardiovascular health: Which compounds, what mechanisms?
    • J.M. Geleijnse, and P.C. Hollman Flavonoids and cardiovascular health: which compounds, what mechanisms? Am J Clin Nutr 88 2008 12 13 (Pubitemid 351988676)
    • (2008) American Journal of Clinical Nutrition , vol.88 , Issue.1 , pp. 12-13
    • Geleijnse, J.M.1    Hollman, P.C.H.2
  • 37
    • 0001447059 scopus 로고
    • The phenolics constituents of Prunus domestica II
    • T. Swain, and W.E. Hillis The phenolics constituents of Prunus domestica II J Sci Food Agric 10 1959 135 138
    • (1959) J Sci Food Agric , vol.10 , pp. 135-138
    • Swain, T.1    Hillis, W.E.2
  • 38
    • 0035147348 scopus 로고    scopus 로고
    • Light and heat sensitivity of red cabbage extract in soft drink model systems
    • DOI 10.1016/S0308-8146(00)00251-X, PII S030881460000251X
    • M. Dyrby, N. Westergaard, and H. Stapelfeldt Light and heat sensitivity of red cabbage extract in soft drink model system Food Chem 10 2001 431 437 (Pubitemid 32120096)
    • (2001) Food Chemistry , vol.72 , Issue.4 , pp. 431-437
    • Dyrby, M.1    Westergaard, N.2    Stapelfeldt, H.3
  • 40
    • 36249027053 scopus 로고    scopus 로고
    • Different vulnerability of fibrinogen subunits to oxidative/nitrative modifications induced by peroxynitrite: Functional consequences
    • DOI 10.1016/j.thromres.2007.03.017, PII S004938480700120X
    • P. Nowak, H.M. Zbikowska, M. Ponczek, J. Kolodziejczyk, and B. Wachowicz Different vulnerability of fibrinogen subunits to oxidative/nitrative modifications induced by peroxynitrite: functional consequences Thromb Res 121 2007 163 174 (Pubitemid 350138069)
    • (2007) Thrombosis Research , vol.121 , Issue.2 , pp. 163-174
    • Nowak, P.1    Zbikowska, H.M.2    Ponczek, M.3    Kolodziejczyk, J.4    Wachowicz, B.5
  • 41
    • 0020378102 scopus 로고
    • The action of thrombin on peptide p-nitroanilide substrates: Hydrolysis of Tos-Gly-Pro-Arg-pNA and D-Phe-Pip-Arg-pNA by human and bovine and -thrombins
    • DOI 10.1016/0049-3848(82)90114-1
    • R. Lottenberg, J.A. Hall, J.W. Fenton, and C.M. Jackson The action of thrombin on peptide p-nitroanilide substrates: hydrolysis of Tos-Gly-Pro-Arg-pNA and D-Phe-Pip-Arg-pNA by human alpha and gamma and bovine alpha and beta-thrombins Thromb Res 28 1982 313 332 (Pubitemid 13254965)
    • (1982) Thrombosis Research , vol.28 , Issue.3 , pp. 313-332
    • Lottenberg, R.1    Hall, J.A.2    Fenton II, J.W.3    Jackson, C.M.4
  • 42
    • 0022919160 scopus 로고
    • Thrombin specificity with tripeptide chromogenic substrates: Comparison of human and bovine thrombins with and without fibrinogen clotting activities
    • S.A. Sonder, and J.W. Fenton Thrombin specificity with tripeptide chromogenic substrates: comparison of human and bovine thrombins with and without fibrinogen clotting activities Clin Chem 32 1986 934 937 (Pubitemid 17021151)
    • (1986) Clinical Chemistry , vol.32 , Issue.6 , pp. 934-937
    • Sonder, S.A.1    Fenton II, J.W.2
  • 44
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • C. Manach, G. Williamson, C. Morand, A. Scalbert, and C. Remesy Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies Am J Clin Nutr 81 2005 230 242
    • (2005) Am J Clin Nutr , vol.81 , pp. 230-242
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 46
    • 0036146735 scopus 로고    scopus 로고
    • Dietary flavonols: Chemistry, food content, and metabolism
    • DOI 10.1016/S0899-9007(01)00695-5, PII S0899900701006955
