In silico modeling of the Menkes copper-translocating P-type ATPase 3rd metal binding domain predicts that phosphorylation regulates copper-binding

BioMetals

Volumn 24, Issue 3, 2011, Pages 477-487

  Veldhuis, N A ^a   Kuiper, M J ^c   Dobson, R C J ^d,e   Pearson, R B ^a   Camakaris, J ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Victorian Partnership of Advanced Computing   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF CANTERBURY   (New Zealand)

^e PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

ATP7A; Menkes copper translocating P type ATPase; Metal binding domain 3; Molecular dynamics; Phosphorylation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COPPER ION; MENKES PROTEIN; PROTEIN MBD3; SERINE; THREONINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; BINDING AFFINITY; BINDING SITE; COMPUTER MODEL; CONCENTRATION RESPONSE; CONFERENCE PAPER; ESCHERICHIA COLI; METAL BINDING; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN STRUCTURE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BINDING SITES; CATION TRANSPORT PROTEINS; COPPER; ENZYME STABILITY; MENKES KINKY HAIR SYNDROME; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHORYLATION; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; STATIC ELECTRICITY;

EID: 79959962166     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-011-9410-0     Document Type: Conference Paper

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