메뉴 건너뛰기




Volumn 6, Issue 2, 2011, Pages 139-146

Latent tuberculosis: Is there a role for thioridazine?

Author keywords

Dormancy; Latent tuberculosis; MDR; Mycobacteria; Respiration; Thioridazine. XDR

Indexed keywords

PHENOTHIAZINE DERIVATIVE; THIORIDAZINE;

EID: 79959929330     PISSN: 1574891X     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489111796064551     Document Type: Article
Times cited : (14)

References (96)
  • 1
    • 77952326903 scopus 로고    scopus 로고
    • The population dynamics and control of tuberculosis
    • Dye C, Williams BG. The population dynamics and control of tuberculosis. Science 2010; 328: 856-61.
    • (2010) Science , vol.328 , pp. 856-861
    • Dye, C.1    Williams, B.G.2
  • 2
    • 77956216718 scopus 로고    scopus 로고
    • Understanding latent tuberculosis: A moving target
    • Lin PL, Flynn JL. Understanding latent tuberculosis: A moving target. J Immun 2010; 185: 15-22.
    • (2010) J Immun , vol.185 , pp. 15-22
    • Lin, P.L.1    Flynn, J.L.2
  • 3
    • 67349255827 scopus 로고    scopus 로고
    • Dynamic or minimally recrudescent? on the elusive nature and location of the mycobacterium responsible for latent tuberculosis
    • Ehlers SL. Dynamic or minimally recrudescent? on the elusive nature and location of the mycobacterium responsible for latent tuberculosis. Infection 2009.
    • (2009) Infection
    • Ehlers, S.L.1
  • 4
    • 77952356637 scopus 로고    scopus 로고
    • Tuberculosis: What we don't know can, and does, hurt us
    • Russell DG, Barry CEI, Flynn JL. Tuberculosis: What we don't know can, and does, hurt us. Science 2010; 328: 852-6.
    • (2010) Science , vol.328 , pp. 852-856
    • Russell, D.G.1    Barry, C.E.I.2    Flynn, J.L.3
  • 5
    • 0034780485 scopus 로고    scopus 로고
    • Nonreplicating persistence of Mycobacterium tuberculosis
    • Wayne LG, Sohaskey CD. Nonreplicating persistence of Mycobacterium tuberculosis. Ann Rev Microbiol 2001; 55: 139-63.
    • (2001) Ann Rev Microbiol , vol.55 , pp. 139-163
    • Wayne, L.G.1    Sohaskey, C.D.2
  • 6
    • 0042140672 scopus 로고    scopus 로고
    • Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis persistence program
    • Voskuil MI, Schnappinger D, Harrell MI, Visconti KC, Dolganov GM, Sherman DR, et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis persistence program. J Exp Med 2003; 198(5): 705-13.
    • (2003) J Exp Med , vol.198 , Issue.5 , pp. 705-713
    • Voskuil, M.I.1    Schnappinger, D.2    Harrell, M.I.3    Visconti, K.C.4    Dolganov, G.M.5    Sherman, D.R.6
  • 8
    • 0001327976 scopus 로고
    • The bacteriology of resected tuberculous pulmonary lesions. II. Observations on bacilli which are stainable but which cannot be cultured
    • Wayne LG. The bacteriology of resected tuberculous pulmonary lesions. II. Observations on bacilli which are stainable but which cannot be cultured. Am Rev Resp Dis 1960; 82(3): 370-7.
    • (1960) Am Rev Resp Dis , vol.82 , Issue.3 , pp. 370-377
    • Wayne, L.G.1
  • 9
    • 0000610130 scopus 로고
    • The Bacteriology of resected tuberculous pulmonary lesions
    • Wayne LG, Salkin D. The Bacteriology of resected tuberculous pulmonary lesions. Amer Rev Tuber Pulm Dis 1956; 74(3): 376-87.
    • (1956) Amer Rev Tuber Pulm Dis , vol.74 , Issue.3 , pp. 376-387
    • Wayne, L.G.1    Salkin, D.2
  • 10
    • 0001776002 scopus 로고
    • Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions
    • Opie EAJ. Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions. Arch Pathol Lab Med 1927; 4: 1-21.
    • (1927) Arch Pathol Lab Med , vol.4 , pp. 1-21
    • Opie, E.A.J.1
  • 11
    • 0001011816 scopus 로고
    • Types of Tubercle bacilli in human tuberculosis
    • Griffith AS. Types of Tubercle bacilli in human tuberculosis. J Pathol Bacteriol 1929; 32: 813-40.
    • (1929) J Pathol Bacteriol , vol.32 , pp. 813-840
    • Griffith, A.S.1
  • 12
    • 0006643537 scopus 로고
    • The occurrence of virulent Tubercle bacilli in presumably non-tuberculous lung tissue
    • Feldman WH, Baggenstoss AH. The occurrence of virulent Tubercle bacilli in presumably non-tuberculous lung tissue. Amer J Pathol 1939; 15(5): 501-15.
