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Volumn 39, Issue 3, 2011, Pages 683-688

Hypermethylation of promoter regions of the APC1A and p16 INK4a genes in relation to prognosis and tumor characteristics in cervical cancer patients

Author keywords

APC1A; Cervical squamous cell carcinoma; DNA methylation; p16; Prognosis

Indexed keywords

PROTEIN P16;

EID: 79959932532     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1078     Document Type: Article
Times cited : (16)

References (43)
  • 1
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • DOI 10.1200/JCO.2004.07.151
    • Das PM and Singal R: DNA methylation and cancer. J Clin Oncol 22: 4632-4642, 2004. (Pubitemid 41185132)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 2
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A: DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21, 2002.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 3
    • 0028988143 scopus 로고
    • O6-methylguanine-DNA methyltransferase activity in breast and brain tumors
    • Preuss I, Eberhagen I, Haas S, et al: O6-methylguanine-DNA methyltransferase activity in breast and brain tumors. Int J Cancer 61: 321-326, 1995.
    • (1995) Int J Cancer , vol.61 , pp. 321-326
    • Preuss, I.1    Eberhagen, I.2    Haas, S.3
  • 4
    • 0033622180 scopus 로고    scopus 로고
    • Incidence of p14(arf) gene deletion in high-grade adult and pediatric astrocytomas
    • Newcomb EW, Alonso M, Sung T and Miller DC: Incidence of p14ARF gene deletion in high-grade adult and pediatric astrocytomas. Hum Pathol 31: 115-119, 2000. (Pubitemid 30054396)
    • (2000) Human Pathology , vol.31 , Issue.1 , pp. 115-119
    • Newcomb, E.W.1    Alonso, M.2    Sung, T.3    Miller, D.C.4
  • 5
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • DOI 10.1038/366704a0
    • Serrano M, Hannon GJ and Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707, 1993. (Pubitemid 24036021)
    • (1993) Nature , vol.366 , Issue.6456 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 8
    • 0027756014 scopus 로고
    • Association of the APC tumor suppressor protein with catenins
    • Su LK, Vogelstein B and Kinzler KW: Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737, 1993. (Pubitemid 24030097)
    • (1993) Science , vol.262 , Issue.5140 , pp. 1734-1737
    • Su, L.-K.1    Vogelstein, B.2    Kinzler, K.W.3
  • 11
    • 64849085626 scopus 로고    scopus 로고
    • Development of Pyrosequencing assays to study promoter CpG site methylation of the O6-MGMT, hMLH1, p14ARF, p16INK4a, RASSF1A, and APC1A genes
    • Löf-Öhlin Z and Nilsson T: Development of Pyrosequencing assays to study promoter CpG site methylation of the O6-MGMT, hMLH1, p14ARF, p16INK4a, RASSF1A, and APC1A genes. Oncol Rep 21: 721-729, 2009.
    • (2009) Oncol Rep , vol.21 , pp. 721-729
    • Löf-Öhlin, Z.1    Nilsson, T.2
  • 12
    • 0038678777 scopus 로고    scopus 로고
    • Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites
    • Colella S, Shen L, Baggerly KA, Issa JP and Krahe R: Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques 35: 146-150, 2003. (Pubitemid 36828724)
    • (2003) BioTechniques , vol.35 , Issue.1 , pp. 146-150
    • Colella, S.1    Shen, L.2    Baggerly, K.A.3    Issa, J.-P.J.4    Krahe, R.5
  • 13
    • 0036962761 scopus 로고    scopus 로고
    • Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis
    • DOI 10.1002/elps.200290023
    • Uhlmann K, Brinckmann A, Toliat MR, Ritter H and Nurnberg P: Evaluation of a potential epigenetic biomarker by quantitative methyl-single nucleotide polymorphism analysis. Electrophoresis 23: 4072-4079, 2002. (Pubitemid 36131460)
    • (2002) Electrophoresis , vol.23 , Issue.24 , pp. 4072-4079
    • Uhlmann, K.1    Brinckmann, A.2    Toliat, M.R.3    Ritter, H.4    Nurnberg, P.5