    • S.A. Aherne, and N.M. O'Brien Dietary flavonols: chemistry, food content, and metabolism Nutrition 18 2002 75 81 (Pubitemid 34097718)
    • (2002) Nutrition , vol.18 , Issue.1 , pp. 75-81
    • Aherne, S.A.1    O'Brien, N.M.2
  • 47
    • 0141863402 scopus 로고    scopus 로고
    • Overview of dietary flavonoids: Nomenclature, occurrence and intake
    • G.R. Beecher Overview of dietary flavonoids: nomenclature, occurrence and intake J Nutr 133 2003 3248 3254
    • (2003) J Nutr , vol.133 , pp. 3248-3254
    • Beecher, G.R.1
  • 48
    • 0036774226 scopus 로고    scopus 로고
    • Flavonoid antioxidants: Chemistry, metabolism and structure-activity relationships
    • DOI 10.1016/S0955-2863(02)00208-5, PII S0955286302002085
    • K.E. Heim, A.R. Tagliaferro, and D.J. Bobilya Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships J Nutr Biochem 13 2002 572 584 (Pubitemid 35246546)
    • (2002) Journal of Nutritional Biochemistry , vol.13 , Issue.10 , pp. 572-584
    • Heim, K.E.1    Tagliaferro, A.R.2    Bobilya, D.J.3
  • 49
    • 0029888128 scopus 로고    scopus 로고
    • Structure-antioxidant activity relationships of flavonoids and phenolic acids
    • DOI 10.1016/0891-5849(95)02227-9
    • C.A. Rice-Evans, N.J. Miller, and G. Paganga Structure-antioxidant activity relationships of flavonoids and phenolic acids Free Radic Biol Med 20 1996 933 956 (Pubitemid 26157509)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.7 , pp. 933-956
    • Rice-Evans, C.A.1    Miller, N.J.2    Paganga, G.3
  • 51
    • 56249107261 scopus 로고    scopus 로고
    • Chokeberry (Aronia melanocarpa) - A review on the characteristic components and potential health effect
    • S. Kulling, and H. Rawel Chokeberry (Aronia melanocarpa) - a review on the characteristic components and potential health effect Planta Med 74 2008 1625 1634
    • (2008) Planta Med , vol.74 , pp. 1625-1634
    • Kulling, S.1    Rawel, H.2
  • 53
    • 70449447952 scopus 로고    scopus 로고
    • An extract from berries of Aronia melanocarpa modulates the generation of superoxide anion radicals in blood platelets from breast cancer patients
    • M. Kedzierska, B. Olas, B. Wachowicz, A. Stochmal, W. Oleszek, A. Jeziorski, J. Piekarski, and R. Glowacki An extract from berries of Aronia melanocarpa modulates the generation of superoxide anion radicals in blood platelets from breast cancer patients Planta Med 75 2009 1405 1409
    • (2009) Planta Med , vol.75 , pp. 1405-1409
    • Kedzierska, M.1    Olas, B.2    Wachowicz, B.3    Stochmal, A.4    Oleszek, W.5    Jeziorski, A.6    Piekarski, J.7    Glowacki, R.8
  • 54
    • 77957978922 scopus 로고    scopus 로고
    • The nitrative and oxidative stress in blood platelets isolated from breast cancer patients: The protectory action of Aronia melanocarpa extract
    • M. Kedzierska, B. Olas, B. Wachowicz, A. Stochmal, W. Oleszek, A. Jeziorski, and J. Piekarski The nitrative and oxidative stress in blood platelets isolated from breast cancer patients: the protectory action of Aronia melanocarpa extract Platelets 21 2010 541 548
    • (2010) Platelets , vol.21 , pp. 541-548
    • Kedzierska, M.1    Olas, B.2    Wachowicz, B.3    Stochmal, A.4    Oleszek, W.5    Jeziorski, A.6    Piekarski, J.7
  • 56
    • 38649122031 scopus 로고    scopus 로고
    • Comparative anti-platelet and antioxidant properties of polyphenol-rich extracts from: Berries of Aronia melanocarpa, seeds of grape and bark of Yucca schidigera in vitro
    • DOI 10.1080/09537100701708506, PII 790036099