    • (1939) Amer J Pathol , vol.15 , Issue.5 , pp. 501-515
    • Feldman, W.H.1    Baggenstoss, A.H.2
  • 13
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
    • Barry CEI, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn J, et al. The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies. Nat Rev Microbiol 2009; 7: 845-55.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 845-855
    • Barry, C.E.I.1    Boshoff, H.I.2    Dartois, V.3    Dick, T.4    Ehrt, S.5    Flynn, J.6
  • 15
    • 0034502343 scopus 로고    scopus 로고
    • Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection
    • Hernández-Pando R, Jeyanathan M, Mengistu G, Aguilar D, Orozco H, Harboe M, et al. Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 2000; 356: 2133-7.
    • (2000) Lancet , vol.356 , pp. 2133-2137
    • Hernández-Pando, R.1    Jeyanathan, M.2    Mengistu, G.3    Aguilar, D.4    Orozco, H.5    Harboe, M.6
  • 17
    • 11144250804 scopus 로고    scopus 로고
    • Tuberculosis - metabolism and respiration in the absence of growth
    • Boshoff HIM, Barry CEI. Tuberculosis - metabolism and respiration in the absence of growth. Nat Rev 2005; 3: 70-80.
    • (2005) Nat Rev , vol.3 , pp. 70-80
    • Boshoff, H.I.M.1    Barry, C.E.I.2
  • 18
    • 77957946456 scopus 로고    scopus 로고
    • Letting Sleeping dos Lie: Does dormancy play a role in tuberculosis
    • Chao MC, Rubin EJ. Letting Sleeping dos Lie: Does dormancy play a role in tuberculosis. Ann Rev Microbiol 2010; 64: 293-311.
    • (2010) Ann Rev Microbiol , vol.64 , pp. 293-311
    • Chao, M.C.1    Rubin, E.J.2
  • 21
    • 27344432975 scopus 로고    scopus 로고
    • Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration
    • Shi L, Sohaskey CD, Kana BD, Dawes S, North RJ, Mizrahi V, et al. Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration. Proc Natl Acad Sci USA 2005; 102(43): 15529-34.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.43 , pp. 15529-15534
    • Shi, L.1    Sohaskey, C.D.2    Kana, B.D.3    Dawes, S.4    North, R.J.5    Mizrahi, V.6
  • 22
    • 0037422617 scopus 로고    scopus 로고
    • Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence
    • Shi L, Jung Y-J, Tyagi S, Gennaro ML, North R. Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence. Proc Natl Acad Sci USA 2003; 100(1): 241-6.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.1 , pp. 241-246
    • Shi, L.1    Jung, Y.-J.2    Tyagi, S.3    Gennaro, M.L.4    North, R.5
  • 23
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional Adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
    • Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, et al. Transcriptional Adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment. J Exp Med 2003; 198(5): 693-704.
    • (2003) J Exp Med , vol.198 , Issue.5 , pp. 693-704
    • Schnappinger, D.1    Ehrt, S.2    Voskuil, M.I.3    Liu, Y.4    Mangan, J.A.5    Monahan, I.M.6
  • 24
    • 0035205354 scopus 로고    scopus 로고
    • Characterization of the cydAB-Encoded Cytochrome bd Oxidase from Mycobacterium smegmatis
    • Kana BD, Weinstein EA, Avarbock D, Dawes SS, Rubin H, Mizrahi V. Characterization of the cydAB-Encoded Cytochrome bd Oxidase from Mycobacterium smegmatis. J Bacteriol 2001; 183(24): 7076-86.
    • (2001) J Bacteriol , vol.183 , Issue.24 , pp. 7076-7086
    • Kana, B.D.1    Weinstein, E.A.2    Avarbock, D.3    Dawes, S.S.4    Rubin, H.5    Mizrahi, V.6
  • 25
    • 0344666693 scopus 로고    scopus 로고
    • Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterium tuberculosis
    • Sohaskey CD, Wayne LG. Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterium tuberculosis. J Bacteriol 2003; 185(24): 7247-56.
    • (2003) J Bacteriol , vol.185 , Issue.24 , pp. 7247-7256
    • Sohaskey, C.D.1    Wayne, L.G.2
  • 26
    • 27744462809 scopus 로고    scopus 로고
    • Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide
    • Sohaskey CD. Regulation of nitrate reductase activity in Mycobacterium tuberculosis by oxygen and nitric oxide. Microbiol 2005; 151(11): 3803-10.
    • (2005) Microbiol , vol.151 , Issue.11 , pp. 3803-3810
    • Sohaskey, C.D.1
  • 27
    • 84960961533 scopus 로고
    • The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug
    • McCune RMJ, McDermott W, Tompsett R. The fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. II. The conversion of tuberculous infection to the latent state by the administration of pyrazinamide and a companion drug. J Exp Med 1956; 104(5): 763-802.