  • 14
    • 39049181307 scopus 로고    scopus 로고
    • Analysis of gene-specific DNA methylation patterns by pyrosequencing™ technology
    • Tost J and Gut IG: Analysis of gene-specific DNA methylation patterns by pyrosequencing™ technology. Methods Mol Biol 373: 89-102, 2006.
    • (2006) Methods Mol Biol , vol.373 , pp. 89-102
    • Tost, J.1    Gut, I.G.2
  • 15
    • 4444346815 scopus 로고    scopus 로고
    • De novo quantitative bisulfite sequencing using the pyrosequencing technology
    • DOI 10.1016/j.ab.2004.05.007, PII S0003269704004130
    • Dupont JM, Tost J, Jammes H and Gut IG: De novo quantitative bisulfite sequencing using the pyrosequencing technology. Anal Biochem 333: 119-127, 2004. (Pubitemid 39209229)
    • (2004) Analytical Biochemistry , vol.333 , Issue.1 , pp. 119-127
    • Dupont, J.-M.1    Tost, J.2    Jammes, H.3    Gut, I.G.4
  • 16
    • 34247273521 scopus 로고    scopus 로고
    • Rare CpG Island Methylator Phenotype in Ulcerative Colitis-Associated Neoplasias
    • DOI 10.1053/j.gastro.2007.01.035, PII S0016508507001734
    • Konishi K, Shen L, Wang S, Meltzer SJ, Harpaz N and Issa JP: Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. Gastroenterology 132: 1254-1260, 2007. (Pubitemid 46627571)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1254-1260
    • Konishi, K.1    Shen, L.2    Wang, S.3    Meltzer, S.J.4    Harpaz, N.5    Issa, J.J.6
  • 17
    • 33846783308 scopus 로고    scopus 로고
    • Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis
    • DOI 10.1677/erc.1.01294
    • Fontaniere S, Tost J, Wierinckx A, et al: Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis. Endocr Relat Cancer 13: 1223-1236, 2006. (Pubitemid 46212576)
    • (2006) Endocrine-Related Cancer , vol.13 , Issue.4 , pp. 1223-1236
    • Fontaniere, S.1    Tost, J.2    Wierinckx, A.3    Lachuer, J.4    Lu, J.5    Hussein, N.6    Busato, F.7    Gut, I.8    Wang, Z.-Q.9    Zhang, C.-X.10
  • 18
    • 34247559653 scopus 로고    scopus 로고
    • Methods for detecting DNA methylation in tumors: From bench to bedside
    • DOI 10.1016/j.canlet.2006.10.014, PII S0304383506005738
    • Shames DS, Minna JD and Gazdar AF: Methods for detecting DNA methylation in tumors: From bench to bedside. Cancer Lett 251: 187-198, 2007. (Pubitemid 46669792)
    • (2007) Cancer Letters , vol.251 , Issue.2 , pp. 187-198
    • Shames, D.S.1    Minna, J.D.2    Gazdar, A.F.3
  • 20
    • 33846031979 scopus 로고    scopus 로고
    • Quantitative high-resolution CpG island mapping with pyrosequencing reveals disease-specific methylation patterns of the CDKN2B gene in myelodysplastic syndrome and myeloid leukemia
    • DOI 10.1373/clinchem.2007.072629
    • Brakensiek K, Wingen LU, Langer F, Kreipe H and Lehmann U: Quantitative high-resolution CpG island mapping with Pyrosequencing reveals disease-specific methylation patterns of the CDKN2B gene in myelodysplastic syndrome and myeloid leukemia. Clin Chem 53: 17-23, 2007. (Pubitemid 46047759)
    • (2007) Clinical Chemistry , vol.53 , Issue.1 , pp. 17-23
    • Brakensiek, K.1    Wingen, L.U.2    Langer, F.3    Kreipe, H.4    Lehmann, U.5
  • 21
    • 33846217828 scopus 로고    scopus 로고
    • Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer
    • DOI 10.1002/mc.20258
    • Wang LG, Beklemisheva A, Liu XM, Ferrari AC, Feng J and Chiao JW: Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer. Mol Carcinog 46: 24-31, 2007. (Pubitemid 46095230)
    • (2007) Molecular Carcinogenesis , vol.46 , Issue.1 , pp. 24-31
    • Wang, L.G.1    Beklemisheva, A.2    Liu, X.M.3    Ferrari, A.C.4    Feng, J.5    Chiao, J.W.6
  • 22
    • 32044461294 scopus 로고    scopus 로고
    • Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay
