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Volumn 61, Issue 4, 2011, Pages 770-777

Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors

Author keywords

Antipsychotic; Crosstalk; Dopamine D2 receptor; Hallucinogen; Schizophrenia; Serotonin 5 HT2A receptor

Indexed keywords

DIZOCILPINE; DOPAMINE 2 RECEPTOR; INOSITOL PHOSPHATE; SEROTONIN 2A RECEPTOR;

EID: 79959993845     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.05.023     Document Type: Article
Times cited : (95)

References (50)
  • 1
    • 28244475354 scopus 로고    scopus 로고
    • Transmembrane signaling in the brain by serotonin, a key regulator of physiology and emotion
    • DOI 10.1007/s10540-005-2896-3
    • T. Adayev, B. Ranasinghe, and P. Banerjee Transmembrane signaling in the brain by serotonin, a key regulator of physiology and emotion Biosci. Rep. 25 2005 363 385 (Pubitemid 41712664)
    • (2005) Bioscience Reports , vol.25 , Issue.5-6 , pp. 363-385
    • Adayev, T.1    Ranasinghe, B.2    Banerjee, P.3
  • 2
    • 33751195311 scopus 로고    scopus 로고
    • Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding
    • L. Albizu, M.N. Balestre, C. Breton, J.P. Pin, M. Manning, and B. Mouillac Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding Mol. Pharmacol. 70 2006 1783 1791
    • (2006) Mol. Pharmacol. , vol.70 , pp. 1783-1791
    • Albizu, L.1    Balestre, M.N.2    Breton, C.3    Pin, J.P.4    Manning, M.5    Mouillac, B.6
  • 3
    • 34948854685 scopus 로고    scopus 로고
    • Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands
    • DOI 10.1021/jm061404q
    • L. Albizu, G. Teppaz, R. Seyer, H. Bazin, H. Ansanay, and M. Manning Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands J. Med. Chem. 50 2007 4976 4985 (Pubitemid 47527131)
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.20 , pp. 4976-4985
    • Albizu, L.1    Teppaz, G.2    Seyer, R.3    Bazin, H.4    Ansanay, H.5    Manning, M.6    Mouillac, B.7    Durroux, T.8
  • 5
    • 78649299930 scopus 로고    scopus 로고
    • Heteromerization of G protein-coupled receptors: Relevance to neurological disorders and neurotherapeutics
    • L. Albizu, J.L. Moreno, J. Gonzalez-Maeso, and S.C. Sealfon Heteromerization of G protein-coupled receptors: relevance to neurological disorders and neurotherapeutics CNS Neurol. Disord. Drug Targets 9 2010 636 650
    • (2010) CNS Neurol. Disord. Drug Targets , vol.9 , pp. 636-650
    • Albizu, L.1    Moreno, J.L.2    Gonzalez-Maeso, J.3    Sealfon, S.C.4
  • 7
    • 0035933747 scopus 로고    scopus 로고
    • Dopamine D2 receptor dimer formation: Evidence from ligand binding
    • D. Armstrong, and P.G. Strange Dopamine D2 receptor dimer formation: evidence from ligand binding J. Biol. Chem. 276 2001 22621 22629
    • (2001) J. Biol. Chem. , vol.276 , pp. 22621-22629
    • Armstrong, D.1    Strange, P.G.2
  • 8
    • 0141841603 scopus 로고    scopus 로고
    • Dual inhibition of β-adrenergic and angiotensin II receptors by a single antagonist: A functional role for receptor-receptor interaction in vivo
    • DOI 10.1161/01.CIR.0000092166.30360.78
    • L. Barki-Harrington, L.M. Luttrell, and H.A. Rockman Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo Circulation 108 2003 1611 1618 (Pubitemid 37187789)
    • (2003) Circulation , vol.108 , Issue.13 , pp. 1611-1618
    • Barki-Harrington, L.1    Luttrell, L.M.2    Rockman, H.A.3
  • 10
    • 28044457735 scopus 로고    scopus 로고
    • 2A receptors in prefrontal cortex enhances dopaminergic activity
    • DOI 10.1111/j.1471-4159.2005.03485.x
    • A. Bortolozzi, L. Diaz-Mataix, M.C. Scorza, P. Celada, and F. Artigas The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity J. Neurochem. 95 2005 1597 1607 (Pubitemid 41804057)
    • (2005) Journal of Neurochemistry , vol.95 , Issue.6 , pp. 1597-1607
    • Bortolozzi, A.1    Diaz-Mataix, L.2    Scorza, M.C.3    Celada, P.4    Artigas, F.5
  • 11
    • 78649966665 scopus 로고    scopus 로고
    • Dopamine in motivational control: Rewarding, aversive, and alerting