    • (1956) J Exp Med , vol.104 , Issue.5 , pp. 763-802
    • McCune, R.M.J.1    McDermott, W.2    Tompsett, R.3
  • 30
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
    • Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, Eum SY, et al. Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates. Infect Immun 2008; 76(6): 2332-40.
    • (2008) Infect Immun , vol.76 , Issue.6 , pp. 2332-2340
    • Via, L.E.1    Lin, P.L.2    Ray, S.M.3    Carrillo, J.4    Allen, S.S.5    Eum, S.Y.6
  • 31
    • 33644832153 scopus 로고    scopus 로고
    • Characterization of the tuberculous granuloma in murine and human lungs: Cellular composition and relative tissue oxygen tension
    • Tsai MC, Chakravarty S, Zhu G, Xu J, Tanaka K, Koch C, et al. Characterization of the tuberculous granuloma in murine and human lungs: Cellular composition and relative tissue oxygen tension. Cell Microbiol 2006; 8(2): 218-32.
    • (2006) Cell Microbiol , vol.8 , Issue.2 , pp. 218-232
    • Tsai, M.C.1    Chakravarty, S.2    Zhu, G.3    Xu, J.4    Tanaka, K.5    Koch, C.6
  • 32
    • 0019973896 scopus 로고
    • Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions
    • Wayne LG, Lin K-Y. Glyoxylate metabolism and adaptation of Mycobacterium tuberculosis to survival under anaerobic conditions. Infect Immun 1982; 37(3): 1042-9.
    • (1982) Infect Immun , vol.37 , Issue.3 , pp. 1042-1049
    • Wayne, L.G.1    Lin, K.-Y.2
  • 33
    • 0029976980 scopus 로고    scopus 로고
    • An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence
    • Wayne LG, Hayes LG. An in vitro model for sequential study of shiftdown of Mycobacterium tuberculosis through two stages of nonreplicating persistence. Infect Immun 1996; 64(6): 2062-9.
    • (1996) Infect Immun , vol.64 , Issue.6 , pp. 2062-2069
    • Wayne, L.G.1    Hayes, L.G.2
  • 34
    • 4544312369 scopus 로고    scopus 로고
    • The transcriptional responses of Mycobacterium tuberculosis to Inhibitors of Metabolism
    • Boshoff HIM, Myers TG, Copp BR, McNeil MR, Wilson MA, Barry CEI. The transcriptional responses of Mycobacterium tuberculosis to Inhibitors of Metabolism. J Biol Chem 2004; 279(38): 40174-84.
    • (2004) J Biol Chem , vol.279 , Issue.38 , pp. 40174-40184
    • Boshoff, H.I.M.1    Myers, T.G.2    Copp, B.R.3    McNeil, M.R.4    Wilson, M.A.5    Barry, C.E.I.6
  • 35
    • 3042706671 scopus 로고    scopus 로고
    • Gene expression profile of Mycobacterium tuberculosis in a nonreplicating state
    • Muttucumaru DG, Roberts G, Hinds J, Stabler RA, Parish T. Gene expression profile of Mycobacterium tuberculosis in a nonreplicating state. Tuberculosis 2004; 84: 239-46.
    • (2004) Tuberculosis , vol.84 , pp. 239-246
    • Muttucumaru, D.G.1    Roberts, G.2    Hinds, J.3    Stabler, R.A.4    Parish, T.5
  • 36
    • 41949097208 scopus 로고    scopus 로고
    • Nitrate enhances the survival of Mycobacterium tuberculosis during inhibition of respiration
    • Sohaskey CD. Nitrate enhances the survival of Mycobacterium tuberculosis during inhibition of respiration. J Bacteriol 2008; 190(8): 2981-86.
    • (2008) J Bacteriol , vol.190 , Issue.8 , pp. 2981-2986
    • Sohaskey, C.D.1
  • 37
    • 43049182981 scopus 로고    scopus 로고
    • The enduring hypoxic response of Mycobacterium tuberculosis
    • Rustad TR, Harrell MI, Liao R, Sherman DR. The enduring hypoxic response of Mycobacterium tuberculosis. PLOS One 2008; 3(1): 1-8.
    • (2008) PLOS One , vol.3 , Issue.1 , pp. 1-8
    • Rustad, T.R.1    Harrell, M.I.2    Liao, R.3    Sherman, D.R.4
  • 39
    • 0038349268 scopus 로고    scopus 로고
    • Rv3133c/dosR is a transcription factor that mediates the hypoxic response of M. tuberculosis
    • Park H-D, Guinn KM, Harrell MI, Liao R, Voskuil M, Tompa M, et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of M. tuberculosis. Mol Microbiol 2003; 48(3): 833-43.
    • (2003) Mol Microbiol , vol.48 , Issue.3 , pp. 833-843
    • Park, H.-D.1    Guinn, K.M.2    Harrell, M.I.3    Liao, R.4    Voskuil, M.5    Tompa, M.6
  • 40
    • 0042825331 scopus 로고    scopus 로고
    • A family of acr-Coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for Expression
    • Florczyk MA, McCue LA, Purkayastha A, Currenti E, Wolin MJ, McDonough KA. A family of acr-Coregulated Mycobacterium tuberculosis genes shares a common DNA motif and requires Rv3133c (dosR or devR) for Expression. Infect Immun 2003; 71(9): 5332-43.
