Thymidylate synthase expression and genotype have no major impact on the clinical outcome of colorectal cancer patients treated with 5-fluorouracil

Pharmacological Research

Volumn 64, Issue 3, 2011, Pages 242-248

  Vignoli, Marina ^a,b   Nobili, Stefania ^b   Napoli, Cristina ^b   Putignano, Anna Laura ^a,b   Morganti, Maria ^b   Papi, Laura ^b   Valanzano, Rosa ^b   Cianchi, Fabio ^b   Tonelli, Francesco ^b   Mazzei, Teresita ^b   Mini, Enrico ^b   Genuardi, Maurizio ^a,b  

^a Fondazione Farmacogenomica Fiorgen   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

5 Fluorouracil; Colorectal cancer; Genotype; mRNA expression; Thymidylate synthase

Indexed keywords

FLUOROURACIL; MESSENGER RNA; THYMIDYLATE SYNTHASE;

5' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; REGULATOR GENE; TANDEM REPEAT; THYMIDYLATE SYNTHASE GENE; TREATMENT OUTCOME;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOTYPE; HUMANS; MALE; MIDDLE AGED; THYMIDYLATE SYNTHASE; YOUNG ADULT;

EID: 79959997023     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.04.006     Document Type: Article

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