    • E.S. Bromberg-Martin, M. Matsumoto, and O. Hikosaka Dopamine in motivational control: rewarding, aversive, and alerting Neuron 68 2010 815 834
    • (2010) Neuron , vol.68 , pp. 815-834
    • Bromberg-Martin, E.S.1    Matsumoto, M.2    Hikosaka, O.3
  • 12
    • 14644387575 scopus 로고    scopus 로고
    • Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation
    • DOI 10.1016/j.tips.2005.01.004
    • S. Bulenger, S. Marullo, and M. Bouvier Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation Trends Pharmacol. Sci. 26 2005 131 137 (Pubitemid 40313592)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.3 , pp. 131-137
    • Bulenger, S.1    Marullo, S.2    Bouvier, M.3
  • 13
    • 0021248714 scopus 로고
    • Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex
    • DOI 10.1016/0028-3908(84)90017-0
    • P.J. Conn, and E. Sanders-Bush Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex Neuropharmacology 23 1984 993 996 (Pubitemid 14097227)
    • (1984) Neuropharmacology , vol.23 , Issue.8 , pp. 993-996
    • Conn, P.J.1    Sanders-Bush, E.2
  • 14
    • 20344373575 scopus 로고
    • The role of serotonin in neurobiology
    • E. Costa The role of serotonin in neurobiology Int. Rev. Neurobiol. 2 1960 175 227
    • (1960) Int. Rev. Neurobiol. , vol.2 , pp. 175-227
    • Costa, E.1
  • 16
    • 50349102197 scopus 로고    scopus 로고
    • Distribution of 5-HT and da receptors in primate prefrontal cortex: Implications for pathophysiology and treatment
    • J. de Almeida, J.M. Palacios, and G. Mengod Distribution of 5-HT and DA receptors in primate prefrontal cortex: implications for pathophysiology and treatment Prog. Brain Res. 172 2008 101 115
    • (2008) Prog. Brain Res. , vol.172 , pp. 101-115
    • De Almeida, J.1    Palacios, J.M.2    Mengod, G.3
  • 17
    • 0034640439 scopus 로고    scopus 로고
    • Ultrastructural localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area
    • DOI 10.1016/S0006-8993(00)02062-X, PII S000689930002062X
    • M.D. Doherty, and V.M. Pickel Ultrastructural localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area Brain Res. 864 2000 176 185 (Pubitemid 30235099)
    • (2000) Brain Research , vol.864 , Issue.2 , pp. 176-185
    • Doherty, M.D.1    Pickel, V.M.2
  • 18
    • 20544449873 scopus 로고    scopus 로고
    • Principles: A model for the allosteric interactions between ligand binding sites within a dimeric GPCR
    • DOI 10.1016/j.tips.2005.05.006, PII S0165614705001306
    • T. Durroux Principles: a model for the allosteric interactions between ligand binding sites within a dimeric GPCR Trends Pharmacol. Sci. 26 2005 376 384 (Pubitemid 40848499)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.7 , pp. 376-384
    • Durroux, T.1
  • 19
    • 34548530597 scopus 로고    scopus 로고
    • Functional relevance of neurotransmitter receptor heteromers in the central nervous system
    • DOI 10.1016/j.tins.2007.07.001, PII S0166223607001762
    • S. Ferre, F. Ciruela, A.S. Woods, C. Lluis, and R. Franco Functional relevance of neurotransmitter receptor heteromers in the central nervous system Trends Neurosci. 30 2007 440 446 (Pubitemid 47381459)
    • (2007) Trends in Neurosciences , vol.30 , Issue.9 , pp. 440-446
    • Ferre, S.1    Ciruela, F.2    Woods, A.S.3    Lluis, C.4    Franco, R.5
  • 20
    • 0028179448 scopus 로고
    • Effects of zotepine, haloperidol and clozapine on MK-801-induced stereotypy and locomotion in rats
    • W.F. Gattaz, B. Schummer, and S. Behrens Effects of zotepine, haloperidol and clozapine on MK-801-induced stereotypy and locomotion in rats J. Neural Transm. Gen. Sect. 96 1994 227 232
    • (1994) J. Neural Transm. Gen. Sect. , vol.96 , pp. 227-232
    • Gattaz, W.F.1    Schummer, B.2    Behrens, S.3
  • 21
    • 50249108916 scopus 로고    scopus 로고
    • On the fitting of binding data when receptor dimerization is suspected
    • J. Giraldo On the fitting of binding data when receptor dimerization is suspected Br. J. Pharmacol. 155 2008 17 23