    • (2003) Infect Immun , vol.71 , Issue.9 , pp. 5332-5343
    • Florczyk, M.A.1    McCue, L.A.2    Purkayastha, A.3    Currenti, E.4    Wolin, M.J.5    McDonough, K.A.6
  • 41
    • 0042140672 scopus 로고    scopus 로고
    • Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis persistence program
    • Voskuil MI, Schnappinger D, Harrell MI, Visconti KC, Dolganov GM, Sherman DR, et al. Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis persistence program. J Exp Med 2002; 198(5): 705-13.
    • (2002) J Exp Med , vol.198 , Issue.5 , pp. 705-713
    • Voskuil, M.I.1    Schnappinger, D.2    Harrell, M.I.3    Visconti, K.C.4    Dolganov, G.M.5    Sherman, D.R.6
  • 42
    • 0036951936 scopus 로고    scopus 로고
    • Mycobacterium bovis BCG response regulator essential for hypoxic dormancy
    • Boon C, Dick T. Mycobacterium bovis BCG response regulator essential for hypoxic dormancy. J Bacteriol 2002; 184(24): 6760-7.
    • (2002) J Bacteriol , vol.184 , Issue.24 , pp. 6760-6767
    • Boon, C.1    Dick, T.2
  • 43
    • 0032519735 scopus 로고    scopus 로고
    • Effects of aminoguanidine on latent murine tuberculosis
    • Flynn JL, Scanga CA, Tanaka KE, Chan J. Effects of aminoguanidine on latent murine tuberculosis. J Immun 1998; 160: 1796-803.
    • (1998) J Immun , vol.160 , pp. 1796-1803
    • Flynn, J.L.1    Scanga, C.A.2    Tanaka, K.E.3    Chan, J.4
  • 45
    • 0037099341 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in the tuberculous human lung
    • Nathan C. Inducible nitric oxide synthase in the tuberculous human lung. Amer J Resp Crit Care Med 2002; 166: 130-1.
    • (2002) Amer J Resp Crit Care Med , vol.166 , pp. 130-131
    • Nathan, C.1
  • 46
    • 0035185373 scopus 로고    scopus 로고
    • What is the role of nitric oxide in murine and human host defense against tuberculosis?
    • Chan ED, Chan J, Schluger NW. What is the role of nitric oxide in murine and human host defense against tuberculosis? Am J Respir Cell Mol Biol 2001; 25: 606-12.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 606-612
    • Chan, E.D.1    Chan, J.2    Schluger, N.W.3
  • 47
    • 62449219456 scopus 로고    scopus 로고
    • Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models
    • Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, et al. Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models. Infect Immun 2010; 77(3): 1230-7.
    • (2010) Infect Immun , vol.77 , Issue.3 , pp. 1230-1237
    • Converse, P.J.1    Karakousis, P.C.2    Klinkenberg, L.G.3    Kesavan, A.K.4    Ly, L.H.5    Allen, S.S.6
  • 49
    • 3042790827 scopus 로고    scopus 로고
    • Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: A model for persistent organisms?
    • Hampshire T, Soneji S, Bacon J, James BW, Hinds J, Laing K, et al. Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: A model for persistent organisms? Tuberculosis 2004; 84: 228-38.
    • (2004) Tuberculosis , vol.84 , pp. 228-238
    • Hampshire, T.1    Soneji, S.2    Bacon, J.3    James, B.W.4    Hinds, J.5    Laing, K.6
  • 50
    • 0036270739 scopus 로고    scopus 로고
    • Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling
    • Betts JC, Lukey PT, Robb LC, McAdam RA, Duncap K. Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol Microbiol 2002; 43(3): 717-31.
    • (2002) Mol Microbiol , vol.43 , Issue.3 , pp. 717-731
    • Betts, J.C.1    Lukey, P.T.2    Robb, L.C.3    McAdam, R.A.4    Duncap, K.5
  • 51
    • 0242407462 scopus 로고    scopus 로고
    • Starvation survival response of Mycobacterium tuberculosis
    • Parish T. Starvation survival response of Mycobacterium tuberculosis. J Bacteriol 2003; 185(22): 6702-6.
    • (2003) J Bacteriol , vol.185 , Issue.22 , pp. 6702-6706
    • Parish, T.1
  • 52
    • 70349307297 scopus 로고    scopus 로고
    • Phosphate depletion: A novel trigger for Mycobacterium tuberculosis persistence
    • Rifat D, Bishai WR, Karakousis PC. Phosphate depletion: A novel trigger for Mycobacterium tuberculosis persistence. J Infect Dis 2009; 200(7): 1126-35.
