PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions

Cell Death and Disease

Volumn 2, Issue 5, 2011, Pages

  Hara, T ^a   Miyazaki, M ^a   Hakuno, F ^a   Takahashi, S ^a   Chida, K ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

3D Organotypic coculture; Differentiation; Growth arrest; Keratinocytes; P27Kip1; PKC

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C ETA; STRESS ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE 1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRESS; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; GENE INDUCTION; GROWTH DISORDER; KERATINOCYTE; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; THICKNESS; UPREGULATION; ADENOVIRUS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL STRAIN HEK293; CYTOLOGY; EPIDERMIS; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; PHYSIOLOGICAL STRESS;

ADENOVIRIDAE; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; EPIDERMIS; FIBROBLASTS; HEK293 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KERATINOCYTES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 8; PROTEIN KINASE C; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSFECTION; UP-REGULATION;

EID: 79959924336     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.40     Document Type: Article

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