메뉴 건너뛰기




Volumn 121, Issue 7, 2011, Pages 2614-2624

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; FC RECEPTOR; FC RECEPTOR LIKE 4; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; LECTIN; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN 6; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 79960011154     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI45685     Document Type: Article
Times cited : (118)

References (40)
  • 1
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir S, Fauci AS. B cells in HIV infection and disease. Nat Rev Immunol. 2009;9(4):235-245.
    • (2009) Nat Rev Immunol , vol.9 , Issue.4 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 2
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir S, et al. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med. 2008;205(8):1797-1805.
    • (2008) J Exp Med , vol.205 , Issue.8 , pp. 1797-1805
    • Moir, S.1
  • 6
    • 57849168934 scopus 로고    scopus 로고
    • Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
    • Blackburn SD, et al. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol. 2009;10(1):29-37.
    • (2009) Nat Immunol , vol.10 , Issue.1 , pp. 29-37
    • Blackburn, S.D.1
  • 7
    • 0028997875 scopus 로고
    • Of ITAMs and ITIMs: Turning on and off the B cell antigen receptor
    • Thomas ML. Of ITAMs and ITIMs: turning on and off the B cell antigen receptor. J Exp Med. 1995;181(6):1953-1956.
    • (1995) J Exp Med , vol.181 , Issue.6 , pp. 1953-1956
    • Thomas, M.L.1
  • 8
    • 18844424394 scopus 로고    scopus 로고
    • The role of CD22 and other inhibitory co-receptors in B-cell activation
    • DOI 10.1016/j.coi.2005.03.005, PII S0952791505000439, Lymphocyte Activation/Lymphocyte Effector Functions
    • Nitschke L. The role of CD22 and other inhibitory co-receptors in B-cell activation. Curr Opin Immunol. 2005;17(3):290-297. (Pubitemid 40692664)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.3 , pp. 290-297
    • Nitschke, L.1
  • 9
    • 0036219193 scopus 로고    scopus 로고
    • Negative regulation of immunoreceptor signaling
    • DOI 10.1146/annurev.immunol.20.081501.130710
    • Veillette A, Latour S, Davidson D. Negative regulation of immunoreceptor signaling. Annu Rev Immunol. 2002;20:669-707. (Pubitemid 34293437)
    • (2002) Annual Review of Immunology , vol.20 , pp. 669-707
    • Veillette, A.1    Latour, S.2    Davidson, D.3
  • 10
    • 0037342154 scopus 로고    scopus 로고
    • B cell inhibitory receptors and autoimmunity
    • DOI 10.1046/j.1365-2567.2003.01592.x
    • Pritchard NR, Smith KG. B cell inhibitory receptors and autoimmunity. Immunology. 2003;108(3):263-273. (Pubitemid 36332384)
    • (2003) Immunology , vol.108 , Issue.3 , pp. 263-273
    • Pritchard, N.R.1    Smith, K.G.C.2
  • 14
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • DOI 10.1038/418244a
    • Hannon GJ. RNA interference. Nature. 2002;418(6894):244-251. (Pubitemid 34773784)
    • (2002) Nature , vol.418 , Issue.6894 , pp. 244-251
    • Hannon, G.J.1
  • 16
    • 34548138924 scopus 로고    scopus 로고
    • Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids
    • DOI 10.1038/sj.leu.2404863, PII 2404863
    • Seiffert M, Stilgenbauer S, Dohner H, Lichter P. Efficient nucleofection of primary human B cells and B-CLL cells induces apoptosis, which depends on the microenvironment and on the structure of transfected nucleic acids. Leukemia. 2007;21(9):1977-1983. (Pubitemid 47299973)
    • (2007) Leukemia , vol.21 , Issue.9 , pp. 1977-1983
    • Seiffert, M.1    Stilgenbauer, S.2    Dohner, H.3    Lichter, P.4
  • 17
    • 79959921364 scopus 로고    scopus 로고
    • Published 2009. Accessed May 9, 2011
    • Lonza. Amaxa Human B Cell Nucleofector Kit. 2009. http://www.lonzabio. com/resources/product-instructions/protocols/. Published 2009. Accessed May 9, 2011.
