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Volumn 66, Issue 7, 2002, Pages 1615-1617

Binding selectivity of conformationally restricted analogues of (−)-indolactam-v to the c1 domains of protein kinase C isozymes

Author keywords

( ) indolactam V; Isozyme selective binding; Phorbol ester; Protein kinase C; Tumor promoter

Indexed keywords

INDOLACTAM V; INDOLE DERIVATIVE; ISOENZYME; LACTAM; PROTEIN KINASE C;

EID: 0036654782     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.66.1615     Document Type: Article
Times cited : (20)

References (11)
  • 1
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka, Y., Protein kinase C and lipid signaling for sustained cellular responses. FASEB J., 9, 484-496 (1995).
    • (1995) FASEB J. , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 2
    • 0032847677 scopus 로고    scopus 로고
    • Protein kinase C in the treatment of disease: Signal transduction pathways, inhibitors, and agents in development
    • Goekjian, P. G., and Jirousek, M. R., Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development. Curr. Med. Chem., 6, 877-903 (1999).
    • (1999) Curr. Med. Chem. , vol.6 , pp. 877-903
    • Goekjian, P.G.1    Jirousek, M.R.2
  • 4
    • 0034903846 scopus 로고    scopus 로고
    • Toward the identification of selective modulators of protein kinase C (PKC) isozymes: Establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding
    • Shindo, M., Irie, K., Nakahara, A., Ohigashi, H., Konishi, H., Kikkawa, U., Fukuda, H., and Wender, P. A., Toward the identification of selective modulators of protein kinase C (PKC) isozymes: establishment of a binding assay for PKC isozymes using synthetic C1 peptide receptors and identification of the critical residues involved in the phorbol ester binding. BioMed. Chem., 9, 2073-2081 (2001).
    • (2001) Biomed. Chem. , vol.9 , pp. 2073-2081
    • Shindo, M.1    Irie, K.2    Nakahara, A.3    Ohigashi, H.4    Konishi, H.5    Kikkawa, U.6    Fukuda, H.7    Wender, P.A.8
  • 5
    • 0021258634 scopus 로고
    • The Epstein-Barr virus early antigen inducing indole alkaloids, (-)-indolactam-V and its related compounds produced by Actinomycetes
    • Irie, K., Hirota, M., Hagiwara, N., Koshimizu, K., Hayashi, H., Murao, S., Tokuda, H., and Ito, Y., The Epstein-Barr virus early antigen inducing indole alkaloids, (-)-indolactam-V and its related compounds produced by Actinomycetes. Agric. Biol. Chem., 48, 1269-1274 (1984).
    • (1984) Agric. Biol. Chem. , vol.48 , pp. 1269-1274
    • Irie, K.1    Hirota, M.2    Hagiwara, N.3    Koshimizu, K.4    Hayashi, H.5    Murao, S.6    Tokuda, H.7    Ito, Y.8
  • 6
    • 0000052202 scopus 로고
    • Synthesis and stereochemistry of indolac-tam-V, an active fragment of teleocidins. Structural requirements for tumor-promoting activity
    • Endo, Y., Shudo, K., Itai, A., Hasegawa, M., and Sakai, S., Synthesis and stereochemistry of indolac-tam-V, an active fragment of teleocidins. Structural requirements for tumor-promoting activity. Tetrahedron, 42, 5905-5924 (1986).
    • (1986) Tetrahedron , vol.42 , pp. 5905-5924
    • Endo, Y.1    Shudo, K.2    Itai, A.3    Hasegawa, M.4    Sakai, S.5
  • 7
    • 0033822235 scopus 로고    scopus 로고
    • Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V
    • Nakagawa, Y., Irie, K., Ohigashi, H., Hayashi, H., and Wender, P. A., Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V. BioMed. Chem. Lett., 10, 2087-2090 (2000).
    • (2000) Biomed. Chem. Lett. , vol.10 , pp. 2087-2090
    • Nakagawa, Y.1    Irie, K.2    Ohigashi, H.3    Hayashi, H.4    Wender, P.A.5
  • 8
    • 10544240767 scopus 로고    scopus 로고
    • Synthesis and biological activities of new conformationally restricted analogues of (-)-indolactam-V: Elucidation of the biologically active conformation of the tumor-promoting teleocidins
    • Irie, K., Isaka, T., Iwata, Y., Yanai, Y., Nakamura, Y., Koizumi, F., Ohigashi, H., Wender, P. A., Satomi, Y., and Nishino, H., Synthesis and biological activities of new conformationally restricted analogues of (-)-indolactam-V: elucidation of the biologically active conformation of the tumor-promoting teleocidins. J. Am. Chem. Soc., 118, 10733-10743 (1996).
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 10733-10743
    • Irie, K.1    Isaka, T.2    Iwata, Y.3    Yanai, Y.4    Nakamura, Y.5    Koizumi, F.6    Ohigashi, H.7    Wender, P.A.8    Satomi, Y.9    Nishino, H.10
  • 9
    • 0027297104 scopus 로고
    • Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes
    • Kazanietz, M. G., Areces, L. B., Bahador, A., Mischak, H., Goodnight, J., Mushinski, J. F., and Blumberg, P. M., Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Mol. Pharmacol., 44, 298-307 (1993).
    • (1993) Mol. Pharmacol. , vol.44 , pp. 298-307
    • Kazanietz, M.G.1    Areces, L.B.2    Bahador, A.3    Mischak, H.4    Goodnight, J.5    Mushinski, J.F.6    Blumberg, P.M.7
  • 10
    • 0032211130 scopus 로고    scopus 로고
    • The role of protein kinase C signaling in activated DRA transcription
    • Setterblad, N., Onyango, I., Pihlgren, U., Rask, L., and Andersson, G., The role of protein kinase C signaling in activated DRA transcription. J. Immunol., 161, 4819-4824 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 4819-4824
    • Setterblad, N.1    Onyango, I.2    Pihlgren, U.3    Rask, L.4    Andersson, G.5
  • 11
    • 0034776809 scopus 로고    scopus 로고
    • Protein kinase C isozymes, novel phorbol ester receptors and cancer chemotherapy
    • Barry, O. P., and Kazanietz, M. G., Protein kinase C isozymes, novel phorbol ester receptors and cancer chemotherapy, Curr. Pharm. Design, 7, 1725-1744 (2001).
    • (2001) Curr. Pharm. Design , vol.7 , pp. 1725-1744
    • Barry, O.P.1    Kazanietz, M.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.