    • DOI 10.1101/gr.4181406
    • Cheng YW, Shawber C, Notterman D, Paty P and Barany F: Multiplexed profiling of candidate genes for CpG island methylation status using a flexible PCR/LDR/Universal Array assay. Genome Res 16: 282-289, 2006. (Pubitemid 43200277)
    • (2006) Genome Research , vol.16 , Issue.2 , pp. 282-289
    • Cheng, Y.-W.1    Shawber, C.2    Notterman, D.3    Paty, P.4    Barany, F.5
  • 23
    • 33847026146 scopus 로고    scopus 로고
    • Changes in DNA methylation patterns in subjects exposed to low-dose benzene
    • Bollati V, Baccarelli A, Hou L, et al: Changes in DNA methylation patterns in subjects exposed to low-dose benzene. Cancer Res 67: 876-880, 2007.
    • (2007) Cancer Res , vol.67 , pp. 876-880
    • Bollati, V.1    Baccarelli, A.2    Hou, L.3
  • 26
    • 33646937122 scopus 로고    scopus 로고
    • Quantitative analysis of SRNPN gene methylation by pyrosequencing as a diagnostic test for Prader-Willi syndrome and Angelman syndrome
    • DOI 10.1373/clinchem.2005.065086
    • White HE, Durston VJ, Harvey JF and Cross NC: Quantitative analysis of SNRPN (correction of SRNPN) gene methylation by pyrosequencing as a diagnostic test for Prader-Willi syndrome and Angelman syndrome. Clin Chem 52: 1005-1013, 2006. (Pubitemid 43794410)
    • (2006) Clinical Chemistry , vol.52 , Issue.6 , pp. 1005-1013
    • White, H.E.1    Durston, V.J.2    Harvey, J.F.3    Cross, N.C.P.4
  • 27
    • 40849116456 scopus 로고    scopus 로고
    • Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins
    • DOI 10.1038/sj.mp.4002001, PII 4002001
    • Kuratomi G, Iwamoto K, Bundo M, et al: Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol Psychiatry 13: 429-441, 2008. (Pubitemid 351399814)
    • (2008) Molecular Psychiatry , vol.13 , Issue.4 , pp. 429-441
    • Kuratomi, G.1    Iwamoto, K.2    Bundo, M.3    Kusumi, I.4    Kato, N.5    Iwata, N.6    Ozaki, N.7    Kato, T.8
  • 28
    • 33745039815 scopus 로고    scopus 로고
    • Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene
    • DOI 10.1002/ajmg.b.30316
    • Mill J, Dempster E, Caspi A, Williams B, Moffitt T and Craig I: Evidence for monozygotic twin (MZ) discordance in methylation level at two CpG sites in the promoter region of the catechol-O-methyltransferase (COMT) gene. Am J Med Genet B Neuropsychiatr Genet 141: 421-425, 2006. (Pubitemid 43872897)
    • (2006) American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics , vol.141 , Issue.4 , pp. 421-425
    • Mill, J.1    Dempster, E.2    Caspi, A.3    Williams, B.4    Moffitt, T.5    Craig, I.6
  • 29
    • 58149154845 scopus 로고    scopus 로고
    • Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis
    • Lee JS, Fackler MJ, Teo WW, et al: Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis. Cancer Biol Ther 7: 1398-1346, 2007.
    • (2007) Cancer Biol Ther , vol.7 , pp. 1398-11346
    • Lee, J.S.1    Fackler, M.J.2    Teo, W.W.3
  • 30
    • 42249099793 scopus 로고    scopus 로고
    • Heterogeneity of breast cancer metastases: Comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases
    • Wu JM, Fackler MJ, Halushka MK, et al: Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases. Clin Cancer Res 14: 1938-1946, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 1938-1946
    • Wu, J.M.1    Fackler, M.J.2    Halushka, M.K.3
  • 31
    • 55949118381 scopus 로고    scopus 로고
    • Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype
    • Van der Auwera I, Van Laere SJ, Van den Bosch SM, et al: Aberrant methylation of the Adenomatous Polyposis Coli (APC) gene promoter is associated with the inflammatory breast cancer phenotype. Br J Cancer 99: 1735-1742, 2008.
    • (2008) Br J Cancer , vol.99 , pp. 1735-1742
    • Van Der Auwera, I.1    Van Laere, S.J.2    Van Den Bosch, S.M.3