    • B. Olas, B. Wachowicz, A. Tomczak, J. Erler, A. Stochmal, and W. Oleszek Comparative anti-platelet and antioxidant properties of polyphenol-rich extracts from: berries of Aronia melanocarpa, seeds of grape and bark of Yucca schidigera in vitro Platelets 19 2008 70 77 (Pubitemid 351171558)
    • (2008) Platelets , vol.19 , Issue.1 , pp. 70-77
    • Olas, B.1    Wachowicz, B.2    Tomczak, A.3    Erler, J.4    Stochmal, A.5    Oleszek, W.6
  • 57
    • 28544445685 scopus 로고    scopus 로고
    • Wpyw antocyjanin z aronii czarnoowocowej na wybrane parametry stresu oksydacyjnego i zawartość mikroelementów u mȩzczyzn z hipercholesterolemia̧
    • E. Kowalczyk, P. Fijalkowski, M. Kura, P. Krzesinski, J. Blaszczyk, J. Kowalski, J. Smigielski, M. Rutkowski, and M. Kopff The influence of anthocyanins from Aronia melanocarpa on selected parameters of oxidative stress and microelements contents in men with hypercholesterolemia Pol Merkur Lekarski 19 2005 651 653 (Pubitemid 41743876)
    • (2005) Polski Merkuriusz Lekarski , vol.19 , Issue.113 , pp. 651-653
    • Kowalczyk, E.1    Fijalkowski, P.2    Kura, M.3    Krzesinski, P.4    Blaszczyk, J.5    Kowalski, J.6    Smigielski, J.7    Rutkowski, M.8    Kopff, M.9
  • 58
    • 34848877206 scopus 로고    scopus 로고
    • Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infraction (MI)
    • M. Naruszewicz, I. Laniewska, B. Millo, and M. Dluzniewski Combination therapy of statin with flavonoids rich extract from chokeberry fruits enhanced reduction in cardiovascular risk markers in patients after myocardial infraction (MI) Atherosclerosis 194 2007 179 184
    • (2007) Atherosclerosis , vol.194 , pp. 179-184
    • Naruszewicz, M.1    Laniewska, I.2    Millo, B.3    Dluzniewski, M.4
  • 59
    • 0034177677 scopus 로고    scopus 로고
    • Characterization of proanthocyanidins from grape seeds
    • DOI 10.1016/S0367-326X(99)00161-6, PII S0367326X99001616
    • B. Gabetta, N. Fuzzati, A. Griffini, E. Lolla, R. Pace, T. Ruffilli, and F. Peterlongo Characterization of proanthocyanidins from grape seeds Fitoterapia 71 2000 162 175 (Pubitemid 30156008)
    • (2000) Fitoterapia , vol.71 , Issue.2 , pp. 162-175
    • Gabetta, B.1    Fuzzati, N.2    Griffini, A.3    Lolla, E.4    Pace, R.5    Ruffilli, T.6    Peterlongo, F.7
  • 61
    • 55349089239 scopus 로고    scopus 로고
    • Cardioprotective actions of grape polyphenols
    • W.R. Leifert, and M.Y. Abeywardena Cardioprotective actions of grape polyphenols Nutr Res 28 2008 729 737
    • (2008) Nutr Res , vol.28 , pp. 729-737
    • Leifert, W.R.1    Abeywardena, M.Y.2
  • 62
    • 26044455886 scopus 로고    scopus 로고
    • Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates
    • DOI 10.1097/01.fjc.0000176727.67066.1c
    • O. Vitseva, S. Varghese, S. Chakrabarti, J.D. Folts, and J.E. Freedman Grape seed and skin extracts inhibit platelet function and release of reactive oxygen intermediates J Cardiovasc Pharmacol 46 2005 445 451 (Pubitemid 41407571)
    • (2005) Journal of Cardiovascular Pharmacology , vol.46 , Issue.4 , pp. 445-451
    • Vitseva, O.1    Varghese, S.2    Chakrabarti, S.3    Folts, J.D.4    Freedman, J.E.5
  • 63
    • 67349137045 scopus 로고    scopus 로고
    • Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity
    • I. Pawlaczyk, L. Czerchawski, W. Pilecki, E. Lamer-Zarawska, and R. Gancarz Polyphenolic-polysaccharide compounds from selected medicinal plants of Asteraceae and Rosaceae families: Chemical characterization and blood anticoagulant activity Carboh Pol 77 2009 568 575