    • (2009) J Infect Dis , vol.200 , Issue.7 , pp. 1126-1135
    • Rifat, D.1    Bishai, W.R.2    Karakousis, P.C.3
  • 53
    • 67650655950 scopus 로고    scopus 로고
    • A Novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drugtolerant, dormant pathogen
    • Deb C, Lee C-M, Dubey VS, Daneil J, Abomoelak B, Sirakova TD, et al. A Novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drugtolerant, dormant pathogen. PLOS One 2009; 4(6): 1-15.
    • (2009) PLOS One , vol.4 , Issue.6 , pp. 1-15
    • Deb, C.1    Lee, C.-M.2    Dubey, V.S.3    Daneil, J.4    Abomoelak, B.5    Sirakova, T.D.6
  • 54
    • 57749196742 scopus 로고    scopus 로고
    • Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions
    • Kim S-Y, Lee B-S, Shin SJ, Kim H-J, Park J-K. Differentially expressed genes in Mycobacterium tuberculosis H37Rv under mild acidic and hypoxic conditions. J Med Microbiol 2008; 57: 1473-80.
    • (2008) J Med Microbiol , vol.57 , pp. 1473-1480
    • Kim, S.-Y.1    Lee, B.-S.2    Shin, S.J.3    Kim, H.-J.4    Park, J.-K.5
  • 55
    • 49649095474 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
    • Kumar A, Deshane JS, Crossman DK, Bolisetty S, Yan B-S, Kramnik I, et al. Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon. J Biol Chem 2008; 283(26): 18032-9.
    • (2008) J Biol Chem , vol.283 , Issue.26 , pp. 18032-18039
    • Kumar, A.1    Deshane, J.S.2    Crossman, D.K.3    Bolisetty, S.4    Yan, B.-S.5    Kramnik, I.6
  • 56
    • 20144385739 scopus 로고    scopus 로고
    • Inhibitors of type II NADH: Menaquinone oxidoreductase represent a class of antitubercular drugs
    • Weinstein EA, Yano T, Li L-S, Avarbock D, Avarbock A, Helm D, et al. Inhibitors of type II NADH: Menaquinone oxidoreductase represent a class of antitubercular drugs. Proc Natl Acad Sci USA 2005; 102(12): 4548-53.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.12 , pp. 4548-4553
    • Weinstein, E.A.1    Yano, T.2    Li, L.-S.3    Avarbock, D.4    Avarbock, A.5    Helm, D.6
  • 57
    • 33744957049 scopus 로고    scopus 로고
    • Steady-state Kinetics and Inhibitory Action of Antitubercular Phenothiazines on Mycobacterium tuberculosis Type-II NADH-Menaquinone Oxidoreductase (NDH-2)
    • Yaho T, Li L-S, Weinstein E, Teh J-S, Rubin H. Steady-state Kinetics and Inhibitory Action of Antitubercular Phenothiazines on Mycobacterium tuberculosis Type-II NADH-Menaquinone Oxidoreductase (NDH-2). J Biol Chem 2006; 281(17): 11456-63.
    • (2006) J Biol Chem , vol.281 , Issue.17 , pp. 11456-11463
    • Yaho, T.1    Li, L.-S.2    Weinstein, E.3    Teh, J.-S.4    Rubin, H.5
  • 58
    • 50149113470 scopus 로고    scopus 로고
    • The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis
    • Rao SPS, Alonso S, Rand L, Dick T, Pethe K. The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2008; 105(33): 11945-50.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.33 , pp. 11945-11950
    • Rao, S.P.S.1    Alonso, S.2    Rand, L.3    Dick, T.4    Pethe, K.5
  • 59
    • 77953161443 scopus 로고    scopus 로고
    • Respiratory ATP synthesis: The new generation of mycobacterial drug targets?
    • Bald D, Koul A. Respiratory ATP synthesis: The new generation of mycobacterial drug targets? FEMS Microbiol Lett 2010; 308(1): 1-7.
    • (2010) FEMS Microbiol Lett , vol.308 , Issue.1 , pp. 1-7
    • Bald, D.1    Koul, A.2
  • 60
    • 3142673470 scopus 로고    scopus 로고
    • 2+ dependence and inhibitory effects of trifluoperazine on plasma membrane ATPase of Thermoactinomyces vulgaris
    • 2+ dependence and inhibitory effects of trifluoperazine on plasma membrane ATPase of Thermoactinomyces vulgaris. Curr Microbiol 2004; 49(1): 28-31.
    • (2004) Curr Microbiol , vol.49 , Issue.1 , pp. 28-31
    • Bhatnagar, K.1    Singh, V.P.2
  • 62
    • 77956319845 scopus 로고    scopus 로고
    • A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine
    • Dutta NK, Mehra S, Kaushal D. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine. PLOS One 2010; 5(4): 1-10.
    • (2010) PLOS One , vol.5 , Issue.4 , pp. 1-10
    • Dutta, N.K.1    Mehra, S.2    Kaushal, D.3
  • 63
    • 68949110351 scopus 로고    scopus 로고
    • Efflux-mediated drug resistance in bacteria: An update
    • Liz XZ, Nikaido H. Efflux-mediated drug resistance in bacteria: an update. Drugs 2009; 69(12): 1555-623.