  • 33
    • 67650340970 scopus 로고    scopus 로고
    • Promoter methylation in APC, RUNX3, and GSTP1 and mortality in prostate cancer patients
    • Richiardi L, Fiano V, Vizzini L, et al: Promoter methylation in APC, RUNX3, and GSTP1 and mortality in prostate cancer patients. J Clin Oncol 27: 3161-3168, 2009.
    • (2009) J Clin Oncol , vol.27 , pp. 3161-3168
    • Richiardi, L.1    Fiano, V.2    Vizzini, L.3
  • 35
  • 36
    • 75649143716 scopus 로고    scopus 로고
    • APC promoter hypermethylation is an early event in endometrial tumorigenesis
    • Ignatov A, Bischoff J, Ignatov T, et al: APC promoter hypermethylation is an early event in endometrial tumorigenesis. Cancer Sci 101: 321-327, 2010.
    • (2010) Cancer Sci , vol.101 , pp. 321-327
    • Ignatov, A.1    Bischoff, J.2    Ignatov, T.3
  • 37
    • 70449592332 scopus 로고    scopus 로고
    • Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients
    • Supic G, Kozomara R, Brankovic-Magic M, Jovic N and Magic Z: Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients. Oral Oncol 45: 1051-1057, 2009.
    • (2009) Oral Oncol , vol.45 , pp. 1051-1057
    • Supic, G.1    Kozomara, R.2    Brankovic-Magic, M.3    Jovic, N.4    Magic, Z.5
  • 38
    • 60549100565 scopus 로고    scopus 로고
    • Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus
    • Kim YT, Park JY, Jeon YK, et al: Aberrant promoter CpG island hypermethylation of the adenomatosis polyposis coli gene can serve as a good prognostic factor by affecting lymph node metastasis in squamous cell carcinoma of the esophagus. Dis Esophag 22: 143-150, 2009.
    • (2009) Dis Esophag , vol.22 , pp. 143-150
    • Kim, Y.T.1    Park, J.Y.2    Jeon, Y.K.3
  • 39
    • 41049096579 scopus 로고    scopus 로고
    • APC promoter methylation and protein expression in hepatocellular carcinoma
    • Csepregi A, Röcken C, Hoffmann J, et al: APC promoter methylation and protein expression in hepatocellular carcinoma. J Cancer Res Clin Oncol 134: 579-589, 2008.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 579-589
    • Csepregi, A.1    Röcken, C.2    Hoffmann, J.3
  • 40
    • 67049096814 scopus 로고    scopus 로고
    • The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients
    • Chen SP, Chiu SC, Wu CC, et al: The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. Genet Test Mol Biomarkers 13: 67-71, 2009.
    • (2009) Genet Test Mol Biomarkers , vol.13 , pp. 67-71
    • Chen, S.P.1    Chiu, S.C.2    Wu, C.C.3
  • 41
    • 58849128287 scopus 로고    scopus 로고
    • Hydralazine inhibits human cervical cancer cell growth in vitro in association with APC demethylation and re-expression
    • Song Y and Zhang C: Hydralazine inhibits human cervical cancer cell growth in vitro in association with APC demethylation and re-expression. Cancer Chemother Pharmacol 63: 605-613, 2009.
    • (2009) Cancer Chemother Pharmacol , vol.63 , pp. 605-613
    • Song, Y.1    Zhang, C.2
  • 42
    • 70349301437 scopus 로고    scopus 로고
    • APC as a master regulator of intestinal homeostasis and transformation
    • Cordero J, Vidal M and Sansom O: APC as a master regulator of intestinal homeostasis and transformation. Cell Cycle 8: 2927-2932, 2008.
    • (2008) Cell Cycle , vol.8 , pp. 2927-2932
    • Cordero, J.1    Vidal, M.2    Sansom, O.3
  • 43
    • 65549159598 scopus 로고    scopus 로고
    • A two-step model for colon adenoma initiation and progression caused by APC loss
    • Phelps RA, Chidester S, Dehghanizadeh S, et al: A two-step model for colon adenoma initiation and progression caused by APC loss. Cell 137: 623-634, 2009.
    • (2009) Cell , vol.137 , pp. 623-634
    • Phelps, R.A.1    Chidester, S.2    Dehghanizadeh, S.3


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