    • (2009) Carboh Pol , vol.77 , pp. 568-575
    • Pawlaczyk, I.1    Czerchawski, L.2    Pilecki, W.3    Lamer-Zarawska, E.4    Gancarz, R.5
  • 65
    • 33748768976 scopus 로고    scopus 로고
    • Flavonoids inhibit theamidolytic activity ofhuman thrombin
    • DOI 10.1016/j.biochi.2006.04.007, PII S0300908406000575
    • M. Mozzicafreddo, M. Cuccioloni, A.M. Eleuteri, E. Fioretti, and M. Angeletti Flavonoids inhibit the amidolytic activity of human thrombin Biochimie 88 2006 1297 1306 (Pubitemid 44415203)
    • (2006) Biochimie , vol.88 , Issue.9 , pp. 1297-1306
    • Mozzicafreddo, M.1    Cuccioloni, M.2    Eleuteri, A.M.3    Fioretti, E.4    Angeletti, M.5
  • 67
    • 72949083999 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and the disturbance of haemostasis-facts and mythes
    • J. Malinowska, P. Nowak, and B. Olas Hyperhomocysteinemia and the disturbance of haemostasis-facts and mythes Pol Merkur Lekarski 27 2009 413 418
    • (2009) Pol Merkur Lekarski , vol.27 , pp. 413-418
    • Malinowska, J.1    Nowak, P.2    Olas, B.3
  • 68
    • 77954133782 scopus 로고    scopus 로고
    • May modifications of human plasma proteins stimulated by homocysteine and its thiolactone induce changes of hemostatic function of plasma in vitro?
    • B. Olas, J. Kolodziejczyk, and J. Malinowska May modifications of human plasma proteins stimulated by homocysteine and its thiolactone induce changes of hemostatic function of plasma in vitro? Gen Physiol Biophys 29 2010 186 193
    • (2010) Gen Physiol Biophys , vol.29 , pp. 186-193
    • Olas, B.1    Kolodziejczyk, J.2    Malinowska, J.3
  • 71
    • 79960080976 scopus 로고    scopus 로고
    • The importance of thrombin inhibitors in the antithrombotic pharmacotherapy
    • M. Bijak, and M. Bobrowski The importance of thrombin inhibitors in the antithrombotic pharmacotherapy Prog Med 10 2010 819 825
    • (2010) Prog Med , vol.10 , pp. 819-825
    • Bijak, M.1    Bobrowski, M.2
  • 73
    • 4644349854 scopus 로고    scopus 로고
    • Oral direct thrombin inhibition: An effective and novel approach for venous thromboembolism
    • DOI 10.2165/00003495-200464001-00003
    • S. Haas Oral direct thrombin inhibition: an effective and novel approach for venous thromboembolism Drugs 64 Suppl 1 2004 7 16 (Pubitemid 39280365)
    • (2004) Drugs , vol.64 , Issue.SUPPL. 1 , pp. 7-16
    • Haas, S.1
  • 74
    • 35248897610 scopus 로고    scopus 로고
    • Ximelagatran/melagatran against conventional anticoagulation: A meta-analysis based on 22,639 patients
    • DOI 10.1016/j.ijcard.2006.11.041, PII S0167527306014495
    • L. Testa, F. Andreotti, G.G. Biondi Zoccai, F. Burzotta, F. Bellocci, and F. Crea Ximelagatran/melagatran against conventional anticoagulation: a meta-analysis based on 22,639 patients Int J Cardiol 122 2007 117 124 (Pubitemid 47559087)
    • (2007) International Journal of Cardiology , vol.122 , Issue.2 , pp. 117-124
    • Testa, L.1    Andreotti, F.2    Biondi Zoccai, G.G.L.3    Burzotta, F.4    Bellocci, F.5    Crea, F.6
  • 75
    • 77951533737 scopus 로고    scopus 로고
    • Interactions between quercetin and warfarin for albumin binding: A new eye on food/drug interference
    • L. Di Bari, S. Ripoli, S. Pradhan, and P. Salvadori Interactions between quercetin and warfarin for albumin binding: a new eye on food/drug interference Chirality 22 2010 593 596
    • (2010) Chirality , vol.22 , pp. 593-596
    • Di Bari, L.1    Ripoli, S.2    Pradhan, S.3    Salvadori, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.