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 17-23
    • Giraldo, J.1
  • 25
    • 39149104024 scopus 로고    scopus 로고
    • GPCR monomers and oligomers: It takes all kinds
    • V.V. Gurevich, and E.V. Gurevich GPCR monomers and oligomers: it takes all kinds Trends Neurosci. 31 2008 74 81
    • (2008) Trends Neurosci. , vol.31 , pp. 74-81
    • Gurevich, V.V.1    Gurevich, E.V.2
  • 26
    • 0029620775 scopus 로고
    • The role of serotonin in schizophrenia
    • DOI 10.1016/0924-977X(95)00027-M
    • N. Iqbal, and H.M. van Praag The role of serotonin in schizophrenia Eur. Neuropsychopharmacol. 1995 11 23 (Suppl. 5) (Pubitemid 26022214)
    • (1995) European Neuropsychopharmacology , vol.5 , Issue.SUPPL. , pp. 11-23
    • Iqbal, N.1    Van Praag, H.M.2
  • 27
    • 0033578005 scopus 로고    scopus 로고
    • G-protein-coupled receptor heterodimerization modulates receptor function
    • DOI 10.1038/21441
    • B.A. Jordan, and L.A. Devi G-protein-coupled receptor heterodimerization modulates receptor function Nature 399 1999 697 700 (Pubitemid 29289066)
    • (1999) Nature , vol.399 , Issue.6737 , pp. 697-700
    • Jordan, B.A.1    Devi, L.A.2
  • 28
    • 0027251133 scopus 로고
    • The dopamine hypothesis of schizophrenia: Limbic interactions with serotonin and norepinephrine
    • J.N. Joyce The dopamine hypothesis of schizophrenia: limbic interactions with serotonin and norepinephrine Psychopharmacology (Berl) 112 1993 S16 S34
    • (1993) Psychopharmacology (Berl) , vol.112
    • Joyce, J.N.1
  • 29
    • 0029988896 scopus 로고    scopus 로고
    • Serotonin-dopamine interaction and its relevance to schizophrenia
    • S. Kapur, and G. Remington Serotonin-dopamine interaction and its relevance to schizophrenia Am. J. Psychiatry 153 1996 466 476 (Pubitemid 26113309)
    • (1996) American Journal of Psychiatry , vol.153 , Issue.4 , pp. 466-476
    • Kapur, S.1    Remington, G.2
  • 33
    • 0035078362 scopus 로고    scopus 로고
    • The neurobiology and genetics of suicide and attempted suicide: A focus on the serotonergic system
    • DOI 10.1016/S0893-133X(00)00228-1, PII S0893133X00002281
    • J.J. Mann, D.A. Brent, and V. Arango The neurobiology and genetics of suicide and attempted suicide: a focus on the serotonergic system Neuropsychopharmacology 24 2001 467 477 (Pubitemid 32244308)
    • (2001) Neuropsychopharmacology , vol.24 , Issue.5 , pp. 467-477
    • Mann, J.J.1    Brent, D.A.2    Arango, V.3
  • 34
    • 0021824455 scopus 로고
    • Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting
    • R. Mattera, B.J. Pitts, M.L. Entman, and L. Birnbaumer Guanine nucleotide regulation of a mammalian myocardial muscarinic receptor system. Evidence for homo- and heterotropic cooperativity in ligand binding analyzed by computer-assisted curve fitting J. Biol. Chem. 260 1985 7410 7421 (Pubitemid 15063016)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.12 , pp. 7410-7421
    • Mattera, R.1    Pitts, B.J.R.2    Entman, M.L.3    Birnbaumer, L.4
  • 36
    • 69249206623 scopus 로고    scopus 로고
    • Protein-coupled receptor hetero-dimerization: Contribution to pharmacology and function
    • G.G. Milligan Protein-coupled receptor hetero-dimerization: contribution to pharmacology and function Br. J. Pharmacol. 158 2009 5 14
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 5-14
    • Milligan, G.G.1
  • 37
    • 0027509776 scopus 로고
    • Preferential coupling between dopamine D2 receptors and G-proteins
    • DOI 10.1210/me.7.2.161
    • J.P. Montmayeur, J. Guiramand, and E. Borrelli Preferential coupling between dopamine D2 receptors and G-proteins Mol. Endocrinol. 7 1993 161 170 (Pubitemid 23066858)
    • (1993) Molecular Endocrinology , vol.7 , Issue.2 , pp. 161-170
    • Montmayeur, J.-P.1    Guiramand, J.2    Borrelli, E.3
  • 38
    • 0842324481 scopus 로고    scopus 로고
    • Hallucinogens
    • DOI 10.1016/j.pharmthera.2003.11.002
    • D.E. Nichols Hallucinogens Pharmacol. Ther. 101 2004 131 181 (Pubitemid 38167565)