    • (2009) Drugs , vol.69 , Issue.12 , pp. 1555-1623
    • Liz, X.Z.1    Nikaido, H.2
  • 64
    • 42149168442 scopus 로고    scopus 로고
    • Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis
    • Rodrigues L, Wagner D, Viveiros M, Sampaio D, Couto I, Vavra M, et al. Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis. J Antimicro Chem 2008; 61(5): 1076-82.
    • (2008) J Antimicro Chem , vol.61 , Issue.5 , pp. 1076-1082
    • Rodrigues, L.1    Wagner, D.2    Viveiros, M.3    Sampaio, D.4    Couto, I.5    Vavra, M.6
  • 65
    • 33646842666 scopus 로고    scopus 로고
    • Thioridazine reduces resistance of methicillinresistant Staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump
    • Kristiansen MM, Leandro C, Ordway D, Martins M, Viveiros M, Pacheco T, et al. Thioridazine reduces resistance of methicillinresistant Staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump. In vivo 2006; 20(3): 361-6.
    • (2006) In Vivo , vol.20 , Issue.3 , pp. 361-366
    • Kristiansen, M.M.1    Leandro, C.2    Ordway, D.3    Martins, M.4    Viveiros, M.5    Pacheco, T.6
  • 67
    • 0031057694 scopus 로고    scopus 로고
    • Inhibition of the transport function of membrane proteins by some substituted phenothiazines
    • E. coli and multidrug resistant tumor cells
    • Molnar J, Hever A, Fakla I, Fischer J, Ocsovski I, Aszalos A. Inhibition of the transport function of membrane proteins by some substituted phenothiazines in E. coli and multidrug resistant tumor cells. Anticancer Res 1997; 17(1A): 481-6.
    • (1997) Anticancer Res , vol.17 , Issue.1 A , pp. 481-486
    • Molnar, J.1    Hever, A.2    Fakla, I.3    Fischer, J.4    Ocsovski, I.5    Aszalos, A.6
  • 68
    • 0035098674 scopus 로고    scopus 로고
    • Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines
    • Viveiros M, Amaral L. Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines. Inter J Antimicro Agents 2001; 17: 225-8.
    • (2001) Inter J Antimicro Agents , vol.17 , pp. 225-228
    • Viveiros, M.1    Amaral, L.2
  • 69
    • 0030462751 scopus 로고    scopus 로고
    • Inhibition of the respiration of multi-drug resistant clinical isolated of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis
    • Amaral L, Kristiansen JE, Abebe LS, Millett W. Inhibition of the respiration of multi-drug resistant clinical isolated of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis. J Antimicro Chemo 1996; 38: 1049-53.
    • (1996) J Antimicro Chemo , vol.38 , pp. 1049-1053
    • Amaral, L.1    Kristiansen, J.E.2    Abebe, L.S.3    Millett, W.4
  • 71
    • 0037416986 scopus 로고    scopus 로고
    • Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis
    • Ordway D, Viveiros M, Leandro C, Betterncourt R, Almeida J, Martins M, et al. Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. Antimicro Agents Chemotherap 2003; 47(3): 917-22.
    • (2003) Antimicro Agents Chemotherap , vol.47 , Issue.3 , pp. 917-922
    • Ordway, D.1    Viveiros, M.2    Leandro, C.3    Betterncourt, R.4    Almeida, J.5    Martins, M.6
  • 72
    • 0033839994 scopus 로고    scopus 로고
    • Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis
    • Bettencourt MV, Bosne-David S, Amaral L. Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis. Inter J Antimicro Agents 2000; 16: 69-71.
    • (2000) Inter J Antimicro Agents , vol.16 , pp. 69-71
    • Bettencourt, M.V.1    Bosne-David, S.2    Amaral, L.3
  • 73
    • 0035010729 scopus 로고    scopus 로고
    • Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: A review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy
    • Amaral L, Kristiansen JE, Viveiros M, Atouguia J. Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: A review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy. J Antimicro Chemo 2001; 47: 505-11.
    • (2001) J Antimicro Chemo , vol.47 , pp. 505-511
    • Amaral, L.1    Kristiansen, J.E.2    Viveiros, M.3    Atouguia, J.4
  • 74
    • 52449123326 scopus 로고    scopus 로고
    • Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps
    • Amaral L, Martins M, Viveiros M, Molnar J, Kristiansen JE. Promising therapy of XDR-TB/MDR-TB with thioridazine an inhibitor of bacterial efflux pumps. Curr Drug Targ 2008; 9: 816-19.
    • (2008) Curr Drug Targ , vol.9 , pp. 816-819
    • Amaral, L.1    Martins, M.2    Viveiros, M.3    Molnar, J.4    Kristiansen, J.E.5
  • 75
    • 0027052626 scopus 로고
    • Chlorpromazine: A drug potentially useful for treating mycobacterial infections
    • Crowle AJ, Doubas GS, May MH. Chlorpromazine: A drug potentially useful for treating mycobacterial infections. Chemotherapy 1992; 38(6): 410-19.
