Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response

Neuropharmacology

Volumn 61, Issue 4, 2011, Pages 608-613

  Komatsu, Takaaki ^a   Mizoguchi, Hirokazu ^b   Sasaki, Mika ^a   Sakurada, Chikai ^c   Tsuzuki, Minoru ^c   Sakurada, Shinobu ^b   Sakurada, Tsukasa ^a  

^a DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Capsaicin induced nociceptive response; Extracellular signal regulated protein kinase (ERK); Intrathecal injection; N Terminal fragments of substance P; Spinal antinociception

Indexed keywords

CAPSAICIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHENYLALANINE; PROLINE; STRESS ACTIVATED PROTEIN KINASE; SUBSTANCE P;

AMINO TERMINAL SEQUENCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MALE; MOUSE; NERVE POTENTIAL; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT RESPONSE;

ANIMALS; BEHAVIOR, ANIMAL; CAPSAICIN; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INJECTIONS, SPINAL; MALE; MAP KINASE SIGNALING SYSTEM; MICE; PAIN; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; SUBSTANCE P;

EID: 79959965433     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.04.035     Document Type: Article

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