    • (2004) Pharmacology and Therapeutics , vol.101 , Issue.2 , pp. 131-181
    • Nichols, D.E.1
  • 39
    • 44849104847 scopus 로고    scopus 로고
    • Serotonin receptors
    • DOI 10.1021/cr078224o
    • D.E. Nichols, and C.D. Nichols Serotonin receptors Chem. Rev. 108 2008 1614 1641 (Pubitemid 351796401)
    • (2008) Chemical Reviews , vol.108 , Issue.5 , pp. 1614-1641
    • Nichols, D.E.1    Nichols, C.D.2
  • 40
    • 0037156476 scopus 로고    scopus 로고
    • 2A receptors on dopamine cells in subnuclei of the midbrain A10 cell group
    • DOI 10.1016/S0306-4522(01)00593-0, PII S0306452201005930
    • C. Nocjar, B.L. Roth, and E.A. Pehek Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group Neuroscience 111 2002 163 176 (Pubitemid 34310459)
    • (2002) Neuroscience , vol.111 , Issue.1 , pp. 163-176
    • Nocjar, C.1    Roth, B.L.2    Pehek, E.3
  • 41
    • 0022401097 scopus 로고
    • Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors
    • DOI 10.1016/0006-8993(85)90857-1
    • A. Pazos, R. Cortes, and J.M. Palacios Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors Brain Res. 346 1985 231 249 (Pubitemid 16241112)
    • (1985) Brain Research , vol.346 , Issue.2 , pp. 231-249
    • Pazos, A.1    Cortes, R.2    Palacios, J.M.3
  • 42
    • 0022596083 scopus 로고
    • The use of MK-801, a novel sympathomimetic, in adults with attention deficit disorder, residual type
    • F.W. Reimherr, D.R. Wood, and P.H. Wender The use of MK-801, a novel sympathomimetic, in adults with attention deficit disorder, residual type Psychopharmacol. Bull. 22 1986 237 242 (Pubitemid 16101363)
    • (1986) Psychopharmacology Bulletin , vol.22 , Issue.1 , pp. 237-242
    • Reimherr, F.W.1    Wood, D.R.2    Wender, P.H.3
  • 43
    • 68249159980 scopus 로고    scopus 로고
    • Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration
    • M.L. Rives, C. Vol, Y. Fukazawa, N. Tinel, E. Trinquet, and M.A. Ayoub Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration Embo J. 28 2009 2195 2208
    • (2009) Embo J. , vol.28 , pp. 2195-2208
    • Rives, M.L.1    Vol, C.2    Fukazawa, Y.3    Tinel, N.4    Trinquet, E.5    Ayoub, M.A.6
  • 44
    • 77649096828 scopus 로고    scopus 로고
    • Receptor heteromerization and drug discovery
    • R. Rozenfeld, and L.A. Devi Receptor heteromerization and drug discovery Trends Pharmacol. Sci. 31 2010 124 130
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 124-130
    • Rozenfeld, R.1    Devi, L.A.2
  • 45
    • 33645802812 scopus 로고    scopus 로고
    • Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers
    • J.Y. Springael, P.N. Le Minh, E. Urizar, S. Costagliola, G. Vassart, and M. Parmentier Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers Mol. Pharmacol. 69 2006 1652 1661
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1652-1661
    • Springael, J.Y.1    Le Minh, P.N.2    Urizar, E.3    Costagliola, S.4    Vassart, G.5    Parmentier, M.6
  • 46
    • 1242276192 scopus 로고    scopus 로고
    • Roles of G-protein-coupled receptor dimerization
    • DOI 10.1038/sj.embor.7400052
    • S. Terrillon, and M. Bouvier Roles of G-protein-coupled receptor dimerization Embo Rep. 5 2004 30 34 (Pubitemid 38228524)
    • (2004) EMBO Reports , vol.5 , Issue.1 , pp. 30-34
    • Terrillon, S.1    Bouvier, M.2
  • 48
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • DOI 10.1038/35072566
    • M.L. Wong, and J. Licinio Research and treatment approaches to depression Nat. Rev. Neurosci. 2 2001 343 351 (Pubitemid 33680576)
    • (2001) Nature Reviews Neuroscience , vol.2 , Issue.5 , pp. 343-351
    • Wong, M.-L.1    Licinio, J.2
  • 49
    • 0029083945 scopus 로고
    • Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors
    • K.A. Wreggett, and J.W. Wells Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors J. Biol. Chem. 270 1995 22488 22499
    • (1995) J. Biol. Chem. , vol.270 , pp. 22488-22499
    • Wreggett, K.A.1    Wells, J.W.2


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