    • (1992) Chemotherapy , vol.38 , Issue.6 , pp. 410-419
    • Crowle, A.J.1    Doubas, G.S.2    May, M.H.3
  • 76
    • 40749110626 scopus 로고    scopus 로고
    • + transport enhance intracellular killing of M. tuberculosis by nonkilling macrophages
    • + transport enhance intracellular killing of M. tuberculosis by nonkilling macrophages. In vivo 2008; 22(1): 69-75.
    • (2008) In Vivo , vol.22 , Issue.1 , pp. 69-75
    • Martins, M.1    Viveiros, M.2    Amaral, L.3
  • 77
    • 78651129576 scopus 로고
    • Clinical, biochemical and post mortem studies on a patient treated with chlorpromazine
    • Forrest FM, Forrest IS, Roizin L. Clinical, biochemical and post mortem studies on a patient treated with chlorpromazine. Agressologie 1963; 4: 259-65.
    • (1963) Agressologie , vol.4 , pp. 259-265
    • Forrest, F.M.1    Forrest, I.S.2    Roizin, L.3
  • 78
    • 35648948351 scopus 로고    scopus 로고
    • The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis
    • Martins M, Viveiros M, Kristiansen JE, Molnar J, Amaral L. The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis. In vivo 2007; 21: 771-6.
    • (2007) In Vivo , vol.21 , pp. 771-776
    • Martins, M.1    Viveiros, M.2    Kristiansen, J.E.3    Molnar, J.4    Amaral, L.5
  • 79
    • 77958612298 scopus 로고    scopus 로고
    • The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis
    • van Soolingen D, Hernandez-Pando R, Orozco H, Aguilar D, Magis-Escurra C, Amaral L, et al. The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLOS One 2010; 5(9): 1-6.
    • (2010) PLOS One , vol.5 , Issue.9 , pp. 1-6
    • van Soolingen, D.1    Hernandez-Pando, R.2    Orozco, H.3    Aguilar, D.4    Magis-Escurra, C.5    Amaral, L.6
  • 80
    • 4544360624 scopus 로고    scopus 로고
    • Treatment completion and costs of a randomized trial of rifampin for 4 months versus isoniazid for 9 months
    • Menzles D, Dion MJ, Rabinovitch B, Mannix S, Brassard P, Schwartzman K. Treatment completion and costs of a randomized trial of rifampin for 4 months versus isoniazid for 9 months. Am J Resp Crit Care Med 2004; 170(4): 445-9.
    • (2004) Am J Resp Crit Care Med , vol.170 , Issue.4 , pp. 445-449
    • Menzles, D.1    Dion, M.J.2    Rabinovitch, B.3    Mannix, S.4    Brassard, P.5    Schwartzman, K.6
  • 81
    • 0020359975 scopus 로고
    • Efficacy of various durations of isoniazid preventive therapy for tuberculosis: Five years of follow-up in the IUAT trial. International union against tuberculosis committee on prophylaxis
    • Efficacy of various durations of isoniazid preventive therapy for tuberculosis: five years of follow-up in the IUAT trial. International union against tuberculosis committee on prophylaxis. Bull World Health Organ 1982; 60(4): 555-64.
    • (1982) Bull World Health Organ , vol.60 , Issue.4 , pp. 555-564
  • 82
    • 27644588268 scopus 로고    scopus 로고
    • Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates
    • Xie Z, Siddiqi N, Rubin EJ. Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates. Antimicro Agents Chemotherap 2005; 49(11): 4778-80.
    • (2005) Antimicro Agents Chemotherap , vol.49 , Issue.11 , pp. 4778-4780
    • Xie, Z.1    Siddiqi, N.2    Rubin, E.J.3
  • 83
    • 76849095708 scopus 로고    scopus 로고
    • Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability
    • Gengenbacher M, Rao SPS, Pethe K, Dick T. Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability. Microbiology 2010; 156: 81-7.
    • (2010) Microbiology , vol.156 , pp. 81-87
    • Gengenbacher, M.1    Rao, S.P.S.2    Pethe, K.3    Dick, T.4
  • 84
    • 9144263752 scopus 로고    scopus 로고
    • Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions
    • Starck J, Kalenius G, Marklund B-I, Andersson DI, Akerlund T. Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions. Microbiology 2004; 150: 3821-9.
    • (2004) Microbiology , vol.150 , pp. 3821-3829
    • Starck, J.1    Kalenius, G.2    Marklund, B.-I.3    Andersson, D.I.4    Akerlund, T.5
  • 85
    • 54449084104 scopus 로고    scopus 로고
    • Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis
    • Koul A, Vranckx L, Dendouga N, Balemans W, Van den Wyngaert I, Vergauwen K, et al. Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis. J Biol Chem 2008; 283(37): 25273-80.