    • (2009) Amaxa Human B Cell Nucleofector Kit
  • 18
    • 79959921364 scopus 로고    scopus 로고
    • Published Accessed May 9, 2011
    • Lonza. Amaxa Human T Cell Nucleofector Kit. http://www.lonzabio.com/ resources/product-instructions/protocols/. Published 2009. Accessed May 9, 2011.
    • (2009) Amaxa Human T Cell Nucleofector Kit
  • 19
    • 0028851582 scopus 로고
    • The same tyrosine-based inhibition motif, in the intracytoplasmic domain of Fc gamma RIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation
    • Daeron M, et al. The same tyrosine-based inhibition motif, in the intracytoplasmic domain of Fc gamma RIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation. Immunity. 1995;3(5):635-646.
    • (1995) Immunity , vol.3 , Issue.5 , pp. 635-646
    • Daeron, M.1
  • 20
    • 62249172189 scopus 로고    scopus 로고
    • Enhancing SIV-specific immunity in vivo by PD-1 blockade
    • Velu V, et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature. 2009;458(7235):206-210.
    • (2009) Nature , vol.458 , Issue.7235 , pp. 206-210
    • Velu, V.1
  • 21
    • 77954684486 scopus 로고    scopus 로고
    • Complement receptor 2/CD21- Human naive B cells contain mostly autoreactive unresponsive clones
    • Isnardi I, et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood. 2010;115(24):5026-5036.
    • (2010) Blood , vol.115 , Issue.24 , pp. 5026-5036
    • Isnardi, I.1
  • 22
    • 0033178682 scopus 로고    scopus 로고
    • Surface molecule loss and bleb formation by human germinal center B cells undergoing apoptosis: Role of apoptotic blebs in monocyte chemotaxis
    • Segundo C, Medina F, Rodriguez C, Martinez-Palencia R, Leyva-Cobian F, Brieva JA. Surface molecule loss and bleb formation by human germinal center B cells undergoing apoptosis: role of apoptotic blebs in monocyte chemotaxis. Blood. 1999;94(3):1012-1020. (Pubitemid 29361833)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1012-1020
    • Segundo, C.1    Medina, F.2    Rodriguez, C.3    Martinez-Palencia, R.4    Leyva-Cobian, F.5    Brieva, J.A.6
  • 23
    • 37649019847 scopus 로고    scopus 로고
    • Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data
    • DOI 10.1038/nprot.2007.297, PII NPROT.2007.297
    • Hawkins ED, Hommel M, Turner ML, Battye FL, Markham JF, Hodgkin PD. Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nat Protoc. 2007;2(9):2057-2067. (Pubitemid 351565843)
    • (2007) Nature Protocols , vol.2 , Issue.9 , pp. 2057-2067
    • Hawkins, E.D.1    Hommel, M.2    Turner, M.L.3    Battye, F.L.4    Markham, J.F.5    Hodgkin, P.D.6
  • 24
    • 40449137383 scopus 로고    scopus 로고
    • CpG drives human transitional B cells to terminal differentiation and production of natural antibodies
    • Capolunghi F, et al. CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. J Immunol. 2008;180(2):800-808.
    • (2008) J Immunol , vol.180 , Issue.2 , pp. 800-808
    • Capolunghi, F.1
  • 25
    • 49049086136 scopus 로고    scopus 로고
    • CpG oligonucleotides enhance proliferative and effector responses of B cells in HIV-infected individuals
    • Malaspina A, et al. CpG oligonucleotides enhance proliferative and effector responses of B cells in HIV-infected individuals. J Immunol. 2008;181(2):1199-1206.
    • (2008) J Immunol , vol.181 , Issue.2 , pp. 1199-1206
    • Malaspina, A.1
  • 28
    • 76149139419 scopus 로고    scopus 로고
    • B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
    • Avery DT, et al. B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med. 2010;207(1):155-171.
