Cation-independent mannose 6-phosphate receptor inhibitor (PXs25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-β1

American Journal of Physiology - Renal Physiology

Volumn 301, Issue 1, 2011, Pages

  Wong, Muh Geot ^a   Panchapakesan, Usha ^a   Qi, Weier ^a   Silva, Diego G ^b   Chen, Xin Ming ^a   Pollock, Carol A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Frenchs Forest   (Australia)

Author keywords

Extracellular matrix; Hyperglycemia; Hypoxia

Indexed keywords

ANTIFIBROTIC AGENT; COLLAGEN TYPE 4; FIBRONECTIN; GELATINASE A; GELATINASE B; MANNOSE 6 PHOSPHATE RECEPTOR INHIBITOR; MATRIX PROTEIN; MESSENGER RNA; PXS 25; SMAD2 PROTEIN; SOMATOMEDIN B RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; FIBROSIS; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPOXIA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 79960067831     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00287.2010     Document Type: Article

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