    • (2008) J Biol Chem , vol.283 , Issue.37 , pp. 25273-25280
    • Koul, A.1    Vranckx, L.2    Dendouga, N.3    Balemans, W.4    Van den, W.I.5    Vergauwen, K.6
  • 86
    • 78149425904 scopus 로고    scopus 로고
    • Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses
    • Tan MP, Sequeira P, Lin WW, Phong WY, Cliff P, Ng SH, et al. Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses. PLOS One 2010; 5(10): 1-8.
    • (2010) PLOS One , vol.5 , Issue.10 , pp. 1-8
    • Tan, M.P.1    Sequeira, P.2    Lin, W.W.3    Phong, W.Y.4    Cliff, P.5    Ng, S.H.6
  • 87
    • 78049499892 scopus 로고    scopus 로고
    • Picking up the pace - scale-up of MDR tuberculosis treatment programs
    • Keshavjee S, Farmer PE. Picking up the pace - scale-up of MDR tuberculosis treatment programs. New Engl J Med 2010; 363(19): 1781-4.
    • (2010) New Engl J Med , vol.363 , Issue.19 , pp. 1781-1784
    • Keshavjee, S.1    Farmer, P.E.2
  • 88
    • 79959930350 scopus 로고    scopus 로고
    • The global fund to fight AIDS
    • Funding options paper - thirteenth board meeting, Geneva, Apr 27
    • Funding options paper - thirteenth board meeting. The global fund to fight AIDS. Tuberculosis Malaria, Geneva 2010; 10 Apr 27.
    • (2010) Tuberculosis Malaria , vol.10
  • 89
    • 79952051218 scopus 로고    scopus 로고
    • Multi-drug resistant tuberculosis in Chuuk State, Federated States of Micronesia, 2008-2009
    • Fred D, Desai M, Song R, Bamrah S, Pavlin BI, Heetderks A, et al. Multi-drug resistant tuberculosis in Chuuk State, Federated States of Micronesia, 2008-2009. Pacific Health Dialog 2010; 16(1): 123-7.
    • (2010) Pacific Health Dialog , vol.16 , Issue.1 , pp. 123-127
    • Fred, D.1    Desai, M.2    Song, R.3    Bamrah, S.4    Pavlin, B.I.5    Heetderks, A.6
  • 90
    • 0014038880 scopus 로고
    • Role of chlorpromazine in the treatment of pulmonary tuberculosis in psychiatric patients
    • Kaminska M. Role of chlorpromazine in the treatment of pulmonary tuberculosis in psychiatric patients. Folia Medica Cracoviensia 1967; 9: 115-43.
    • (1967) Folia Medica Cracoviensia , vol.9 , pp. 115-143
    • Kaminska, M.1
  • 91
    • 77950260778 scopus 로고    scopus 로고
    • Tuberculosis extensamente resistente (XDR-TB) en Argentina: Aspectos destacables epidemiológicos, bacteriológicos, terapéuticos y evolutivos
    • Abbate E, Vescovo M, Natiello M, Cufré M, García A, Ambroggi M, et al. Tuberculosis extensamente resistente (XDR-TB) en Argentina: Aspectos destacables epidemiológicos, bacteriológicos, terapéuticos y evolutivos. Rev Argen Med Respir 2010; 1: 19-25.
    • (2010) Rev Argen Med Respir , vol.1 , pp. 19-25
    • Abbate, E.1    Vescovo, M.2    Natiello, M.3    Cufré, M.4    García, A.5    Ambroggi, M.6
  • 92
    • 33846969173 scopus 로고    scopus 로고
    • In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis
    • Martins M, Schelz Z, Martins A, Molnar J, Hajõs G, Riedl Z, et al. In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis. Inter J Antimicro Agents 2007; 29: 338-40.
    • (2007) Inter J Antimicro Agents , vol.29 , pp. 338-340
    • Martins, M.1    Schelz, Z.2    Martins, A.3    Molnar, J.4    Hajõs, G.5    Riedl, Z.6
  • 93
    • 77954066432 scopus 로고    scopus 로고
    • Therapy of XDR TB with thioridazine a drug beyond patent protection but eligible for patent As New Use
    • Amaral L, Molnar J. Therapy of XDR TB with thioridazine a drug beyond patent protection but eligible for patent As New Use. Rec Pat Anti-Infect Drug Discov 2010; 5: 109-14.
    • (2010) Rec Pat Anti-Infect Drug Discov , vol.5 , pp. 109-114
    • Amaral, L.1    Molnar, J.2
  • 95
    • 35248895271 scopus 로고    scopus 로고
    • Thioridazine: Resurrection as an antimicrobial agent
    • Thanacoody HKR. Thioridazine: Resurrection as an antimicrobial agent. Brit J Clin Pharmac 2007; 64(5): 566-71.
    • (2007) Brit J Clin Pharmac , vol.64 , Issue.5 , pp. 566-571
    • Thanacoody, H.K.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.