    • (2010) J Exp Med , vol.207 , Issue.1 , pp. 155-171
    • Avery, D.T.1
  • 29
    • 77953359912 scopus 로고    scopus 로고
    • An optimized assay for the enumeration of antigen-specific memory B cells in different compartments of the human body
    • Cao Y, et al. An optimized assay for the enumeration of antigen-specific memory B cells in different compartments of the human body. J Immunol Methods. 2010;358(1-2):56-65.
    • (2010) J Immunol Methods , vol.358 , Issue.1-2 , pp. 56-65
    • Cao, Y.1
  • 30
    • 77953897004 scopus 로고    scopus 로고
    • Intrinsic properties of immunoglobulin IgG1 isotypeswitched B cell receptors promote microclustering and the initiation of signaling
    • Liu W, Meckel T, Tolar P, Sohn HW, Pierce SK. Intrinsic properties of immunoglobulin IgG1 isotypeswitched B cell receptors promote microclustering and the initiation of signaling. Immunity. 2010;32(6):778-789.
    • (2010) Immunity , vol.32 , Issue.6 , pp. 778-789
    • Liu, W.1    Meckel, T.2    Tolar, P.3    Sohn, H.W.4    Pierce, S.K.5
  • 33
    • 0037204949 scopus 로고    scopus 로고
    • B cell antigen receptor signaling: Roles in cell development and disease
    • DOI 10.1126/science.1071546
    • Gauld SB, Dal Porto JM, Cambier JC. B cell antigen receptor signaling: roles in cell development and disease. Science. 2002;296(5573):1641-1642. (Pubitemid 34579149)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1641-1642
    • Gauld, S.B.1    Dal, P.J.M.2    Cambier, J.C.3
  • 34
    • 2342499785 scopus 로고    scopus 로고
    • Ligand-independent tonic signaling in B-cell receptor function
    • DOI 10.1016/j.coi.2004.03.010, PII S0952791504000470
    • Monroe JG. Ligand-independent tonic signaling in B-cell receptor function. Curr Opin Immunol. 2004;16(3):288-295. (Pubitemid 38595367)
    • (2004) Current Opinion in Immunology , vol.16 , Issue.3 , pp. 288-295
    • Monroe, J.G.1
  • 35
    • 70350304558 scopus 로고    scopus 로고
    • PI3 kinase signals BCR-dependent mature B cell survival
    • Srinivasan L, et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell. 2009;139(3):573-586.
    • (2009) Cell , vol.139 , Issue.3 , pp. 573-586
    • Srinivasan, L.1
  • 36
    • 65349149089 scopus 로고    scopus 로고
    • Molecular mechanism and function of CD40/CD40L engagement in the immune system
    • Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol Rev. 2009;229(1):152-172.
    • (2009) Immunol Rev , vol.229 , Issue.1 , pp. 152-172
    • Elgueta, R.1    Benson, M.J.2    De Vries, V.C.3    Wasiuk, A.4    Guo, Y.5    Noelle, R.J.6
  • 37
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
    • Bolland S, Ravetch JV. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity. 2000;13(2):277-285.
    • (2000) Immunity , vol.13 , Issue.2 , pp. 277-285
    • Bolland, S.1    Ravetch, J.V.2
  • 38
    • 49249105303 scopus 로고    scopus 로고
    • Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors
    • Cady CT, Rice JS, Ott VL, Cambier JC. Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors. Immunol Rev. 2008;224:44-57.
    • (2008) Immunol Rev , vol.224 , pp. 44-57
    • Cady, C.T.1    Rice, J.S.2    Ott, V.L.3    Cambier, J.C.4
  • 39
    • 78049434917 scopus 로고    scopus 로고
    • Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques
    • Titanji K, et al. Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques. J Clin Invest. 2010;120(11):3878-3890.
    • (2010) J Clin Invest , vol.120 , Issue.11 , pp. 3878-3890
    • Titanji, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.