Prolonged positive modulation of α-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid (AMPA) receptors induces calpain-mediated PSD-95/Dlg/ZO-1 protein degradation and AMPA receptor down-regulation in cultured hippocampal slices

Journal of Pharmacology and Experimental Therapeutics

Volumn 314, Issue 1, 2005, Pages 16-26

  Jourdi, Hussam ^a,b   Lu, Xiaoying ^a   Yanagihara, Ted ^b   Lauterborn, Julie C ^b   Bi, Xiaoning ^b   Gall, Christine M ^b   Baudry, Michel ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; BRAIN PROTEIN; CALPAIN; CALPASTATIN; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; GLUTAMATE RECEPTOR INTERACTING PROTEIN; IONOTROPIC RECEPTOR; IONOTROPIC RECEPTOR ANTAGONIST; LACTATE DEHYDROGENASE; MEMBRANE PROTEIN; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN ZO1; SYNAPSE ASSOCIATED PROTEIN 97; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME RELEASE; GENE EXPRESSION; GENE REPRESSION; HIPPOCAMPUS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; RAT; RECEPTOR DOWN REGULATION; SYNAPTIC TRANSMISSION;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CALPAIN; CARRIER PROTEINS; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXCITATORY AMINO ACID ANTAGONISTS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; L-LACTATE DEHYDROGENASE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; ORGAN CULTURE TECHNIQUES; OXAZINES; PROTEINS; RATS; RECEPTORS, AMPA; RNA, MESSENGER;

EID: 23044475486     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.105.083873     Document Type: Article

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